Autoimmune progesterone dermatitis is a rare cyclic premenstrual reaction to a variety of progesterone produced during the luteal phase of a woman's menstrual cycle, including urticaria, urticarial papule, papulovesicle, eczematous lesion, erythema multiforme, and progesterone-induced anaphylaxis. A 23-year-old woman presented with brown colored hyperpigmented reticular patches on the chest and abdomen. Since the age of 20, she had been recurrently suffering from pruritic eruption that appeared regularly 5 to 10 days prior to menstruation and persisted for several days. Intradermal skin test reaction to progesterone was positive. These features were consistent with the diagnosis of autoimmune progesterone dermatitis.
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