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MYC Is Activated by USP2a-Mediated Modulation of MicroRNAs in Prostate Cancer 원문보기

Cancer discovery, v.2 no.3, 2012년, pp.236 - 247  

Benassi, Barbara ,  Flavin, Richard ,  Marchionni, Luigi ,  Zanata, Silvio ,  Pan, Yunfeng ,  Chowdhury, Dipanjan ,  Marani, Marina ,  Strano, Sabrina ,  Muti, Paola ,  Blandino, Giovanni ,  Loda, Massimo

Abstract AI-Helper 아이콘AI-Helper

AbstractUbiquitin-specific protease 2a (USP2a) is overexpressed in almost half of human prostate cancers and c-Myc is amplified in one third of these tumor types. Transgenic MYC expression drives invasive adenocarcinomas in the murine prostate. We show that overexpression of USP2a downregulates a se...

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