초록 ▼

A unitary, hermetically sealed but pierceable dispensing container, suitable for packaging parenteral solutions, is made from a flexible, generally tubular body of thermoplastic material utilizing a form, fill and seal technique and a movable, composite mandrel that includes a forming ram member for

A unitary, hermetically sealed but pierceable dispensing container, suitable for packaging parenteral solutions, is made from a flexible, generally tubular body of thermoplastic material utilizing a form, fill and seal technique and a movable, composite mandrel that includes a forming ram member for compression molding from within the container a container wall portion which includes a pierceable membrane. The tubular body is closed at one end and terminates at the other end in a draining region having an access aperture or port sealed by a unitary membrane of predetermined thickness. The membrane permits penetration of a cannula therethrough without coring, and an annular sealing means surrounding the aperture is adapted for frictional and sealing engagement of the cannula after the membrane has been penetrated.

대표청구항 ▼

A method of forming, filling and hermetically sealing a pierceable container having a desired content which comprises the steps of providing an open assembly of sectional mold parts defining a container-forming mold cavity therein when closed; extruding a parison in the form of a semi-solid, elongat

A method of forming, filling and hermetically sealing a pierceable container having a desired content which comprises the steps of providing an open assembly of sectional mold parts defining a container-forming mold cavity therein when closed; extruding a parison in the form of a semi-solid, elongated hollow tube between said mold parts; severing a predetermined tube length from the parison to provide an access opening into the severed tube length for receiving a composite mandrel which includes a blowing and filling nozzle and a forming ram member; closing said assembly about said severed predetermined tube length so as to confine a portion of the tube length between the mold parts and within said container-forming cavity while closing one end of the confined tube length and permitting the access opening to remain open at the other end of the tube length; positioning said composite mandrel so as to close the access opening blade and blow-forming said tube length so as to provide semi-solid walls defining said container; forming a pierceable wall region of predetermined dimensions in said container by urging said forming ram member against a selected semi-solid wall region of the blow-formed container so as to compressively mold from within the blow-formed container a wall region of predetermined dimensions; filling the blow-formed container with the desired contents through said composite mandrel; retracting said forming ram member from said selected wall region; providing forming and sealing means for closing the open end of said confined tube length so as to hermetically seal the filled container; operating said forming and sealing means to hermetically seal the filled container; and opening said assembly to remove the filled and hermetically-sealed but pierceable container.