$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

[해외논문] Mitochondrial proton leak and the uncoupling protein 1 homologues

Biochimica et biophysica acta, Bioenergetics, v.1504 no.1, 2001년, pp.144 - 158  

Stuart, J.A (MRC Dunn Human Nutrition Unit, Hills Road, Cambridge CB2 2XY, UK) ,  Cadenas, S (MRC Dunn Human Nutrition Unit, Hills Road, Cambridge CB2 2XY, UK) ,  Jekabsons, M.B (MRC Dunn Human Nutrition Unit, Hills Road, Cambridge CB2 2XY, UK) ,  Roussel, D (MRC Dunn Human Nutrition Unit, Hills Road, Cambridge CB2 2XY, UK) ,  Brand, M.D (MRC Dunn Human Nutrition Unit, Hills Road, Cambridge CB2 2XY, UK)

Abstract AI-Helper 아이콘AI-Helper

AbstractMitochondrial proton leak is the largest single contributor to the standard metabolic rate (SMR) of a rat, accounting for about 20% of SMR. Yet the mechanisms by which proton leak occurs are incompletely understood. The available evidence suggests that both phospholipids and proteins in the ...

Keyword

참고문헌 (77)

  1. Biochim. Biophys. Acta Brand 1018 128 1990 10.1016/0005-2728(90)90232-S The proton leak across the mitochondrial inner membrane 

  2. Biochim. Biophys. Acta Brown 1059 55 1991 10.1016/S0005-2728(05)80187-2 On the nature of the mitochondrial proton leak 

  3. Biochim. Biophys. Acta Brand 1187 132 1994 10.1016/0005-2728(94)90099-X The causes and functions of mitochondrial proton leak 

  4. Int. J. Obes. Relat. Metab. Disord. Brand 23 Suppl 6 S4 1999 10.1038/sj.ijo.0800936 The significance and mechanism of mitochondrial proton conductance 

  5. Am. J. Physiol. Rolfe 271 C1380 1996 10.1152/ajpcell.1996.271.4.C1380 Contribution of mitochondrial proton leak to skeletal muscle respiration and to standard metabolic rate 

  6. Am. J. Physiol. Rolfe 276 C692 1999 10.1152/ajpcell.1999.276.3.C692 Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR 

  7. Biochim. Biophys. Acta Rolfe 1188 405 1994 10.1016/0005-2728(94)90062-0 Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat 

  8. Biochim. Biophys. Acta Krauss 1412 129 1999 10.1016/S0005-2728(99)00058-4 Effects of the mitogen concanavalin A on pathways of thymocyte energy metabolism 

  9. Int. J. Obes. Relat. Metab. Disord. Porter 23 Suppl. 6 S12 1999 10.1038/sj.ijo.0800937 Indirect measurement of mitochondrial proton leak and its application 

  10. J. Bioenerg. Biomembr. Deamer 19 457 1987 10.1007/BF00770030 Proton permeation of lipid bilayers 

  11. Biochim. Biophys. Acta Elamrani 727 22 1983 10.1016/0005-2736(83)90364-4 Effect of the lipid phase transition on the kinetics of H+/OH− diffusion across phosphatidic acid bilayers 

  12. Biophys. J. Fuks 66 1404 1994 10.1016/S0006-3495(94)80931-2 Permeability and electrical properties of planar lipid membranes from thylakoid lipids 

  13. Biochemistry Hauser 12 4507 1973 10.1021/bi00746a032 Mechanism of ion escape from phosphatidylcholine and phosphatidylserine single bilayer vesicles 

  14. Biophys. J. Paula 70 339 1996 10.1016/S0006-3495(96)79575-9 Permeation of protons, potassium ions, and small polar molecules through phospholipid bilayers as a function of membrane thickness 

  15. Biochim. Biophys. Acta Brookes 1330 157 1997 10.1016/S0005-2736(97)00160-0 The proton permeability of liposomes made from mitochondrial inner membrane phospholipids: no effect of fatty acid composition 

  16. J. Membr. Biol. Brookes 155 167 1997 10.1007/s002329900168 The proton permeability of liposomes made from mitochondrial inner membrane phospholipids: comparison with isolated mitochondria 

  17. Comp. Biochem. Physiol. B Brookes 119 325 1998 10.1016/S0305-0491(97)00357-X The proton permeability of the inner membrane of liver mitochondria from ectothermic and endothermic vertebrates and from obese rats: correlations with standard metabolic rate and phospholipid fatty acid composition 

  18. Biochemistry Krishnamoorthy 23 1640 1984 10.1021/bi00303a009 Non-ohmic proton conductance of mitochondria and liposomes 

  19. Biochem. J. O’Shea 219 401 1984 10.1042/bj2190401 The relationship between the rate of respiration and the protonmotive force. The role of proton conductivity 

  20. Am. J. Physiol. Porter 271 R1550 1996 Allometry of mitochondrial proton leak: influence of membrane surface area and fatty acid composition 

  21. Biochim. Biophys. Acta Fontaine 1276 181 1996 10.1016/0005-2728(96)00075-8 Effect of polyunsaturated fatty acids deficiency on oxidative phosphorylation in rat liver mitochondria 

  22. Biochem. J. Brand 275 81 1991 10.1042/bj2750081 Evolution of energy metabolism. Proton permeability of the inner membrane of liver mitochondria is greater in a mammal than in a reptile 

  23. Biochemistry Mimms 20 833 1981 10.1021/bi00507a028 Phospholipid vesicle formation and transmembrane protein incorporation using octyl glucoside 

  24. Biochim. Biophys. Acta. Romans 642 135 1981 10.1016/0005-2736(81)90144-9 Incorporation of the transmembrane hydrophobic domain of glycophorin into small unilamellar phospholipid vesicles. Ion flux studies 

  25. Biophys. J. Oliver 66 1364 1994 10.1016/S0006-3495(94)80927-0 α-Helical hydrophobic polypeptides form proton-selective channels in lipid bilayers 

  26. Science Lear 240 1177 1988 10.1126/science.2453923 Synthetic amphiphilic peptide models for protein ion channels (published erratum appeared in Science 245 (1989) 1437) 

  27. Proc. Natl. Acad. Sci. USA Sheldon 93 6399 1996 10.1073/pnas.93.13.6399 31P NMR magnetization transfer study of the control of ATP turnover in Saccharomyces cerevisiae 

  28. Biochim. Biophys. Acta Skulachev 1363 100 1998 10.1016/S0005-2728(97)00091-1 Uncoupling: new approaches to an old problem of bioenergetics 

  29. Trends Biochem. Sci. Klingenberg 15 108 1990 10.1016/0968-0004(90)90194-G Mechanism and evolution of the uncoupling protein of brown adipose tissue 

  30. B. Cannon, A. Matthias, V. Golozoubova, K.B.E. Ohlson, U. Andersson, A. Jacobsson, J. Nedergaard, Unifying and distinguishing features of brown and white adipose tissues: UCP1 versus other UCPs, in: G. Ailhaud, B. Guy-Grands (Eds.), Progress in Obesity Research, John Libbey and Company, 1999, pp. 13-26. 

  31. Am. J. Physiol. Trayhurn 252 E237 1987 Effect of warm or cold exposure on GDP binding and uncoupling protein in rat brown fat 

  32. FEBS Lett. Geloen 267 265 1990 10.1016/0014-5793(90)80941-B Regulation of the level of uncoupling protein in brown adipose tissue by insulin requires the mediation of the sympathetic nervous system 

  33. Biochim. Biophys. Acta Nicholls 549 1 1979 10.1016/0304-4173(79)90016-8 Brown adipose tissue mitochondria 

  34. Am. J. Physiol. Monemdjou 276 E1073 1999 Mitochondrial proton leak in brown adipose tissue mitochondria of UCP1-deficient mice is GDP insensitive 

  35. J. Biol. Chem. Matthias 274 28150 1999 10.1074/jbc.274.40.28150 The bioenergetics of brown fat mitochondria from UCP1-ablated mice. UCP1 is not involved in fatty acid-induced de-energization (‘uncoupling’) 

  36. Nature Genet. Fleury 15 269 1997 10.1038/ng0397-269 Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia 

  37. FEBS Lett. Boss 408 39 1997 10.1016/S0014-5793(97)00384-0 Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression 

  38. Nature Laloi 389 135 1997 10.1038/38156 A plant cold-induced uncoupling protein 

  39. J. Biol. Chem. Nobes 265 12903 1990 10.1016/S0021-9258(19)38245-6 Non-Ohmic proton conductance of the mitochondrial inner membrane in hepatocytes 

  40. J. Bioenerg. Biomembr. Stuart 31 517 1999 10.1023/A:1005456725549 Mitochondrial proton leak and the uncoupling proteins 

  41. Biochim. Biophys. Acta Stuart 1413 50 1999 10.1016/S0005-2728(99)00081-X Uncoupling protein 2 from carp and zebrafish, ectothermic vertebrates 

  42. Int. J. Obes. Ricquier 24 Suppl. 1 S10 2000 The UCP family: where are we? 

  43. FASEB J. Samec 12 715 1998 10.1096/fasebj.12.9.715 Role of UCP homologues in skeletal muscles and brown adipose tissue: mediators of thermogenesis or regulators of lipids as fuel substrate? 

  44. FEBS Lett. Cadenas 462 257 1999 10.1016/S0014-5793(99)01540-9 UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged 

  45. FEBS Lett. Zhang 449 129 1999 10.1016/S0014-5793(99)00441-X Assessment of uncoupling activity of uncoupling protein 3 using a yeast heterologous expression system 

  46. EMBO J. Rial 18 5827 1999 10.1093/emboj/18.21.5827 Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2 

  47. J. Biol. Chem. Sanchis 273 34611 1998 10.1074/jbc.273.51.34611 BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast 

  48. Int. J. Obes. Stuart 24 Suppl. 1 S187 2000 An uncoupling artifact can accompany uncoupling protein-1 expression in yeast mitochondria 

  49. FEBS Lett. Echtay 450 8 1999 10.1016/S0014-5793(99)00460-3 Regulation of UCP3 by nucleotides is different from regulation of UCP1 

  50. J. Biol. Chem. Jaburek 274 26003 1999 10.1074/jbc.274.37.26003 Transport function and regulation of mitochondrial uncoupling proteins 2 and 3 

  51. Eur. J. Biochem. Winkler 207 135 1992 10.1111/j.1432-1033.1992.tb17030.x An improved procedure for reconstitution of the uncoupling protein and in-depth analysis of H+/OH− transport (published erratum appeared in Eur. J. Biochem. 209 (1992) 1063) 

  52. J. Biol. Chem. Winkler 269 2508 1994 10.1016/S0021-9258(17)41974-0 Effect of fatty acids on H+ transport activity of the reconstituted uncoupling protein 

  53. J. Biol. Chem. Murdza-Inglis 269 7435 1994 10.1016/S0021-9258(17)37304-0 A single mutation in uncoupling protein of rat brown adipose tissue mitochondria abolishes GDP sensitivity of H+ transport 

  54. J. Bioenerg. Biomembr. Palmieri 25 525 1993 10.1007/BF01108409 Functional properties of purified and reconstituted mitochondrial metabolite carriers 

  55. Nature Enerback 387 90 1997 10.1038/387090a0 Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese 

  56. Nature Clapham 406 415 2000 10.1038/35019082 Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean 

  57. Int. J. Obes. Cadenas 24 Suppl. 1 S187 2000 Human uncoupling protein-3 overexpression increases mitochondrial proton leak 

  58. J. Biol. Chem. Gong 275 16251 2000 10.1074/jbc.M910177199 Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3 

  59. J. Biol. Chem. Vidal-Puig 275 16258 2000 10.1074/jbc.M910179199 Energy metabolism in uncoupling protein 3 gene knockout mice 

  60. Mol. Cell. Biochem. Papa 174 305 1997 10.1023/A:1006873518427 Reactive oxygen species, mitochondria, apoptosis and aging 

  61. FEBS Lett. Bodrova 435 269 1998 10.1016/S0014-5793(98)01072-2 Membrane potential generation coupled to oxidation of external NADH in liver mitochondria 

  62. Can. J. Physiol. Pharmacol. Ma 64 1252 1986 10.1139/y86-211 Starvation-induced changes in metabolic rate, blood flow, and regional energy expenditure in rats 

  63. J. Biol. Chem. Boss 273 5 1998 10.1074/jbc.273.1.5 Uncoupling protein-3 expression in rodent skeletal muscle is modulated by food intake but not by changes in environmental temperature 

  64. Lancet Boss 351 1933 1998 10.1016/S0140-6736(05)78617-7 Uncoupling protein-3 expression in skeletal muscle and free fatty acids in obesity 

  65. FEBS Lett. Lanni 444 250 1999 10.1016/S0014-5793(99)00061-7 Expression of uncoupling protein-3 and mitochondrial activity in the transition from hypothyroid to hyperthyroid state in rat skeletal muscle 

  66. Am. J. Physiol. Jekabsons 277 E380 1999 T(3) stimulates resting metabolism and UCP-2 and UCP-3 mRNA but not nonphosphorylating mitochondrial respiration in mice 

  67. Am. J. Physiol. Endocrinol. Metab. Yu 279 E433 2000 10.1152/ajpendo.2000.279.2.E433 Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics 

  68. FEBS Lett. Hagen 454 201 1999 10.1016/S0014-5793(99)00811-X Assessment of uncoupling activity of the human uncoupling protein 3 short form and three mutants of the uncoupling protein gene using a yeast heterologous expression system 

  69. Biochemistry Hagen 39 5845 2000 10.1021/bi992980+ Uncoupling proteins 1 and 3 are regulated differently 

  70. Biochem. J. Cadenas 348 209 2000 10.1042/bj3480209 Effects of magnesium and nucleotides on the proton conductance of rat skeletal-muscle mitochondria 

  71. M.B. Jekabsons, B.A. Horwitz, Nucleotide effects on liver and muscle mitochondrial nonphosphorylating respiration and membrane potential, Biochim. Biophys. Acta, in press. 

  72. FEBS Lett. Garlid 438 10 1998 10.1016/S0014-5793(98)01246-0 The mechanism of proton transport mediated by mitochondrial uncoupling proteins 

  73. J. Biol. Chem. Gonzalez-Barroso 273 15528 1998 10.1074/jbc.273.25.15528 The uncoupling protein UCP1 does not increase the proton conductance of the inner mitochondrial membrane by functioning as a fatty acid anion transporter 

  74. Biochim. Biophys. Acta Klingenberg 1415 271 1999 10.1016/S0005-2736(98)00232-6 Structure and function of the uncoupling protein from brown adipose tissue 

  75. Am. J. Physiol. Porter 269 R1213 1995 Causes of differences in respiration rate of hepatocytes from mammals of different body mass 

  76. Comp. Biochem. Physiol. B Savina 120 375 1998 10.1016/S0305-0491(98)10026-3 Respiration and adenine nucleotides of Baltic lamprey (Lampreta fluviatilis l.) hepatocytes during spawning migration 

  77. 10.1007/978-3-662-04162-8_44 M.D. Brand, T. Bishop, R.G. Boutilier, J. St-Pierre, Mitochondrial proton conductance, standard metabolic rate, and metabolic depression, in: G. Heldmaier, M. Klingenspor (Eds.), Life in the Cold, Springer, Berlin, 2000, pp. 413-430. 

활용도 분석정보

상세보기
다운로드
내보내기

활용도 Top5 논문

해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.

관련 콘텐츠

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로