[논문]Inhibitory effects of quercetin 3-rhamnoside on influenza A virus replication

Choi, H.J.; Song, J.H.; Park, K.S.; Kwon, D.H.

doi:10.1016/j.ejps.2009.03.002

Inhibitory effects of quercetin 3-rhamnoside on influenza A virus replication

European journal of pharmaceutical sciences, v.37 no.3/4, 2009년, pp.329 - 333

Choi, H.J. (Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-333, Republic of Korea) , Song, J.H. , Park, K.S. , Kwon, D.H.

Abstract ▼ AI-Helper

Influenza viruses cause significant morbidity and mortality in humans through epidemics or pandemics. The lack of effective therapeutical treatment underlines the importance of research for new antiviral compounds. Flavonoids widely exist in the plant kingdom, and their antiviral activities against various viruses have been recently reported. In this study, the anti-influenza A/WS/33 virus of quercetin 3-rhamnoside (Q3R) from Houttuynia cordata was evaluated using a cytopathic effect (CPE) reduction method, the assay results demonstrated that Q3R possessed strong anti-influenza A/WS/33 virus reducing the formation of a visible CPE. Q3R also did inhibit virus replication in the initial stage of virus infection by indirect interaction with virus particles. However, oseltamivir has relative weaker efficacy compared to Q3R. Therefore, these findings provide important information for the utilization of Q3R for influenza treatment.

주제어

참고문헌 (26)

Nat. Prod. Res. Amaral 19 2 157 2005 10.1080/14786410410001704778 Phenolic profile of hazelnut (Corylus avellana L.) leaves cultivars grown in Portugal

상세보기
Antivir. Res. Chang 9 163 1988 10.1016/0166-3542(88)90001-0 Inhibition of growth of human immunodeficiency virus in vitro by crude extracts of Chinese medicinal herbs

상세보기
Am. J. Chin. Med. Chiang 31 355 2003 10.1142/S0192415X03001090 Anti-herpes simplex virus activity of Bidens pilosa and Houttuynia cordata

상세보기
J. Antimicrob. Chemother. Chiang 52 194 2003 10.1093/jac/dkg291 In vitro antiviral activities of Caesalpinia pulcherrima and its related flavonoids

상세보기
Antivir. Res. Choi 81 77 2008 10.1016/j.antiviral.2008.10.002 Antiviral activity of quercetin 7-rhamnoside against porcine epidemic diarrhea virus

상세보기
Anal. Biochem. Chomczynski 162 156 1987 10.1016/0003-2697(87)90021-2 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

상세보기
Antivir. Res. Deyde 81 16 2009 10.1016/j.antiviral.2008.08.008 Pyrosequencing as a tool to detect molecular markers of resistance to neuraminidase inhibitors in seasonal influenza A viruses

상세보기
Curr. Drug Targets Garman 5 119 2004 10.2174/1389450043490604 Controlling influenza by inhibiting the virus's neuraminidase

상세보기
Pharmacol. Ther. Havsteen 96 67 2002 10.1016/S0163-7258(02)00298-X The biochemistry and medical significance of the flavonoids

상세보기
Planta Med. Hayashi 61 237 1995 10.1055/s-2006-958063 Virucidal effects of the steam distillate from Houttuynia cordata and its components on HV-1, influenza virus, and HIV

상세보기
Lancet Hertog 342 1007 1993 10.1016/0140-6736(93)92876-U Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

상세보기
J. Appl. Microbiol. Jassim 95 412 2003 10.1046/j.1365-2672.2003.02026.x Novel antiviral agents: a medicinal plant perspective

상세보기
Cancer Lett. Koyama 263 61 2008 10.1016/j.canlet.2007.12.016 Correlation between oxidation potentials and inhibitory effects on Epstein-Barr virus activation of flavonoids

상세보기
J. Ethnopharmacol. Lau 118 79 2008 10.1016/j.jep.2008.03.018 Immunomodulatory and anti-SARS activities of Houttuynia cordata

상세보기
Lancet Lee 337 1197 1991 10.1016/0140-6736(91)92867-2 Dietary effects on breast-cancer risk in Singapore

상세보기
Biol. Pharm. Bull. Li 31 743 2008 10.1248/bpb.31.743 Anti-hepatitis B virus activities of Geranium carolinianum L. extracts and identification of the active components

상세보기
Planta Med. Liu 74 847 2008 10.1055/s-2008-1074558 Anti-influenza virus activities of flavonoids from the medicinal plant Elsholtzia rugulosa

상세보기
Phytochemistry Manguro 64 4 891 2003 10.1016/S0031-9422(03)00374-1 Flavonol glycosides of Warburgia ugandensis leaves

상세보기
Bioorg. Med. Chem. Lett. Mori 18 4249 2008 10.1016/j.bmcl.2008.02.020 Enhanced anti-influenza A virus activity of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives: effect of alkyl chain length

상세보기
Experientia Mucsi 41 930 1985 10.1007/BF01970018 Inhibition of virus multiplication and alteration of cyclic AMP level in cell cultures by flavonoids

상세보기
Hepatology Nahmias 47 1437 2008 10.1002/hep.22197 Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin

상세보기
J. Infect. Dis. Ong 196 181 2007 10.1086/518939 John F. Enders lecture 2006: antivirals for influenza

상세보기
Nat. Med. Palese 10 S82 2004 10.1038/nm1141 Influenza: old and new threats

상세보기
Palese 1647 2007 Fields Virology Orthomyxoviridae: the viruses and their replication
Am. J. Clin. Nutr. Potter 68 1375S 1998 10.1093/ajcn/68.6.1375S Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women

상세보기
Antimicrob. Agents Chemother. Sheu 52 3284 2008 10.1128/AAC.00555-08 Surveillance for neuraminidase inhibitor resistance among human influenza A and B viruses circulating worldwide from 2004-2008

상세보기

LOADING...

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Inhibitory effects of quercetin 3-rhamnoside on influenza A virus replication

Abstract ▼ AI-Helper

주제어

참고문헌 (26)

이 논문을 인용한 문헌

연구과제 타임라인

관련 콘텐츠

원문 URL 링크

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

Inhibitory effects of quercetin 3-rhamnoside on influenza A virus replication

Abstract ▼ AI-Helper

주제어

참고문헌 (26)

이 논문을 인용한 문헌

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

관련 콘텐츠

원문 URL 링크

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트