$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

The effects of pycnogenol on antioxidant enzymes in a mouse model of ozone exposure

The Korean journal of internal medicine : KJIM, v.28 no.2, 2013년, pp.216 - 223  

Lee, Min-Sung (Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.) ,  Moon, Kuk-Young (Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.) ,  Bae, Da-Jeong (Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.) ,  Park, Moo-Kyun (Department of Otolaryngology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.) ,  Jang, An-Soo (Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.)

Abstract AI-Helper 아이콘AI-Helper

Background/AimsOzone is an environmentally reactive oxidant, and pycnogenol is a mixture of flavonoid compounds extracted from pine tree bark that have antioxidant activity. We investigated the effects of pycnogenol on reactive nitrogen species, antioxidant responses, and airway responsiveness in BA...

주제어

참고문헌 (55)

  1. 1 Jang AS Yeum CH Son MH Epidemiologic evidence of a relationship between airway hyperresponsiveness and exposure to polluted air Allergy 2003 58 585 588 12823115 

  2. 2 Jang AS Choi IS Yang SY Antioxidant responsiveness in BALB/c mice exposed to ozone Respiration 2005 72 79 84 15753639 

  3. 3 Jang AS Choi IS Lee JU Park SW Lee JH Park CS Changes in the expression of NO synthase isoforms after ozone: the effects of allergen exposure Respir Res 2004 5 5 15251042 

  4. 4 Jang AS Choi IS Kim SW Song BC Yeum CH Jung JY Airway obstruction after acute ozone exposure in BALB/c mice using barometric plethysmography Korean J Intern Med 2003 18 1 5 12760261 

  5. 5 Jang AS Choi IS Lee JU Neuronal nitric oxide synthase is associated with airway obstruction in BALB/c mice exposed to ozone Respiration 2003 70 95 99 12584398 

  6. 6 Jang AS Choi IS Koh YI Park CS Lee JS The relationship between alveolar epithelial proliferation and airway obstruction after ozone exposure Allergy 2002 57 737 740 12121195 

  7. 7 Jang AS Choi IS Lee JH Park CS Prolonged ozone exposure in an allergic airway disease model: adaptation of airway responsiveness and airway remodeling Respir Res 2006 7 24 16472404 

  8. 8 Leikauf GD Zhao Q Zhou S Santrock J Ozonolysis products of membrane fatty acids activate eicosanoid metabolism in human airway epithelial cells Am J Respir Cell Mol Biol 1993 9 594 602 8257591 

  9. 9 Mikerov AN Umstead TM Gan X Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants Am J Physiol Lung Cell Mol Physiol 2008 294 L121 L130 17981957 

  10. 10 Kafoury RM Pryor WA Squadrito GL Salgo MG Zou X Friedman M Induction of inflammatory mediators in human airway epithelial cells by lipid ozonation products Am J Respir Crit Care Med 1999 160 1934 1942 10588609 

  11. 11 Kafoury RM Pryor WA Squadrito GL Salgo MG Zou X Friedman M Lipid ozonation products activate phospholipases A2, C, and D Toxicol Appl Pharmacol 1998 150 338 349 9653065 

  12. 12 Packer L Rimbach G Virgili F Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol Free Radic Biol Med 1999 27 704 724 10490291 

  13. 13 Rice-Evans CA Miller NJ Antioxidant activities of flavonoids as bioactive components of food Biochem Soc Trans 1996 24 790 795 8878849 

  14. 14 Boege F Straub T Kehr A Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I J Biol Chem 1996 271 2262 2270 8567688 

  15. 15 Koley AP Buters JT Robinson RC Markowitz A Friedman FK Differential mechanisms of cytochrome P450 inhibition and activation by alpha-naphthoflavone J Biol Chem 1997 272 3149 3152 9013547 

  16. 16 De Azevedo WF Jr Mueller-Dieckmann HJ Schulze-Gahmen U Worland PJ Sausville E Kim SH Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase Proc Natl Acad Sci U S A 1996 93 2735 2740 8610110 

  17. 17 Moini H Guo Q Packer L Enzyme inhibition and protein-binding action of the procyanidin-rich french maritime pine bark extract, pycnogenol: effect on xanthine oxidase J Agric Food Chem 2000 48 5630 5639 11087530 

  18. 18 Saliou C Rimbach G Moini H Solar ultraviolet-induced erythema in human skin and nuclear factor-kappa-B-dependent gene expression in keratinocytes are modulated by a French maritime pine bark extract Free Radic Biol Med 2001 30 154 160 11163532 

  19. 19 Ueda T Armstrong D Preventive effect of natural and synthetic antioxidants on lipid peroxidation in the mammalian eye Ophthalmic Res 1996 28 184 192 8829176 

  20. 20 van Jaarsveld H Kuyl JM Schulenburg DH Wiid NM Effect of flavonoids on the outcome of myocardial mitochondrial ischemia/reperfusion injury Res Commun Mol Pathol Pharmacol 1996 91 65 75 8824932 

  21. 21 Rong Y Li L Shah V Lau BH Pycnogenol protects vascular endothelial cells from t-butyl hydroperoxide induced oxidant injury Biotechnol Ther 1994 5 117 126 8608322 

  22. 22 Cheshier JE Ardestani-Kaboudanian S Liang B Immunomodulation by pycnogenol in retrovirus-infected or ethanol-fed mice Life Sci 1996 58 PL87 PL96 

  23. 23 Committee of the Environmental and Occupational Health Assembly of the American Thoracic Society Health effects of outdoor air pollution Am J Respir Crit Care Med 1996 153 3 50 8542133 

  24. 24 Holtzman MJ Fabbri LM O'Byrne PM Importance of airway inflammation for hyperresponsiveness induced by ozone Am Rev Respir Dis 1983 127 686 690 6859651 

  25. 25 Gordon T Taylor BF Amdur MO Ozone inhibition of tissue cholinesterase in guinea pigs Arch Environ Health 1981 36 284 288 7316565 

  26. 26 Kelly FJ Blomberg A Frew A Holgate ST Sandstrom T Antioxidant kinetics in lung lavage fluid following exposure of humans to nitrogen dioxide Am J Respir Crit Care Med 1996 154 6 Pt 1 1700 1705 8970358 

  27. 27 Wiester MJ Winsett DW Richards JH Jackson MC Crissman KM Costa DL Ozone adaptation in mice and its association with ascorbic acid in the lung Inhal Toxicol 2000 12 577 590 10880145 

  28. 28 Freed AN Cueto R Pryor WA Antioxidant transport modulates peripheral airway reactivity and inflammation during ozone exposure J Appl Physiol 1999 87 1595 1603 10562596 

  29. 29 Jacky JP A plethysmograph for long-term measurements of ventilation in unrestrained animals J Appl Physiol 1978 45 644 647 101497 

  30. 30 Mudway IS Housley D Eccles R Differential depletion of human respiratory tract antioxidants in response to ozone challenge Free Radic Res 1996 25 499 513 8951423 

  31. 31 Bieri JG Poukka RK Prival EL Determination of alpha-tocopherol in erythrocytes by gas-liquid chromatography J Lipid Res 1970 11 118 123 5418474 

  32. 32 Blomberg A Mudway IS Nordenhall C Ozone-induced lung function decrements do not correlate with early airway inflammatory or antioxidant responses Eur Respir J 1999 13 1418 1428 10445622 

  33. 33 Ohkawa H Ohishi N Yagi K Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal Biochem 1979 95 351 358 36810 

  34. 34 Greenberg SS Xie J Spitzer JJ Nitro containing L-arginine analogs interfere with assays for nitrate and nitrite Life Sci 1995 57 1949 1961 7475944 

  35. 35 Bast A Weseler AR Haenen GR den Hartog GJ Oxidative stress and antioxidants in interstitial lung disease Curr Opin Pulm Med 2010 16 516 520 20592594 

  36. 36 Finkel T Signal transduction by reactive oxygen species J Cell Biol 2011 194 7 15 21746850 

  37. 37 Balaban RS Nemoto S Finkel T Mitochondria, oxidants, and aging Cell 2005 120 483 495 15734681 

  38. 38 Comhair SA Erzurum SC Redox control of asthma: molecular mechanisms and therapeutic opportunities Antioxid Redox Signal 2010 12 93 124 19634987 

  39. 39 Kliment CR Oury TD Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis Free Radic Biol Med 2010 49 707 717 20452419 

  40. 40 Wood LG Wark PA Garg ML Antioxidant and anti-inflammatory effects of resveratrol in airway disease Antioxid Redox Signal 2010 13 1535 1548 20214495 

  41. 41 Park HS Kim SR Lee YC Impact of oxidative stress on lung diseases Respirology 2009 14 27 38 19144046 

  42. 42 Cho YS Moon HB The role of oxidative stress in the pathogenesis of asthma Allergy Asthma Immunol Res 2010 2 183 187 20592917 

  43. 43 Nadeem A Masood A Siddiqui N Oxidant: antioxidant imbalance in asthma: scientific evidence, epidemiological data and possible therapeutic options Ther Adv Respir Dis 2008 2 215 235 19124374 

  44. 44 Macnee W Rahman I Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease Am J Respir Crit Care Med 1999 160 5 Pt 2 S58 S65 10556172 

  45. 45 Rohdewald P Rice-Evans C Packer L Pycnogenol Flavonoids in Health and Disease 1998 New York Marcel Dekker 405 419 

  46. 46 Masquelier J Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenging effect and use thereof United States patent US 4,698,360 1987 10 06 

  47. 47 Blazso G Gabor M Sibbel R Rohewald P Antiinflammatory and superoxide radical scavenging activities of procyanidins containing extract from the bark of Pinus pinaster Sol. and its fractions Pharmaceut Pharmacol Lett 1994 3 217 220 

  48. 48 Virgili F Kobuchi H Packer L Procyanidins extracted from Pinus maritima (Pycnogenol): scavengers of free radical species and modulators of nitrogen monoxide metabolism in activated murine RAW 264.7 macrophages Free Radic Biol Med 1998 24 1120 1129 9626566 

  49. 49 Heffner JE Repine JE Pulmonary strategies of antioxidant defense Am Rev Respir Dis 1989 140 531 554 2669581 

  50. 50 Burton GW Joyce A Ingold KU First proof that vitamin E is major lipid-soluble, chain-breaking antioxidant in human blood plasma Lancet 1982 2 327 6124736 

  51. 51 McCay PB Vitamin E: interactions with free radicals and ascorbate Annu Rev Nutr 1985 5 323 340 2992548 

  52. 52 Romieu I Meneses F Ramirez M Antioxidant supplementation and respiratory functions among workers exposed to high levels of ozone Am J Respir Crit Care Med 1998 158 226 232 9655734 

  53. 53 Kari F Hatch G Slade R Crissman K Simeonova PP Luster M Dietary restriction mitigates ozone-induced lung inflammation in rats: a role for endogenous antioxidants Am J Respir Cell Mol Biol 1997 17 740 747 9409561 

  54. 54 Morabia A Menkes MJ Comstock GW Tockman MS Serum retinol and airway obstruction Am J Epidemiol 1990 132 77 82 2356816 

  55. 55 Shahar E Folsom AR Melnick SL The Atherosclerosis Risk in Communities (ARIC) Study Investigators Does dietary vitamin A protect against airway obstruction? Am J Respir Crit Care Med 1994 150 978 982 7921473 

LOADING...

관련 콘텐츠

오픈액세스(OA) 유형

GOLD

오픈액세스 학술지에 출판된 논문

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트