We report a patient suffering from Marie Unna's hypotrichosis. A 24-year-old man presented with a progressive hair loss. Since puberty, he had experienced a loss of hair on the scalp, eyebrow and eyelash, and the hair was coarse and twisted. On physical examination and laboratory studies, there were no associated abnormalities in the patient. The scanning electron microscopic examination of the affected hair demonstrated cuticular peeling, and twisting or angulation of hair shaft, which showed the typical clinical manifestations of Marie Unna's hypotrichosis.
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