최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, v.81 no.2, 2012년, pp.386 - 391
Graphical abstractThe opposing effects of the co-solvent PEG-400 in a solubility-enabling formulation on carbamazepine apparent solubility and permeability; this solubility-permeability tradeoff may govern the overall in vivo performance of the formulation, and hence should not be overlooked. Abstra...
Pharmaceutical Research Amidon 12 413 1995 10.1023/A:1016212804288 A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability
AAPS Journal Dahan 11 740 2009 10.1208/s12248-009-9144-x Prediction of solubility and permeability class membership: provisional BCS classification of the world’s top oral drugs
European Journal of Pharmaceutics and Biopharmaceutics Lobenberg 50 3 2000 10.1016/S0939-6411(00)00091-6 Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards
Journal of Clinical Pharmacology Martinez 42 620 2002 10.1177/00970002042006005 A mechanistic approach to understanding the factors affecting drug absorption: a review of fundamentals
Journal of Controlled Release Dahan 129 1 2008 10.1016/j.jconrel.2008.03.021 Rationalizing the selection of oral lipid based drug delivery systems by an in vitro dynamic lipolysis model for improved oral bioavailability of poorly water soluble drugs
Advanced Drug Delivery Reviews Lipinski 46 3 2001 10.1016/S0169-409X(00)00129-0 Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
Journal of Pharmaceutical Sciences Dahan 99 2739 2010 10.1002/jps.22033 The solubility-permeability interplay in using cyclodextrins as pharmaceutical solubilizers: mechanistic modeling and application to progesterone
Molecular Pharmaceutics Miller 8 1848 2011 10.1021/mp200181v The solubility-permeability interplay: Mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeation
European Journal of Pharmaceutics and Biopharmaceutics Dahan 67 96 2007 10.1016/j.ejpb.2007.01.017 The effect of different lipid based formulations on the oral absorption of lipophilic drugs: the ability of in vitro lipolysis and consecutive ex vivo intestinal permeability data to predict in vivo bioavailability in rats
Journal of Pharmaceutical Sciences Amidon 71 77 1982 10.1002/jps.2600710120 Theoretical and experimental studies of transport of micelle-solubilized solutes
Journal of Pharmaceutical Sciences Mudra 99 1016 2010 10.1002/jps.21836 Absorption barriers in the rat intestinal mucosa. 3: Effects of polyethoxylated solubilizing agents on drug permeation and metabolism
European Journal of Pharmaceutical Sciences Rege 16 237 2002 10.1016/S0928-0987(02)00055-6 Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers
Journal of Pharmaceutical Sciences Yano 99 1336 2010 10.1002/jps.21919 Mechanisms of membrane transport of poorly soluble drugs: role of micelles in oral absorption processes
Molecular Pharmaceutics Gao 7 1516 2010 10.1021/mp100157s A pH-dilution method for estimation of biorelevant drug solubility along the gastrointestinal tract: application to physiologically based pharmacokinetic modeling
Journal of Pharmaceutical Sciences Crison 85 1005 1996 10.1021/js930336p Drug dissolution into micellar solutions: development of a convective diffusion model and comparison to the film equilibrium model with application to surfactant-facilitated dissolution of carbamazepine
Levich 1962 Physico-Chemical Hydrodynamics
Journal of Controlled Release Miller 137 31 2009 10.1016/j.jconrel.2009.02.018 Quasi-equilibrium analysis of the ion-pair mediated membrane transport of low-permeability drugs
Journal of Medicinal Chemistry Wohnsland 44 923 2001 10.1021/jm001020e High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes
American Journal of Physiology - Gastrointestinal and Liver Physiology Dahan 297 G371 2009 10.1152/ajpgi.00102.2009 Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting
Molecular Pharmaceutics Dahan 6 19 2009 10.1021/mp800088f Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs
Molecular Pharmaceutics Dahan 7 1827 2010 10.1021/mp100175a High-permeability criterion for BCS classification: segmental/pH dependent permeability considerations
Pharmaceutical Research Dahan 26 883 2009 10.1007/s11095-008-9789-7 Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of P-glycoprotein
Journal of Pharmaceutical Sciences Lennernas 87 403 1998 10.1021/js970332a Human intestinal permeability
International Journal of Pharmaceutics Komiya 4 249 1980 10.1016/0378-5173(80)90140-4 Quantitative mechanistic studies in simultaneous fluid flow and intestinal absorption using steroids as model solutes
Molecular Pharmaceutics Miller 2012 10.1021/mp200460u The solubility-permeability interplay when using cosolvents for solubilization: Revising the way we use solubility-enabling formulations
European Journal of Pharmaceutical Sciences Fagerholm 3 247 1995 10.1016/0928-0987(95)00027-B Experimental estimation of the effective unstirred water layer thickness in the human jejunum, and its importance in oral drug absorption
Journal of Pharmacy and Pharmacology Lennernas 49 627 1997 10.1111/j.2042-7158.1997.tb06084.x Human jejunal effective permeability and its correlation with preclinical drug absorption models
Pharmaceutical Research Lennernas 9 1243 1992 10.1023/A:1015888813741 Regional jejunal perfusion, a new in vivo approach to study oral drug absorption in man
Pharmaceutical Research Elmquist 5 Suppl. S217 1988 Physiological modelling of the dependence of renal clearance on urine flow: carbamazepine and two metabolites in man
Pharmaceutical Research Riad 8 491 1991 10.1023/A:1015803312233 Effect of polyethylene glycol 400 on the intestinal permeability of carbamazepine in the rabbit
AAPS Journal Dahan 2012 10.1208/s12248-012-9337-6 The solubility-permeability interplay and its implications in formulation design and development for poorly soluble drugs
International Journal of Pharmaceutics Miller 2012 10.1016/j.ijpharm.2012.03.017 Predicting the solubility-permeability interplay when using cyclodextrins in solubility-enabling formulations: Model validation
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.