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Depressed serum IgM levels in SLE are restricted to defined subgroups 원문보기

Clinical immunology : the official journal of the Clinical Immunology Society, v.183, 2017년, pp.304 - 315  

Grönwall, Caroline (Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden) ,  Hardt, Uta (Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden) ,  Gustafsson, Johanna T. (Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden) ,  Elvin, Kerstin (Department of Clinical Immunology and Transfusion Medicine, Unit of Clinical Immunology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden) ,  Jensen-Urstad, Kerstin (Department of Clinical Physiology, Sö) ,  Kvarnström, Marika (dersjukhuset, Karolinska Institutet, Stockholm, Sweden) ,  Grosso, Giorgia (Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden) ,  Rönnelid, Johan (Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden) ,  Padykov, Leonid (Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden) ,  Gunnarsson, Iva (Department of Medicine, Rheumatology Unit, Karolinska Insti) ,  Silverman, Gregg J. ,  Svenungsson, Elisabet

Abstract AI-Helper 아이콘AI-Helper

Abstract Natural IgM autoantibodies have been proposed to convey protection from autoimmune pathogenesis. Herein, we investigated the IgM responses in 396 systemic lupus erythematosus (SLE) patients, divided into subgroups based on distinct autoantibody profiles. Depressed IgM levels were more comm...

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