Sclerotic fibroma is an uncommom fibrotic neoplasm that can occur as solitary lesions in otherwise healthy individuals. Multiple sclerotic fibromas of the skin are considered a cutaneous marker of multiple hamartoma syndrome or Cowden's disease. Sclerotic fibroma was first described by Weary et al. in the tongue of a patient with Cowden's disease in 1972. Rapini and Golitz described the sporadic occurrence of histologically identical tumors, and they suggested the names `hypocellular fibroma' and `sclerotic fibromas of the skin' for these lesions in 1990. The characteristics of sclerotic fibromas include hypocellularity and stromal sclerosis with eosinophilic, hyalinized collagen bundles in a parallel or whorled arrangement. We report two cases of solitary sclerotic fibroma of the skin not associated with Cowden's disease.
DOI 인용 스타일