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Simultaneous determination and pharmacokinetics of four triterpenoids by ultra high performance liquid chromatography with tandem mass spectrometry after the oral administration of Acanthopanax sessiliflorus (Rupr. et Maxim) Seem extract

Journal of separation science, v.39 no.12, 2016년, pp.2229 - 2237  

Song, Yang (School of Pharmacy, China Medical University, Shenyang, China) ,  Wang, Zhibin (Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin, China) ,  Feng, Xuesong (School of Pharmacy, China Medical University, Shenyang, China) ,  Deng, Xiaolan (School of Pharmacy, China Medical University, Shenyang, China) ,  Zhu, Juan (School of Pharmacy, China Medical University, Shenyang, China)

Abstract AI-Helper 아이콘AI-Helper

A specific, simple, and sensitive ultra high performance liquid chromatography with tandem mass spectrometry method utilizing the Triple Quad system has been developed and validated for the simultaneous determination and pharmacokinetic study of four triterpenoid components of Acanthopanax sessilifl...

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참고문헌 (26)

  1. Zhou , Z.C. , Wang , G.Z. , Song , X.K. , Anti‐allergic inflammation the ethanol extract of Acanthopanax sessiliflorus . J. Tradit. Chin. Med . 1985 , 10 , 37 – 41 . 

  2. Lee , S.H. , Lee , Y.S. , Jung , S.H. , Ji , J. , Shin , K.H. , Kin , B.K. , Kang , S.S. , Antitumor and immunostimulating activities of Acanthopanax sessiliflorus fruit . Nat. Prod. Sci . 2003 , 9 , 112 – 116 . 

  3. Jeong , S.C. , Jeong , Y.T. , Yang , B.K. , Song , C.H. , Chemical characteristics and immuno‐stimulating properties of biopolymers extracted from Acanthopanax sessiliflorus . J. Biochem. Mol. Biol . 2006 , 39 , 84 – 90 . 

  4. Billingham , M.E.J. , Experimental models of arthritis in animals as screening tests for drugs to treat arthritis in man . Handb. Exp. Pharmacol . 1979 , 50 , 108 – 114 . 

  5. Feng , Y. , Meng , X.J. , Wang , J.G. , Wang , J.J. , Zhang , Q. , Study on constituents and biological activities of polyose from Acanthopanax sessiliflorus (Rupr. et Maxim) Seem fruit . Food Sci . 2008 , 9 , 378 – 380 . 

  6. Jin , J.L. , Lee , S. , Lee , Y.Y. , Kim , J.M. , Heo , J.E. , Yun‐Choi , H.S. , Platelet antiaggregating triterpenoids from the leaves of Acanthopanax senticosus and the fruits of A. sessiliflorus . Planta Med . 2004 , 70 , 564 – 566 . 

  7. An , Q. , Yang , C.J. , Song , Y. , Yu , K. , Xiong , Z.L. , Li , F.M. , Studies on the chemical constituents of the fruit of Acanthopanax sessiliflorus (Rupr.etMaxim.) Seem . Nat. Prod. Res. Dev . 2008 , 20 , 765 – 769 . 

  8. Yang , C.J. , An , Q. , Song , Y. , Xiong , Z.L. , Li , F.M. , Isolation and identification of chemical constituents of fruits of Acanthopanax sessiliflorus . China J. Chin. Mat. Med . 2009 , 34 , 715 – 717 . 

  9. Yang , C.J. , An , Q. , Xiong , Z.L. , Song , Y. , Yu , K. , Li , F.M. , Triterpenes from Acanthopanax sessiliflorus fruits and their antiplatelet aggregation activities . Planta Med . 2009 , 75 , 656 – 659 . 

  10. Yoshizumi , K. , Hirano , K. , Ando , H. , Hirai , Y. , Ida , Y. , Tsuji , T. , Tanaka , T. , Satouchi , K. , Terao , J. , Lupan‐type saponins from leaves of Acanthopanax sessiliflorus and their Inhibitory activity on pancreatic lipase . J. Anhui Agri. Sci . 2006 , 54 , 335 ‐ 341 . 

  11. Lee , S. , Kim , B.K. , Cho , S.H. , Shin , K.H. , Phytochemical constituents from the fruits of Acanthopanax sessiliflorus . Arch. Pharmacal. Res . 2002 , 25 , 280 – 284 . 

  12. Feng , Y. , Meng , X.J. , Wang , J.G. , Isolation, preparation and identification of hyperin from Acanthopanax sessiliflorus . Food Sci . 2007 , 28 , 298 – 300 . 

  13. Kong , L.Y. , Shao , C.J. , Xu , J.D. , Chemical constituents of the root of Acanthopanax sessiliflorus . Zhong Cao Yao 1988 , 19 , 482 – 486 . 

  14. Yook , C.S. , Lee , D.H. , Seo , Y.K. , Study on the constituents in the root bark of Acanthopanax sessiliflorum . Saengyak Hakhoechi 1977 , 8 , 31 – 34 . 

  15. Song , Y. , Yang , C.J. , Yu , K. , Li , F.M. , In vivo antithrombotic and antiplatelet activities of a quantified Acanthopanax sessiliflorus fruit extract . Chin. J. Nat. Med . 2011 , 9 , 141 – 145 . 

  16. Yang , C.J. , Yu , K. , Song , Y. , Qin , F. , Li , F.M. , Determination and pharmacokinetic study of chiisanogenin in rat plasma by ultra performance liquid chromatography‐tandem mass spectrometry . Phytochem. Anal . 2010 , 22 , 225 – 229 . 

  17. Yue , P.Y. , Wong , D.Y. , Wu , P.K. , Leung , P.Y. , Mak , N.K. , Yeung , H.W. , Liu , L. , Cai , Z. , Jiang , Z.H. , Fan , T.P. , Wong , R.N. , The angiosuppressive effects of 20(R)‐ginsenoside Rg3 . Biochem. Pharmacol . 2006 , 72 , 437 – 445 . 

  18. Chen , J.C. , Zhang , G.H. , Zhang , Z.Q. , Qiu , M.H. , Zheng , Y.T. , Yang , L.M. , Yu , K.B. , Octanorcucurbitane and cucurbitane triterpenoids from the tubers of hemsleya endecaphlla with HIV‐1 inhibitory activity . J. Nat. Prod . 2008 , 71 , 153 – 155 . 

  19. Jung , H.J. , Nam , J.H. , Choi , J. , Lee , K.T. , Park , H.J. , Antiinflammatory effects of chiisanoside and chiisanogenin obtained from the leaves of Acanthopanax chiisanensis in the carrageenan‐ and Freund's complete adjuvant‐induced rats . J. Ethnopharmacol . 2005 , 97 , 359 – 367 . 

  20. Lee , S. , Shin , D.S. , Oh , K.B. , Shin , K.H. , Antibacterial compounds from the leaves of Acanthopanax senticosus . Arch. Pharm. Res . 2003 , 26 , 40 – 42 . 

  21. Kim , Y.O. , Cho , D.H. , Chung , H.J. , Effects of lupane‐triterpenoids on mitogen‐induced proliferation of lymphocytes . Yakhak Hoechi 1999 , 43 , 208 – 213 . 

  22. Liu , L. , Yu , X.L. , Wang , Z.B. , Sun , J.H. , Pan , R. , Yang , C.J. , Wu , L.J. , Simultaneous determination and pharmacokinetics of five alkaloids in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry after the oral administration of Corydalis bungeana Turcz extract . J. Sep. Sci . 2015 , 00 , 1 – 10 . 

  23. Bae , S.H. , Lee , J.K. , Cho , D.Y. , Bae , S.K. , Simultaneous determination of metoprolol and its metabolites, α;‐hydroxymetoprolol and O‐desmethylmetoprolol, in human plasma by liquid chromatography with tandem mass spectrometry: application to the pharmacokinetics of metoprolol associated with CYP2D6 genotypes . J. Sep. Sci . 2014 , 11 : 1256 – 1264 . 

  24. Yang , C.J. , Wang , S.H. , Guo , X.W. , Sun , J.H. , Liu , L. , Wu , L.J. , Simultaneous determination of seven anthraquinones in rat plasma by Ultra High Performance Liquid Chromatography‐tandem Mass Spectrometry and pharmacokinetic study after oral administration of Semen Cassiae extract . J. Ethnopharmacol . 2015 , 169 , 305 – 313 . 

  25. Kitanaka , S. , Kimura , F. , Takido , M. , Studies on the constituents of the seeds of Cassia obtusifolia Linn. The structures of two new anthraquinoneglycosides . Chem. Pharm. Bull . 1985 , 33 , 1274 – 1276 . 

  26. Diehl , K.H. , Hull , R. , Morton , D. , Pfister , R. , Rabemampianina , Y. , Smith , D. , Vidal , J.M. , van de Vorstenbosch , C. , A good practice guide to the administration of substances and removal of blood, including routes and volumes . J. Appl. Toxicol . 2001 , 21 , 15 – 23 . 

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