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A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice 원문보기

Frontiers in molecular neuroscience, v.12, 2019년, pp.241 -   

Yook, Chaehyun ,  Kim, Kyungdeok ,  Kim, Doyoun ,  Kang, Hyojin ,  Kim, Sun-Gyun ,  Kim, Eunjoon ,  Kim, Soo Young

초록이 없습니다.

참고문헌 (138)

  1. Mol. Autism Abrahams 4 36 2013 SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs) 10.1186/2040-2392-4-36 

  2. Methods of Behavior Analysis in Neuroscience Bailey 1 2009 Anxiety-related behaviors in mice 

  3. Nat. Neurosci. Barak 19 647 2016 Neurobiology of social behavior abnormalities in autism and Williams syndrome 10.1038/nn.4276 

  4. Mol. Psychiatry Barnes 20 1161 2015 Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders 10.1038/mp.2015.113 

  5. Eur. J. Neurosci. Bayatti 28 1449 2008 Progressive loss of PAX6, TBR2, NEUROD and TBR1 mRNA gradients correlates with translocation of EMX2 to the cortical plate during human cortical development 10.1111/j.1460-9568.2008.06475.x 

  6. Proc. Natl. Acad. Sci. U S A Bedogni 107 13129 2010 Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex 10.1073/pnas.1002285107 

  7. Curr. Opin. Neurobiol. Bourgeron 19 231 2009 A synaptic trek to autism 10.1016/j.conb.2009.06.003 

  8. Nat. Rev. Neurosci. Bourgeron 16 551 2015 From the genetic architecture to synaptic plasticity in autism spectrum disorder 10.1038/nrn3992 

  9. Genome Med. Bowling 9 43 2017 Genomic diagnosis for children with intellectual disability and/or developmental delay 10.1186/s13073-017-0433-1 

  10. Brain Res. Bull. Brambilla 61 557 2003 Brain anatomy and development in autism: review of structural MRI studies 10.1016/j.brainresbull.2003.06.001 

  11. Nat. Rev. Neurosci. Bramham 8 776 2007 Dendritic mRNA: transport, translation and function 10.1038/nrn2150 

  12. Curr. Opin. Neurobiol. Budnik 21 151 2011 Wnt signaling during synaptic development and plasticity 10.1016/j.conb.2010.12.002 

  13. Neuron Bulfone 15 63 1995 T-brain-1: a homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex 10.1016/0896-6273(95)90065-9 

  14. Neuron Bulfone 21 1273 1998 An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons 10.1016/s0896-6273(00)80647-9 

  15. Neurosci. Biobehav. Rev. Burgdorf 35 1831 2011 Frequency-modulated 50 kHz ultrasonic vocalizations: a tool for uncovering the molecular substrates of positive affect 10.1016/j.neubiorev.2010.11.011 

  16. Cogn. Emot. Campbell 28 46 2014 Does anxiety sensitivity correlate with startle habituation? An examination in two independent samples 10.1080/02699931.2013.799062 

  17. J. Neurosci. Canovas 35 7552 2015 The specification of cortical subcerebral projection neurons depends on the direct repression of TBR1 by CTIP1/BCL11a 10.1523/jneurosci.0169-15.2015 

  18. Neuron Cao 98 670 2018 γ oscillation dysfunction in mpfc leads to social deficits in neuroligin 3 R451C knockin mice 10.1016/j.neuron.2018.04.025 

  19. J. Neurosci. Cardin 36 10496 2016 Snapshots of the brain in action: local circuit operations through the lens of γ oscillations 10.1523/jneurosci.1021-16.2016 

  20. Nature Cardin 459 663 2009 Driving fast-spiking cells induces γ rhythm and controls sensory responses 10.1038/nature08002 

  21. Cancer Cell Chiang 26 773 2014 Controlling COR competence: BCL-6 regulates neurogenesis and tumor suppression 10.1016/j.ccell.2014.11.020 

  22. Front. Cell. Neurosci. Chuang 8 280 2014 Neuronal excitation upregulates Tbr1, a high-confidence risk gene of autism, mediating Grin2b expression in the adult brain 10.3389/fncel.2014.00280 

  23. Autism Res. Chuang 8 412 2015 T-brain-1-a potential master regulator in autism spectrum disorders 10.1002/aur.1456 

  24. Cold Spring Harb. Perspect. Biol. Chung 7 a020370 2015 Astrocytes control synapse formation, function, and elimination 10.1101/cshperspect.a020370 

  25. Nat. Rev. Neurosci. Clarke 14 311 2013 Emerging roles of astrocytes in neural circuit development 10.1038/nrn3484 

  26. Neuron Courchesne 56 399 2007 Mapping early brain development in autism 10.1016/j.neuron.2007.10.016 

  27. Ment. Retard. Dev. Disabil. Res. Rev. Crawley 10 248 2004 Designing mouse behavioral tasks relevant to autistic-like behaviors 10.1002/mrdd.20039 

  28. Eur. Neuropsychopharmacol. Darvas 19 670 2009 Modulation of the Ca2+ conductance of nicotinic acetylcholine receptors by Lypd6 10.1016/j.euroneuro.2009.03.007 

  29. Nat. Med. de la Torre-Ubieta 22 345 2016 Advancing the understanding of autism disease mechanisms through genetics 10.1038/nm.4071 

  30. Curr. Neurol. Neurosci. Rep. De Rubeis 15 36 2015 Recent advances in the genetics of autism spectrum disorder 10.1007/s11910-015-0553-1 

  31. Nature De Rubeis 515 209 2014 Synaptic, transcriptional and chromatin genes disrupted in autism 10.1038/nature13772 

  32. J. Neurosci. Delevich 35 5743 2015 The mediodorsal thalamus drives feedforward inhibition in the anterior cingulate cortex via parvalbumin interneurons 10.1523/jneurosci.4565-14.2015 

  33. Sci. Rep. den Hoed 8 14279 2018 Functional characterization of TBR1 variants in neurodevelopmental disorder 10.1038/s41598-018-32053-6 

  34. Nat. Commun. Deriziotis 5 4954 2014 De novo TBR1 mutations in sporadic autism disrupt protein functions 10.1038/ncomms5954 

  35. Nat. Rev. Neurosci. Dityatev 11 735 2010 The dual role of the extracellular matrix in synaptic plasticity and homeostasis 10.1038/nrn2898 

  36. Neuron Dwyer 29 309 2001 Tbr1 conducts the orchestration of early cortical development 10.1016/s0896-6273(01)00202-1 

  37. Curr. Opin. Neurol. Ebrahimi-Fakhari 28 91 2015 Autism and the synapse: emerging mechanisms and mechanism-based therapies 10.1097/wco.0000000000000186 

  38. Front. Neurosci. Elsen 12 571 2018 The epigenetic factor landscape of developing neocortex is regulated by transcription factors Pax6-> Tbr2-> Tbr1 10.3389/fnins.2018.00571 

  39. Curr. Opin. Neurobiol. Enard 21 415 2011 FOXP2 and the role of cortico-basal ganglia circuits in speech and language evolution 10.1016/j.conb.2011.04.008 

  40. Nature Enard 418 869 2002 Molecular evolution of FOXP2, a gene involved in speech and language 10.1038/nature01025 

  41. J. Neurosci. Englund 25 247 2005 Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells and postmitotic neurons in developing neocortex 10.1523/jneurosci.2899-04.2005 

  42. Cell Eroglu 139 380 2009 Gabapentin receptor α2δ-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis 10.1016/j.cell.2009.09.025 

  43. Brain Res. Rev. Faissner 63 26 2010 Contributions of astrocytes to synapse formation and maturation-Potential functions of the perisynaptic extracellular matrix 10.1016/j.brainresrev.2010.01.001 

  44. Neuron Fazel Darbandi 100 831.e7 2018 Neonatal Tbr1 dosage controls cortical layer 6 connectivity 10.1016/j.neuron.2018.09.027 

  45. Proc. Natl. Acad. Sci. U S A Field 103 17537 2006 Identification of the α2-δ-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin 10.1073/pnas.0409066103 

  46. Mol. Brain Filice 9 10 2016 Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism 10.1186/s13041-016-0192-8 

  47. Protein Sci. Fiser 9 1753 2000 Modeling of loops in protein structures 10.1110/ps.9.9.1753 

  48. Trends Genet. Fisher 25 166 2009 FOXP2 as a molecular window into speech and language 10.1016/j.tig.2009.03.002 

  49. Prog. Brain Res. Frischknecht 214 81 2014 Neural ECM molecules in axonal and synaptic homeostatic plasticity 10.1016/b978-0-444-63486-3.00004-9 

  50. Adv. Exp. Med. Biol. Frischknecht 970 153 2012 The brain’s extracellular matrix and its role in synaptic plasticity 10.1007/978-3-7091-0932-8_7 

  51. Science Garber 317 190 2007 Neuroscience. Autism’s cause may reside in abnormalities at the synapse 10.1126/science.317.5835.190 

  52. Nat. Neurosci. Geisheker 20 1043 2017 Hotspots of missense mutation identify neurodevelopmental disorder genes and functional domains 10.1038/nn.4589 

  53. Gen. Physiol. Biophys. Geisler 34 105 2015 Emerging evidence for specific neuronal functions of auxiliary calcium channel α2δ subunits 10.4149/gpb_2014037 

  54. Mol. Neurobiol. Gerendasy 15 131 1997 RC3/neurogranin, a postsynaptic calpacitin for setting the response threshold to calcium influxes 10.1007/bf02740632 

  55. Curr. Opin. Neurobiol. Golden 48 106 2018 Disrupted circuits in mouse models of autism spectrum disorder and intellectual disability 10.1016/j.conb.2017.11.006 

  56. PLoS Genet. Hamdan 10 e1004772 2014 De novo mutations in moderate or severe intellectual disability 10.1371/journal.pgen.1004772 

  57. Proc. Natl. Acad. Sci. U S A Han 108 3041 2011 TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract 10.1073/pnas.1016723108 

  58. Cereb. Cortex Hashemi 28 690 2018 The number of parvalbumin-expressing interneurons is decreased in the prefrontal cortex in autism 10.1093/cercor/bhx063 

  59. Nature Hazlett 542 348 2017 Early brain development in infants at high risk for autism spectrum disorder 10.1038/nature21369 

  60. J. Comp. Neurol. Hevner 447 8 2002 Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other 10.1002/cne.10219 

  61. Brain Res. Dev. Brain Res. Hevner 141 39 2003 Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin 10.1016/s0165-3806(02)00641-7 

  62. Neuron Hevner 29 353 2001 Tbr1 regulates differentiation of the preplate and layer 6 10.1016/s0896-6273(01)00211-2 

  63. Nature Hsueh 404 298 2000 Nuclear translocation and transcription regulation by the membrane- associated guanylate kinase CASK/LIN-2 10.1038/35005118 

  64. Nat. Protoc. Huang da 4 44 2009 Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources 10.1038/nprot.2008.211 

  65. Nat. Neurosci. Huang 17 240 2014 Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality 10.1038/nn.3626 

  66. Front. Neurosci. Huang 9 406 2015 Brain-specific transcriptional regulator T-brain-1 controls brain wiring and neuronal activity in autism spectrum disorders 10.3389/fnins.2015.00406 

  67. Mol. Autism Huang 10 5 2019 Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice 10.1186/s13229-019-0257-5 

  68. Neuroscience Hulbert 321 3 2016 Monogenic mouse models of autism spectrum disorders: common mechanisms and missing links 10.1016/j.neuroscience.2015.12.040 

  69. Neuron Jiang 78 8 2013 Modeling autism by SHANK gene mutations in mice 10.1016/j.neuron.2013.03.016 

  70. Nat. Neurosci. Jung 21 1218 2018 Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice 10.1038/s41593-018-0208-z 

  71. Nat. Rev. Neurosci. Jung 13 308 2012 Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair 10.1038/nrn3210 

  72. Psychopharmacology Kleijer 231 1037 2014 Neurobiology of autism gene products: towards pathogenesis and drug targets 10.1007/s00213-013-3403-3 

  73. Autophagy Klionsky 12 1 2016 Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 10.1080/15548627.2015.1100356 

  74. Mol. Cell. Neurosci. Kolk 32 200 2006 A unique subpopulation of Tbr1-expressing deep layer neurons in the developing cerebral cortex 10.1016/j.mcn.2005.08.022 

  75. Acta Neurol. Scand. Lawrence 121 99 2010 Parvalbumin-, calbindin-, and calretinin-immunoreactive hippocampal interneuron density in autism 10.1111/j.1600-0404.2009.01234.x 

  76. Nat. Commun. Lee 6 7168 2015 Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation 10.1038/ncomms8168 

  77. Biol. Psychiatry Lee 81 838 2017 Excitation/inhibition imbalance in animal models of autism spectrum disorders 10.1016/j.biopsych.2016.05.011 

  78. Front. Mol. Neurosci. Lee 11 209 2018 Shank2 deletion in parvalbumin neurons leads to moderate hyperactivity, enhanced self-grooming and suppressed seizure susceptibility in mice 10.3389/fnmol.2018.00209 

  79. Nat. Neurosci. Liu 21 659 2018 Tbr1 instructs laminar patterning of retinal ganglion cell dendrites 10.1038/s41593-018-0127-z 

  80. Genome Biol. Love 15 550 2014 Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 10.1101/002832 

  81. EMBO Rep. Marinaro 18 603 2017 MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression 10.15252/embr.201642800 

  82. Eur. J. Med. Genet. McDermott 61 253 2018 The TBR1-related autistic-spectrum-disorder phenotype and its clinical spectrum 10.1016/j.ejmg.2017.12.009 

  83. J. Neurosci. McKenna 31 549 2011 Tbr1 and Fezf2 regulate alternate corticofugal neuronal identities during neocortical development 10.1523/JNEUROSCI.4131-10.2011 

  84. Mol. Cell. Neurosci. Mendez-Gomez 46 108 2011 The T-box brain 1 (Tbr1) transcription factor inhibits astrocyte formation in the olfactory bulb and regulates neural stem cell fate 10.1016/j.mcn.2010.08.011 

  85. Nat. Rev. Neurosci. Monteiro 18 147 2017 SHANK proteins: roles at the synapse and in autism spectrum disorder 10.1038/nrn.2016.183 

  86. Genes Brain Behav. Moy 3 287 2004 Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice 10.1111/j.1601-1848.2004.00076.x 

  87. Genes Brain Behav. Moy 8 129 2009 Social approach in genetically engineered mouse lines relevant to autism 10.1111/j.1601-183x.2008.00452.x 

  88. Nature Muller 389 884 1997 Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor 10.1038/39929 

  89. J. Neuroimmune. Pharmacol. Mulligan 7 774 2012 Wnt signaling in vertebrate neural development and function 10.1007/s11481-012-9404-x 

  90. Nature Neale 485 242 2012 Patterns and rates of exonic de novo mutations in autism spectrum disorders 10.1038/nature11011 

  91. Neuron Nelson 87 684 2015 Excitatory/inhibitory balance and circuit homeostasis in autism spectrum disorders 10.1016/j.neuron.2015.07.033 

  92. Genome Res. Notwell 26 1013 2016 TBR1 regulates autism risk genes in the developing neocortex 10.1101/gr.203612.115 

  93. Nat. Commun. O’Roak 5 5595 2014 Recurrent de novo mutations implicate novel genes underlying simplex autism risk 10.1038/ncomms6595 

  94. Science O’Roak 338 1619 2012 Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders 10.1126/science.1227764 

  95. Dev. Cell Ozhan 26 331 2013 Lypd6 enhances Wnt/β-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains 10.1016/j.devcel.2013.07.020 

  96. Am. J. Med. Genet. A Palumbo 828 2014 TBR1 is the candidate gene for intellectual disability in patients with a 2q24.2 interstitial deletion 10.1002/ajmg.a.36363 

  97. Nat. Methods Patro 14 417 2017 Salmon provides fast and bias-aware quantification of transcript expression 10.1038/nmeth.4197 

  98. Cell Penagarikano 147 235 2011 Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities and core autism-related deficits 10.1016/j.cell.2011.08.040 

  99. Front. Cell. Neurosci. Petrelli 10 21 2016 Astrocytes and microglia and their potential link with autism spectrum disorders 10.3389/fncel.2016.00021 

  100. Neural Plast. Pizzarelli 2011 297153 2011 Alterations of GABAergic signaling in autism spectrum disorders 10.1155/2011/297153 

  101. Curr. Opin. Neurobiol. Portfors 28 115 2014 The role of ultrasonic vocalizations in mouse communication 10.1016/j.conb.2014.07.002 

  102. J. Neurosci. Methods Quinn 130 83 2003 LABORAS: initial pharmacological validation of a system allowing continuous monitoring of laboratory rodent behaviour 10.1016/s0165-0270(03)00227-9 

  103. Nucleic Acids Res. Rodrigues 46 W350 2018 DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability 10.1093/nar/gky300 

  104. Dev. Med. Child Neurol. Rosti 56 12 2014 The genetic landscape of autism spectrum disorders 10.1111/dmcn.12278 

  105. Genes Brain Behav. Rubenstein 2 255 2003 Model of autism: increased ratio of excitation/inhibition in key neural systems 10.1034/j.1601-183x.2003.00037.x 

  106. Sci. Transl. Med. Sakai 3 86ra49 2011 Protein interactome reveals converging molecular pathways among autism disorders 10.1126/scitranslmed.3002166 

  107. Neuron Sanders 87 1215 2015 Insights into autism spectrum disorder genomic architecture and biology from 71 Risk Loci 10.1016/j.neuron.2015.09.016 

  108. Autism Res. Saunders 6 69 2013 Knockout of NMDA receptors in parvalbumin interneurons recreates autism-like phenotypes 10.1002/aur.1264 

  109. Neurosci. Biobehav. Rev. Scattoni 33 508 2009 Ultrasonic vocalizations: a tool for behavioural phenotyping of mouse models of neurodevelopmental disorders 10.1016/j.neubiorev.2008.08.003 

  110. Sci. Transl. Med. Selimbeyoglu 9 eaah6733 2017 Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2-deficient mice 10.1126/scitranslmed.aah6733 

  111. Cell Shigeoka 166 181 2016 Dynamic axonal translation in developing and mature visual circuits 10.1016/j.cell.2016.05.029 

  112. Nat. Rev. Neurosci. Silverman 11 490 2010 Behavioural phenotyping assays for mouse models of autism 10.1038/nrn2851 

  113. Nature Sohal 459 698 2009 Parvalbumin neurons and γ rhythms enhance cortical circuit performance 10.1038/nature07991 

  114. F1000Res. Soneson 4 1521 2015 Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences 10.12688/f1000research.7563.2 

  115. Brain Res. Bull. Song 136 101 2018 Crosstalk between glia, extracellular matrix and neurons 10.1016/j.brainresbull.2017.03.003 

  116. Trends Pharmacol. Sci. Spooren 33 669 2012 Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders 10.1016/j.tips.2012.09.004 

  117. Dev. Neurobiol. Stamatakou 74 818 2014 Postsynaptic assembly: a role for Wnt signaling 10.1002/dneu.22138 

  118. Proc. Natl. Acad. Sci. U S A Subramanian 102 15545 2005 Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles 10.1073/pnas.0506580102 

  119. Nature Sudhof 455 903 2008 Neuroligins and neurexins link synaptic function to cognitive disease 10.1038/nature07456 

  120. Science Tabuchi 318 71 2007 A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice 10.1126/science.1146221 

  121. Nat. Neurosci. Tiberi 15 1627 2012 BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets 10.1038/nn.3264 

  122. Mol. Syndromol. Traylor 3 102 2012 Investigation of TBR1 hemizygosity: four individuals with 2q24 microdeletions 10.1159/000342008 

  123. J. Neurosci. Tsui 33 244 2013 FoxP2 regulates neurogenesis during embryonic cortical development 10.1523/jneurosci.1665-12.2013 

  124. Neuron Tuncdemir 89 521 2016 Early somatostatin interneuron connectivity mediates the maturation of deep layer cortical circuits 10.1016/j.neuron.2015.11.020 

  125. Eur. J. Med. Genet. Vegas 61 759 2018 Mutations in TBR1 gene leads to cortical malformations and intellectual disability 10.1016/j.ejmg.2018.09.012 

  126. FASEB J. Venstrom 7 996 1993 Extracellular matrix. 2: role of extracellular matrix molecules and their receptors in the nervous system 10.1096/fasebj.7.11.8370483 

  127. Cell Walsh 135 396 2008 Autism and brain development 10.1016/j.cell.2008.10.015 

  128. J. Neurochem Wang 91 1483 2004 Identification of Tbr-1/CASK complex target genes in neurons 10.1111/j.1471-4159.2004.02845.x 

  129. Neuron Wang 42 113 2004 Transcriptional modification by a CASK-interacting nucleosome assembly protein 10.1016/s0896-6273(04)00139-4 

  130. Nucleic Acids Res. Waterhouse 46 W296 2018 SWISS-MODEL: homology modelling of protein structures and complexes 10.1093/nar/gky427 

  131. Nat. Commun. Werling 7 10717 2016 Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders 10.1038/ncomms10717 

  132. Dev. Neurobiol. Wlodarczyk 71 1040 2011 Extracellular matrix molecules, their receptors and secreted proteases in synaptic plasticity 10.1002/dneu.20958 

  133. Cell Tissue Res. Wohr 354 81 2013 Affective communication in rodents: ultrasonic vocalizations as a tool for research on emotion and motivation 10.1007/s00441-013-1607-9 

  134. Front. Mol. Neurosci. Won 6 19 2013 Autism spectrum disorder causes, mechanisms and treatments: focus on neuronal synapses 10.3389/fnmol.2013.00019 

  135. Neuroscience Xiao 144 714 2007 Chemotherapy-evoked painful peripheral neuropathy: analgesic effects of gabapentin and effects on expression of the α-2-δ type-1 calcium channel subunit 10.1016/j.neuroscience.2006.09.044 

  136. Nature Yizhar 477 171 2011 Neocortical excitation/inhibition balance in information processing and social dysfunction 10.1038/nature10360 

  137. Front. Cell. Neurosci. Yoo 12 341 2018 GABA neuronal deletion of Shank3 exons 14-16 in mice suppresses striatal excitatory synaptic input and induces social and locomotor abnormalities 10.3389/fncel.2018.00341 

  138. Science Zoghbi 302 826 2003 Postnatal neurodevelopmental disorders: meeting at the synapse? 10.1126/science.1089071 

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