초록 ▼

Method and apparatus suitable for automatic assay of fluid samples, particularly immunoassays, in which a reaction product of the assay is bound to a magnetically attractable particle and separated from the reaction mixture by use of a magnetic trap. The method and apparatus are of especial use in r

Method and apparatus suitable for automatic assay of fluid samples, particularly immunoassays, in which a reaction product of the assay is bound to a magnetically attractable particle and separated from the reaction mixture by use of a magnetic trap. The method and apparatus are of especial use in radioimmunoassays carried out in an automated continuous-flow manner.

대표청구항 ▼

A method of analyzing a plurality of fluid samples for particulate constituents of interest, which comprises the steps of: (a) forming a reaction mixture of each of said fluid samples, each reaction mixture comprising a liquid phase and a solid phase, said solid phase comprising a first reagent boun

A method of analyzing a plurality of fluid samples for particulate constituents of interest, which comprises the steps of: (a) forming a reaction mixture of each of said fluid samples, each reaction mixture comprising a liquid phase and a solid phase, said solid phase comprising a first reagent bound to magnetically attractable particulate material and reactive with the particular constituent to be analyzed in each said fluid sample to form a reaction product, at least on said particulate material; (b) flowing each said reaction mixture in turn and on a discrete basis along a conduit; (c) magnetically trapping said particulate material in each said reaction mixture during flow along a first portion of said conduit, so as to hold said particulate material and thereby separate said solid phase from said liquid phase; and (d) determining the constituent of interest in each said sample by selective analysis of said separated solid phase and/or said separated liquid phase.