초록 ▼

A rechargeable system is provided for the production of sterile, non-pyrogenic, isotonic solutions of radioisotopes such as sodium pertechnetate, which are useful as diagnostic agents in the medical field. A unique feature of the system is that transfer of the recharging supply of the parent isotope

A rechargeable system is provided for the production of sterile, non-pyrogenic, isotonic solutions of radioisotopes such as sodium pertechnetate, which are useful as diagnostic agents in the medical field. A unique feature of the system is that transfer of the recharging supply of the parent isotope from the shipping shield to the generator contained in the generator shield can be effected with minimal exposure to radiation.

대표청구항 ▼

A rechargeable, radioisotope, generator system, comprised of, in combination: (1) a case assembly having contained therein: (a) a portable shipping shield, comprised of, in combination: (i) a main shield having an inner chamber communicating to the exterior of said main shield, said chamber having a

A rechargeable, radioisotope, generator system, comprised of, in combination: (1) a case assembly having contained therein: (a) a portable shipping shield, comprised of, in combination: (i) a main shield having an inner chamber communicating to the exterior of said main shield, said chamber having a tapered portion thereof terminating with a greater diameter at the exterior surface of said main shield, (ii) a closure shield tapered to engage said main shield to provide a radiological safe seal and yet provide conduit means for ingress and egress of liquids, said closure shield having an inner bore traversing its center in alignment with the axis of and about the same diameter of said chamber, (iii) a plug which is slidably mounted within said inner bore and which can be retained in a fixed position therein by a lip on its upper surface which engages a retaining shelf on at least one portion of said closure shield; said plug being retained in place by removable retaining means which when said plug is disengaged from said shelf it can slidably move through at least a portion of said bore and into said inner chamber, (iv) a vial for radioisotopes contained within and in alignment with said chamber and having a piercable septum on at least one end thereof, and (v) conduit and piercing means contained within said chamber for piercing said septum and permitting ingress of eluant from the exterior of said shipping shield and egress of radioisotope from said vial to the exterior of said shipping shield; (b) a shielded generator having means for absorbing and retaining a parent radioisotope from which a daughter radioisotope can be eluted, (c) a reservoir of eluant disposed in said assembly and in close proximity to said shielded generator and shipping shield, and having disposed thereon a sterile, one-way-check valve communicating to the atomosphere, (d) first conduit means communicating from said reservoir to said shipping shield, second conduit means communicating from said shipping shield to said shielded generator, aNd third conduit means communicating from said shielded generator to the exterior of said assembly; (2) a shelf traversing the front exterior of said assembly, a portion of which is shielded by exterior shielding means, (3) a shielded elution vial into which said eluate is dispensed, and (4) filter means disposed at a point between said vial and said third conduit means.