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Insulin-Like Growth Factor-I Augments Chondrocyte Hypertrophy and Reverses Glucocorticoid-Mediated Growth Retardation in Fetal Mice Metatarsal Cultures 원문보기

Endocrinology, v.145 no.5, 2004년, pp.2478 - 2486  

Mushtaq, T. (Bone and Endocrine Research Group (T.M., S.F.A.), Royal Hospital for Sick Children, Glasgow G3 8SJ) ,  Bijman, P. (Bone Biology Group (T.M., P.B., C.F.), Roslin Institute, Edinburgh EH25 9PS, United Kingdom) ,  Ahmed, S. F. (Bone and Endocrine Research Group (T.M., S.F.A.), Royal Hospital for Sick Children, Glasgow G3 8SJ) ,  Farquharson, C. (Bone Biology Group (T.M., P.B., C.F.), Roslin Institute, Edinburgh EH25 9PS, United Kingdom)

Abstract AI-Helper 아이콘AI-Helper

AbstractThe study aims were to improve our understanding of the mechanisms of glucocorticoid-induced growth retardation at the growth plate and determine whether IGF-I could ameliorate the effects. Fetal mouse metatarsals were cultured for up to 10 d with dexamethasone (Dex; 10-6m) and/or IGF-I and ...

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