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A heptameric peptide purified from Spirulina sp. gastrointestinal hydrolysate inhibits angiotensin I-converting enzyme- and angiotensin II-induced vascular dysfunction in human endothelial cells 원문보기

International journal of molecular medicine, v.39 no.5, 2017년, pp.1072 - 1082  

Heo, Seong-Yeong (Department of Biomedical Engineering, and Center for Marine-Integrated Biomedical Technology (BK21 Plus)) ,  Ko, Seok-Chun (Department of Biomedical Engineering, and Center for Marine-Integrated Biomedical Technology (BK21 Plus)) ,  Kim, Chang Su (Department of Orthopedic Surgery, Kosin University Gospel Hospital, Busan 49267, Republic of Korea) ,  Oh, Gun-Woo (Department of Biomedical Engineering, and Center for Marine-Integrated Biomedical Technology (BK21 Plus)) ,  Ryu, Bomi (School of Pharmacy, The University of Queensland, Brisbane, QLD 4072, Australia) ,  Qian, Zhong-Ji (College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, Guangdong 524088, P.R. China) ,  Kim, Geunhyung (Department of Bio-Mechatronic Engineering, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Gyeonggi 16419) ,  Park, Won Sun (Department of Physiology, Kangwon National University, School of Medicine, Chuncheon, Gangwon 24341) ,  Choi, Il-Whan (Department of Microbiology, Inje University College of Medicine, Busan 47392) ,  Phan, Thi Tuong Vy (Department of Biomedical Engineering, and Center for Marine-Integrat) ,  Heo, Soo-Jin ,  Kang, Do-Hyung ,  Yi, Myunggi ,  Jung, Won-Kyo

Abstract AI-Helper 아이콘AI-Helper

In this study, a marine microalga Spirulina sp.-derived protein was hydrolyzed using gastrointestinal enzymes to produce an angiotensin I (Ang I)-converting enzyme (ACE) inhibitory peptide. Following consecutive purification, the potent ACE inhibitory peptide was composed of 7 amino acids, Thr-Met-G...

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참고문헌 (44)

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