Herpes zoster is characterized by unilateral grouped vesicles along the distribution of a single spinal or cranial sensory nerves. Recurrent herpes zoster is rare and may be associated with severe immunocompromised state. Human immunodeficiency virus (HIV) infection is associated with an increased incidence of zoster, which tends to be severe, presumably due to HIV-induced depression of cellular immunity. We report a case of a 43-year-old male who was presented with recurrent herpes zoster and was not responded to antiviral treatment (famciclovir 750mg/day) for 14days. We checked his immunologic status and found to be decreased T4 count and infected HIV.
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