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A closure structure for a vial or container, preferably of the two-compartment type, wherein lyophilized medication is contained in one compartment and a solvent is contained in the other compartment with a displaceable, moistureproof plug disposed between the two compartments. The closure structure

A closure structure for a vial or container, preferably of the two-compartment type, wherein lyophilized medication is contained in one compartment and a solvent is contained in the other compartment with a displaceable, moistureproof plug disposed between the two compartments. The closure structure is comprised of a stopper which is partially inserted into the neck of a vial and is covered by a cap member having a fastening portion for securing the cap member to the open end of the vial neck and a sleeve portion of reduced diameter which snugly surrounds the protruding portion of the stopper and is disconnectible from the fastening portion in order to move with the protruding portion of the stopper into the neck of the bottle under manually applied pressure. A dust shield is secured to the free end of the sleeve portion and is preferably removed after which the needle of a syringe can be inserted through the stopper to communicate with the interior of the vial.

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