최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Cell, v.161 no.7, 2015년, pp.1681 - 1696
The Cancer Genome Atlas Network
We describe the landscape of genomic alterations in cutaneous melanomas through DNA, RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 patients. We establish a framework for genomic classification into one of four subtypes based on the pattern of the most prevalent ...
Nat. Genet. Andersen 3 118 1993 10.1038/ng0293-118 Mutations in the neurofibromatosis 1 gene in sporadic malignant melanoma cell lines
J. Transl. Med. Ascierto 12 116 2014 10.1186/1479-5876-12-116 Clinical experience with ipilimumab 3 mg/kg: real-world efficacy and safety data from an expanded access programme cohort
J. Clin. Oncol. Azimi 30 2678 2012 10.1200/JCO.2011.37.8539 Tumor-infiltrating lymphocyte grade is an independent predictor of sentinel lymph node status and survival in patients with cutaneous melanoma
Int. J. Cancer Baade 130 170 2012 10.1002/ijc.25996 Time trends and latitudinal differences in melanoma thickness distribution in Australia, 1990-2006
J. Clin. Oncol. Balch 27 6199 2009 10.1200/JCO.2009.23.4799 Final version of 2009 AJCC melanoma staging and classification
J. Clin. Oncol. Balch 28 2452 2010 10.1200/JCO.2009.27.1627 Multivariate analysis of prognostic factors among 2,313 patients with stage III melanoma: comparison of nodal micrometastases versus macrometastases
Nature Berger 485 502 2012 10.1038/nature11071 Melanoma genome sequencing reveals frequent PREX2 mutations
Proc. Natl. Acad. Sci. USA Bogunovic 106 20429 2009 10.1073/pnas.0905139106 Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival
N. Engl. J. Med. Brahmer 366 2455 2012 10.1056/NEJMoa1200694 Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
Photochem. Photobiol. Brash 91 15 2015 10.1111/php.12377 UV signature mutations
Cell Brennan 155 462 2013 10.1016/j.cell.2013.09.034 The somatic genomic landscape of glioblastoma
Nat. Biotechnol. Carter 30 413 2012 10.1038/nbt.2203 Absolute quantification of somatic DNA alterations in human cancer
JAMA Carvajal 305 2327 2011 10.1001/jama.2011.746 KIT as a therapeutic target in metastatic melanoma
J. Invest. Dermatol. Criscione 130 793 2010 10.1038/jid.2009.328 Melanoma thickness trends in the United States, 1988-2006
N. Engl. J. Med. Curtin 353 2135 2005 10.1056/NEJMoa050092 Distinct sets of genetic alterations in melanoma
Surg. Gynecol. Obstet. Dasgupta 117 341 1963 Malignant Melanoma of Unknown Primary Origin
Br. J. Cancer Draper 53 661 1986 10.1038/bjc.1986.110 Second primary neoplasms in patients with retinoblastoma
Oncotarget Dutton-Regester 5 2912 2014 10.18632/oncotarget.2048 A highly recurrent RPS27 5′UTR mutation in melanoma
Lancet Eggermont 372 117 2008 10.1016/S0140-6736(08)61033-8 Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial
Cancer Res. Erdag 72 1070 2012 10.1158/0008-5472.CAN-11-3218 Immunotype and immunohistologic characteristics of tumor-infiltrating immune cells are associated with clinical outcome in metastatic melanoma
Curr. Opin. Ophthalmol. Field 25 234 2014 10.1097/ICU.0000000000000051 Recent developments in prognostic and predictive testing in uveal melanoma
PLoS ONE Frederick 9 e101286 2014 10.1371/journal.pone.0101286 Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics
N. Engl. J. Med. Gershenwald 364 1738 2011 10.1056/NEJMct1002967 Sentinel-lymph-node biopsy for cutaneous melanoma
Mol. Cancer Res. Gold 12 433 2014 10.1158/1541-7786.MCR-13-0422 PP6C hotspot mutations in melanoma display sensitivity to Aurora kinase inhibition
N. Engl. J. Med. Hamid 369 134 2013 10.1056/NEJMoa1305133 Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
Nat. Med. Helming 20 251 2014 10.1038/nm.3480 ARID1B is a specific vulnerability in ARID1A-mutant cancers
J. Clin. Oncol. Hodi 26 2046 2008 10.1200/JCO.2007.14.0707 Major response to imatinib mesylate in KIT-mutated melanoma
Cell Hodis 150 251 2012 10.1016/j.cell.2012.06.024 A landscape of driver mutations in melanoma
Science Horn 339 959 2013 10.1126/science.1230062 TERT promoter mutations in familial and sporadic melanoma
Science Huang 339 957 2013 10.1126/science.1229259 Highly recurrent TERT promoter mutations in human melanoma
J. Invest. Dermatol. Jayaraman 134 213 2014 10.1038/jid.2013.276 Mutational landscape of basal cell carcinomas by whole-exome sequencing
Clin. Cancer Res. Ji 19 4383 2013 10.1158/1078-0432.CCR-13-0074 Vemurafenib synergizes with nutlin-3 to deplete survivin and suppresses melanoma viability and tumor growth
J. Clin. Oncol. Kirkwood 14 7 1996 10.1200/JCO.1996.14.1.7 Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684
Nat. Genet. Krauthammer 44 1006 2012 10.1038/ng.2359 Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
Acta Neuropathol. Kusters-Vandevelde 119 317 2010 10.1007/s00401-009-0611-3 Activating mutations of the GNAQ gene: a frequent event in primary melanocytic neoplasms of the central nervous system
Nature Lawrence 499 214 2013 10.1038/nature12213 Mutational heterogeneity in cancer and the search for new cancer-associated genes
Nature Lawrence 505 495 2014 10.1038/nature12912 Discovery and saturation analysis of cancer genes across 21 tumour types
Biochem. Biophys. Res. Commun. Lopez 398 585 2010 10.1016/j.bbrc.2010.06.125 IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain
Pigment Cell Melanoma Res. Lutzky 21 492 2008 10.1111/j.1755-148X.2008.00475.x Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation
Cancer Discov. Maertens 3 338 2013 10.1158/2159-8290.CD-12-0313 Elucidating distinct roles for NF1 in melanomagenesis
J. Invest. Dermatol. Mann 133 509 2013 10.1038/jid.2012.283 BRAF mutation, NRAS mutation, and the absence of an immune-related expressed gene profile predict poor outcome in patients with stage III melanoma
J. Clin. Oncol. McArthur 31 499 2013 10.1200/JCO.2012.45.5568 Targeting oncogenic drivers and the immune system in melanoma
Lab. Invest. Mihm 74 43 1996 Tumor infiltrating lymphocytes in lymph node melanoma metastases: a histopathologic prognostic indicator and an expression of local immune response
N. Engl. J. Med. Morton 370 599 2014 10.1056/NEJMoa1310460 Final trial report of sentinel-node biopsy versus nodal observation in melanoma
Nat. Genet. Nikolaev 44 133 2012 10.1038/ng.1026 Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma
Cancer Res. Nissan 74 2340 2014 10.1158/0008-5472.CAN-13-2625 Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence
Cancer Cell Noushmehr 17 510 2010 10.1016/j.ccr.2010.03.017 Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
Nat. Genet. Pollock 33 19 2003 10.1038/ng1054 High frequency of BRAF mutations in nevi
PLoS ONE Rakosy 8 e54958 2013 10.1371/journal.pone.0054958 Integrative genomics identifies gene signature associated with melanoma ulceration
Pigment Cell Melanoma Res. Ranzani 28 117 2015 10.1111/pcmr.12316 BRAF/NRAS wild-type melanoma, NF1 status and sensitivity to trametinib
Nat. Med. Robbins 19 747 2013 10.1038/nm.3161 Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
Lancet Robert 384 1109 2014 10.1016/S0140-6736(14)60958-2 Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
J. Cutan. Pathol. Santa Cruz 24 533 1997 10.1111/j.1600-0560.1997.tb01457.x Differential expression of metallopanstimulin/S27 ribosomal protein in melanocytic lesions of the skin
Cancer Res. Shields 67 1502 2007 10.1158/0008-5472.CAN-06-3311 Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma
N. Engl. J. Med. Snyder 371 2189 2014 10.1056/NEJMoa1406498 Genetic basis for clinical response to CTLA-4 blockade in melanoma
J. Med. Chem. Sun 57 1454 2014 10.1021/jm401753e Discovery of AMG 232, a potent, selective, and orally bioavailable MDM2-p53 inhibitor in clinical development
Nature 455 1061 2008 10.1038/nature07385 Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Nature 489 519 2012 10.1038/nature11404 Comprehensive genomic characterization of squamous cell lung cancers
Nature 507 315 2014 10.1038/nature12965 Comprehensive molecular characterization of urothelial bladder carcinoma
Nature 511 543 2014 10.1038/nature13385 Comprehensive molecular profiling of lung adenocarcinoma
J. Invest. Dermatol. Terheyden 130 314 2010 10.1038/jid.2009.197 Response to imatinib mesylate depends on the presence of the V559A-mutated KIT oncogene
N. Engl. J. Med. Topalian 366 2443 2012 10.1056/NEJMoa1200690 Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
Genes Dev. Tsao 26 1131 2012 10.1101/gad.191999.112 Melanoma: from mutations to medicine
Nature Tumeh 515 568 2014 10.1038/nature13954 PD-1 blockade induces responses by inhibiting adaptive immune resistance
Cancer Discov. Van Allen 4 94 2014 10.1158/2159-8290.CD-13-0617 The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma
Cancer Res. Watson 74 4845 2014 10.1158/0008-5472.CAN-14-1232-T The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF
Cancer Discov. Whittaker 3 350 2013 10.1158/2159-8290.CD-12-0470 A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition
J. Natl. Cancer Inst. Winnepenninckx 98 472 2006 10.1093/jnci/djj103 Gene expression profiling of primary cutaneous melanoma and clinical outcome
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문
※ AI-Helper는 부적절한 답변을 할 수 있습니다.