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NTIS 바로가기European journal of medicinal chemistry, v.143, 2018년, pp.244 - 258
Bortolozzi, Roberta (Department of Woman's and Child's Health, University of Padova, Laboratory of Oncohematology, 35128 Padova, Italy) , Mattiuzzo, Elena (Department of Woman's and Child's Health, University of Padova, Laboratory of Oncohematology, 35128 Padova, Italy) , Dal Pra, Matteo (Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padova, Italy) , Sturlese, Mattia (Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padova, Italy) , Moro, Stefano (Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padova, Italy) , Hamel, Ernest (Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA) , Carta, Davide (Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padova, Italy) , Viola, Giampietro (Department of Woman's and Child's Health, University of Padova, Laboratory of Oncohematology, 35128 Padova, I) , Ferlin, Maria Grazia
Abstract Earlier studies had confirmed that the 7-phenylpyrroloquinolinone (7-PPyQ) nucleus was an important scaffold for new chemotherapeutic drugs targeting microtubules. For wide-ranging SARs, a series of derivatives were synthesized through a robust procedure. For comparison with the reference ...
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