최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Journal of veterinary science, v.19 no.1, 2018년, pp.129 - 135
Lee, Chang-Min (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05030, Korea.) , Han, Jae-Ik (Laboratory of Wildlife Diseases, College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea.) , Kang, Min-Hee (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05030, Korea.) , Kim, Seung-Gon (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05030, Korea.) , Park, Hee-Myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05030, Korea.)
Degenerative mitral valve disease (DMVD) is the most commonly acquired cardiac disease in dogs. This study evaluated the relationship between genetic variations in the serotonin transporter (SERT) gene of Maltese dogs and DMVD. Genomic DNA was extracted from blood samples collected from 20 client-ow...
1 Adzhubei IA Schmidt S Peshkin L Ramensky VE Gerasimova A Bork P Kondrashov AS Sunyaev SR A method and server for predicting damaging missense mutations Nat Methods 2010 7 248 249 20354512
2 Arndt JW Reynolds CA Singletary GE Connolly JM Levy RJ Oyama MA Serum serotonin concentrations in dogs with degenerative mitral valve disease J Vet Intern Med 2009 23 1208 1213 19709352
3 Atkins C Bonagura J Ettinger S Fox P Gordon S Haggstrom J Hamlin R Keene B Luis-Fuentes V Stepien R Guidelines for the diagnosis and treatment of canine chronic valvular heart disease J Vet Intern Med 2009 23 1142 1150 19780929
4 Aupperle H Disatian S Pathology, protein expression and signaling in myxomatous mitral valve degeneration: comparison of dogs and humans J Vet Cardiol 2012 14 59 71 22364722
5 Bhardwaj R Mukhopadhyay CS Deka D Verma R Dubey PP Arora JS Biocomputational analysis of evolutionary relationship between toll-like receptor and nucleotide-binding oligomerization domain-like receptors genes Vet World 2016 9 1218 1228 27956772
6 Black A French AT Dukes-McEwan J Corcoran BM Ultrastructural morphologic evaluation of the phenotype of valvular interstitial cells in dogs with myxomatous degeneration of the mitral valve Am J Vet Res 2005 66 1408 1414 16173485
7 Borgarelli M Buchanan JW Historical review, epidemiology and natural history of degenerative mitral valve disease J Vet Cardiol 2012 14 93 101 22386588
8 Borgarelli M Zini E D'Agnolo G Tarducci A Santilli RA Chiavegato D Tursi M Prunotto M Häggström J Comparison of primary mitral valve disease in German Shepherd dogs and in small breeds J Vet Cardiol 2004 6 27 34 19083307
9 Corcoran BM Black A Anderson H McEwan JD French A Smith P Devine C Identification of surface morphologic changes in the mitral valve leaflets and chordae tendineae of dogs with myxomatous degeneration Am J Vet Res 2004 65 198 206 14982036
10 Cremer SE Moesgaard SG Rasmussen CE Zois NE Falk T Reimann MJ Cirera S Aupperle H Oyama MA Olsen LH Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease Res Vet Sci 2015 100 197 206 25843893
11 Darmon M Al Awabdh S Emerit MB Masson J Insights into serotonin receptor trafficking: cell membrane targeting and internalization Prog Mol Biol Transl Sci 2015 132 97 126 26055056
12 Disatian S Orton EC Autocrine serotonin and transforming growth factor beta 1 signaling mediates spontaneous myxomatous mitral valve disease J Heart Valve Dis 2009 18 44 51 19301552
13 Drögemüller M Jagannathan V Becker D Drögemüller C Schelling C Plassais J Kaerle C Dufaure de Thomas A Müller EJ Welle MM Roosje P Leeb T A mutation in the FAM83G gene in dogs with hereditary footpad hyperkeratosis (HFH) PLoS Genet 2014 10 e1004370 24832243
14 Elangbam CS Job LE Zadrozny LM Barton JC Yoon LW Gates LD Slocum N 5-hydroxytryptamine (5HT)-induced valvulopathy: compositional valvular alterations are associated with 5HT2B receptor and 5HT transporter transcript changes in Sprague-Dawley rats Exp Toxicol Pathol 2008 60 253 262 18511249
15 Greenberg BD Tolliver TJ Huang SJ Li Q Bengel D Murphy DL Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets Am J Med Genet 1999 88 83 87 10050973
16 Gustafsson BI Tømmerås K Nordrum I Loennechen JP Brunsvik A Solligård E Fossmark R Bakke I Syversen U Waldum H Long-term serotonin administration induces heart valve disease in rats Circulation 2005 111 1517 1522 15781732
17 Heils A Teufel A Petri S Stöber G Riederer P Bengel D Lesch KP Allelic variation of human serotonin transporter gene expression J Neurochem 1996 66 2621 2624 8632190
18 Källberg M Wang H Wang S Peng J Wang Z Lu H Xu J Template-based protein structure modeling using the RaptorX web server Nat Protoc 2012 7 1511 1522 22814390
19 Lesch KP Bengel D Heils A Sabol SZ Greenberg BD Petri S Benjamin J Müller CR Hamer DH Murphy DL Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 1996 274 1527 1531 8929413
20 Levy FO Qvigstad E Krobert KA Skomedal T Osnes JB Effects of serotonin in failing cardiac ventricle: signalling mechanisms and potential therapeutic implications Neuropharmacology 2008 55 1066 1071 18675829
21 Mekontso-Dessap A Brouri F Pascal O Lechat P Hanoun N Lanfumey L Seif I Benhaiem-Sigaux N Kirsch M Hamon M Adnot S Eddahibi S Deficiency of the 5-hydroxytryptamine transporter gene leads to cardiac fibrosis and valvulopathy in mice Circulation 2006 113 81 89 16380550
22 Morris GM Huey R Lindstrom W Sanner MF Belew RK Goodsell DS Olson AJ AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility J Comput Chem 2009 30 2785 2791 19399780
23 Olsen LH Fredholm M Pedersen HD Epidemiology and inheritance of mitral valve prolapse in Dachshunds J Vet Intern Med 1999 13 448 456 10499729
24 Orton EC Lacerda CM MacLea HB Signaling pathways in mitral valve degeneration J Vet Cardiol 2012 14 7 17 22364692
25 Oyama MA Chittur SV Genomic expression patterns of mitral valve tissues from dogs with degenerative mitral valve disease Am J Vet Res 2006 67 1307 1318 16881841
26 Parker HG Kilroy-Glynn P Myxomatous mitral valve disease in dogs: does size matter J Vet Cardiol 2012 14 19 29 22356836
27 Pedersen HD Lorentzen KA Kristensen BO Echocardiographic mitral valve prolapse in cavalier King Charles spaniels: epidemiology and prognostic significance for regurgitation Vet Rec 1999 144 315 320 10212505
28 Rothman RB Baumann MH Therapeutic and adverse actions of serotonin transporter substrates Pharmacol Ther 2002 95 73 88 12163129
29 Sali A Blundell TL Comparative protein modelling by satisfaction of spatial restraints J Mol Biol 1993 234 779 815 8254673
30 Scruggs SM Disatian S Orton EC Serotonin transmembrane transporter is down-regulated in late-stage canine degenerative mitral valve disease J Vet Cardiol 2010 12 163 169 21036114
31 Sutcliffe JS Delahanty RJ Prasad HC McCauley JL Han Q Jiang L Li C Folstein SE Blakely RD Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors Am J Hum Genet 2005 77 265 279 15995945
32 van den Berg L Kwant L Hestand MS van Oost BA Leegwater PA Structure and variation of three canine genes involved in serotonin binding and transport: the serotonin receptor 1A gene (htr1A), serotonin receptor 2A gene (htr2A), and serotonin transporter gene (slc6A4) J Hered 2005 96 786 796 16251523
33 Waraphan T Aekkapot C Panpanga S Pranom P Effect of single mutagenesis on the binding pocket of canine estrogen receptor alpha: structure and binding affinity Adv Mod Oncol Res 2016 2 116 121
34 Zhao H Yang Y Zhou Y Highly accurate and high-resolution function prediction of RNA binding proteins by fold recognition and binding affinity prediction RNA Biol 2011 8 988 996 21955494
※ AI-Helper는 부적절한 답변을 할 수 있습니다.