[논문]Long-Term Effects of Transcranial Direct-Current Stimulation in Chronic Post-Stroke Aphasia: A Pilot Study

Vestito, Lucilla; Rosellini, Sara; Mantero, Massimo; Bandini, Fabio

doi:10.3389/fnhum.2014.00785

Long-Term Effects of Transcranial Direct-Current Stimulation in Chronic Post-Stroke Aphasia: A Pilot Study 원문보기

Frontiers in human neuroscience, v.8, 2014년, pp.785 -

Vestito, Lucilla (Rinascita Vita , Genova , Italy) , Rosellini, Sara (Rinascita Vita , Genova , Italy) , Mantero, Massimo (Rinascita Vita , Genova , Italy) , Bandini, Fabio (Department of Neurology, San Paolo Hospital , Savona , Italy)

Abstract ▼ AI-Helper

Transcranial direct-current stimulation (tDCS) has been suggested to improve language function in patients with post-stroke aphasia. Most studies on aphasic patients, however, were conducted with a very limited follow-up period, if any. In this pilot, single-blind study on chronic post-stroke aphasic patients, we aimed to verify whether or not tDCS is able to extend its beneficial effects for a longer period of time (21 weeks after the end of stimulation). Three aphasic patients underwent anodal tDCS (A-tDCS, 20 min, 1.5 mA) and sham stimulation (S-tDCS) over the left frontal (perilesional) region, coupled with a simultaneous naming training (on-line tDCS). Ten consecutive sessions (5 days per week for 2 weeks) were implemented. In the first five sessions, we used a list of 40 figures, while in the subsequent five sessions we utilized a second set of 40 figures differing in word difficulty. At the end of the stimulation period, we found a significant beneficial effect of A-tDCS (as compared to baseline and S-tDCS) in all our subjects, regardless of word difficulty, although with some inter-individual differences. In the follow-up period, the percentage of correct responses persisted significantly better until the 16th week, when an initial decline in naming performance was observed. Up to the 21st week, the number of correct responses, though no longer significant, was still above the baseline level. These results in a small group of aphasic patients suggest a long-term beneficial effect of on-line A-tDCS.

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참고문헌 (24)

Baker J. M. Rorden C. Fridriksson J. ( 2010 ). Using transcranial direct-current stimulation to treat stroke patients with aphasia . Stroke 41 , 1229 – 1236 10.1161/STROKEAHA.109.576785 20395612

상세보기
Boggio P. S. Nunes A. Rigonatti S. P. Nitsche M. A. Pascual-Leone A. Fregni F. ( 2007 ). Repeated sessions of noninvasive brain DC stimulation is associated with motor function improvement in stroke patients . Restor. Neurol. Neurosci. 25 , 123 – 129 17726271

상세보기
Bolognini N. Pascual-Leone A. Fregni F. ( 2009 ). Using non-invasive brain stimulation to augment motor training-induced plasticity . J. Neuroeng. Rehabil. 6 , 1 – 23 10.1186/1743-0003-6-8 19154570

상세보기
Fertonani A. Rosini S. Cotelli M. Rossini P. M. Miniussi C. ( 2010 ). Naming facilitation induced by transcranial direct current stimulation . Behav. Brain Res. 208 , 311 – 318 10.1016/j.bbr.2009.10.030 19883697

상세보기
Fiori V. Coccia M. Marinelli C. V. Vecchi V. Bonifazi S. Ceravolo M. G. ( 2011 ). Transcranial direct current stimulation improves word retrieval in healthy and nonfluent aphasic subjects . J. Cogn. Neurosci. 23 , 2309 – 2323 10.1162/jocn.2010.21579 20946060

상세보기
Fridriksson J. Bonilha L. Baker J. M. Moser D. Rorden C. ( 2010 ). Activity in preserved left hemisphere regions predicts anomia severity in aphasia . Cereb. Cortex 20 , 1013 – 1019 10.1093/cercor/bhp160 19687294

상세보기
Fridriksson J. Richardson J. D. Baker J. M. Rorden C. ( 2011 ). Transcranial direct current stimulation improves naming reaction time in fluent aphasia: a double-blind, sham-controlled study . Stroke 42 , 819 – 821 10.1161/STROKEAHA.110.600288 21233468

상세보기
Fritsch B. Reis J. Martinowich K. Schambra H. M. Ji Y. Cohen L. G. ( 2010 ). Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning . Neuron 66 , 198 – 204 10.1016/j.neuron.2010.03.035 20434997

상세보기
Holland R. Crinion J. ( 2012 ). Can tDCS enhance treatment of aphasia after stroke? Aphasiology 26 , 1169 – 1191 10.1080/02687038.2011.616925 23060684

상세보기
Kaplan E. Goodglass H. Weintraub S. ( 1983 ). Boston Naming Test . Philadelphia : Lea and Febiger
Khedr E. M. Shawky O. A. El-Hammady D. H. Rothwell J. C. Darwish E. S. Mostafa O. M. ( 2013 ). Effect of anodal versus cathodal transcranial direct current stimulation on stroke rehabilitation: a pilot randomized controlled trial . Neurorehabil. Neural Repair 27 , 592 – 601 10.1177/1545968313484808 23609526

상세보기
Kim H. I. Shin Y. I. L. Moon S. K. Chung G. H. Lee M. C. Kim H. G. ( 2008 ). Unipolar and continuous cortical stimulation to enhance motor and language deficit in patients with chronic stroke: report of 2 cases . Surg. Neurol. 69 , 77 – 80 10.1016/j.surneu.2006.12.055 17825377

상세보기
Luzzati C. Klaus W. De Bleser R. ( 1991 ). Aachener Aphasie Test Versione Italiana . Firenze : Giunti Organizzazioni Speciali
Marangolo P. Fiori V. Calpagnano M. A. Campana S. Razzano C. Caltagirone C. ( 2013 ). tDCS over the left inferior frontal cortex improve speech production in aphasia . Front. Hum. Neurosci. 7 : 539 10.3389/fnhum.2013.00539 24046740

상세보기
Marangolo P. Marinelli C. V. Bonifazi S. Fiori V. Ceravolo M. G. Provinciali L. ( 2011 ). Electrical stimulation over the left inferior frontal gyrus (IFG) determines long-term effects in the recovery of speech apraxia in three chronic aphasics . Behav. Brain Res. 225 , 498 – 504 10.1016/j.bbr.2011.08.008 21856336

상세보기
Monti A. Cogiamanian F. Marceglia S. Ferrucci F. Mameli F. Mrakic-Sposta S. ( 2008 ). Improved naming after transcranial direct current stimulation in aphasia . J. Neurol. Neurosurg. Psychiatr. 79 , 451 – 453 10.1136/jnnp.2007.135277 18096677

상세보기
Monti A. Ferrucci R. Fumagalli M. Mameli F. Cogiamanian F. Ardolino G. ( 2013 ). Transcranial direct current stimulation (tDCS) and language . J. Neurol. Neurosurg. Psychiatr. 84 , 832 – 842 10.1136/jnnp-2012-302825 23138766

상세보기
Nitsche M. A. Fricke K. Henschke U. Schlitterlau A. Liebetanz D. Lang N. ( 2003 ). Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans . J. Physiol. 553 , 293 – 301 10.1113/jphysiol.2003.049916 12949224

상세보기
Nitsche M. A. Paulus W. ( 2000 ). Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation . J. Physiol. 527 , 633 – 639 10.1111/j.1469-7793.2000.t01-1-00633.x 10990547

상세보기
Paulus W. ( 2003 ). Transcranial direct current stimulation (tDCS) . Suppl. Clin. Neurophysiol. 56 , 249 – 254 10.1016/S1567-424X(09)70229-6 14677402

상세보기
Poreisz C. Boros K. Antal A. Paulus W. ( 2007 ). Safety aspects of transcranial direct current stimulation concerning healthy subjects and patients . Brain Res. Bull. 72 , 208 – 214 10.1016/j.brainresbull.2007.01.004 17452283

상세보기
Reis J. Schambra H. M. Cohen L. G. Buch E. R. Fritsch B. Zarahn E. ( 2009 ). Noninvasive cortical stimulation enhances motor skill acquisition over multiple days through an effect on consolidation . Proc. Natl. Acad. Sci. U.S.A. 106 , 1590 – 1595 10.1073/pnas.0805413106 19164589

상세보기
Thompson C. K. Shapiro L. C. ( 2007 ). Complexity in the treatment of syntactic deficits . Am. J. Speech Lang. Pathol. 16 , 3 – 5 10.1044/1058-0360(2007/002) 17329670

상세보기
Volpato C. Cavinato M. Piccione F. Garzon M. Meneghello F. Birbaumer N. ( 2013 ). Transcranial direct current stimulation (tDCS) of Broca’s area in chronic aphasia: a controlled outcome study . Behav. Brain Res. 247 , 211 – 216 10.1016/j.bbr.2013.03.029 23538068

상세보기

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Long-Term Effects of Transcranial Direct-Current Stimulation in Chronic Post-Stroke Aphasia: A Pilot Study 원문보기

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