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NTIS 바로가기Journal of controlled release : official journal of the Controlled Release Society, v.161 no.2, 2012년, pp.645 - 655
van der Maaden, K. (Division of Drug Delivery Technology, Leiden) , Jiskoot, W. , Bouwstra, J.
Microneedles have been used for the dermal and transdermal delivery of a broad range of drugs, such as small molecular weight drugs, oligonucleotides, DNA, peptides, proteins and inactivated viruses. However, until now there are no microneedle-based (trans)dermal drug delivery systems on...
J. Microelectromech. Syst. Gardeniers 12 3 855 2003 10.1109/JMEMS.2003.820293 Silicon micromachined hollow microneedles for transdermal liquid transport
Lab Chip Chin 7 41 2007 10.1039/B611455E Lab-on-a-chip devices for global health: past studies and future opportunities
Anal. Bioanal. Chem. Gardeniers 378 1700 2004 10.1007/s00216-003-2435-7 Lab-on-a-chip systems for biomedical and environmental monitoring
Biomed. Microdevices Tsuchiya 7 4 347 2005 10.1007/s10544-005-6077-8 Development of blood extraction system for health monitoring system
Diabetes Technol. Ther. Vesper 8 1 76 2006 10.1089/dia.2006.8.76 Assessment of trueness of a glucose monitor using interstitial fluid and whole blood as specimen matrix
Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. Huzil 2011 Drug delivery through the skin: molecular simulations of barrier lipids to design more effective noninvasive dermal and transdermal delivery systems for small molecules, biologics, and cosmetics
Biochim. Biophys. Acta Bouwstra 1758 2080 2006 10.1016/j.bbamem.2006.06.021 The skin barrier in healthy and diseased state
Eur. J. Dermatol. Kanitakis 12 4 390 2002 Anatomy, histology and immunohistochemistry of normal human skin
Marieb 2004 Human Anatomy & Physiology
J. Control. Release Bal 148 3 266 2010 10.1016/j.jconrel.2010.09.018 Advances in transcutaneous vaccine delivery: do all ways lead to Rome?
Comp. Immunol. Microbiol. Infect. Dis. Combadiere 31 2-3 293 2008 10.1016/j.cimid.2007.07.015 Particle-based vaccines for transcutaneous vaccination
Immunol. Lett. Warger 109 7 13 2007 10.1016/j.imlet.2007.01.007 Initiation of adaptive immune responses by transcutaneous immunization
Annu. Rev. Biomed. Eng. McAllister 02 289 2000 10.1146/annurev.bioeng.2.1.289 Microfabricated microneedles for gene and drug delivery
Adv. Drug Deliv. Rev. Prausnitz 56 5 581 2004 10.1016/j.addr.2003.10.023 Microneedles for transdermal drug delivery
Nat. Biotechnol. Prausnitz 26 11 1261 2008 10.1038/nbt.1504 Transdermal drug delivery
Skin Res. Technol. Tanner 14 3 249 2008 10.1111/j.1600-0846.2008.00316.x Delivering drugs by the transdermal route: review and comment
Am. J. Health Syst. Pharm. Ball 65 14 1337 2008 10.2146/ajhp070554 Optimizing transdermal drug therapy
Chopda
J. Pharm. Sci. Henry 87 8 922 1998 10.1021/js980042+ Microfabricated microneedles: a novel approach to transdermal drug delivery
Diabetes Technol. Ther. Smart 2 4 549 2000 10.1089/15209150050501961 The use of silicon microfabrication technology in painless blood glucose monitoring
Proc. IEEE Reed 92 1 56 2004 10.1109/JPROC.2003.820542 Microsystems for drug and gene delivery
Biomed. Microdevices Zahn 7 1 59 2005 10.1007/s10544-005-6173-9 Microdialysis microneedles for continuous medical monitoring
Sens. Actuators A Phys. Mukerjee 114 2-3 267 2004 10.1016/j.sna.2003.11.008 Microneedle array for transdermal biological fluid extraction and in situ analysis
J. Microelectromech. Sys. Luttge 16 4 872 2007 10.1109/JMEMS.2007.899339 Integrated lithographic molding for microneedle-based devices
Sens. Actuators B Rodriguez 109 135 2005 10.1016/j.snb.2005.03.015 Fabrication of silicon oxide microneedles from macroporous silicon
Prausnitz 295 2008 Modified Release Drug Delivery, Vol. 2nd ed
Expert Opin. Drug Deliv. Banga 6 4 343 2009 10.1517/17425240902841935 Microporation applications for enhancing drug delivery
Int. J. Pharm. Arora 364 2 227 2008 10.1016/j.ijpharm.2008.08.032 Micro-scale devices for transdermal drug delivery
Biomed. Microdevices Miyano 7 3 185 2005 10.1007/s10544-005-3024-7 Sugar micro needles as transdermic drug delivery system
IEEE Trans. Biomed. Eng. Davis 52 909 2005 10.1109/TBME.2005.845240 Hollow metal microneedles for insulin delivery to diabetic rats
J. Control. Release Park 104 1 51 2005 10.1016/j.jconrel.2005.02.002 Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug delivery
J. Drug Target. Ito 14 5 255 2006 10.1080/10611860600785080 Self-dissolving microneedles for the percutaneous absorption of EPO in mice
Pharm. Res. Park 23 5 1008 2006 10.1007/s11095-006-0028-9 Polymer microneedles for controlled-release drug delivery
J. Sci. Eng. Kuo 7 2 95 2004 A novel polymer microneedle arrays and pdms micromolding technique, Tamkang
AAPS J. Kalluri 2011 10.1208/s12248-011-9288-3 Characterization of Microchannels Created by Metal Microneedles: Formation and Closure
Pharm. Res. Matriano 19 1 63 2002 10.1023/A:1013607400040 Macroflux microprojection array patch technology: a new and efficient approach for intracutaneous immunization
Br. J. Dermatol. Chabri 150 869 2004 10.1111/j.1365-2133.2004.05921.x Microfabricated silicon microneedles for nonviral cutaneous gene delivery
Pharm. Res. Martanto 23 1 104 2006 10.1007/s11095-005-8498-8 Microinfusion using hollow microneedles
Sens. Actuators A Phys. Paik 2004 276 2004 10.1016/j.sna.2003.12.029 In-plane single-crystal-silicon microneedles for minimally invasive microfluid systems
Proc. Natl. Acad. Sci. U. S. A. McAllister 100 24 13755 2003 10.1073/pnas.2331316100 Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies
Stoeber 2002 Presented at the Solid-State Sensor, Actuator and Microsystems Workshop, Hilton Head, SC, 2002 Design, fabrication and testing of a MEMS syringe
Expert Opin. Drug Deliv. Sivamani 4 1 19 2007 10.1517/17425247.4.1.19 Microneedles and transdermal applications
J. Control. Release Cormier 97 503 2004 10.1016/S0168-3659(04)00171-3 Transdermal delivery of desmopressin using a coated microneedle array patch system
Vaccine Widera 24 1653 2006 10.1016/j.vaccine.2005.09.049 Effect of delivery parameters on immunization to ovalbumin following intracutaneous administration by a coated microneedle array patch system
J. Control. Release Verbaan 117 238 2007 10.1016/j.jconrel.2006.11.009 Assembled microneedle arrays enhance the transport of compounds varying over a large range of molecular weight across human dermatomed skin
J. Control. Release Verbaan 128 80 2008 10.1016/j.jconrel.2008.02.009 Improved piercing of microneedle arrays in dermatomed human skin by an impact insertion method
Pharm. Res. Harvey 28 107-116 2011 Microneedle-based intradermal delivery enables rapid lymphatic uptake and distribution of protein drugs
E.M. Nadgorny, J. Drelich, Laser-Based Deposition Technique: Patterning Nanoparticles into Microstructures, Dekker Encyclopedia of Nanoscience and Nanotechnology (2004) 1565-1579.
Pharm. Res. Migalska 28 1919 2011 10.1007/s11095-011-0419-4 Laser-engineered dissolving microneedle arrays for transdermal macromolecular drug delivery
Biomaterials Lee 29 2113 2008 10.1016/j.biomaterials.2007.12.048 Dissolving microneedles for transdermal drug delivery
J. Pharm. Sci. Chu 99 10 4228 2010 10.1002/jps.22140 Fabrication of dissolving polymer microneedles for controlled drug encapsulation and delivery: bubble and pedestal microneedle designs
Nat. Med. Sullivan 16 8 915 2010 10.1038/nm.2182 Dissolving polymer microneedle patches for influenza vaccination
Pharm. Res. Fukushima 28 7 2011 10.1007/s11095-010-0097-7 Two-layered dissolving microneedles for percutaneous delivery of peptide/protein drugs in rats
Biomaterials Lee 32 3134 2011 10.1016/j.biomaterials.2011.01.014 Dissolving microneedles for transdermal drug administration prepared by stepwise controlled drawing of maltose
Biomed. Microdevices Haq 11 1 35 2009 10.1007/s10544-008-9208-1 Clinical administration of microneedles: skin puncture, pain and sensation
J. Invest. Dermatol. Wang 126 5 1080 2006 10.1038/sj.jid.5700150 Precise microinjection into skin using hollow microneedles
Drug Delivery Donnelly 17 4 187 2010 10.3109/10717541003667798 Microneedle-based drug delivery systems: microfabrication, drug delivery, and safety
Microfluid. Nanofluid. Bodhale 8 3 373 2010 10.1007/s10404-009-0467-9 Structural and microfluidic analysis of hollow side-open polymeric microneedles for transdermal drug delivery applications
Mater. Sci. Eng. B Teo 132 151 2006 10.1016/j.mseb.2006.02.008 Transdermal microneedles for drug delivery applications
J. Biomech. Davis 37 1155 2004 10.1016/j.jbiomech.2003.12.010 Insertion of microneedles into skin: measurement and prediction of insertion force and needle fracture force
Biomed. Microdevices Zahn 2 4 295 2000 10.1023/A:1009907306184 Microfabricated polysilicon microneedles for minimally invasive biomedical devices
Biomed. Microdevices Choi 12 2 263 2010 10.1007/s10544-009-9381-x An electrically active microneedle array for electroporation
Biomed. Microdevices Yang 6 3 177 2004 10.1023/B:BMMD.0000042046.07678.2e Microneedle insertion force reduction using vibratory actuation
Biomaterials Crichton 31 4562 2010 10.1016/j.biomaterials.2010.02.022 The effect of strain rate on the precision of penetration of short densely-packed microprojection array patches coated with vaccine
J. Control. Release Chen 152 349 2011 10.1016/j.jconrel.2011.02.026 Improving the reach of vaccines to low-resource regions, with a needle-free vaccine delivery device and long-term thermostabilization
J. Control. Release Bal 35 193 2008 In vivo assessment of safety of microneedle arrays in human skin
IEEE Trans. Biomed. Eng. Roxhed 55 3 1063 2008 10.1109/TBME.2007.906492 Painless drug delivery through microneedle-based transdermal patches featuring active infusion
Chandrasekaran 363 2002 IEEE The Sixteenth Annual International Conference on Micro Electro Mechanical Systems, 2003. MEMS-03 Kyoto Mechanical characterization of surface micromachined hollow metallic microneedles
Microfluid. Nanofluid. Cui 3 377 2007 10.1007/s10404-006-0137-0 Study on a piezoelectric micropump for the controlled drug delivery system
Tucker
Br. J. Dermatol. Li 153 2 404 2005 10.1111/j.1365-2133.2005.06741.x Cutaneous side-effects of transdermal iontophoresis with and without surfactant pretreatment: a single-blinded, randomized controlled trial
Pharm. Res. Kalluri 28 82 2011 10.1007/s11095-010-0122-x Formation and closure of microchannels in skin following microporation
J. Control. Release Gupta 2011 10.1016/j.jconrel.2011.05.021 Kinetics of skin resealing after insertion of microneedles in human subjects
Pharm. Res. Banks 28 5 1211 2011 10.1007/s11095-011-0372-2 Diclofenac enables prolonged delivery of naltrexone through microneedle-treated skin
J. Control. Release Chen 139 63 2009 10.1016/j.jconrel.2009.05.031 Iontophoresis-driven penetration of nanovesicles through microneedle-induced skin microchannels for enhancing transdermal delivery of insulin
J. Control. Release Wu 118 189 2007 10.1016/j.jconrel.2006.12.017 Enhancement of skin permeation of high molecular compounds by a combination of microneedle pretreatment and iontophoresis
Pharm. Res. Badkar 24 7 1389 2007 10.1007/s11095-007-9308-2 Transdermal delivery of interferon alpha-2B using microporation and iontophoresis in hairless rats
Int. J. Pharm. Katikaneni 378 93 2009 10.1016/j.ijpharm.2009.05.050 Molecular charge mediated transport of a 13kD protein across microporated skin
Pharm. Res. Lin 18 12 2001 10.1023/A:1013395102049 Transdermal delivery of antisense oligonucleotides with microprojection patch (Macroflux) technology
Nat. Med. Mikszta 8 415 2002 10.1038/nm0402-415 Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery
Hum. Vaccin. Dean 1 3 106 2005 10.4161/hv.1.3.1797 Cutaneous delivery of a live, attenuated chimeric flavivirus vaccine against Japanese encephalitis (ChimeriVax)-JE in non-human primates
Eur. J. Pharm. Sci. Gill 38 95 2009 10.1016/j.ejps.2009.06.004 Selective removal of stratum corneum by microdermabrasion to increase skin permeability
Vaccine Pearton 28 6104 2010 10.1016/j.vaccine.2010.05.055 Influenza virus-like particles coated onto microneedles can elicit stimulatory effects on Langerhans cells in human skin
J. Infect. Dis. Mikszta 191 2 278 2005 10.1086/426865 Protective immunization against inhalational anthrax: a comparison of minimally invasive delivery platforms
Vaccine Laurent 28 5850 2010 10.1016/j.vaccine.2010.06.062 Safety and efficacy of novel dermal and epidermal microneedle delivery systems for rabies vaccination in healthy adults
Microsyst. Technol. Chen 14 7 1015 2007 10.1007/s00542-007-0530-y Silicon microneedle array with biodegradable tips for transdermal drug delivery
Biomaterials Lee 2011 10.1016/j.biomaterials.2011.06.058 A high-capacity, hybrid electro-microneedle for in-situ cutaneous gene transfer
D. Scholten, M. Stumber, F. Laermer, A. Feyh, Manufacturing method for a porous microneedle array and corresponding porous microneedle array and corresponding substrate composite, United States Patent Application 20110137254 (2011).
M.G. Allen, M.R. Prausnitz, D.V. McAllister, F.P.M. Cros, Microneedle Devices and Methods of Manufacture and Use Thereof, US 2010/0312191 A1 (2010).
J. Micromech. Microeng. Ji 16 5 958 2006 10.1088/0960-1317/16/5/012 Microfabricated microneedle with porous tip for drug delivery
Biomed. Microdevices Park 9 223 2007 10.1007/s10544-006-9024-4 Polymer particle-based micromolding to fabricate novel microstructures
J. Mater. Sci. Mater. Med. Shirkhanzadeh 16 1 37 2005 10.1007/s10856-005-6444-2 Microneedles coated with porous calcium phosphate ceramics: effective vehicles for transdermal delivery of solid trehalosea
Pharm. Res. Gill 24 7 1369 2007 10.1007/s11095-007-9286-4 Coating formulations for microneedles
J. Control. Release Gill 117 227 2007 10.1016/j.jconrel.2006.10.017 Coated microneedles for transdermal delivery
J. Phys. Chem. Solids Gill 69 5-6 1537 2008 10.1016/j.jpcs.2007.10.059 Pocketed microneedles for drug delivery to the skin
J. Biomed. Mater. Res. Matsuda 62 3 395 2002 10.1002/jbm.10295 Liquid acrylate-endcapped biodegradable poly(?-caprolactone-co-trimethylene carbonate). II. Computer-aided stereolithographic microarchitectural surface photoconstructs
Pharm. Res. Donnelly 28 1 41 2011 10.1007/s11095-010-0169-8 Design, optimization and characterisation of polymeric microneedle arrays prepared by a novel laser-based micromoulding technique
Int. J. Pharm. McGrath 415 140 2011 10.1016/j.ijpharm.2011.05.064 Determination of parameters for successful spray coating of silicon microneedle arrays
J. Control. Release Chen 139 212 2009 10.1016/j.jconrel.2009.06.029 Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin
Pharm. Res. Zhang 2011 Development of lidocaine-coated microneedle product for rapid, safe, and prolonged local analgesic action
Nanomedicine Xie 1 184 2005 10.1016/j.nano.2005.03.001 Controlled transdermal delivery of model drug compounds by MEMS microneedle array
Gene Ther. Gill 17 811 2010 10.1038/gt.2010.22 Cutaneous vaccination using microneedles coated with hepatitis C DNA vaccine
Biomacromolecules Saurer 11 3136 2010 10.1021/bm1009443 Layer-by-layer assembly of DNA- and protein-containing films on microneedles for drug delivery to the skin
PLoS One Koutsonanos 4 3 e4773 2009 10.1371/journal.pone.0004773 Transdermal influenza immunization with vaccine-coated microneedle arrays
PLoS One Quan 4 9 e7215 2009 10.1371/journal.pone.0007152 Stabilization of influenza vaccine enhances protection by microneedle delivery in the mouse skin
Proc. Natl. Acad. Sci. U. S. A. Zhu 106 19 7968 2009 10.1073/pnas.0812652106 Immunization by vaccine-coated microneedle arrays protects against lethal influenza virus challenge
J. Virol. Quan 84 15 7760 2010 10.1128/JVI.01849-09 Intradermal vaccination with influenza virus-like particles by using microneedles induces protection superior to that with intramuscular immunization
J. Control. Release Kim 142 3 187 2010 10.1016/j.jconrel.2009.10.013 Formulation and coating of microneedles with inactivated influenza virus to improve vaccine stability and immunogenicity
AAPS PharmSciTech Kim 11 3 1193 2010 10.1208/s12249-010-9471-3 Formulation of microneedles coated with influenza virus-like particle vaccine
J. Infect. Dis. Kim 201 2 190 2010 10.1086/649228 Enhanced memory responses to seasonal H1N1 influenza vaccination of the skin with the use of vaccine-coated microneedles
Pharm. Res. Kim 28 1 135 2010 10.1007/s11095-010-0134-6 Stability kinetics of influenza vaccine coated onto microneedles during drying and storage
Vaccine Kim 27 6932 2009 10.1016/j.vaccine.2009.08.108 Improved influenza vaccination in the skin using vaccine coated microneedles
Martin 2009 Aerosol coating of microneedles, WO/2009/081125
Pharm. Res. Ameri 26 11 2454 2009 10.1007/s11095-009-9960-9 Demonstrated solid-state stability of parathyroid hormone PTH(1-34) coated on a novel transdermal microprojection delivery system
Pharm. Res. Andrianov 28 58 2011 10.1007/s11095-010-0133-7 Microneedles with intrinsic immunoadjuvant properties: microfabrication, protein stability, and modulated release
Proc. Natl. Acad. Sci. U. S. A. Andrianov 106 45 18936 2009 10.1073/pnas.0908842106 Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization
J. Appl. Polym. Sci. Marin 121 395 2011 10.1002/app.33608 Carboxymethylcellulose-chitosan-coated microneedles with modulated hydration properties
ACS Nano Su 3 11 3719 2009 10.1021/nn900928u Layer-by-layer-assembled multilayer films for transcutaneous drug and vaccine delivery
Adv. Mater. DeMuth 22 4851 2010 10.1002/adma.201001525 Nano-layered microneedles for transcutaneous delivery of polymer nanoparticles and plasmid DNA
J. Control. Release Verheul 2011 10.1016/j.jconrel.2011.07.014 Covalently stabilized trimethyl chitosan-hyaluronic acid nanoparticles for nasal and intradermal vaccination
Vaccine Bal 29 23 4025 2011 10.1016/j.vaccine.2011.03.039 Small is beautiful: N-trimethyl chitosan-ovalbumin conjugates for microneedle-based transcutaneous immunisation
J. Control. Release Bal 142 3 374 2010 10.1016/j.jconrel.2009.11.018 Efficient induction of immune responses through intradermal vaccination with N-trimethyl chitosan containing antigen formulations
J. Control. Release Slutter 2011 10.1016/j.jconrel.2011.02.007 Adjuvant effect of cationic liposomes and CpG depends on administration route
Small Raphael 6 16 1785 2010 10.1002/smll.201000326 Targeted, needle-free vaccinations in skin using multilayered, densely-packed dissolving microprojection arrays
Int. J. Nanomed. Kumar 6 1253 2011 Permeation of antigen protein-conjugated nanoparticles and live bacteria through microneedle-treated mouse skin
Pharm. Res. Nordquist 24 7 1381 2007 10.1007/s11095-007-9256-x Novel microneedle patches for active insulin delivery are efficient in maintaining glycaemic control: an initial comparison with subcutaneous administration
Diabetes Technol. Ther. Gupta 11 6 329 2009 10.1089/dia.2008.0103 Minimally invasive insulin delivery in subjects with type 1 diabetes using hollow microneedles
Pharm. Res. Martanto 21 6 947 2004 10.1023/B:PHAM.0000029282.44140.2e Transdermal delivery of insulin using microneedles in vivo
Biomed. Microdevices Wu 12 4 665 2010 10.1007/s10544-010-9419-0 Sustained release of insulin through skin by intradermal microdelivery system
Diabetes Technol. Ther. Gupta 13 4 451 2011 10.1089/dia.2010.0204 Rapid pharmacokinetics of intradermal insulin administered using microneedles in type 1 diabetes subjects
Diabetes Technol. Ther. Pettis 13 4 435 2011 10.1089/dia.2010.0184 Intradermal microneedle delivery of insulin lispro achieves faster insulin absorption and insulin action than subcutaneous injection
Diabetes Technol. Ther. Pettis 13 4 443 2011 10.1089/dia.2010.0183 Microneedle-based intradermal versus subcutaneous administration of regular human insulin or insulin lispro: pharmacokinetics and postprandial glycemic excursions in patients with type 1 diabetes
Pharm. Res. Hermeling 22 1997 2005 10.1007/s11095-005-8177-9 Structural characterization and immunogenicity in immune tolerant mice of recombinant human interferon alpha2b
J. Pharm. Sci. Hermeling 95 1084 2006 10.1002/jps.20599 Antibody response to aggregated human interferon alpha2b in wildtype and transgenic immune tolerant mice depends on type and level of aggregation
Pharm. Res. Beers 28 2393 2011 10.1007/s11095-011-0451-4 Oxidized and aggregated recombinant interferon beta is immunogenic in human interferon beta transgenic mice
Zosano-Pharma
NanoPass-Technologies
Clin. J. Pain Gupta 2011 Rapid local anesthesia in humans using minimally invasive microneedles
Am. J. Emerg. Med. Li 28 130 2010 10.1016/j.ajem.2008.10.001 Microneedle pretreatment improves efficacy of cutaneous topical anesthesia
Proc. Natl. Acad. Sci. U. S. A. Wermeling 105 6 2058 2008 10.1073/pnas.0710355105 Microneedles permit transdermal delivery of a skin-impermeant medication to humans
Vaccine Leroux-Roels 26 51 6614 2008 10.1016/j.vaccine.2008.09.078 Seasonal influenza vaccine delivered by intradermal microinjection: a randomised controlled safety and immunogenicity trial in adults
BMC Med. Beran 7 13 2009 Intradermal influenza vaccination of healthy adults using a new microinjection system: a 3-year randomised controlled safety and immunogenicity trial
Vaccine Damme 27 3 454 2009 10.1016/j.vaccine.2008.10.077 Safety and efficacy of a novel microneedle device for dose sparing intradermal influenza vaccination in healthy adults
Pharm. Res. Hermeling 21 6 897 2004 10.1023/B:PHAM.0000029275.41323.a6 Structure-immunogenicity relationships of therapeutic proteins
Nephrol. Dial. Transplant. Schellekens Suppl. 6 vi3 2005 10.1093/ndt/gfh1092 Factors influencing the immunogenicity of therapeutic proteins
Biotechnol. Annu. Rev. Schellekens 14 191 2008 10.1016/S1387-2656(08)00007-0 How to predict and prevent the immunogenicity of therapeutic proteins
Trends Pharmacol. Sci. Sauerborn 31 2 53 2010 10.1016/j.tips.2009.11.001 Immunological mechanism underlying the immune response to recombinant human protein therapeutics
J. Pharm. Sci. Singh 100 2 354 2011 10.1002/jps.22276 Impact of product-related factors on immunogenicity of biotherapeutics
BioProcess Int. Arakawa 4 10 42 2006 Aggregation analysis of therapeutic proteins, Part 1
AAPS J. Rosenberg 8 3 E501 2006 10.1208/aapsj080359 Effects of protein aggregates: an immunologic perspective
J. Pharm. Sci. Singh 99 8 3302 2010 10.1002/jps.22097 An industry perspective on the monitoring of subvisible particles as a quality attribute for protein therapeutics
Pharm. Res. Engelsman 28 4 920 2011 10.1007/s11095-010-0297-1 Strategies for the assessment of protein aggregates in pharmaceutical biotech product development
Pharm. Res. Brinks 28 2379 2011 10.1007/s11095-011-0523-5 Immunogenicity of therapeutic proteins: the use of animal models
Zahn 2000 Microfabricated Microdialysis Microneedles for Continuous Medical Monitoring
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