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특허 상세정보

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Fluorescence quenching with immunological pairs in immunoassays

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) G01N-021/00    G01N-033/16   
미국특허분류(USC) 424/12 ; 23/230B ; 195/1035 ; R ; 260/112B
출원번호 US-0591386 (1975-06-30)
발명자 / 주소
  • Ullman Edwin F. (Atherton CA) Schwarzberg Moshe (Palo Alto CA)
출원인 / 주소
  • Syva Company (Palo Alto CA 02)
인용정보 피인용 횟수 : 792  인용 특허 : 1
초록
▼

Immunoassays employing antibodies and a fluorescer-quencher (F-Q) chromophoric pair, wherein one or both of the chromophoric pair are bonded to antibodies. Depending on the particular ligand of interest, various reagent combinations can be employed, where the amount of quenching is directly related to the amount of ligand present in the assay medium. In carrying out the assay, the unknown and antibody specific for the ligand of interest to which is bound one of the F-Q pair, are combined in an aqueous buffered medium. Depending on the protocol, different...

대표
청구항
▼

A method for determining in an assay solution, the presence of a ligand in an unknown suspected of containing said ligand, said ligand having at least one epitopic site, wherein two chromophores, Ch1 and Ch2, which form a fluorescer-quencher pair are employed as reagents, whereby in said assay solution the amount of fluorescer brought within quenching distance of said quencher is affected by the presence of ligand, which comprises: A. combining in an aqueous buffered medium to form an assay solution; 1. said unknown; 2. a source of Ch1, as Ch1 covalently...

이 특허에 인용된 특허 (1)

  1. Rubenstein Kenneth Edward (Palo Alto CA) Leute Richard K. (Sunnyvale CA), Antibody steric hindrance immunoassay with two antibodies.

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  344. Fima, Udi Eyal; Hart, Gili, Long-acting polypeptides and methods of producing and administering same.
  345. Fares, Fuad; Fima, Udi Eyal, Long-acting polypeptides and methods of producing same.
  346. Fares, Fuad; Fima, Udi Eyal, Long-acting polypeptides and methods of producing same.
  347. Fares, Fuad; Fima, Udi Eyal, Long-acting polypeptides and methods of producing same.
  348. Fares, Fuad; Fima, Udi Eyal, Long-acting polypeptides and methods of producing same.
  349. Fares, Fuad; Fima, Udi Eyal, Long-acting polypeptides and methods of producing same.
  350. Fares, Fuad; Fima, Udi Eyal, Long-acting veterinary polypeptides and methods of producing and administering same.
  351. Terpetschnig, Ewald A.; Patsenker, Leonid D.; Oswald, Bernhard, Luminescent compounds.
  352. Terpetschnig,Ewald A.; Patsenker,Leonid D.; Tatarets,Anatoliy, Luminescent compounds.
  353. Terpetschnig,Ewald A.; Tatarets,Anatoliy; Galkina,Olga; Fedyunyaeva,Iryna; Patsenker,Leonid, Luminescent compounds.
  354. Zuk, Robert F., Luminescent immunoassays for quantitating analytes having a wide concentration range.
  355. Bard Allen J. ; Whitesides George M., Luminescent metal chelate labels and means for detection.
  356. Zuk, Robert F.; Tan, Hong, Luminescent polymer cyclic amplification.
  357. Zuk, Robert F.; Tan, Hong, Luminescent polymer cyclic amplification.
  358. Litman David J. (Cupertino CA) Harel Zvi (Haifa CA ILX) Ullman Edwin F. (Atherton CA), Macromolecular fluorescent quencher particle in specific receptor assays.
  359. Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Mammalian cells that have increased proliferative capacity.
  360. Alverdy, John C., Materials and methods for preventing and treating microbe-mediated epithelial disorders.
  361. Alitalo, Kari; Jeltsch, Markku M., Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins.
  362. Bohmer, Ralph M., Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood.
  363. Sharat Singh ; Edwin F. Ullman, Metal chelate containing compositions for use in chemiluminescent assays.
  364. Singh Sharat ; Ullman Edwin F., Metal chelate containing compositions for use in chemiluminescent assays.
  365. Singh, Sharat; Ullman, Edwin F., Metal chelate containing compositions for use in chemiluminescent assays.
  366. Singh,Sharat; Ullman,Edwin F., Metal chelate containing compositions for use in chemiluminescent assays.
  367. Hansen W. Peter (Middleboro MA) Hoffman Robert A. (Mansfield MA), Method and apparatus for automated identification and enumeration of specified blood cell subclasses.
  368. Kraus Michael,DEX ; Schelp Carsten,DEX ; Wiegand Andreas,DEX, Method and diagnostic agent for hemostasis diagnosis.
  369. Kraus, Michael; Schelp, Carsten; Wiegand, Andreas, Method and diagnostic agent for hemostasis diagnosis.
  370. Michael Kraus DE; Carsten Schelp DE; Andreas Wiegand DE, Method and diagnostic agent for hemostasis diagnosis.
  371. Sun, Gang; Ramakrishnan, Ramesh; Jones, Robert C., Method and program for performing baseline correction of amplification curves in a PCR experiment.
  372. Tsuji, Yasuhiro; Kamisango, Keiichi; Otsuka, Mitsuo, Method for assay of analyte by adjustment of chemiluminescence.
  373. Neufeld, Gera; Akiri, Gal; Vadasz, Zahava; Gengrinovitch, Stela, Method for assessing metastatic properties of breast cancer.
  374. Farina, Peter R.; Golke, James R., Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays.
  375. Sammons, Robert D.; Ivashuta, Sergey; Liu, Hong; Wang, Dafu; Feng, Paul C. C.; Kouranov, Andrei Y.; Andersen, Scott E., Method for controlling herbicide-resistant plants.
  376. Mehta Harshvardhan B. ; Kurn Nurith, Method for detecting analytes.
  377. Young Charles Y. F. ; Tindall Donald J. ; Klee George G., Method for detection of breast cancer.
  378. Kevin M. Slawin ; Donald J. Tindall ; Charles Y. F. Young ; Mohammad Saeed Saedi ; Abhay Kumar ; Harry G. Rittenhouse ; Robert L. Wolfert, Method for detection of micrometastatic prostate cancer.
  379. Cech, Thomas R.; Lingner, Joachim; Nakamura, Toru M.; Chapman, Karen B.; Morin, Gregg B.; Harley, Calvin B.; Andrews, William H., Method for eliciting an immune response to human telomerase reverse transcriptase.
  380. Adair, Charles David, Method for extending pregnancy by reducing intraventricular hemorrhaging in patients exhibiting at least one symptom of preeclampsia and eclampsia.
  381. Schmitz, Juergen; Buck, David William; Dzionek, Andrzej, Method for isolating BDCA-4+ dendritic cells.
  382. Nishino Tomoyoshi (Tokushima JPX), Method for preparing a pancreatic glucagon specific antibody.
  383. Larsen, Niels Erik; Søe, Jørn Borch, Method for producing ultra-heat treatment milk.
  384. Wassell, Paul; Søe, Jørn Borch; Mikkelsen, Jørn Dalgaard; Kristensen, Anna Cecilie Jentoft, Method for reducing 1,2-diglyceride content of an edible oil.
  385. Bardat, Annie; Begin, Edith; Khandoudi, Nassirah; Just, Olivier; Chtourou, Sami; Schmitthaeusler, Roland, Method for stabilising an immunoglobulin G composition in liquid form.
  386. Romeo, Tony, Method of altering the expression of csrB to modify the properties of a cell.
  387. Tsuji Yasuhiro,JPX ; Kamisango Keiichi,JPX ; Otsuka Mitsuo,JPX, Method of assaying specimen substance by controlling dose of chemiluminescence.
  388. Bloomgren, Gary Lewis; Bozic, Carmen; Lee, Sophia; Pace, Amy; Plavina, Tatiana; Subramanyam, Meena, Method of assessing risk of PML.
  389. Pease John S. (Los Altos CA) Kirakossian Hrair (San Jose CA) Wagner Daniel B. (Sunnyvale CA) Ullman Edwin F. (Atherton CA), Method of calibration with photoactivatable chemiluminescent matrices.
  390. Kappel, Andreas; Rechner, Andreas; Stephan, Sina; Wissel, Thomas, Method of determining inhibitors of coagulation.
  391. Williams, Peter, Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  392. Williams, Peter, Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  393. Williams, Peter, Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  394. Williams, Peter, Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  395. Williams, Peter; Taylor, Thomas J.; Williams, Daniel J. B.; Gould, Ian; Hayes, Mark A., Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  396. Williams, Peter; Taylor, Thomas J.; Williams, Daniel J. B.; Gould, Ian; Hayes, Mark A., Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  397. Williams, Peter; Taylor, Thomas J.; Williams, Daniel J. B.; Gould, Ian; Hayes, Mark A., Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  398. Williams, Peter; Williams, Daniel J. B.; Bloom, Linda; Taylor, Thomas J., Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  399. Williams, Peter; Williams, Daniel J. B.; Bloom, Linda; Taylor, Thomas J., Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  400. Roth, Mark, Method of diagnosing autoimmune disease.
  401. Merchav, Shoshana; Meretski, Shai, Method of expanding undifferentiated hemopoietic stem cells.
  402. Bojsen, Kirsten; Poulsen, Charlotte Horsman; Soe, Jorn Borch, Method of improving dough and bread quality.
  403. Hershkovitz, Oren; Bar-Ilan, Ahuva, Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides.
  404. Amos Lynn G. (Painted Post NY) Rogers Charles H. (Duxbury MA), Method of measuring degree of partitioning.
  405. Merchav, Shoshana; Meretski, Shai; Zipori, Dov; Kadouri, Avinoam, Method of preparing a conditioned medium from a confluent stromal cell culture.
  406. Mevorach, Dror, Method of preparing apoptotic monocytes.
  407. Madrid, Susan; Lin, Cherry; Zargahi, Masoud Rajabi; Lorentsen, Rikke Høegh; Isaksen, Mai Faurschou; Ward, Michael, Method of producing a lipolytic enzyme.
  408. Shu,Wei; Marton,Ira; Siegel,Daniel L.; Ben Ami,Bravdo; Dekel,Mara; Shoseyov,Oded, Method of producing recombinantβ-glucosidase and an aroma spreading plant.
  409. Darnell, Robert; Jensen, Kirk; Ule, Jernej, Method of purifying RNA binding protein-RNA complexes.
  410. Gazit, Ehud, Method of screening for compounds that disaggregate amyloid aggregates.
  411. De Kreij, Arno; Madrid, Susan Mampusti; Mikkelsen, Jørn Dalgaard; Søe, Jørn Borch, Method of using lipid acyltransferase.
  412. Kreij, Arno De; Madrid, Susan Mampusti; Mikkelsen, Jørn Dalgaard; Søe, Jørn Borch, Method of using lipid acyltransferase.
  413. John W. Hadden, Method to diagnose and monitor cellular immune deficiencies.
  414. Quake, Stephen; Volkmuth, Wayne; Unger, Marc, Methods and apparatus for analyzing polynucleotide sequences.
  415. Quake,Stephen; Braslavsky,Ido; Hebert,Benedict; Kartalov,Emil, Methods and apparatus for analyzing polynucleotide sequences by asynchronous base extension.
  416. Quake,Stephen R., Methods and apparatuses for analyzing polynucleotide sequences.
  417. Afonina, Irina A.; Belousov, Yevgeniy S., Methods and compositions for detecting antibiotic resistant bacteria.
  418. Kurn, Nurith, Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof.
  419. Kurn, Nurith, Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof.
  420. Kurn, Nurith, Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof.
  421. Davis, Noa; Elkeles, Adi; Terkieltaub, Dov; Chausovsky, Alexander, Methods and compositions for identifying a cell phenotype.
  422. Buzby,Philip Richard, Methods and compositions for improving fidelity in a nucleic acid synthesis reaction.
  423. Neufeld, Gera; Akiri, Gal; Vadasz, Zahava; Gengrinovitch, Stela, Methods and compositions for modulating angiogenesis.
  424. Patten Phillip A. ; Stemmer Willem P. C., Methods and compositions for polypeptide engineering.
  425. Patten Phillip A. ; Stemmer Willem P.C., Methods and compositions for polypeptide engineering.
  426. Patten, Phillip A.; Stemmer, Willem P. C., Methods and compositions for polypeptide engineering.
  427. Patten, Phillip A.; Stemmer, Willem P. C., Methods and compositions for polypeptide engineering.
  428. Patten, Phillip A.; Stemmer, Willem P. C., Methods and compositions for polypeptide engineering.
  429. Patten, Phillip A.; Stemmer, Willem P. C., Methods and compositions for polypeptide engineering.
  430. Phillip A. Patten ; Willem P. C. Stemmer, Methods and compositions for polypeptide engineering.
  431. Phillip A. Patten ; Willem P. C. Stemmer, Methods and compositions for polypeptide engineering.
  432. Phillip A. Patten ; Willem P. C. Stemmer, Methods and compositions for polypeptide engineering.
  433. Phillip A. Patten ; Willem P. C. Stemmer, Methods and compositions for polypeptides engineering.
  434. Van Antwerp, William P., Methods and compositions for the inhibition of biofilms on medical devices.
  435. Kurn, Nurith, Methods and compositions for transcription-based nucleic acid amplification.
  436. Smith, Victoria; Ogg, Scott; Van Vlasselaer, Peter; Barry, Vivian E.; Marshall, Derek; Holzer, Alison Kay; Rodriguez, Hector; Oyasu, Miho; McCauley, Scott Alan; Garcia, Carlos Aurelio; Biermann, Donna Hiroko Tokuoka, Methods and compositions for treatment and diagnosis of fibrosis, tumor invasion, angiogenesis, and metastasis.
  437. Smith, Victoria; Ogg, Scott; Van Vlasselaer, Peter; Barry, Vivian E.; Marshall, Derek; Holzer, Alison Kay; Rodriguez, Hector; Oyasu, Miho; McCauley, Scott Alan; Garcia, Carlos Aurelio; Biermann, Donna Hiroko Tokuoka, Methods and compositions for treatment and diagnosis of fibrosis, tumor invasion, angiogenesis, and metastasis.
  438. Ader, Daniel; Dimmic, Matt W.; Li, Zhaolong; Sammons, Robert Douglas; Shah, Ronak Hasmukh; Tao, Nengbing; Wang, Dafu, Methods and compositions for weed control.
  439. Ader, Daniel; Fiinnessy, John J; Li, Zhaolong; Masucci, James D; Shah, Ronak Hasmukh; Tao, Nengbing; Taylor, Jennifer Chou, Methods and compositions for weed control.
  440. Ader, Daniel; Finnessy, John J; Li, Zhaolong; Kapoor, Mahak; Shah, Ronak Hasmukh; Tao, Nengbing; Wang, Dafu, Methods and compositions for weed control.
  441. Levy, Efrat, Methods and compositions relating to cystatin C.
  442. Huberman, Eliezer, Methods and compositions that control lipid production.
  443. Battrell, C Frederick; Gerdes, John; Mordue, Stephen; Capodanno, Jason; Hoekstra, Denise Maxine; Williford, John R; Clemmens, John, Methods and devices for microfluidic point-of-care immunoassays.
  444. Harris, Timothy; Buzby, Philip Richard; Jarosz, Mirna; DiMeo, James Joseph; Gill, Jaime, Methods and devices for nucleic acid sequence determination.
  445. Ovsyshcher, Eli; Fleidervish, Ilya A.; Goldberg, Yuri; Zeldets, Vladimir; Gelvan, Dan, Methods and implantable devices for treating supraventricular arrhythmias.
  446. Quake, Stephen, Methods and kits for analyzing polynucleotide sequences.
  447. Abbaszadegan Morteza ; Di Giovanni George Dominic ; LeChevallier Mark William, Methods and kits for detection of Cryptosporidium parvum using immunomagnetic separation and amplification.
  448. Morteza Abbaszadegan ; George Dominic Di Giovanni ; Mark William LeChevallier, Methods and kits for detection of cryptosporidium parvum.
  449. Idelevich, Pavel; Elkeles, Adi; Terkieltaub, Dov; Eyal, Ami; Gelvan, Dan Jacob, Methods and kits for differential staining of abnormal urinary system cells.
  450. Kurn, Nurith, Methods and probes for detection and/or quantification of nucleic acid sequences.
  451. Chan, Eugene Y., Methods and products for analyzing polymers.
  452. Hanna, Michelle M.; McCarthy, David, Methods and reagents for detecting CpG methylation with a methyl CpG binding protein (MBP).
  453. Yoshimura, Toru; Chiba, Ryotaro, Methods and reagents for diagnosing rheumatoid arthrtis.
  454. Dube, Simant; Sun, Gang; Zhao, Lian-She, Methods and systems for determining a baseline during image processing.
  455. Altschuler, Yoram; Tarcic, Gabi, Methods and systems for identifying patient specific driver mutations.
  456. Dube, Simant; Sun, Gang; Zhao, Lian-She, Methods and systems for image processing of microfluidic devices.
  457. Dube, Simant; Sun, Gang; Zhao, Lian-She, Methods and systems for image processing of microfluidic devices.
  458. Dube, Simant; Sun, Gang; Zhao, Lian-She, Methods and systems for image processing of microfluidic devices.
  459. Chaparian, Michael G.; Azad, Abul, Methods and targets of antibiotic resistance.
  460. Lotan, Tamar; Eckhouse, Shimon, Methods compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue.
  461. Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Methods for detecting nucleic acids encoding human telomerase reverse transcriptase.
  462. Hanna,Michelle M., Methods for determining nucleic acid methylation.
  463. Nath, Avindra; Anderson, Caroline F; Irani, David; Cotter, Robert J; Steiner, Joseph P; Haughey, Norman, Methods for diagnosis and optimizing treatment of multiple sclerosis.
  464. Scholl, David R.; Brown, James L.; Jollick, Jr., Joseph A.; Lollar, Ronald, Methods for direct fluorescent antibody virus detection in liquids.
  465. Cheever Martin A. ; Disis Mary L., Methods for eliciting or enhancing reactivity to HER-2/neu protein.
  466. Braun, Andreas; Koster, Hubert; Van den Boom, Dirk; Yip, Ping; Rodi, Charles; He, Liyan; Chiu, Norman; Jurinke, Christiane, Methods for generating databases and databases for identifying polymorphic genetic markers.
  467. Braun, Andreas; Köster, Hubert; Van Den Boom, Dirk Johannes; Yip, Ping; Rodi, Charles; He, Liyan; Chiu, Norman; Jurinke, Christian, Methods for generating databases and databases for identifying polymorphic genetic markers.
  468. Köster, Hubert; Braun, Andreas; Van Den Boom, Dirk; Ping, Yip; Rodi, Charlie; He, Liyan; Chiu, Norman; Jurinke, Christian, Methods for generating databases and databases for identifying polymorphic genetic markers.
  469. Green, Jr., Richard E.; Lareau, Liana F., Methods for genome assembly and haplotype phasing.
  470. Green, Jr., Richard E.; Lareau, Liana F., Methods for genome assembly and haplotype phasing.
  471. Green, Jr., Richard E.; Lareau, Liana F., Methods for genome assembly and haplotype phasing.
  472. Scholl, David R.; Brown, James L.; Jollick, Jr., Joseph A.; Lollar, Ronald, Methods for liquid direct fluorescent antibody intracellular virus detection.
  473. Allman, Richard; Mantzaris, Debbie; Vom, Eduardo; Lewis, Craig Matthew, Methods for obtaining fetal genetic material.
  474. Bouzek, Heather K., Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions.
  475. Adli, Mazhar; Bernstein, Bradley E.; Mikkelsen, Tarjei S., Methods for preparing sequencing libraries.
  476. Henderson Daniel R. (Benicia CA), Methods for protein binding enzyme complementation assays.
  477. Staples Mark A. ; Haley Carolyn J. ; Parrish Richard F. ; Zmolek Wesley W., Methods for releasing a ligand from a complex.
  478. Jen, Jin; Beaudry, Gary A.; Madden, Stephen L.; Bertlesen, Arthur H.; Sidransky, David, Methods for the diagnosis and treatment of lung cancer.
  479. Jen, Jin; Beaudry, Gary A.; Madden, Stephen L.; Bertlesen, Arthur H.; Sidransky, David, Methods for the diagnosis and treatment of lung cancer.
  480. Kurn, Nurith, Methods of RNA amplification in the presence of DNA.
  481. Roiz, Levava; Schwartz, Betty; Smirnoff, Patricia; Shoseyov, Oded, Methods of and compositions for inhibiting the proliferation of mammalian cells.
  482. Roiz, Levava; Schwartz, Betty; Smirnoff, Patricia; Shoseyov, Oded, Methods of and compositions for inhibiting the proliferation of mammalian cells.
  483. Roiz, Levava; Schwartz, Betty; Smirnoff, Patricia; Shoseyov, Oded, Methods of and compositions for inhibiting the proliferation of mammalian cells.
  484. Roiz, Levava; Schwartz, Betty; Smirnoff, Patricia; Shoseyov, Oded, Methods of and compositions for inhibiting the proliferation of mammalian cells.
  485. Roiz,Levav; Schwartz,Betty; Smirnoff,Patricia; Shoseyov,Oded, Methods of and compositions for inhibiting the proliferation of mammalian cells.
  486. Peled, Tony; Fibach, Eitan; Treves, Avi, Methods of controlling proliferation and differentiation of stem and progenitor cells.
  487. Peled, Tony; Fibach, Eitan; Treves, Avi, Methods of controlling proliferation and differentiation of stem and progenitor cells.
  488. Peled, Tony; Steinhardt, Yair, Methods of culturing and expanding mesenchymal stem cells.
  489. Feinstein,Elena; Mor,Orna, Methods of diagnosing bladder cancer.
  490. Coleman, Roger T.; Bandman, Olga; Wilde, Craig G., Methods of diagnosing pancreatic inflammation by using chemokine PANEC-1 antibodies.
  491. Lockhart, David J.; Chee, Mark S.; Digglemann, Martin; Vetter, Dirk, Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA.
  492. Peled, Tony; Treves, Avi; Rosen, Oren, Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby.
  493. Mitrani, Eduardo N., Methods of generating tissue using devitalized, acellular scaffold matrices derived from micro-organs.
  494. Dekker, Job; Lieberman, Erez; Van Berkum, Nynke; Gnirke, Andreas; Lander, Eric; Nusbaum, Chad; Williams, Louise; Melnikov, Alexandre; Giannoukos, Georgia, Methods of identifying interactions between genomic loci.
  495. Peled, Tony, Methods of improving stem cell homing and engraftment.
  496. Ronen, Gil; Golan, Ezekiel; Karchi, Hagai; Meissner, Rafael, Methods of increasing abiotic stress tolerance and/or biomass in plants.
  497. Ronen, Gil; Golan, Ezekiel; Karchi, Hagai; Meissner, Rafael, Methods of increasing abiotic stress tolerance and/or biomass in plants.
  498. Karchi, Hagai; Ronen, Gil; Yelin, Rodrigo; Rabinovich, Larisa, Methods of increasing abiotic stress tolerance and/or biomass in plants and plants generated thereby.
  499. Ronen, Gil; Golan, Ezekiel; Karchi, Hagai; Meissner, Rafael, Methods of increasing abiotic stress tolerance and/or biomass in plants generated thereby.
  500. Ronen, Gil; Golan, Ezekiel; Karchi, Hagai; Meissner, Rafael, Methods of increasing abiotic stress tolerance, yield and/or biomass in plants.
  501. Guegler, Karl J.; Hawkins, Phillip R.; Wilde, Craig G.; Seilhamer, Jeffrey J., Methods of screening for compounds that modulate the activity of ADEC, a chemokine expressed in inflamed adenoid.
  502. Ashley, Euan A.; Perez, Marco V., Methods of treating heart failure with agonists of hypocretin receptor 2.
  503. Coleman, Roger T.; Bandman, Olga; Wilde, Craig G., Methods of treating pancreatitis.
  504. Guegler, Karl J.; Hawkins, Phillip R.; Wilde, Craig G.; Seilhamer, Jeffrey J., Methods of treatment with anitbodies to a chemokine expressed in inflamed adenoid.
  505. Weiss, Shimon; Bruchez, Marcel; Alivisatos, Paul, Methods of use of semiconductor nanocrystal probes for treating a material.
  506. Lotan, Tamar; Eckhouse, Shimon, Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent.
  507. Kurn, Nurith, Methods, kits and compositions for single primer linear isothermal amplification of nucleic acid sequences.
  508. Maor, Rudy, MicroRNA compositions and methods for enhancing plant resistance to abiotic stress.
  509. Gunning, Kerry B.; Behlke, Mark Aaron, Microarray system with improved sequence specificity.
  510. Gunning, Kerry B; Behlke, Mark Aaron, Microarray system with improved sequence specificity.
  511. Clemmens, John; Battrell, C. Frederick; Gerdes, John; Hoekstra, Denise Maxine, Microfluidic mixing and analytical apparatus.
  512. Battrell, C. Frederick; Clemmens, John; Sprague, Isaac, Microfluidic reactor system.
  513. Parr, Ryan L.; Thayer, Robert; Dakubo, Gabriel; Creed, Jennifer; Robinson, Kerry; Maggrah, Andrea; Reguly, Brian; Harbottle, Andrew; Birch-Machin, Mark, Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers.
  514. Parr, Ryan; Thayer, Robert; Dakubo, Gabriel; Maki, Jennifer; Robinson, Kerry; Maggrah, Andrea; Reguly, Brian; Harbottle, Andrew; Birch-Machin, Mark, Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers.
  515. Gegg, Colin V.; Walker, Kenneth W.; Miranda, Leslie P.; Xiong, Fei, Modified Fc molecules.
  516. Gegg, Colin V.; Walker, Kenneth W.; Miranda, Leslie P.; Xiong, Fei, Modified Fc molecules.
  517. Gegg, Colin V.; Walker, Kenneth W.; Miranda, Leslie P.; Xiong, Fei, Modified Fc molecules.
  518. Gegg, Colin; Xiong, Fei; Sitney, Karen C., Modified Fc molecules.
  519. Gegg, Colin; Xiong, Fei; Sitney, Karen C., Modified Fc molecules.
  520. Gegg, Colin; Xiong, Fei; Sitney, Karen C., Modified Fc molecules.
  521. Gegg, Colin; Xiong, Fei; Sitney, Karen C., Modified Fc molecules.
  522. Gegg, Colin; Xiong, Fei; Sitney, Karen C., Modified Fc molecules.
  523. Gegg, Colin; Xiong, Fei; Sitney, Karen C., Modified Fc molecules.
  524. Gegg,Colin; Xiong,Fei; Sitney,Karen C., Modified Fc molecules.
  525. Park, Dongsu; Spencer, David; Lapteva, Natalia, Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods.
  526. Dempcy, Robert O.; Afonina, Irina A.; Singer, Michael J.; Kutyavin, Igor V., Modified oligonucleotides for mismatch discrimination.
  527. Dempcy,Robert O.; Gall,Alexander A.; Lokhov,Sergey G.; Afonina,Irina A.; Singer,Michael J.; Kutyavin,Igor V.; Vermeulen,Nicolaas M. J., Modified oligonucleotides for mismatch discrimination.
  528. Paris, Daniel; Town, Terrence C.; Mullan, Michael J., Modulation of the phospholipase A2 pathway as a therapeutic.
  529. Hanna, Michelle M.; McCarthy, David, Molecular beacon-based methods for detection of targets using abscription.
  530. Bajic, Vladimir; Kaur, Mandeep, Molecular biomarker set for early detection of ovarian cancer.
  531. Bajic, Vladimir; Kaur, Mandeep, Molecular biomarker set for early detection of ovarian cancer.
  532. Hanna, Michelle M, Molecular detection systems utilizing reiterative oligonucleotide synthesis.
  533. Hanna,Michelle M, Molecular detection systems utilizing reiterative oligonucleotide synthesis.
  534. Hanna,Michelle M, Molecular detection systems utilizing reiterative oligonucleotide synthesis.
  535. Hanna,Michelle M., Molecular detection systems utilizing reiterative oligonucleotide synthesis.
  536. Boge, Annegret; Lavis, Luke D.; Sportsman, J. Richard; Hoekstra, Merl F.; Huang, Wei, Molecular modification assays.
  537. Boge, Annegret; Sportsman, J. Richard; Gaudet, Elizabeth; Yi, George G., Molecular modification assays.
  538. Huang,Wei; Hoekstra,Merl F.; Sportsman,J. Richard; Terpetschnig,Ewald A., Molecular modification assays.
  539. Stein, Emily A.; Evans, Michael A., Molecular nets comprising capture agents and linking agents.
  540. Morr챕,D. James; McCarty,NaMi; Morr챕,Dorothy; Chueh,Pin Ju, Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase.
  541. Chang Chung Nan ; Landolfi Nicholas F. ; Martin Ulrich,DEX, Monoclonal antibodies specific for the platelet derived growth factor .beta. receptor and methods of use thereof.
  542. Youn,Byung Soo; Yang,Young Soo; Lee,Nam Seok; Yu,Kang Yeol; Noh,Young Soon; Park,Hong Je; Youn,Moon Yeon; Chung,Min Sup; Min,Sung Shik; Jeong,Jae Jun, Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody.
  543. Boes, Alexander; Spiegel, Holger; Edgue, Gueven; Beiss, Veronique; Sack, Markus; Reimann, Andreas; Fischer, Rainer, Multi-component-multistage malaria vaccines.
  544. Lee,Jin Po, Multiple analyte assay device.
  545. Ismagilov, Rustem F.; Shen, Feng; Kreutz, Jason E.; Du, Wenbin; Sun, Bing, Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes.
  546. Ismagilov, Rustem F.; Shen, Feng; Kreutz, Jason E.; Du, Wenbin; Sun, Bing, Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes.
  547. Ismagilov, Rustem F.; Shen, Feng; Kreutz, Jason E.; Du, Wenbin; Sun, Bing, Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes.
  548. Chatterjee Malaya ; Kohler Heinz ; Chatterjee Sunil K. ; Foon Kenneth A., Murine anti-idiotype antibody 3H1.
  549. Chatterjee, Malaya; Foon, Kenneth A.; Chatterjee, Sunil K., Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof.
  550. Chatterjee,Malaya; Foon,Kenneth A.; Chatterjee,Sunil K., Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof.
  551. Chatterjee,Malaya; Kohler,Heinz; Chatterjee,Sunil K.; Foon,Kenneth A., Murine monoclonal anti-idiotype antibody 3H1 sequences for human carcinoembryonic antigen.
  552. Miasnikov, Andrei; Kumar, Vijay; Kensch, Oliver; Pellangahr, Klaus; Leuthner, Birgitta; Kettling, Ulrich; Koltermann, Andre, Mutant Citrobacter freundii phytase polypeptide.
  553. Miasnikov, Andrei; Kumar, Vijay; Kensch, Oliver; Pellangahr, Klaus; Leuthner, Birgitta; Kettling, Ulrich; Koltermann, Andre, Mutant citrobacter freundii phytase polypeptide.
  554. Shiloh Yosef,ILX, Mutated forms of the ataxia-telangiectasia gene and method to screen for a partial A-T phenotype.
  555. Shiloh Yosef,ILX ; Tagle Danilo A. ; Collins Francis S., Mutated proteins associated with ataxia-telangiectasia.
  556. Cech, Thomas R.; Lingner, Joachim; Nakamura, Toru; Chapman, Karen B.; Morin, Gregg B.; Harley, Calvin B.; Andrews, William H., Muteins of human telomerase reverse transcriptase lacking telomerase catalytic activity.
  557. Gingeras,Thomas R.; Drenkow,Jorg, Mycobacterial rpoB sequences.
  558. Charvat, Trevor T.; Hu, Cheng; Melikian, Anita; Novack, Aaron; Pennell, Andrew M. K.; Sullivan, Edward J.; Thomas, William D.; Ungashe, Solomon; Zhang, Penglie; Powers, Jay; Punna, Sreenivas, N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides.
  559. Charvat, Trevor T.; Hu, Cheng; Melikian, Anita; Novack, Aaron; Pennell, Andrew M. K.; Sullivan, Edward J.; Thomas, William D.; Ungashe, Solomon; Zhang, Penglie; Powers, Jay; Punna, Sreenivas, N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl)hetaryl arylsulfonamides.
  560. Charvat, Trevor T.; Hu, Cheng; Melikian, Anita; Novack, Aaron; Pennell, Andrew M. K.; Sullivan, Edward J.; Thomas, William D.; Ungashe, Solomon; Zhang, Penglie; Powers, Jay; Punna, Sreenivas, N-(2-(hetaryl)aryl)arylsulfonamides and N-(2-(hetaryl)hetaryl)arylsulfonamides.
  561. Charvat, Trevor T.; Hu, Cheng; Melikian, Anita; Novack, Aaron; Pennell, Andrew M. K.; Sullivan, Edward J.; Thomas, William D.; Ungashe, Solomon; Zhang, Penglie; Powers, Jay; Punna, Sreenivas, N-(2-(hetaryl)aryl)arylsulfonamides and n-(2-(hetaryl)hetaryl) arylsulfonamides.
  562. Jarvis, Gary A.; John, Constance M.; Leffler, Hakon, N-terminally truncated galectin-3 for use in treating cancer.
  563. Golomb, Gershon; Sacks, Haigt; Najareh, Yousef; Fishbein, Elia; Chorny, Michael, Nanoparticles containing polymeric nucleic acid homologs.
  564. Tainsky, Michael A.; Draghici, Sorin; Lin, Ho-Sheng, Neoepitope detection of disease using protein arrays.
  565. Joseph Rajiv ; Dou Dexian, Neuronal-neonatal gene: neuronatin.
  566. Lee, Daniel H. S.; Pepinsky, R. Blake; Li, Weiwei; Relton, Jane K.; Worley, Dane S.; Strittmatter, Stephen M.; Sah, Dinah W. Y.; Rabacchi, Sylvia A., Nogo receptor antagonists.
  567. Lee, Daniel H. S.; Wen, Dingyi; Pepinsky, R. Blake; Relton, Jane K.; Wang, Xinzhong; Lugovskoy, Alexey; Meier, Werner; Garber, Ellen A.; Silvian, Laura; Weinreb, Paul H., Nogo receptor antagonists.
  568. Lee,Daniel H. S.; Pepinsky,R. Blake; Li,Weiwei; Relton,Jane K.; Worley,Dane S.; Strittmatter,Stephen M.; Sah,Dinah W. Y.; Rabacchi,Sylvia A., Nogo receptor antagonists.
  569. Lee, Daniel H. S.; Wen, Dingyi; Pepinsky, R. Blake; Relton, Jane K.; Wang, Xinzhong; Lugovskoy, Alexey; Meier, Werner; Garber, Ellen A.; Silvian, Laura; Weinreb, Paul H., Nogo receptor antagonists and methods of increasing neurite outgrowth.
  570. Rouhani Riaz ; Sigler Gerald F., Non-hydrolyzable analogs of heroin metabolites suitable for use in immunoassay.
  571. Akhavan-Tafti, Hashem, Nonseparation assay methods.
  572. Akhavan-Tafti, Hashem, Nonseparation assay methods.
  573. Akhavan-Tafti, Hashem, Nonseparation assay methods.
  574. Gohlke, James R.; Hedaya, Eddie; Kang, Jemo; Mier, Jeanette D., Novel chromogenic and/or fluorogenic substrates for monitoring catalytic or enzymatic activity.
  575. Hochberg, Avraham; Matouk, Imad, Nucleic acid agents for downregulating H19 and methods of using same.
  576. Hochberg, Avraham; Matouk, Imad, Nucleic acid agents for downregulating H19, and methods of using same.
  577. Nazarenko Irina A. ; Bhatnagar Satish K. ; Winn-Deen Emily S. ; Hohman Robert J., Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon.
  578. Nazarenko Irina A. ; Bhatnagar Satish K. ; Winn-Deen Emily S. ; Hohman Robert J., Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon.
  579. Nazarenko Irina A. ; Bhatnagar Satish K. ; Winn-Deen Emily S. ; Hohman Robert J., Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon.
  580. Kurn, Nurith; Wang, Shenglong, Nucleic acid amplification procedure using RNA and DNA composite primers.
  581. Cech, Thomas R.; Lingner, Joachim; Nakamura, Toru; Chapman, Karen B.; Morin, Gregg B.; Harley, Calvin B.; Andrews, William H., Nucleic acid compositions for eliciting an immune response against telomerase reverse transcriptase.
  582. Hochberg, Avraham, Nucleic acid constructs, pharmaceutical compositions and methods of using same for treating cancer.
  583. McGall, Glenn Hugh; Barone, Anthony D., Nucleic acid labeling compounds.
  584. McGall, Glenn Hugh; Barone, Anthony Dale, Nucleic acid labeling compounds.
  585. McGall, Glenn; Barone, Anthony D., Nucleic acid labeling compounds.
  586. McGall, Glenn; Barone, Anthony D., Nucleic acid labeling compounds.
  587. McGall,Glenn H.; Barone,Anthony D., Nucleic acid labeling compounds.
  588. McGall,Glenn H.; Barone,Anthony D., Nucleic acid labeling compounds.
  589. McGall,Glenn H.; Barone,Anthony D.; Li,Handong, Nucleic acid labeling compounds.
  590. McGall,Glenn; Barone,Anthony D., Nucleic acid labeling compounds.
  591. McGall,Glenn; Barone,Anthony D., Nucleic acid labeling compounds.
  592. McGall, Glenn H.; Barone, Anthony D., Nucleic acid labelling compounds.
  593. Putnam, Nicholas H.; Stites, Jonathan C.; Rice, Brandon J., Nucleic acid sequence assembly.
  594. Ronald D. Vale ; James J. Hartman, Nucleic acids encoding a katanin p60 subunit.
  595. Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Nucleic acids encoding human telomerase reverse transcriptase and related homologs.
  596. Morin, Gregg B., Nucleic acids encoding inactive variants of human telomerase.
  597. Liu,David R., Nucleotide analogs.
  598. Ronen, Gil; Rabinovich, Larisa; Meissner, Rafael; Karchi, Hagai, Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same.
  599. Ronen,Gil; Rabinovich,Larisa; Meissner,Rafael; Karchi,Hagai, Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same.
  600. Markle, David R.; Suri, Jeff T.; Wessling, Ritchie A.; Romey, Matthew A., Optical determination of pH and glucose.
  601. Markle, David R; Suri, Jeff T; Wessling, Ritchie A; Romey, Matthew A, Optical determination of pH and glucose.
  602. Jorma Virtanen, Optical disk-based assay devices and methods.
  603. Markle, David R.; Gamsey, Soya; Peyser, Thomas A., Optical sensor configuration for ratiometric correction of blood glucose measurement.
  604. Markle, David R.; Gamsey, Soya; Peyser, Thomas A., Optical sensor configuration for ratiometric correction of glucose measurement.
  605. Petersson,Bo; Kristensen,Jesper, Optical sensor containing particles for in situ measurement of analytes.
  606. Stanley Christopher John,GBX ; Weber Anders,DKX, Optical sensor for in situ measurement of analytes.
  607. Stanley, Christopher John; Weber, Anders, Optical sensor for in situ measurement of analytes.
  608. Weber, Anders; Stanley, Christopher J., Optical sensor for in situ measurement of analytes.
  609. Markle, David R.; Wessling, Ritchie A.; Kolehmainen, Donald J., Optical systems and methods for ratiometric measurement of blood glucose concentration.
  610. Markle, David R.; Wessling, Ritchie A.; Kolehmainen, Donald J., Optical systems and methods for ratiometric measurement of blood glucose concentration.
  611. Briand, Jean Paul; Guichard, Gilles; Courty, Jose; Zimmer, Robert H.; Devin, Chantal; Lang, Annie; Zhang, Haixang; Hovanessian, Ara, Optically pure compounds for improved therapeutic efficiency.
  612. Shimon Weiss ; Marcel Bruchez, Jr. ; Paul Alivisatos, Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  613. Weiss, Shimon; Bruchez, Jr., Marcel; Alivisatos, Paul, Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  614. Weiss, Shimon; Bruchez, Jr., Marcel; Alivisatos, Paul, Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  615. Weiss,Shimon; Bruchez, Jr.,Marcel; Alivisatos,Paul, Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  616. Weiss,Shimon; Bruchez, Jr.,Marcel; Alivisatos,Paul, Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  617. Lieberman, Erez; Gnirke, Andreas; Aird, Daniel, Parallel proximity ligation event analysis.
  618. Fima, Udi Eyal; Hershkovitz, Oren, Pegylated OXM variants.
  619. Fima, Udi Eyal; Hershkovitz, Oren, Pegylated OXM variants.
  620. Richard Y. Liu ; Kenneth S. Zuckerman, Peptide antagonists of tumor necrosis factor alpha.
  621. Reches, Meital; Gazit, Ehud, Peptide nanostructures and methods of generating and using the same.
  622. Gazit, Ehud; Reches, Meital, Peptide nanostructures encapsulating a foreign material and method of manufacturing same.
  623. Gazit, Ehud, Peptides and methods using same for diagnosis and treatment of amyloid-associated disease.
  624. Gazit, Ehud, Peptides and methods using same for diagnosis and treatment of amyloid-associated disease.
  625. Gazit, Ehud, Peptides directed for diagnosis and treatment of amyloid-associated disease.
  626. Gazit, Ehud, Peptides directed for diagnosis and treatment of amyloid-associated diseases.
  627. Neufeld, Gera; Akiri, Gal; Vadasz, Zahava; Gengrinovitch, Stela, Pharmaceutical compositions and methods useful for modulating angiogenesis, inhibiting metastasis and tumor fibrosis, and assessing the malignancy of colon cancer tumors.
  628. Pease John S. ; Kirakossian Hrair ; Wagner Daniel B. ; Ullman Edwin F., Photoactivatable chemiluminescent matrices.
  629. Stein,Hanan; Zilberstein,Aviah; Miller,Gadi; Kapulnik,Yoram, Plants tolerant of environmental stress conditions, methods of generating same and novel polynucleotide sequence utilized thereby.
  630. Braun, Andreas, Polymorphic kinase anchor proteins and nucleic acids encoding the same.
  631. Harats, Dror; Greenberger, Shoshana; Breitbart, Eyal, Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy.
  632. Sammons, Robert D; Ivashuta, Sergey; Liu, Hong; Wang, Dafu; Feng, Paul C. C.; Kouranov, Andrei Y; Andersen, Scott E, Polynucleotide molecules for gene regulation in plants.
  633. Ayal, Sharon; Karchi, Hagai; Gold, Evgenia; Bekerman, Laura, Polynucleotides and polypeptides involved in plant fiber development and methods of using same.
  634. Ayal, Sharon; Karchi, Hagai; Gold, Evgenia; Bekerman, Laura, Polynucleotides and polypeptides involved in plant fiber development and methods of using same.
  635. Ronen, Gil; Gold, Evgenia; Yelin, Rodrigo; Meissner, Rafael; Karchi, Hagai; Ayal, Sharon, Polynucleotides and polypeptides involved in plant fiber development and methods of using same.
  636. Chatterjee,Malaya; Foon,Kenneth A.; Chatterjee,Sunil K., Polynucleotides related to murine anti-idiotype antibody 11D10 and methods of use thereof.
  637. Emmanuel, Eyal; Ronen, Gil; Savir, Noa, Polynucleotides, polypeptides and methods for increasing oil content, growth rate and biomass of plants.
  638. Emmanuel, Eyal; Ronen, Gil; Savir, Noa, Polynucleotides, polypeptides and methods for increasing oil content, growth rate and biomass of plants.
  639. Ronen, Gil; Karchi, Hagai; Diber, Alex; Vinocur, Basia Judith; Ayal, Sharon; Emmanuel, Eyal; Gang, Michael; Dimet, Dotan, Polynucleotides, polypeptides encoded thereby, and methods of using same for increasing abiotic stress tolerance and/or biomass and/or yield in plants expressing same.
  640. Ronen, Gil; Karchi, Hagai; Diber, Alex; Vinocur, Basia Judith; Ayal, Sharon; Emmanuel, Eyal; Gang, Michael; Dimet, Dotan, Polynucleotides, polypeptides encoded thereby, and methods of using same for increasing abiotic stress tolerance and/or biomass and/or yield in plants expressing same.
  641. Kelly, Denise; Patterson, Angela; Monnais, Edouard; Mulder, Imke, Polypeptide and immune modulation.
  642. Ronald D. Vale ; James J. Hartman, Polypeptides for the detection of microtubule depolymerization inhibitors.
  643. Rajendra Singh ; Harshvardhan Mehta, Polysaccharide conjugates of biomolecules.
  644. Singh Rajendra ; Mehta Harshvardhan, Polysaccharide conjugates of biomolecules.
  645. Singh, Rajendra; Mehta, Harshvardhan, Polysaccharide conjugates of biomolecules.
  646. Belmont, Brian J.; Goldfless, Stephen J.; Marletta, Michael A.; Niles, Jacquin C., Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers.
  647. Mukherjee, Rupak; Gold, Michael R.; Spinale, Francis G., Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling.
  648. Spinale, Francis G.; Stroud, Robert E.; Zile, Michael R., Predicting heart failure following myocardial infarction by protease and protease inhibitor profiling.
  649. Colgin, Mark; Newman, Diane; Landmann, Cathy; Roth, Jay W.; Hurst, Roger; Hansen, Thomas R.; Austin, Kathleen Jeanette, Pregnancy detection.
  650. Chang, Christopher J., Pro-fluorescent probes.
  651. Diaz Torres,Maria R., Production of secreted polypeptides.
  652. Diaz-Torres, Maria R., Production of secreted polypeptides.
  653. Diaz-Torres, Maria R., Production of secreted polypeptides.
  654. Donaldson,Iain Alasdair; Rasmussen,Thomas Bruun, Promoter.
  655. Morin, Gregg B.; Andrews, William H., Promoter for telomerase reverse transcriptase.
  656. Buckler Robert T. (Edwardsburg MI) Carrico Robert J. (Elkhart IN), Propranolol immunogen and antibodies.
  657. An, Gang; Veltri, Robert, Prostate-specific gene for diagnosis, prognosis and management of prostate cancer.
  658. Estell,David A., Proteases from GRAM positive organisms.
  659. Estell, David A., Proteases from gram positive organisms.
  660. Estell, David A., Proteases from gram positive organisms.
  661. Estell, David A., Proteases from gram positive organisms.
  662. Estell,David A., Proteases from gram positive organisms.
  663. Estell,David A., Proteases from gram positive organisms.
  664. Estell,David A., Proteases from gram positive organisms.
  665. Estell,David A., Proteases from gram positive organisms.
  666. Estell,David A., Proteases from gram positive organisms.
  667. Estell,David A., Proteases from gram positive organisms.
  668. Estell, David A., Proteases from gram-positive organisms.
  669. Estell, David A., Proteases from gram-positive organisms.
  670. Estell, David A., Proteases from gram-positive organisms.
  671. Estell, David A., Proteases from gram-positive organisms.
  672. Estell, David A., Proteases from gram-positive organisms.
  673. Estell, David A., Proteases from gram-positive organisms.
  674. Estell, David A., Proteases from gram-positive organisms.
  675. Estell, David A., Proteases from gram-positive organisms.
  676. Estell, David A., Proteases from gram-positive organisms.
  677. Estell,David A., Proteases from gram-positive organisms.
  678. Estell,David A., Proteases from gram-positive organisms.
  679. Estell,David A., Proteases from gram-positive organisms.
  680. Estell,David A., Proteases from gram-positive organisms.
  681. Rousso, Benny; Sabbah, Hani N., Protein activity modification.
  682. Derkx, Patrick Maria Franciscus; Mulder, Harm; Nikolaev, Igor, Proteins.
  683. Haugland, Richard; Leung, Wai-Yee; Liu, Jixiang, Pyrenyloxysulfonic acid fluorescent agents.
  684. Haugland, Richard; Leung, Wai-Yee; Liu, Jixiang, Pyrenyloxysulfonic acid fluorescent agents.
  685. Haugland, Richard; Leung, Wai-Yee; Liu, Jixiang, Pyrenyloxysulfonic acid fluorescent agents.
  686. Liu, Jixiang; Haugland, Richard; Leung, Wai-Yee, Pyrenyloxysulfonic acid fluorescent agents.
  687. Pirio Marcel Rene ; Davalian Dariush ; Ishkanian Jacqueline Sadakan ; Ullman Edwin F., Reagents and methods for specific binding assays.
  688. Staples, Mark A.; Haley, Carolyn J.; Parrish, Richard F.; Zmolek, Wesley W., Reagents for assays for ligands.
  689. Staples Mark A. ; Parrish Richard F., Reagents for assays for mycophenolic acid.
  690. Winger Edward E. ; Kessler Donald J. ; Hargrove David E., Real time homogeneous nucleotide assay.
  691. Remacle, José; Alexandre, Isabelle; Margaine, Sylvain; Husar, Dieter, Real-time quantification of multiple targets on a micro-array.
  692. Fu, Tsu-Ju; Chang, Shang-Chia; Fann, Jenn-Yeh, Real-time sequencing method for single molecule.
  693. Ullman Edwin F. (Atherton CA), Receptor fluorescent immunoassay.
  694. Tindall Donald J. ; Young Charles Y. F. ; Saedi Mohammad Saeed ; Mikolajczyk Stephen D., Recombinant hK2 polypeptide.
  695. Roiz, Levava; Schwartz, Betty; Smirnoff, Patricia; Shoseyov, Oded, Recombinant human T2 RNase and uses thereof.
  696. Morin, Gregg B.; Andrews, William H., Regulatory segments of the human gene for telomerase reverse transcriptase.
  697. Morin,Gregg B.; Andrews,William H., Regulatory segments of the human gene for telomerase reverse transcriptase.
  698. Trieu, Vuong, SPARC binding ScFcs.
  699. Trieu, Vuong, SPARC binding ScFcs.
  700. Trieu, Vuong, SPARC binding ScFvs.
  701. Trieu, Vuong, SPARC binding ScFvs.
  702. Trieu, Vuong, SPARC binding ScFvs.
  703. Trieu, Vuong, SPARC binding peptides and uses thereof.
  704. Trieu, Vuong, SPARC binding peptides and uses thereof.
  705. Battrell, C. Frederick; Sprague, Isaac; Bragd, Matthew Scott; Capodanno, Jason, Sample-to-answer microfluidic cartridge.
  706. Andruzzi, Luisa, Scavenger compounds for improved sequencing-by-synthesis.
  707. Karlish, Steven J. D.; Katz, Adriana; Tal, Daniel M.; Marcovich, Arie, Selective inhibitors of α2 isoform of Na,K-ATPase and use thereof for reduction of intra-ocular pressure and as cardiotonic agents.
  708. Weiss Shimon ; Bruchez Marcel ; Alivisatos Paul, Semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  709. Weiss, Shimon; Bruchez, Marcel; Alivisatos, Paul, Semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  710. Weiss, Shimon; Bruchez, Marcel; Alivisatos, Paul, Semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  711. Weiss, Shimon; Bruchez, Marcel; Alivisatos, Paul, Semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  712. Weiss, Shimon; Bruchez, Marcel; Alivisatos, Paul A., Semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  713. Bawendi, Moungi G.; Jensen, Klavs F., Semiconductor nanocrystals for inventory control.
  714. Markle, David R.; Markle, William H., Sensor for percutaneous intravascular deployment without an indwelling cannula.
  715. Romey, Matthew A.; Gamsey, Soya; Markle, David R., Sensors with thromboresistant coating.
  716. Gargir, Ari; Semenov, Eugene; Reinhartz, Avraham; Alajem, Sara, Sequential lateral flow capillary device for analyte determination.
  717. Estell,David A., Serine proteases from gram-positive microorganisms.
  718. Estell,David A., Serine proteases from gram-positive microorganisms.
  719. Estell,David A., Serine proteases from gram-positive microorganisms.
  720. Estell,David A., Serine proteases from-gram-positive microorganisms.
  721. Lapidus, Stanley N.; Buzby, Philip R.; Harris, Timothy D., Short cycle methods for sequencing polynucleotides.
  722. Lapidus, Stanley; Buzby, Philip Richard; Harris, Timothy, Short cycle methods for sequencing polynucleotides.
  723. Lapidus, Stanley; Buzby, Phillip Richard; Harris, Timothy, Short cycle methods for sequencing polynucleotides.
  724. Lapidus,Stanley N; Buzby,Philip Richard; Harris,Timothy, Short cycle methods for sequencing polynucleotides.
  725. Lapidus,Stanley; Buzby,Phillip Richard; Harris,Timothy, Short cycle methods for sequencing polynucleotides.
  726. Short, Jay Milton, Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts.
  727. Short, Jay Milton, Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts.
  728. Short, Jay Milton, Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts.
  729. Williams,John G. K.; Bashford,Gregory R., Single molecule detection systems and methods.
  730. Lapidus, Stanley, Single molecule sequencing of captured nucleic acids.
  731. Lapidus, Stanley N., Single molecule sequencing of captured nucleic acids.
  732. Ismagilov, Rustem F.; Du, Wenbin; Li, Liang; Shen, Feng; Nichols, Kevin Paul Flood; Chen, Delai; Kreutz, Jason Eugene, Slip chip device and methods.
  733. Virtanen Jorma, Spatially addressable, cleavable reflective signal elements, assay device and method.
  734. Virtanen Jorma, Spatially addressable, cleavable reflective signal elements, assay device and method.
  735. Bardat, Annie; Begin, Edith; Khandoudi, Nassirah; Just, Olivier; Chtourou, Sami; Schmitthaeusler, Roland, Stabilising formulation for immunoglobulin G compositions in liquid form and in lyophilised form.
  736. Buzby,Philip Richard, Stabilizing a nucleic acid for nucleic acid sequencing.
  737. Saedi Mohammad Saeed ; Mikolajczyk Stephen Dennis ; Kumar Abhay ; Kuus-Reichel Kristine, Stable variant hK2 polypeptide.
  738. Kollet, Orit; Lapidot, Tsvee, Stem cells having increased sensitivity to SDF-1 and methods of generating and using same.
  739. Lotan, Tamar; Eckhouse, Shimon; Shaoul, Esther, Stinging cells expressing an exogenous polynucleotide encoding a therapeutic, diagnostic or a cosmetic agent and methods compositions and devices utilizing such stinging cells or capsules derived therefrom for delivering the therapeutic, diagnostic or cosmetic agent into a tissue.
  740. Arad, Shoshana; Plesser, Lena; Weinstein, Yaakov, Sulfotransferase of a red microalga and uses thereof.
  741. Klaubert Dieter H. ; Gee Kyle R., Synthesis of fluorinated xanthene derivatives.
  742. Rajski,Scott R.; Comstock,Lindsay R.; Weller,Rachel L., Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use.
  743. Fasel, Nicolas; Kūndig, Amal, Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of cellular relaxation.
  744. Shinnick Thomas M. (Del Mar CA) Minden Percy (LaJolla CA) Houghten Richard A. (Solana Beach CA), Synthetic polypeptides and receptor molecules derived therefrom and methods of use.
  745. Segev, David, System for delivering therapeutic agents into living cells and cells nuclei.
  746. Segev, David, System for delivering therapeutic agents into living cells and cells nuclei.
  747. Segev, David, System for delivering therapeutic agents into living cells and cells nuclei.
  748. Segev, David, System for delivering therapeutic agents into living cells and cells nuclei.
  749. Segev, David, System for delivering therapeutic agents into living cells and cells nuclei.
  750. Obremski Robert J. ; Silzel John W., System for simultaneously conducting multiple ligand binding assays.
  751. Pascual, Maria Virginia; Banchereau, Jacques F.; Bennett, Lynda B., Systemic lupus erythematosus diagnostic assay.
  752. Dempcy, Robert O.; Gall, Alexander A.; Lokhov, Sergey G.; Afonina, Irina A.; Singer, Michael J.; Singer, legal representative, Karen M.; Kutyavin, Igor V.; Vermeulen, Nicolaas M. J., Systems and methods for predicting oligonucleotide melting temperature (TS).
  753. Weber,Aaron; Tracy,David H., Systems and methods for reducing detected intensity non-uniformity in a laser beam.
  754. Dempcy, Robert O.; Gall, Alexander A.; Lokhov, Sergey G.; Afonina, Irina A.; Kutyavin, Igor V.; Vermeulen, Nicolaas M. J., TM leveling methods.
  755. Bawendi,Moungi G.; Mikulec,Frederic V.; Kim,Sungjee, Tellurium-containing nanocrystalline materials.
  756. Cech Thomas R. ; Lingner Joachim,CHX, Telomerase.
  757. Cech Thomas R. ; Lingner Joachim,CHX ; Nakamura Toru ; Chapman Karen B. ; Morin Gregg B. ; Harley Calvin B. ; Andrews William H., Telomerase.
  758. Cech, Thomas R.; Lingner, Joachim; Nakamura, Toru; Chapman, Karen B.; Morin, Gregg B.; Harley, Calvin B.; Andrews, William H., Telomerase.
  759. Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Telomerase.
  760. Morin,Gregg B.; Lichtsteiner,Serge; Vasserot,Alain; Adams,Robert; Andrews,William H., Telomerase promoters sequences for screening telomerase modulators.
  761. Spiegel, Holger; Boes, Alexander; Edgue, Gueven; Beiss, Veronique; Sack, Markus; Reimann, Andreas; Fischer, Rainer, Three-component-multistage malaria vaccine.
  762. Scanlan,Thomas S.; Hart,Matthew E.; Grandy,David K.; Bunzow,James R.; Miyakawa,Motonori; Tan,Edwin Saavedra; Suchland,Katherine L., Thyronamine derivatives and analogs and methods of use thereof.
  763. Dempcy,Robert O.; Gall,Alexander A; Lokhov,Sergey G.; Afonina,Irina A.; Singer,Michael J.; Kutyavin,Igor V.; Vermeulen,Nicolaas M. J., Tleveling compositions.
  764. Dempcy, Robert O.; Gall, Alexander A.; Lokhov, Sergey G.; Afonina, Irina A.; Singer, Michael J.; Kutyavin, Igor V.; Vermeulen, Nicolaas M. J., Tm leveling methods.
  765. Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Treating cancer using a telomerase vaccine.
  766. Bron,Sierd; Jongbloed,Jan D. H.; Muller,Joerg; Van Dijl,Jan M., Twin-arginine translocation in.
  767. Bron, Sierd; Jongbloed, Jan D. H.; Muller, Joerg; Van Dijl, Jan M., Twin-arginine translocation in .
  768. Bron, Sierd; Jongbloed, Jan D. H.; Muller, Joerg; Van Dijl, Jan M., Twin-arginine translocation in .
  769. Bron, Sierd; Jongbloed, Jan D. H.; Muller, Joerg; Van Dijl, Jan M., Twin-arginine translocation in .
  770. Vinocur, Basia J.; Ayal, Sharon; Diber, Alex; Emmanuel, Eyal; Ronen, Gil; Gang, Michael; Dimet, Dotan; Karchi, Hagai; Herschkovitz, Yoav, Use of CAD genes to increase nitrogen use efficiency and low nitrogen tolerance to a plant.
  771. Markle, William H.; Markle, David R., Use of an equilibrium intravascular sensor to achieve tight glycemic control.
  772. Markle, William H.; Markle, David R., Use of an equilibrium intravascular sensor to achieve tight glycemic control.
  773. Markle, William H.; Markle, David R., Use of an equilibrium sensor to monitor glucose concentration.
  774. Courty, Jose; Hovanessian, Ara; Briand, Jean Paul; Guichard, Gilles; Hamma, Yamina, Use of multivalent synthetic ligands of surface nucleolin for treating cancer or inflammation.
  775. Courty, José; Hovanessian, Ara; Briand, Jean Paul; Guichard, Gilles; Hamma, Yamina, Use of multivalent synthetic ligands of surface nucleolin for treating cancer or inflammation.
  776. Roberts, David D.; Krutzsch, Henry C.; Krutzsch, legal representative, Christine, Use of semenogelin in the diagnosis, prognosis and treatment of cancer.
  777. Lotan, Tamar; Eckhouse, Shimon, Use of stinging cells/capsules for the delivery of active agents to keratinous substances.
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