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Accounting for the solubility–permeability interplay in oral formulation development for poor water solubility drugs: The effect of PEG-400 on carbamazepine absorption

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, v.81 no.2, 2012년, pp.386 - 391  

Abstract AI-Helper 아이콘AI-Helper

Graphical abstractThe opposing effects of the co-solvent PEG-400 in a solubility-enabling formulation on carbamazepine apparent solubility and permeability; this solubility-permeability tradeoff may govern the overall in vivo performance of the formulation, and hence should not be overlooked. Abstra...

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참고문헌 (32)

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