[특허]Structured bioerodible drug delivery device

Structured bioerodible drug delivery device 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61K-009/22 A61K-009/50 A61K-009/52 A61K-009/54
출원번호	US-0517982 (1974-10-25)
발명자 / 주소	Michaels Alan S. (Atherton CA)
출원인 / 주소	Alza Corporation (Palo Alto CA 02)
인용정보	피인용 횟수 : 105 인용 특허 : 0

초록 ▼

A drug delivery device for the continuous and controlled administration of a predetermined therapeutically effective dosage of eye drug to the eye of a mamallian patient over a prolonged period of time. The device meters the flow of polylactic acid polymer micro-encapsulated eye drug by means of a drug release rate controlling material comprised of an anionic polyvalent metal cation cross-linked polyelectrolyte. The device bioerodes in the biological environment of the patient concurrently with the dispensing or at a point in time after the dispensing of the therapeutically desired amount of drug.

대표청구항 ▼

A delivery device for the sustained administration of a predetermined dosage of an ophthalmic drug to the eye of a mammalian patient comprising (1) an inner reservoir comprised of a biodegradable material that degrades to innocuous products in response to the biological ocular environment of the patient, said reservoir containing an ophthalmic drug formulation confined therein, and (2) an outer membrane surrounding the inner reservoir, the membrane permeable to the passage of ophthalmic drug, but at a lower rate than through the inner reservoir, the membrane formed from drug release rate controlling bioerodible material consisting of a polyvalent metal ion cross-linked anionic polyelectrolyte, said ion a member selected from the group consisting of aluminum, barium, cadmium, calcium, copper, iron, zinc and mixtures thereof, said polyelectrolyte a member selected from the group consisting of cellulose, hemicellulose, starch, polystyrene sulfonic acid, polyvinyl sulfonic acid, polyvinyl methylol sulfonic acid, polyacrylic acid, polymethacrylic acid, acRylic copolymers, methacrylic copolymers, polyvinyl alcohol, polyvinyl chloride, glycans and polysaccharides, which outer membrane bioerodes in the eye of the patient in response to the biological environment therein by a process of polyvalent metal ion displacement by noncross-linking ions present in the eye, and wherein when in the ocular environment the membrane continuously meters the flow of a therapeutically effective amount of ophthalmic drug from the reservoir to the eye of the patient at a controlled and continuous rate over a prolonged period of time.

이 특허를 인용한 특허 (105)

Gallop, Mark A., Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use.
상세보기
Zerangue, Noa; Jandeleit, Bernd; Li, Yunxiao; Gallop, Mark A., Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use.
상세보기
Zerangue, Noa; Jandeleit, Bernd; Li, Yunxiao; Gallop, Mark A., Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use.
상세보기
Zerangue, Noa; Jandeleit, Bernd; Li, Yunxiao; Gallop, Mark A., Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use.
상세보기
Zerangue,Noa; Jandeleit,Bernd; Li,Yunxiao; Gallop,Mark A., Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use.
상세보기
Gallop, Mark A.; Xu, Feng; Phan, Thu; Dilip, Usha; Peng, Ge, Acyloxyalkyl carbamate prodrugs, methods of synthesis and use.
상세보기
Gallop, Mark A.; Xu, Feng; Phan, Thu; Dilip, Usha; Peng, Ge, Acyloxyalkyl carbamate prodrugs, methods of synthesis and use.
상세보기
Gallop, Mark A.; Yao, Fenmei; Ludwikow, Maria J.; Phan, Thu; Peng, Ge, Acyloxyalkyl carbamate prodrugs, methods of synthesis and use.
상세보기
Gallop, Mark A.; Yao, Fenmei; Ludwikow, Maria J.; Phan, Thu; Peng, Ge, Acyloxyalkyl carbamate prodrugs, methods of synthesis and use.
상세보기
Gallop,Mark A.; Yao,Fenmei; Ludwikow,Maria J.; Phan,Thu; Peng,Ge, Acyloxyalkyl carbamate prodrugs, methods of synthesis and use.
상세보기
Gallop,Mark A.; Yao,Fenmei; Ludwikow,Maria J.; Phan,Thu; Peng,Ge, Acyloxyalkyl carbamate prodrugs, methods of synthesis and use.
상세보기
Gallop,Mark A., Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use.
상세보기
Gallop, Mark; Cundy, Kenneth C.; Scheuerman, Randall A.; Barrett, Ronald W.; Zerangue, Noa, Amino acid conjugates providing for sustained systemic concentrations of GABA analogues.
상세보기
Gallop,Mark; Cundy,Kenneth C.; Scheuerman,Randall A.; Barrett,Ronald W.; Zerangue,Noa, Amino acid conjugates providing for sustained systemic concentrations of GABA analogues.
상세보기
Alster, Yair; de Juan, Jr., Eugene; Reich, Cary J.; Boyd, Stephen; Sierra, David; Alejandro, Jose D.; Macfarlane, K. Angela; Sutton, Douglas, Anterior segment drug delivery.
상세보기
Alster, Yair; de Juan, Jr., Eugene; Reich, Cary J.; Boyd, Stephen; Sierra, David; Alejandro, Jose D.; Macfarlane, K. Angela; Sutton, Douglas, Anterior segment drug delivery.
상세보기
Robinson Joseph R. (Madison WI), Bioadhesive compositions and methods of treatment therewith.
상세보기
Wong Vernon G. (Rockville MD), Biodegradable ocular implants.
상세보기
Xiang,Jia Ning; Gallop,Mark A.; Cundy,Kenneth C.; Li,Jianhua; Xu,Feng; Zhou,Cindy X.; Bhat,Laxminarayan, Carbidopa prodrugs and derivatives, and compositions and uses thereof.
상세보기
Xiang, Jia-Ning; Zhou, Cindy X.; Yao, Fenmei; Nguyen, Mark Q., Catechol protected levodopa diester prodrugs, compositions, and methods of use.
상세보기
Xiang, Jia-Ning; Zhou, Cindy X.; Yao, Fenmei; Nguyen, Mark Q., Catechol protected levodopa diester prodrugs, compositions, and methods of use.
상세보기
Graham ; Jr. Joseph A. (Milo IA) Hibbs Clair R. (Albuquerque NM), Composition for prophylactic treatment of pinkeye.
상세보기
Castleberry, Steven A.; Hammond, Paula T., Compositions and methods for nucleic acid delivery.
상세보기
Smith, Renee Chivon; Hammond-Cunningham, Paula T., Controlled delivery of bioactive agents from decomposable films.
상세보기
Drake Cyril F. (Harlow GBX) Arch Alfred J. (Ongar GBX), Controlled release system.
상세보기
Leahy, Charles D.; Ellis, Edward J., Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation.
상세보기
Gupta Suneel K. ; Guinta Diane R. ; Christopher Carol A. ; Saks Samuel R., Dosage form and method for administering drug.
상세보기
Gardner David L. (Bellville OH), Dual Microcapsules and process for their preparation.
상세보기
Nun, Joshua Ben, Eye wall anchored fixtures.
상세보기
Cundy, Kenneth C.; Sastry, Srikonda; Leung, Manshiu; Kadri, Balaji V.; Stach, Paul E., GABA analog prodrug sustained release oral dosage forms.
상세보기
Cundy, Kenneth C.; Sastry, Srikonda; Leung, Manshiu; Kadri, Balaji V.; Stach, Paul E., GABA analog prodrug sustained release oral dosage forms.
상세보기
Xiang, Jia-Ning; Zhou, Cindy X.; Yao, Fenmei; Nguyen, Mark Q., Levodopa dimethyl-substituted diester prodrugs compositions, and methods of use.
상세보기
Xiang, Jia-Ning; Zhou, Cindy X.; Yao, Fenmei; Nguyen, Mark Q., Levodopa dimethyl-substituted diester prodrugs, compositions, and methods of use.
상세보기
Karaborni, Sami; Leung, Manshiu; Mao, Chen; Thalladi, Venkat, Levodopa prodrug mesylate hydrate.
상세보기
Karaborni, Sami; Leung, Manshiu; Mao, Chen; Thalladi, Venkat R., Levodopa prodrug mesylate hydrate.
상세보기
Xiang, Jia Ning; Dai, Xuedong; Zhou, Cindy X.; Li, Jianhua; Nguyen, Mark Q., Levodopa prodrug mesylate, compositions thereof, and uses thereof.
상세보기
Xiang, Jia-Ning; Dai, Xuedong; Zhou, Cindy X.; Li, Jianhua; Nguyen, Mark Q., Levodopa prodrug mesylate, compositions thereof, and uses thereof.
상세보기
Xiang, Jia-Ning; Dai, Xuedong; Zhou, Cindy X.; Li, Jianhua; Nguyen, Mark Q., Levodopa prodrug mesylate, compositions thereof, and uses thereof.
상세보기
Xiang, Jia-Ning; Dai, Xuedong; Zhou, Cindy X.; Li, Jianhua; Nguyen, Mark Q., Levodopa prodrug mesylate, compositions thereof, and uses thereof.
상세보기
Xiang, Jia Ning; Gallop, Mark A.; Zhou, Cindy X.; Nguyen, Mark; Dai, Xuedong; Li, Jianhua; Cundy, Kenneth C.; Jumbe, Nelson L., Levodopa prodrugs, and compositions and uses thereof.
상세보기
Xiang, Jia-Ning; Gallop, Mark A.; Zhou, Cindy X.; Nguyen, Mark; Dai, Xuedong; Li, Jianhua; Cundy, Kenneth C.; Jumbe, Nelson L., Levodopa prodrugs, and compositions and uses thereof.
상세보기
Xiang, Jia-Ning; Gallop, Mark A.; Zhou, Cindy X.; Nguyen, Mark; Dai, Xuedong; Li, Jianhua; Cundy, Kenneth C.; Jumbe, Nelson L., Levodopa prodrugs, and compositions and uses thereof.
상세보기
Xiang,Jia Ning; Gallop,Mark A.; Zhou,Cindy X.; Nguyen,Mark; Dai,Xuedong; Li,Jianhua; Cundy,Kenneth C., Levodopa prodrugs, and compositions and uses thereof.
상세보기
Xiang,Jia Ning; Gallop,Mark A.; Zhou,Cindy X.; Nguyen,Mark; Dai,Xuedong; Li,Jianhua; Cundy,Kenneth C.; Jumbe,Nelson L., Levodopa prodrugs, and compositions and uses thereof.
상세보기
Ellis, Edward J.; Ellis, Jeanne Y., Method for forming an ocular drug delivery device.
상세보기
Guittard George V. ; Jao Francisco ; Marks Susan M. ; Kidney David J. ; Gumucio Fernando E., Method for the management of incontinence.
상세보기
Guittard, George V.; Jao, Francisco; Marks, Susan M.; Kidney, David J.; Gumucio, Fernando E., Method for the management of incontinence.
상세보기
Martins Agusto B. (Palo Alto CA) Amkraut Alfred A. (Palo Alto CA), Method of coadministering an antigen and an immunopotentiator.
상세보기
Gupta, Suneel K.; Guinta, Diane R.; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G., Methods and devices for providing prolonged drug therapy.
상세보기
Gupta, Suneel K.; Guinta, Diane R.; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G., Methods and devices for providing prolonged drug therapy.
상세보기
Gupta, Suneel K.; Guinta, Diane R; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G., Methods and devices for providing prolonged drug therapy.
상세보기
Lam, Andrew C.; Shivanand, Padmaja; Ayer, Atul D.; Hatamkhany, Zahedeh; Gupta, Suneel K.; Guinta, Diane R.; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G.; Wright, Jeri D.; Weyers, Richar, Methods and devices for providing prolonged drug therapy.
상세보기
Lam, Andrew C.; Shivanand, Padmaja; Ayer, Atul D.; Hatamkhany, Zahedeh; Gupta, Suneel K.; Guinta, Diane R.; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G.; Wright, Jeri D.; Weyers, Richard G., Methods and devices for providing prolonged drug therapy.
상세보기
Lam, Andrew C.; Shivanand, Padmaja; Ayer, Atul D.; Weyers, Richard G.; Gupta, Suneel K.; Guinta, Diane R.; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G.; Wright, Jeri D.; Hatamkhany, Zah, Methods and devices for providing prolonged drug therapy.
상세보기
Lam, Andrew C.; Shivanand, Padmaja; Ayer, Atul D; Hatamkhany, Zahedeh; Weyers, Richard G; Gupta, Suneel K.; Guinta, Diane R; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G.; Wright, Jeri D., Methods and devices for providing prolonged drug therapy.
상세보기
Yam, Nyomi V.; Reyes, Iran; Davar, Nipun; Ayer, Atul D.; Lee, Julie; Seroff, Sonya; Gupta, Suneel K.; Sathyan, Gayatri, Methods and dosage forms for controlled delivery of paliperidone and risperidone.
상세보기
Raillard,Stephen P.; Zhou,Cindy X.; Yao,Fenmei; Manthati,Suresh Kumar; Xiang,Jia Ning; Gallop,Mark A., Methods for synthesis of acyloxyalkyl derivatives of GABA analogs.
상세보기
Raillard,Stephen P.; Zhou,Cindy X.; Yao,Fenmei; Manthati,Suresh Kumar; Xiang,Jia Ning; Gallop,Mark A., Methods for synthesis of acyloxyalkyl derivatives of GABA analogs.
상세보기
Wood, Kris C.; Chuang, Helen F.; Batten, Robert D.; Lynn, David M.; Hammond Cunningham, Paula T., Methods of making decomposable thin films of polyelectrolytes and uses thereof.
상세보기
Raillard, Stephen P.; Mann, Adam; Manthati, Suresh K.; Scheuerman, Randall A.; Estrada, Tono; Nguyen, Mark Q.; Zhou, Cindy X, Methods of synthesizing a levodopa ester prodrug.
상세보기
D'Souza, Martin J., Microencapsulated compounds and method of preparing same.
상세보기
D'Souza,Martin J., Microencapsulated materials and method of making same.
상세보기
D'Souza, Martin J., Nanospheres encapsulating bioactive material and method for formulation of nanospheres.
상세보기
D'Souza, Martin J., Nanospheres encapsulating bioactive material and method for formulation of nanospheres.
상세보기
Hammond, Paula T.; Lee, Jong Bum; Roh, Young Hoon, Nucleic acid particles, methods and use thereof.
상세보기
Leahy, Charles D.; Labombard, Denis, Ocular drug delivery device.
상세보기
Leahy, Charles D.; Labombard, Denis, Ocular drug delivery device.
상세보기
Leahy, Charles D.; Labombard, Denis, Ocular drug delivery device.
상세보기
de Juan, Jr., Eugene; Alster, Yair; Reich, Cary J.; MacFarlane, K. Angela; Chang, Janelle; Alejandro, Jose D., Ocular insert apparatus and methods.
상세보기
de Juan, Jr., Eugene; Alster, Yair; Reich, Cary J.; MacFarlane, K. Angela; Chang, Janelle; Boyd, Stephen; Sierra, David; Alejandro, Jose D.; Sutton, Douglas; Gould, Alexander J., Ocular insert apparatus and methods.
상세보기
de Juan, Jr., Eugene; Alster, Yair; Reich, Cary J.; Macfarlane, K. Angela; Chang, Janelle; Boyd, Stephen; Sierra, David; Alejandro, Jose D.; Sutton, Douglas; Gould, Alexander J., Ocular insert apparatus and methods.
상세보기
Shell John W. (Hillsborough CA) Gale Robert M. (Mountain View CA), Ocular insert housing steroid in two different therapeutic forms.
상세보기
Shell John W. (Hillsborough CA) Gale Robert M. (Mountain View CA), Ocular preparation housing steroid in two different therapeutic forms.
상세보기
Cohan Bruce E. ; Diamond Howard, Ophthalmic insert and method for sustained release of medication to the eye.
상세보기
Rubin, Anne Brody; Alster, Yair; Reich, Cary J., Ophthalmic system for sustained release of drug to eye.
상세보기
Cundy, Kenneth C.; Gallop, Mark A., Orally administered dosage forms of GABA analog prodrugs having reduced toxicity.
상세보기
Mao, Chen; Pargaonkar, Nikhil; Maurer, Laura E.; Ma, Sarina Grace Harris, Pharmaceutical compositions and oral dosage forms of a levodopa prodrug and methods of use.
상세보기
Gao,Qingzhi; Gallop,Mark A.; Xiang,Jia Ning, Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use.
상세보기
Jenkins, Thomas E., Polysubunit opioid prodrugs resistant to overdose and abuse.
상세보기
Jenkins, Thomas E., Polysubunit opioid prodrugs resistant to overdose and abuse.
상세보기
Gardner David L. (Bellville OH), Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or e 상세보기

IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표IPC 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 공고번호, 공고일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표출원인, 출원인국적, 출원인주소, 발명자, 발명자E, 발명자코드, 발명자주소, 발명자 우편번호, 발명자국적, 대표IPC, IPC코드, 요약, 미국특허분류, 대리인주소, 대리인코드, 대리인(한글), 대리인(영문), 국제공개일자, 국제공개번호, 국제출원일자, 국제출원번호, 우선권, 우선권주장일, 우선권국가, 우선권출원번호, 원출원일자, 원출원번호, 지정국, Citing Patents, Cited Patents
저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Structured bioerodible drug delivery device 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

이 특허를 인용한 특허 (105)

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

Structured bioerodible drug delivery device 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

이 특허를 인용한 특허 (105)

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트