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Interleukin‐1β (IL‐1β) inhibition: a possible mechanism for the anti‐inflammatory potency of liposomally conjugated methotrexate formulations in arthritis 원문보기

British journal of pharmacology : BJP, v.128 no.1, 1999년, pp.234 - 240  

Williams, A S ,  Jones, S G ,  Goodfellow, R M ,  Amos, N ,  Williams, B D

Abstract AI-Helper 아이콘AI-Helper

Liposomes with conventional and long‐circulation times were employed as carriers for the methotrexate derivative MTX‐γ‐DMPE (MTX‐EPC and MTX‐PEG respectively), their mechanism of action was investigated in vitro and in vivo and their therapeutic efficacy asse...

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