최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Nutrients, v.13 no.11, 2021년, pp.4133 -
Elsaid, Ahmed F. (Department of Community Medicine and Public Health, Zagazig University, Zagazig 44519, Egypt) , Agrawal, Sudhanshu (Division of Basic and Clinical Immunology, Department of Medicine, University of California, Irvine, CA 92697, USA) , Agrawal, Anshu (sagrawal@uci.edu (S.A.)) , Ghoneum, Mamdooh (aagrawal@uci.edu (A.A.))
Influenza-like illness (ILI) remains a major cause of severe mortality and morbidity in the elderly. Aging is associated with a decreased ability to sense pathogens and mount effective innate and adaptive immune responses, thus mandating the development of protective nutraceuticals. Biobran/MGN-3, a...
1. Stohr K. Influenza—WHO cares Lancet Infect. Dis. 2002 2 517 10.1016/S1473-3099(02)00366-3 12206966
2. Lee N. Chan P.K. Lui G.C. Wong B.C. Sin W.W. Choi K.W. Wong R.Y. Lee E.L. Yeung A.C. Ngai K.L. Complications and outcomes of pandemic 2009 Influenza A (H1N1) virus infection in hospitalized adults: How do they differ from those in seasonal influenza? J. Infect. Dis. 2011 203 1739 1747 10.1093/infdis/jir187 21606532
3. Fitzner J. Qasmieh S. Mounts A.W. Alexander B. Besselaar T. Briand S. Brown C. Clark S. Dueger E. Gross D. Revision of clinical case definitions: Influenza-like illness and severe acute respiratory infection Bull. World Health Organ. 2018 96 122 128 10.2471/BLT.17.194514 29403115
4. Kammerer P.E. Montiel S. Kriner P. Bojorquez I. Ramirez V.B. Vazquez-Erlbeck M. Influenza-like illness surveillance on the California–Mexico border, 2004–2009 Influenza Other Respir. Viruses 2012 6 358 366 10.1111/j.1750-2659.2011.00316.x 22212638
5. Bollaerts K. Antoine J. Van Casteren V. Ducoffre G. Hens N. Quoilin S. Contribution of respiratory pathogens to influenza-like illness consultations Epidemiol. Infect. 2013 141 2196 2204 10.1017/S0950268812002506 23217849
6. Fu Y. Pan L. Sun Q. Zhu W. Zhu L. Ye C. Xue C. Wang Y. Liu Q. Ma P. The clinical and etiological characteristics of influenza-like illness (ILI) in outpatients in Shanghai, China, 2011 to 2013 PLoS ONE 2015 10 e0119513 10.1371/journal.pone.0119513 25822885
7. Souty C. Masse S. Valette M. Behillil S. Bonmarin I. Pino C. Baseline characteristics and clinical symptoms related to respiratory viruses identified among patients presenting with influenza-like illness in primary care Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. 2019 25 1147 1153 10.1016/j.cmi.2019.01.014
8. Refaey S. Amin M. Labib M. Kandeel A. Influenza virus positivity and circulating subtypes among cases of influenza-like illness and severe acute respiratory infection, Egypt, 2012–2015 East Mediterr. Health J. 2016 22 527 536 10.26719/2016.22.7.523 27714747
9. Pop-Vicas A. Gravenstein S. Influenza in the elderly: A mini-review Gerontology 2011 57 397 404 10.1159/000319033 20805683
10. Talbot H.K. Influenza in older adults Infect. Dis. Clin. N. Am. 2017 31 757 766 10.1016/j.idc.2017.07.005
11. Takahasi K. Yoneyama M. Nishihori T. Hirai R. Kumeta H. Narita R. Gale M. Jr. Inagaki F. Fujita T. Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses Mol. Cell. 2008 29 428 440 10.1016/j.molcel.2007.11.028 18242112
12. Baum A. Sachidanandam R. Garcia-Sastre A. Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing Proc. Natl. Acad. Sci. USA 2010 108 3092 10.1073/pnas.1005077107
13. Takeuchi O. Akira S. Pattern recognition receptors and inflammation Cell 2010 140 805 820 10.1016/j.cell.2010.01.022 20303872
14. Barral P.M. Sarkar D. Su Z.Z. Barber G.N. DeSalle R. Racaniello V.R. Fisher P.B. Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of innate immunity Pharmacol. Ther. 2009 124 219 234 10.1016/j.pharmthera.2009.06.012 19615405
15. Iwasaki A. Medzhitov R. Regulation of adaptive immunity by the innate immune system Science 2010 327 291 295 10.1126/science.1183021 20075244
16. Schoggins J.W. Rice C.M. Interferon-stimulated genes and their antiviral effector functions Curr. Opin. Virol. 2011 1 519 525 10.1016/j.coviro.2011.10.008 22328912
17. Lindenmann J. Lane C.A. Hobson D. The resistance of A2G mice to myxoviruses J. Immunol. 1963 90 942 951 14050204
18. Lenschow D.J. Lai C. Frias-Staheli N. Giannakopoulos N.V. Lutz A. Wolff T. IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses Proc. Natl. Acad. Sci. USA 2007 104 1371 1376 10.1073/pnas.0607038104 17227866
19. Lai C. Struckhoff J.J. Schneider J. Martinez-Sobrido L. Wolff T. Garcia-Sastre A. Zhang D.E. Lenschow D.J. Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection J. Virol. 2009 83 1147 1151 10.1128/JVI.00105-08 19004958
20. Orange J.S. Human natural killer cell deficiencies and susceptibility to infection Microbes Infect. 2002 4 1545 1558 10.1016/S1286-4579(02)00038-2 12505527
21. Lodoen M.B. Lanier L.L. Natural killer cells as an initial defense against pathogens Curr. Opin. Immunol. 2006 18 391 398 10.1016/j.coi.2006.05.002 16765573
22. Vivier E. Ugolini S. Blaise D. Chabannon C. Brossay L. Targeting natural killer cells and natural killer T cells in cancer Nat. Rev. Immunol. 2012 12 239 252 10.1038/nri3174 22437937
23. Terunuma H. Deng X. Dewan Z. Fujimoto S. Yamamoto N. Potential role of NK cells in the induction of immune responses: Implications for NK cell-based immunotherapy for cancers and viral infections Int. Rev. Immunol. 2008 27 93 110 10.1080/08830180801911743 18437601
24. Cooley S. Burns L.J. Repka T. Miller J.S. Natural killer cell cytotoxicity of breast cancer targets is enhanced by two distinct mechanisms of antibody-dependent cellular cytotoxicity against LFA-3 and HER2/neu Exp. Hematol. 1999 27 1533 1541 10.1016/S0301-472X(99)00089-2 10517495
25. Hammer Q. Romagnani C. About training and memory: NK-cell adaptation to viral infections Adv. Immunol. 2017 133 171 207 28215279
26. Peng H. Tian Z. NK cells in liver homeostasis and viral hepatitis Sci. China Life Sci. 2018 61 1477 1485 10.1007/s11427-018-9407-2 30421296
27. Mikulak J. Oriolo F. Zaghi E. Di Vito C. Mavilio D. Natural killer cells in HIV-1 infection and therapy AIDS 2017 31 2317 2330 10.1097/QAD.0000000000001645 28926399
28. Flórez-Álvarez L. Hernandez J.C. Zapata W. NK cells in HIV-1 infection: From basic science to vaccine strategies Front. Immunol. 2018 9 2290 10.3389/fimmu.2018.02290 30386329
29. Yoo J.K. Kim T.S. Hufford M.M. Braciale T.J. Viral infection of the lung: Host response and sequelae J. Allergy Clin. Immunol. 2013 132 1263 1276 10.1016/j.jaci.2013.06.006 23915713
30. Smyth M.J. Cretney E. Kelly J.M. Westwood J.A. Street S.E. Yagita H. Takeda K. van Dommelen S.L. Degli-Esposti M.A. Hayakawa Y. Activation of NK cell cytotoxicity Mol. Immunol. 2005 42 501 510 10.1016/j.molimm.2004.07.034 15607806
31. Miller J.S. Biology of Natural Killer Cells in Cancer and Infection Cancer Investig. 2002 20 405 419 10.1081/CNV-120001185 12025235
32. Ghoneum M. Suzuki K. Gollapudi S. Phorbol myristate acetate corrects impaired NK function of old mice Scand. J. Immunol. 1991 34 391 397 10.1111/j.1365-3083.1991.tb01562.x 1925408
33. Mariani E. Sgobbi S. Meneghetti A. Tadolini M. Tarozzi A. Sinoppi M. Cattini L. Facchini A. Perforins in human cytolytic cells: The effect of age Mech. Ageing Dev. 1996 92 195 209 10.1016/S0047-6374(96)01829-5 9080399
34. Rukavina D. Laskarin G. Rubesa G. Strbo N. Bedenicki I. Manestar D. Glavas M. Christmas S.E. Podack E.R. Age-related decline of perforin expression in human cytotoxic T lymphocytes and natural killer cells Blood 1998 92 2410 2420 10.1182/blood.V92.7.2410 9746781
35. Ghoneum M. Enhancement of human natural killer cell activity by modified arabinoxylan from rice bran (MGN-3) Int. J. Immunother. 1998 XIV 89 99
36. Ghoneum M. Jewett A. Production of tumor necrosis factor-alpha and interferon-gamma from human peripheral blood lymphocytes by MGN-3, a modified arabinoxylan from rice bran, and its synergy with interleukin-2 in vitro Cancer Detect. Prev. 2000 24 314 324 11059563
37. Cholujova D. Jakubikova J. Czako B. Martisova M. Hunakova L. Duraj J. Mistrik M. Sedlak J. MGN-3 arabinoxylan rice bran modulates innate immunity in multiple myeloma patients Cancer Immunol. Immunother. 2013 62 437 445 10.1007/s00262-012-1344-z 22941038
38. Pérez-Martínez A. Valentín J. Fernández L. Hernández-Jiménez E. López-Collazo E. Arabinoxylan rice bran (MGN-3/Biobran) enhances natural killer cell-mediated cytotoxicity against neuroblastoma in vitro and in vivo Cytotherapy 2015 17 601 612 10.1016/j.jcyt.2014.11.001 25541298
39. Ghoneum M. Abedi S. Enhancement of natural killer cell activity of aged mice by modified arabinoxylan rice bran (MGN-3/Biobran) J. Pharm. Pharmacol. 2004 56 1581 1588 10.1211/0022357044922 15563765
40. Elsaid A.F. Shaheen M. Ghoneum M. Biobran/MGN-3, an arabinoxylan rice bran, enhances NK cell activity in geriatric subjects: A randomized, double blind, placebo-controlled clinical trial Exp. Ther. Med. 2018 15 2313 2320 10.3892/etm.2018.5713 29456638
41. Ghoneum M. Matsuura M. Gollapudi S. Modified arabinoxylan rice bran (MGN3/Biobran) enhances intracellular killing of microbes by human phagocytic cells in vitro Int. J. Immunopathol. Pharmacol. 2008 21 87 95 10.1177/039463200802100110 18336734
42. Ghoneum M. Agrawal S. Activation of human monocyte-derived dendritic cells in vitro by biological response modifier arabinoxylan rice bran (MGN-3/Biobran) Int. J. Immunopathol. Pharmcol. 2011 24 941 948 10.1177/039463201102400412 22230400
43. Ghoneum M. Agrawal S. MGN-3/Biobran enhances generation of cytotoxic CD8+ T cells via upregulation of DEC-205 expression on dendritic cells Int. J. Immunopathol. Pharmacol. 2014 27 523 530 10.1177/039463201402700408 25572732
44. Ghoneum M. Anti-HIV activity in vitro of MGN-3, an activated arabinoxylane from rice bran Biochem. Biophys. Res. Commun. 1998 243 25 29 10.1006/bbrc.1997.8047 9473473
45. Tazawa K. Ichihashi K. Fujii T. Omura K. Anazawa M. Maeda H. The orally administration of the Hydrolysis Rice Bran prevents a common cold syndrome for the elderly people based on immunomodulatory function J. Trad. Med. 2003 20 132 141
46. Salama H. Medhat E. Shaheen M. Zekri A.N. Darwish T. Ghoneum M. Arabinoxylan rice bran (Biobran) suppresses the viremia level in patients with chronic HCV infection: A randomized trial Int. J. Immunopathol. Pharmacol. 2016 29 647 653 10.1177/0394632016674954 27799299
47. Elsaid A.F. Fahmi R.M. Shaheen M. Ghoneum M. The enhancing effects of Biobran/MGN-3, an arabinoxylan rice bran, on healthy old adults’ health-related quality of life: A randomized, double-blind, placebo-controlled clinical trial Qual. Life Res. 2020 29 357 367 10.1007/s11136-019-02286-7 31489525
48. Ghoneum M. Brown J. NK immunorestoration of cancer patients by MGN-3, a modified arabinoxylan rice bran (study of 32 patients followed for up to 4 years) Anti-Aging Med. Ther. 1999 3 217 226
49. Takahara K. Sano K. The life prolongation and QOL improvement effect of rice bran arabinoxylan derivative (MGN-3. Bio-Bran) for progressive cancer Clin. Pharmacol. Ther. 2004 14 267 271
50. World Health Organization Proposed Working Definition of an Older Person in Africa for the MDS Project Available online: http://www.who.int/healthinfo/survey/ageingdefnolder/en/index.html (accessed on 6 May 2020)
51. Centers for Disease Control and Prevention Principles of Epidemiology in Public Health Practice, Third Edition. An Introduction to Applied Epidemiology and Biostatistics. Lesson 3: Measures of Risk; Section 2: Morbidity Frequency Measures Available online: https://www.cdc.gov/csels/dsepd/ss1978/lesson3/section2.html (accessed on 3 September 2020)
52. Alter G. Malenfant J.M. Altfeld M. CD107a as a functional marker for the identification of natural killer cell activity J. Immunol. Methods 2004 294 15 22 10.1016/j.jim.2004.08.008 15604012
53. Dean A.G. Sullivan K.M. Soe M.M. OpenEpi: Open Source Epidemiologic Statistics for Public Health, Version 3.01 Available online: www.OpenEpi.com (accessed on 29 January 2014)
54. Corp IBM IBM SPSS Statistics for Windows, Version 20 IBM Corp. Armonk, NY, USA 2010
55. Tazawa K. BioBran/MGN-3 (Rice Bran Arabinoxylan Deritive): Basic and Clinical Application to Integrative Medicine Iyakushuppan Co., Publishers Tokyo, Japan 2006 18 22
56. Daiwa Pharmaceutical Co., Ltd. BioBran Available online: https://www.daiwa-pharm.com/english/product/biobran.html (accessed on 10 November 2020)
57. Laue C. Stevens Y. van Erp M. Papazova E. Soeth E. Pannenbeckers A. Stolte E. Böhm R. Gall S.L. Falourd X. Adjuvant Effect of Orally Applied Preparations Containing Non-Digestible Polysaccharides on Influenza Vaccination in Healthy Seniors: A Double-Blind, Randomised, Controlled Pilot Trial Nutrients 2021 13 2683 10.3390/nu13082683 34444843
58. Boudreau J.E. Hsu K.C. Natural killer cell education in human health and disease Curr. Opin. Immunol. 2018 50 102 111 10.1016/j.coi.2017.11.003 29413815
59. Li J. Li H. Mao H. Yu M. Yang F. Feng T. Fan Y. Lu Q. Shen C. Yin Z. Impaired NK cell antiviral cytokine response against influenza virus in small-for-gestational-age neonates Cell. Mol. Immunol. 2013 10 437 443 10.1038/cmi.2013.31 23872919
60. Sun C. Sun H.Y. Xiao W.H. Zhang C. Tian Z.G. Natural killer cell dysfunction in hepatocellular carcinoma and NK cell-based immunotherapy Acta Pharmacol. Sin. 2015 36 1191 1199 10.1038/aps.2015.41 26073325
61. Orange J.S. Natural killer cell deficiency J. Allergy Clin. Immunol. 2013 132 515 525 10.1016/j.jaci.2013.07.020 23993353
62. Loo Y.M. Gale M. Jr. Immune signaling by RIG-I-like receptors Immunity 2011 34 680 692 10.1016/j.immuni.2011.05.003 21616437
63. Gitlin L. Barchet W. Gilfillan S. Cella M. Beutler B. Flavell R.A. Diamond M.S. Colonna M. Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus Proc. Natl. Acad. Sci. USA 2006 103 8459 8464 10.1073/pnas.0603082103 16714379
64. van Kasteren P.B. Beugeling C. Ninaber D.K. Frias-Staheli N. van Boheemen S. Garcia-Sastre A. Snijder E.J. Kikkert M. Arterivirus and nairovirus ovarian tumor domaincontaining deubiquitinases target activated RIG-I to control innate immune signaling J. Virol. 2012 86 773 785 10.1128/JVI.06277-11 22072774
65. Zhao Y. Ye X. Dunker W. Song Y. Karijolich J. RIG-I like receptor sensing of host RNAs facilitates the cell-intrinsic immune response to KSHV infection Nat. Commun. 2018 9 4841 10.1038/s41467-018-07314-7 30451863
66. Zhang Z. Filzmayer C. Ni Y. Sültmann H. Mutz P. Hiet M.-S. Vondran F.W. Bartenschlager R. Urban S. Hepatitis D virus replication is sensed by MDA5 and induces IFN-b/l responses in hepatocytes J. Hepatol. 2018 69 25 35 10.1016/j.jhep.2018.02.021 29524530
67. Morales D.J. Lenschow D.J. The antiviral activities of ISG15 J. Mol. Biol. 2013 425 4995 5008 10.1016/j.jmb.2013.09.041 24095857
68. Yamada T. Sato S. Sotoyama Y. Orba Y. Sawa H. Yamauchi H. Sasaki M. Takaoka A. RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells Nat. Immunol. 2021 22 820 828 10.1038/s41590-021-00942-0 33976430
69. Sampaio N.G. Chauveau L. Hertzog J. Bridgeman A. Fowler G. Moonen J.P. Dupont M. Russell R.A. Noerenberg M. Rehwinkel J. The RNA sensor MDA5 detects SARS-CoV-2 infection bioRxiv 2021 10.1038/s41598-021-92940-3 34211037
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
오픈액세스 학술지에 출판된 논문
※ AI-Helper는 부적절한 답변을 할 수 있습니다.