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Protein engineering of conger eel galectins by tracing of molecular evolution using probable ancestral mutants 원문보기

BMC evolutionary biology, v.10, 2010년, pp.43 - 43  

Konno, Ayumu (Department of Biomolecular Science, Graduate School of Life Sciences, Tohoku University, Sendai 981-8555, Japan) ,  Yonemaru, Shintarou (Department of Biomolecular Science, Graduate School of Life Sciences, Tohoku University, Sendai 981-8555, Japan) ,  Kitagawa, Atsushi (Nagahama Institute of Bio-Science and Technology and Japan Science and Technology Agency, BioInfomatic Research Division, Nagahama, Shiga 526-0829, Japan) ,  Muramoto, Koji (Department of Biomolecular Science, Graduate School of Life Sciences, Tohoku University, Sendai 981-8555, Japan) ,  Shirai, Tsuyoshi (Nagahama Institute of Bio-Science and Technology and Japan Science and Technology Agency, BioInfomatic Research Division, Nagahama, Shiga 526-0829, Japan) ,  Ogawa, Tomohisa (Department of Biomolecular Science, Graduate School of Life Sciences, Tohoku University, Sendai 981-8555, Japan)

Abstract AI-Helper 아이콘AI-Helper

BackgroundConger eel galectins, congerin I (ConI) and congerin II (ConII), show the different molecular characteristics resulting from accelerating evolution. We recently reconstructed a probable ancestral form of congerins, Con-anc. It showed properties similar to those of ConII in terms of thermos...

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