Congenital self-healing reticulohistiocytosis is a variant of Langerhans cell histiocytosis, and shows spontaneous resolution within 3-4 months. Histopathologically, it is characterized by epidermotropic infiltrates of histiocytes with kidney-shaped nuclei and abundant eosinophilic cytoplasm. We present a female new-born baby with congenital, multiple, erythematous papules containing some vesicles. A skin biopsy showed typical features of Langerhans cell histiocytosis. Her skin lesion is healed spontaneously within 2 months, without scarring.
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