$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색도움말
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"

통합검색

도움말도움말
상세검색 다국어 입력

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Drug excipient of silicone rubber

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61K-009/00   
미국특허분류(USC) 424/22 ; 128/130 ; 128/260 ; 424/14
출원번호 US-0616001 (1975-09-23)
우선권정보 DT-2445971 (1974-09-24)
발명자 / 주소
  • Schopflin Gisela (Berlin DT)
출원인 / 주소
  • Schering Aktiengesellschaft (Berlin & Bergkamen DT 03)
인용정보 피인용 횟수 : 42  인용 특허 : 0
초록
▼

Nontoxic sustained release pharmaceutical compositions containing one or more nonionic, lipophilic drugs in a cured low temperature vulcanizable (LTV) silicone elastomer excipient are prepared substantially free of toxic vulcanizing agents or drug-reactive by-products in the elastomeric material by curing with a vulcanizable composition comprising A. A POLYDIMETHYLSILOXANE HAVING VINYL GROUPS ON BOTH ENDS; B. A COPOLYMER CONSISTING ESSENTIALLY OF SiO2 units, (CH3)3SiO0.5 units, Vinyl(CH3)2SiO0.5 units; and C. A CROSS-LINKING Si-H component, consisting es...

대표
청구항
▼

A non-toxic sustained release pharmaceutical composition in the form of a shaped object having a Shore A hardness of 45-70, consisting essentially of a safe and pharmaceutically active amount of a nonionic lipophilic drug having a dissociation constant of less than 107 and which is olefinically or acetylenically unsaturated and soluble in ether, chloroform or benzene, said drug being dissolved or uniformly suspended in a non-toxic vulcanized LTV linear dimethylpolysiloxane elastomer and said composition being prepared by reacting, at an elevated temperat...

이 특허를 인용한 특허 (42)

  1. Mustacich Robert V. (Fairfield OH) Lucas Donald S. (Fairfield OH) Stone Roger L. (Fairfield OH), Antimicrobial polymer compositions.
  2. Mustacich Robert V. (Fairfield OH) Lucas Donald S. (Fairfield OH) Stone Roger L. (Fairfield OH), Antimicrobial polymer compositions.
  3. Farley James J. (505 E. Lancaster Ave. ; Apt. 412 St. David PA 19087), Chemical dispensing device and method.
  4. Berg, Eric P.; Stella, Rita, Coating with antimicrobial agents.
  5. Berg, Eric P.; Stella, Rita, Coating with antimicrobial agents.
  6. Devlin, Brid; Holt, Jonathon Daryll; Brimer, Andrew Nathan; Nuttall, Jeremy Peter; Malcolm, Karl; Fetherston, Susan Margaret; Boyd, Peter John James, Combination therapy intravaginal rings.
  7. Burck Philip J. (Indianapolis IN) Zimmerman Ronald E. (Danville IN) Thakkar Arvind L. (Indianapolis IN), Contraceptive methods and compositions.
  8. Zimmerman Ronald E. (Danville IN) Burck Philip J. (Indianapolis IN) Jones C. David (Indianapolis IN) Thakkar Arvind L. (Indianapolis IN), Contraceptive methods and compositions.
  9. Zimmerman Ronald E. (Danville IN) Burck Philip J. (Indianapolis IN) Jones C. David (Indianapolis IN) Thakkar Arvind L. (Indianapolis IN), Contraceptive methods and compositions.
  10. Zimmerman Ronald E. (Danville IN) Burck Philip J. (Indianapolis IN) Jones C. David (Indianapolis IN) Thakkar Arvind L. (Indianapolis IN), Contraceptive methods and compositions.
  11. Schaeffler, Achim, Delayed-release glucocorticoid treatment of rheumatoid disease.
  12. Schaeffler, Achim, Delayed-release glucocorticoid treatment of rheumatoid disease.
  13. Millar Thomas D. (Hamilton NZX), Devices which are adapted to slowly release chemicals, such as hormones, drugs and minerals.
  14. Cyprien Guy (L\Hay les Roses FRX) Fisch Alain (Paris FRX) Haggiage Johnny (Lyon FRX) Porte Hugues (Caluire FRX) Prazuck Thierry (Paris FRX) Torres Ghislaine (Lyon FRX), Diorganopolysiloxane dosage forms for the controlled release of iodine values.
  15. Leeper Harold M. (Mountain View CA), Elastomeric active agent delivery system and method of use.
  16. Allen Dwight L. (Akron OH), Elastomeric composition containing therapeutic agents and articles manufactured therefrom.
  17. Allen Dwight L. (Akron OH), Elastomeric composition containing therapeutic agents and articles manufactured therefrom.
  18. Allen Dwight L. (Akron OH), Elastomeric composition containing therapeutic agents and articles manufactured therefrom.
  19. Kim Benjamin K. (Toms River NJ), Estradiol transdermal delivery system.
  20. Malcolm, Karl; Woolfson, David; Elliott, Grant; Shephard, Martin, Intravaginal drug delivery devices for the administration of an antimicrobial agent.
  21. Muldoon, Brendan; Lorimer, Colin; Gilligan, Claire, Intravaginal matrix drug delivery devices.
  22. Nash Harold A. (Harrington Park NJ) Mishell ; Jr. Daniel R. (Palos Verdes Estates CA), Intravaginal ring.
  23. McIntyre, Jon T.; Daignault, Kenneth, Medical devices for treating urological and uterine conditions.
  24. Robertson Dale N. (Scotch Plains NJ) Braun John (Westbury NY), Method for making an IUD with shrinking of a medicated attachment onto a support.
  25. Igarashi Masao (357-4 ; Hiyoshi-cho H-chome Maebashi-shi ; Gunma JPX), Method for treating endometriosis with topical preparations containing danazol.
  26. Millar Thomas D. (Hamilton NZX) Miller David M. (Hamilton NZX), Methods of making intra-vaginal devices and/or intra-vaginal devices.
  27. Schoenwald Ronald D. (Iowa City IA), Ophthalmic compositions and process for preparing.
  28. Schoenwald Ronald D. (Iowa City IA), Opthalmic composition.
  29. Di Luccio Robert C. (Wilmington DE) Duggins Ray B. (Chadds Ford PA) Shefter Eli (Media PA), Pharmaceutical compositions containing hollow fine tubular drug delivery systems.
  30. Malcolm, Karl; Woolfson, David; Romano, Joseph, Platinum-catalyzed intravaginal rings.
  31. Malcolm, Karl; Woolfson, David; Romano, Joseph, Platinum-catalyzed intravaginal rings.
  32. Cyprien Guy (L\Hay les Roses FRX) Fisch Alain (Paris FRX) Haggiage Johnny (Lyons FRX) Porte Hugues (Caluire FRX) Prazuck Thierry (Paris FRX) Torres Ghislaine (Lyons FRX), Polyaddition silicone elastomer dosage forms for the controlled release of iodine values.
  33. Ascher Frdric M. (Carros FRX) Cuvelier Jacques A. (St. Martin du Var FRX), Programmed release device and method of use thereof.
  34. Hudson James L. (Indianapolis IN) Wagner Jack F. (Greenfield IN), Removable drug implant.
  35. Fujioka Keiji (Amagasaki JPX) Sato Shigeji (Ibaraki JPX) Tamura Nobuhiko (Toyonaka JPX) Takada Yoshihiro (Takatsuki JPX), Sustained release composition for pharmaceutical substances comprising a silicone elastomer carrier.
  36. Korol Bernard (11908 Country Club Dr. St. Louis MO 63131), Synthetic resin wound dressing and method of treatment using same.
  37. Drobish James L. (Cincinnati OH) Gougeon Thomas W. (Cincinnati OH), Vaginal contraceptive.
  38. Drobish James L. (Wyoming OH) Gougeon Thomas W. (Springfield Township ; Hamilton County OH), Vaginal contraceptive.
  39. Drobish James L. (Cincinnati OH), Vaginal contraceptive and method of using.
  40. Schopflin Gisela (Berlin DEX) Laudahn Gerhard (Berlin DEX) Muhe Barbara (Berlin DEX) Hartmann Heidemarie (Berlin DEX) Windt Fred (Berlin DEX), Vaginal ring.
  41. Zimmermann Ingfried (Berlin DEX) Windt Fred (Berlin DEX) Reck Hans-Jrgen (Berlin DEX), Vaginal ring.
  42. Dowrick John S. (Leigh GB2) Balderstone Peter (Worthing GB2), Veterinary compositions for reducing mammary infections.

IPC 상위 출원인