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Non-immunogenic polypeptides 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07G-007/00
  • C07G-007/02
  • A61K-037/26
  • A61K-037/48
출원번호 US-0819831 (1977-07-28)
발명자 / 주소
  • Davis Frank F. (19 Farmingdale Rd. East Brunswick NJ 08816) Van Es Theodorus (313 Overbrook Rd. Piscataway NJ 08854) Palczuk Nicholas C. (45 W. Franklin St. Bound Brook NJ 08805)
인용정보 피인용 횟수 : 1291  인용 특허 : 3

초록 ▼

Polypeptides such as enzymes and insulin are coupled to polyethylene glycol or polypropropylene glycol having a molecular weight of 500 to 20,000 daltons to provide a physiologically active non-immunogenic water soluble polypeptide composition. The polyethylene glycol or polypropylene glycol protect

대표청구항 ▼

A physiologically active, substantially non-immunogenic water soluble polypeptide composition comprising, a physiologically active polypeptide coupled with a coupling agent to at least one substantially linear polymer having a molecular weight of between about 500 to about 20,000 daltons selected fr

이 특허에 인용된 특허 (3)

  1. Orth Hans Dieter (Darmstadt DT) Brummer Wolfgang (Darmstadt DT) Klockow Michael (Darmstadt DT) Hennrich Norbert (Darmstadt DT), Carrier matrix for the fixation of biochemically effective substances and process for the preparation thereof.
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  2. Green Joseph (London EN) Cawthorne Michael Anthony (Horsham EN), Fibrinolytic compositions.
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  3. Royer Garfield P. (Worthington OH), Modifying enzymes with polyethylene glycol and product produced thereby.
    상세보기

이 특허를 인용한 특허 (1291)

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  156. Tan, Philip; Simon, Sandy A; Cerveny, Charles G; Nilsson, Christy Anne; Brady, William; Ledbetter, Jeffrey A; Hayden-Ledbetter, Martha S; Thompson, Peter A; Morales, Cecile, CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof.
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  157. Gegg, Jr., Colin V.; Johnson, Eileen J.; Miranda, Leslie P.; Walker, Kenneth W.; Holder, Jerry Ryan; Wright, Marie E.; D'Amico, Derin C., CGRP peptide antagonists and conjugates.
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  158. Fujii, Nobutaka; Tamamura, Hirokazu; Hori, Akira, CXCR4 antagonist and use thereof.
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  159. Ekwuribe, Nnochiri N.; Radhakrishnan, Balasingam, Calcitonin drug-oligomer conjugates, and uses thereof.
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  161. Huang, Bo; Marshall, Margaret Ann, Cancer treatment.
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  164. Zhou, Mingdong, Cardiac muscle function and manipulation.
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  170. Anderson, Dirk M, Cells and methods for producing blocking antibodies to human RANKL.
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  172. Inoue Masayasu (Kumamoto JPX) Maeda Hiroshi (Kumamoto JPX), Chemically modified bilirubin oxidase.
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  173. Kinstler, Olaf; Gegg, Colin; Freeman, Aimee; Boone, Thomas, Chemically modified novel erythropoietin stimulating protein compositions and methods.
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  180. Crowe, Brian A.; Livey, Ian; O'Rourke, Maria; Schwendinger, Michael, Chimeric OspA genes, proteins and methods of use thereof.
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  185. Sonoda, Junichiro, Chimeric fibroblast growth factors with altered receptor specificity.
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  186. Erickson, Mary, Chimeric leptin polypeptide and method of using the same.
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  187. Li, Yang; Wu, Xinle; Wang, Zhulun, Chimeric polypeptides and uses thereof.
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  188. Nakayama, Naoki; Wen, Duanzhi; Han, Chun-ya; He, Ching; Yu, Dongyin, Chordin-like molecules and uses thereof.
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  191. Theodore Louis J. ; Axworthy Donald B., Cluster clearing agents.
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  193. Schellenberger, Volker; Stemmer, Willem P.; Geething, Nathan C.; To, Wayne; Silverman, Joshua; Wang, Chia-wei; Spink, Benjamin, Coagulation factor IX compositions and methods of making and using same.
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  195. Persson,Egon, Coagulation factor VII derivatives.
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  196. Caldwell Karin Maria Elisabet ; Carlsson Per Jan Erik,SEX ; Li Jenq-Thun, Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligan.
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  198. Tuaillon, Nadine; Rankin, Christopher, Combination of FcγRIIB-specific antibodies and CD20-specific antibodies and methods of use thereof.
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  210. Rhee, Woonza M.; DeLustro, Frank A.; Berg, Richard A., Composition for administration of a biologically active compound.
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  218. Lazar, Gregory A.; Moore, Gregory L., Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens.
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  220. Simonet, Scott; Sarosi, Ildiko, Compositions and methods for the prevention and treatment of cardiovascular diseases.
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  223. Morris, David W.; Engelhard, Eric K., Compositions and methods in cancer associated with altered expression of KCNJ9.
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  224. Morris, David W.; Engelhard, Eric K., Compositions and methods in cancer associated with altered expression of PRLR.
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  225. Daniloff, George Y.; Sehl, Louis C.; Trollsas, Olof Mikael; Schroeder, Jacqueline A.; Gravett, David M.; Toleikis, Philip M., Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use.
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  228. Olof Mikael Trollsas ; Donald G. Wallace ; Frank A. DeLustro, Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use.
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  230. Harris, J. Milton; Kozlowski, Antoni; McManus, Samuel P.; Bentley, Michael D.; Charles, Stephen A., Compositions comprising a polymeric reagent and a pharmacologically active agent.
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  231. Barrett, P. Noel; Aichinger, Gerald; Crowe, Brian A.; Livey, Ian; Wressnigg, Nina, Compositions comprising chimeric OSPA molecules and methods of use thereof.
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  232. Bossard, Mary J., Compositions comprising two different populations of polymer-active agent conjugates.
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  233. Zhao, Allan Z., Compositions for blocking the inhibitory effect of human CRP on human leptin.
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  234. Yaspan, Brian; Graham, Robert Royal; Dressen, Amy; Li, Zhengrong; Strauss, Erich; Bugawan, Teodorica, Compositions for detecting complement factor H (CFH) and complement factor I (CFI) polymorphisms.
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  235. Winslow, Robert M.; Vandegriff, Kim D., Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin.
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  237. Kriegler Michael ; Perez Carl ; Halenbeck Robert F. ; Jewell David A. ; Koths Kirston E., Compositions for the inhibition of TNF hormone formation and uses thereof.
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  238. Thanos, Christopher D.; Wang, Lin; Shepard, H. Michael, Compositions of adenosine deaminase-2 (ADA2), variants thereof and methods of using same.
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  239. Patton, John S.; Kuo, Mei-Chang; Harris, J. Milton; Leach, Chester; Perkins, Kimberly; Bueche, Blaine, Compositions of chemically modified insulin.
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  240. Mosberg, Henry I., Compound and method for modulating opioid receptor activity.
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  242. Bloom, Stephen Robert, Compounds and their effects on feeding behaviour.
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  245. Duocastella Codina, Lluis; Molina, Maria; Arad, Ofir; Borrell Bilbao, Jose Ignacio; Garcia, David Sanchez; Petterson Salom, Sofia Henriette, Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers.
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  246. Block, Lutz-Henning, Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension.
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  247. Zalipsky,Samuel; Gabizon,Alberto A., Conjugate having a cleavable linkage for use in a liposome.
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  248. Zalipsky,Samuel; Gabizon,Alberto A., Conjugate having a cleavable linkage for use in a liposome.
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  249. Camble Roger,GB2 ; Timms David,GB2 ; Wilkinson Anthony James,GB2, Conjugate of a solution stable G-CSF derivative and a water-soluble polymer.
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  250. Bolt, Gert; Vandahl, Brian Berg Stidsen; Thim, Lars; Stennicke, Henning Ralf; Steenstrup, Thomas Dock; DeFrees, Shawn, Conjugated factor VIII molecules.
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  251. Gengrinovitch, Stela; Izakovich, Esther, Conjugates for cancer therapy and diagnosis.
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  252. Gengrinovitch, Stela; Izakovich, Esther, Conjugates for cancer therapy and diagnosis.
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  253. Bos, Ebo Sijbren; De Kort, Martin; Smit, Meertinus Jan; Van Boeckel, Constant Adriaan Anton, Conjugates of a polypeptide and a pentasaccharide.
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  254. Eichner, Wolfram; Schimmel, Martin; Hacket, Frank; Kraus, Elmar; Zander, Norbert; Frank, Ronald; Conradt, Harald; Langer, Klaus; Orlando, Michele; Sommermeyer, Klaus, Conjugates of hydroxyalkyl starch and a protein.
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  255. Eichner, Wolfram; Schimmel, Martin; Hacket, Frank; Kraus, Elmar; Zander, Norbert; Frank, Ronald; Conradt, Harald; Langer, Klaus; Orlando, Michele; Sommermeyer, Klaus, Conjugates of hydroxyalkyl starch and a protein.
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  256. Eichner, Wolfram; Orlando, Michele; Zander, Norbert; Conradt, Harald S.; Hacket, Frank; Langer, Klaus; Frank, Ronald, Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination.
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  257. Sommermeyer, Klaus; Eichner, Wolfram; Frie, Sven; Jungheinrich, Cornelius; Scharpf, Roland; Lutterbeck, Katharina; Hemberger, Jurgen; Orlando, Michele, Conjugates of hydroxyalkyl starch and an active agent.
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  258. Garman Andrew J. (Betchworth GBX), Conjugates of pharmaceutically useful proteins.
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  259. Saifer Mark (Berkeley CA) Somack Ralph (Oakland CA) Williams L. David (Fremont CA), Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols.
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  260. Shadle Paula J. (Richmond CA) Koths Kirston E. (El Cerrito CA) Moreland Margaret (Berkeley CA) Katre Nandini (El Cerrito CA), Conjugation of polymer to colony stimulating factor-1.
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  261. Bisgard-Frantzen Henrik,DKX ; Olsen Arne Agerlin,DKX ; Prento Annette,DKX, Conjugation of polypeptides.
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  262. Camble, Roger; Timms, David; Wilkinson, Anthony J., Continuous release pharmaceutical compositions.
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  263. Southard, Jeffrey L.; Southard, George L., Controlled release CGRP delivery composition for cardiovascular and renal indications.
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  264. Orlando, Michele; Hemberger, Jurgen; Sommermeyer, Klaus; Eichner, Wolfram; Frie, Sven; Lutterbeck, Katharina; Jungheinrich, Cornelius; Scharpf, Roland, Coupling low-molecular substances to a modified polysaccharide.
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  265. Hemberger, Jurgen; Orlando, Michele; Sommermeyer, Klaus; Eichner, Wolfram; Frie, Sven; Lutterbeck, Katharina; Jungheinrich, Cornelius; Scharpf, Roland, Coupling proteins to a modified polysaccharide.
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  266. Hemberger, Jurgen; Orlando, Michele; Sommermeyer, Klaus; Eichner, Wolfram; Frie, Sven; Lutterbeck, Katharina; Jungheinrich, Cornelius; Scharpf, Roland, Coupling proteins to a modified polysaccharide.
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  284. Ni, Jian; Rosen, Craig A.; Pan, James G.; Gentz, Reiner L.; Dixit, Vishva M., Death domain containing receptor 4.
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  305. Lanzavecchia, Antonio, Dengue virus neutralizing antibodies and use thereof.
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  306. Madsen, Peter; Tagmose, Tina Moeller; Naver, Helle; Kjeldsen, Thomas Boerglum, Derivative of an insulin analogue.
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  307. Ho, Guan Huei; Yang, Tou Hsiung; Yang, Jeng, Dietary products comprising one or more of γ-polyglutamic acid (γ-PGA, H form) and γ-polyglutamates for use as nutrition supplements.
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  314. Hsu, Jeff; Masat, Linda; Abraham, Judy; Handa, Masahisa; Schleyer, Siew, EPHB3-specific antibody and uses thereof.
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  317. Stavenhagen, Jeffrey; Koenig, Scott, Engineering Fc antibody regions to confer effector function.
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  318. Zalipsky Samuel ; Woodle Martin C. ; Martin Francis J. ; Barenholz Yechezkel,ILX, Enhanced circulation effector composition and method.
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  323. Nho Kwang (Somerset NJ), Enhancement of antitumor therapy with hemoglobin-based conjugates.
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  324. Ekwuribe, Nnochiri N.; Rhadakrishnan, Balasingam; Price, Christopher H.; Anderson Jr., Wes; Ansari, Aslam M., Enkephalin conjugates.
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  325. Harrison, Jr., Roger G.; Krais, John J., Enzyme conjugate and prodrug cancer therapy.
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  329. Bailon, Pascal Sebastian, Erythropoietin conjugates.
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  330. Duliege, Anne Marie; Stead, Richard; Leuther, Kerstin; Woodburn, Kathryn; Naso, Robert Barnett, Erythropoietin receptor peptide formulations and uses.
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  336. Prickett, Kathryn S.; Young, Andrew A., Exendins and exendin agonists modified with albumin.
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  338. Wei, Ge; Selvam, Krishnasamy Panneer; Bookbinder, Louis; Frost, Gregory I., Extended soluble PH20 polypeptides and uses thereof.
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  340. Belouski, Edward John; Ellison, Murielle Marie; Hamburger, Agnes Eva; Hecht, Randy Ira; Li, Yue-Sheng; Michaels, Mark Leo; Sun, Jeonghoon; Xu, Jing, FGF mutants with reduced proteolysis and aggregation.
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  343. Belouski, Edward John; Ellison, Murielle Marie; Hamburger, Agnes Eva; Hecht, Randy Ira; Li, Yue-Sheng; Michaels, Mark Leo; Sun, Jeonghoon; Xu, Jing, FGF21 mutants and uses thereof.
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  344. Belouski, Edward John; Ellison, Murielle Marie; Hamburger, Agnes Eva; Hecht, Randy Ira; Li, Yue-Sheng; Michaels, Mark Leo; Sun, Jeonghoon; Xu, Jing, FGF21 mutants and uses thereof.
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  345. Belouski, Edward John; Ellison, Murielle Marie; Hamburger, Agnes Eva; Hecht, Randy Ira; Li, Yue-Sheng; Michaels, Mark Leo; Sun, Jeonghoon; Xu, Jing, FGF21 mutants comprising a mutation at position 98, 171 and/or 180.
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  346. Belouski, Edward John; Ellison, Murielle Marie; Hamburger, Agnes Eva; Hecht, Randy Ira; Li, Yue-Sheng; Michaels, Mark Leo; Sun, Jeonghoon; Xu, Jing, FGF21 mutants multimers and uses thereof.
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  347. Belouski, Edward John; Ellison, Murielle Marie; Hamburger, Agnes Eva; Hecht, Randy Ira; Li, Yue-Sheng; Michaels, Mark Leo; Sun, Jeonghoon; Xu, Jing, FGF21 polypeptides comprising two or more mutations.
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  348. Belouski, Edward John; Ellison, Murielle Marie; Hamburger, Agnes Eva; Hecht, Randy Ira; Li, Yue-Sheng; Michaels, Mark Leo; Sun, Jeonghoon; Xu, Jing, FGF21 polypeptides comprising two or more mutations and uses thereof.
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  349. Robson, Tracy; Valentine, Andrea; O'Rourke, Martin Gerard; Hirst, David, FKBP-L and uses thereof.
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  350. Bossard, Mary J.; Stephenson, Gayle, Factor IX moiety-polymer conjugates having a releasable linkage.
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  351. DeFrees,Shawn; Zopf,David; Bayer,Robert; Bowe,Caryn; Hakes,David James; Chen,Xi, Factor IX: remolding and glycoconjugation of Factor IX.
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  352. DeFrees, Shawn; Zopf, David; Bayer, Robert; Bowe, Caryn; Hakes, David; Chen, Xi, Factor VII: remodeling and glycoconjugation of Factor VII.
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  353. Chhabra, Ekta Seth; Liu, Tongyao; Chang, Pei-yun; Peters, Robert T.; Kulman, John, Factor VIII complex with XTEN and von Willebrand Factor protein, and uses thereof.
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  354. Bossard, Mary J.; Bentley, Michael D.; Zhang, Ping, Factor VIII compositions.
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  355. Turecek, Peter; Siekmann, Juergen, Factor VIII polymer conjugates.
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  356. Turecek, Peter; Siekmann, Juergen, Factor VIII polymer conjugates.
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  357. Turecek, Peter; Siekmann, Juergen, Factor VIII polymer conjugates.
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  358. Turecek, Peter; Siekmann, Juergen, Factor VIII polymer conjugates.
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  359. Turecek, Peter; Siekmann, Juergen, Factor VIII polymer conjugates.
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  360. Turecek, Peter; Siekmann, Juergen, Factor VIII polymer conjugates.
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  361. DeFrees,Shawn; Zopf,David; Bayer,Robert; Bowe,Caryn; Hakes,David; Chen,Xi, Factor VIII remodeling and glycoconjugation of Factor VIII.
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  362. DeFrees, Shawn; Zopf, David A.; Bayer, Robert J.; Bowe, Caryn; Hakes, David James; Chen, Xi, Factor VIII: remodeling and glycoconjugation of factor VIII.
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  363. Turecek, Peter; Siekmann, Juergen; Scheiflinger, Friedrich; Canavaggio, Michel, Factor VIIa-polysialic acid conjugate having prolonged in vivo half-life.
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  364. Radhakrishnan, Balasingam; Aggarwal, Diti; Ferro, Michelle; James, Kenneth D.; Malkar, Navdeep B.; Miller, Mark A.; Pavliv, Leo; Polowy, Karen; Puskas, Monica; Ekwuribe, Nnochiri N., Fatty acid formulations and oral delivery of proteins and peptides, and uses thereof.
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  365. Radhakrishnan, Balasingam; Aggarwal, Diti; Ferro, Michelle; James, Kenneth D.; Malkar, Navdeep B.; Miller, Mark A.; Pavliv, Leo; Polowy, Karen; Puskas, Monica; Ekwuribe, Nnochiri N., Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof.
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  366. Johnson, Leslie S.; Rainey, Godfrey Jonah Anderson; Gorlatov, Sergey; Lerner, Laura, Fc region-containing polypeptides that exhibit improved effector function due to alterations of the extent of fucosylation, and methods for their use.
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  367. Koenig,Scott; Veri,Maria Concetta, FcγRIIB specific antibodies and methods of use thereof.
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  368. Koenig,Scott; Veri,Maria Concetta, FcγRIIB-specific antibodies and methods of use thereof.
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  369. Johnson, Leslie S.; Huang, Ling, FcγRIIB specific antibodies and methods of use thereof.
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  370. Johnson, Leslie S.; Huang, Ling, FcγRIIB specific antibodies and methods of use thereof.
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  371. Koenig, Scott; Veri, Maria Concetta, FcγRIIB specific antibodies and methods of use thereof.
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  372. Koenig, Scott; Veri, Maria Concetta, FcγRIIB specific antibodies and methods of use thereof.
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  373. Koenig, Scott; Veri, Maria Concetta; Tuaillon, Nadine, FcγRIIB specific antibodies and methods of use thereof.
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  374. Koenig, Scott; Veri, Maria Concetta; Tuaillon, Nadine; Bonvini, Ezio, FcγRIIB specific antibodies and methods of use thereof.
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  375. Koenig, Scott; Veri, Maria Concetta; Tuaillon, Nadine; Bonvini, Ezio, FcγRIIB specific antibodies and methods of use thereof.
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  376. Koenig, Scott; Veri, Maria Concetta; Tuaillon, Nadine; Bonvini, Ezio, FcγRIIB specific antibodies and methods of use thereof.
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  377. Johnson, Leslie S.; Huang, Ling; Gerena, Robyn, FcγRIIB-specific antibodies and methods of use thereof.
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  378. Johnson, Leslie S.; Huang, Ling; Gerena, Robyn, FcγRIIB—specific antibodies and methods of use thereof.
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  379. Arvedson, Tara; Dyas, Gregory; Rottman, James B.; Sasu, Barbra; Bi, Xiao-juan; Lee, Grace Ki Jeong; Sheng, Jackie Z., Ferroportin antibodies and methods of use.
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  380. Arvedson, Tara; Dyas, Gregory; Rottman, James B.; Sasu, Barbra; Bi, Xiao-juan; Lee, Grace Ki Jeong; Sheng, Jackie Z., Ferroportin antibodies and methods of use.
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  381. Hunter Robert L. (3640 Churchwell Ct. Tucker GA 30084) Duncan Alexander (1756 Corners Cove Dunwoody GA 30338), Fibrinolytic composition.
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  382. Thomason, Arlen; Liu, Benxian, Fibroblast growth factor-like polypeptides.
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  383. Thomason,Arlen Read; Liu,Benxian, Fibroblast growth factor-like polypeptides.
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  384. Thomason,Arlen; Liu,Benxian; Danilenko,Dimitry Michael, Fibroblast growth factor-like polypeptides.
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  386. Thomason, Arlen; Liu, Benxian, Fibroblast growth factor-like polypeptides and variants thereof.
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  387. Clark, Richard A.; Ren, Xiang-Dong; Lin, Fubao, Fibronectin polypeptides and methods of use.
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  388. Hill, Jennifer J.; Wolfman, Neil M., Follistatin domain containing proteins.
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  389. Bandyopadhyay, Sanjay; Natarajan, Venkatesan; Mendiratta, Sanjeev Kumar; Patel, Pankaj Ramanbhai, Formulations of PEG-interferon alpha conjugates.
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  390. Bolognesi,Dani Paul; Matthews,Thomas James; Wild,Carl T.; Barney,Shawn O'Lin; Lambert,Dennis Michael; Petteway,Stephen Robert; Langlois,Alphonse J., Fusion proteins comprising DP-178 and other viral fusion inhibitor peptides useful for treating aids.
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  391. Hill, Jennifer J.; Wolfman, Neil M., GASP1: a follistatin domain containing protein.
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  392. Hill, Jennifer J.; Wolfman, Neil M., GASP1: a follistatin domain containing protein.
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  393. Hill,Jennifer J.; Wolfman,Neil M., GASP1: a follistatin domain containing protein.
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  394. Glaesner, Wolfgang; Mayer, John Philip; Millican, Jr., Rohn Lee; Vick, Andrew Mark; Zhang, Lianshan, GLP-1 pegylated compounds.
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  395. DeFrees,Shawn; Zopf,David; Bayer,Robert; Bowe,Caryn; Hakes,David; Chen,Xi, Galactosyl nucleotide sugars.
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  396. Chan, Vivien W.; Escobedo, Jaime; Garcia, Pablo Dominguez; Hansen, Rhonda; Kaufmann, Joerg; Kennedy, Giulia C.; Lamson, George; Moler, Edward J.; Randazzo, Filippo; Reinhard, Christoph; Sudduth-Klinger, Julie, Gene products differentially expressed in cancerous cells.
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  405. DeFrees, Shawn; Bayer, Robert J.; Zopf, David A., Glycopegylated erythropoietin.
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  406. DeFrees, Shawn; Zopf, David A.; Bowe, Caryn Lang, Glycopegylated erythropoietin.
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  566. Hinderer, Walter; Scheckermann, Christian, Liquid formulation of G-CSF conjugate.
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  567. Reslow, Mats, Liquid formulations N-terminal serine of pegylated growth hormone.
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  576. Shayman, James A.; Abe, Akira; Kelly, Robert; Kollmeyer, Jessica; Lu, Ye, Lysosomal phospholipase A2 (LPLA2) activity as a diagnostic and therapeutic target for identifying and treating systemic lupus erythematosis.
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  579. Barnikol, Wolfgang, Mammalian haemoglobin compatible with blood plasma, cross-linked and conjugated with polyalkylene oxides as artificial medical oxygen carriers, production and use thereof.
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  583. Siekmann, Juergen; Sheinecker, Richard; Rottensteiner, Hanspeter; Turecek, Peter, Materials and methods for conjugating a water soluble fatty acid derivative to a protein.
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  585. Garnett, Martin Charles; Davis, Stanley Stewart; Bignotti, Fabio; Ferruti, Paolo, Method for attaching polyethylene glycol to macromolecules.
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  586. Chen, Tingchao; Zhao, Yi; Anderson, W. French, Method for bone marrow preservation or recovery.
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  587. Frost, Gregory I.; Bilinsky, Igor; Vaughn, Daniel; Sugarman, Barry, Method for control of post-prandial glucose.
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  589. Havelund, Svend; Jensen, Simon Bjerregaard, Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein.
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  594. Barnikol Wolfgang,DEX, Method for obtaining uniform fractions of hyperpolymeric hemoglobins.
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  599. Rhee, Woonza M.; DeLustro, Frank A.; Berg, Richard A., Method for preventing the formation of adhesions following surgery or injury.
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  602. Olsen Arne Agerlin,DKX ; Hansen Lars Bo,DKX ; Beck Thomas Christian,DKX, Method for reducing respiratory allergenicity.
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  603. Buchardt, Jens; Langeland Johansen, Nils, Method for selectively modifying a protein via transglutaminase catalyzed reaction.
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  605. Boehm, Gerald; Esser, Dirk, Method for transfer of molecular substances with prokaryotic nucleic acid-binding proteins.
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  608. Zalipsky,Samuel; Gabizon,Alberto, Method for treating multi-drug resistant tumors.
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  610. Stevens Vernon C., Method for treatment of antigenically modified polypeptides.
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  615. Hunter Robert L. (Tucker GA), Method of delivering drugs to damaged or diseased tissue.
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  617. Huang, Jung San; Huang, Shuan Shian, Method of enhancing TGF-β signalling.
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  618. Matthews William ; Austin Timothy W., Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides.
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  619. Ranade,Koustubh; Delmonte,Terrye Aigeldinger; Geese,William J., Method of identifying a PPARgamma-agonist compound having a decreased likelihood of inducing dose-dependent peripheral edema.
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  620. Basile, Lena A., Method of increasing survival of a human subject having exposure to an acute exposure to non-therapeutic whole body ionization by administering a therapeutically effective dose of IL-12.
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  622. Weiss, Stephen J.; Rowe, Robert G., Method of modulating neovascularization.
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  626. Goldenberg David M. (Short Hills NJ), Method of reducing immunogenicity.
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  627. Hunter Robert L. (Tucker GA), Method of treating adult respiratory distress syndrome.
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  628. Hunter Robert L. (Tucker GA), Method of treating burns.
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  629. Waldman, Scott A.; Magee, Michael S.; Snook, Adam E., Method of treating cancer by administering chimeric antigen receptor comprising anti-GCC antibody.
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  630. Klima,Horst; Lehmann,Paul; Roeddiger,Ralf; Walter Matsui,Ruth, Method of treating disturbances of iron distribution in inflammatory intestinal diseases.
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  631. Sexton, Daniel J.; Viswanathan, Malini, Method of treating hereditary angioedema using plasma kallikrein binding antibodies.
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  632. Hunter Robert L. (Tucker GA), Method of treating mycardial damage.
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  633. Hunter Robert L. (Tucker GA), Method of treating tissue damaged by reperfusion injury.
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  634. Bentires-Alj, Mohamed; Aceto, Nicola; Stadler, Michael, Method of treatment of breast cancers over-expressing the SHP2 signature genes.
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  635. Clark,Mike A., Method of treatment with modified arginine deiminase.
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  637. Kim, Sung K.; Deciu, Cosmin, Methods and compositions for analyzing nucleic acid.
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  639. Robert M. Winslow, Methods and compositions for optimization of oxygen transport by cell-free systems.
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  642. Sukhatme, Vikas P.; Zon, Leonard I.; Galloway, Jenna, Methods and compositions for the treatment and diagnosis of endothelial cell disorders and angiogenic disorders.
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  643. Hunter Robert L. (Tucker GA), Methods and compositions for treatment of pathological hydrophobic interactions in biological fluids.
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  644. Chevrier, Marc; Freimuth, William W.; Zhong, Zhenshao; Odenheimer, Daniel, Methods and compositions for use in treatment of patients with autoantibody positive disease.
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  645. Martin, Flavius, Methods and compositions related to B cell assays.
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  646. Rosario-Jansen, Theresa; Wright, David Erick, Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during PEGylated uricase therapy.
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  647. Cantor, Charles R.; DeSantis, Grace; Mueller, Reinhold; Ehrich, Mathias, Methods and processes for non-invasive assessment of genetic variations.
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  648. Donnelly, Mark; Eschenfeldt, William H.; Trent, Jonathan, Methods for converting glucose to ascorbic acid.
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  649. Sabbadini, Roger A., Methods for decreasing immune response and treating immune conditions.
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  650. Ekwuribe, Nnochiri N.; Rhadakrishnan, Balasingam; Price, Christopher H.; Anderson Jr., Wes; Ansari, Adam M., Methods for delivering therapeutics across blood-barrier and for altering receptor binding affinity.
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  652. Harris, J. Milton; Kozlowski, Antoni; McManus, Samuel P.; Bentley, Michael D.; Charles, Stephen A., Methods for forming polymer-drug conjugates.
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  653. Braun, Andreas; Koster, Hubert; Van den Boom, Dirk; Yip, Ping; Rodi, Charles; He, Liyan; Chiu, Norman; Jurinke, Christiane, Methods for generating databases and databases for identifying polymorphic genetic markers.
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  654. Braun, Andreas; Köster, Hubert; Van Den Boom, Dirk Johannes; Yip, Ping; Rodi, Charles; He, Liyan; Chiu, Norman; Jurinke, Christian, Methods for generating databases and databases for identifying polymorphic genetic markers.
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  656. Young, Andrew A.; Gedulin, Bronislava, Methods for glucagon suppression.
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  657. Young,Andrew A.; Gedulin,Bronislava, Methods for glucagon suppression using modified exendins.
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  659. Yamaguchi,Kyoji; Yasuda,Hisataka; Nakagawa,Nobuaki; Shima,Nobuyuki; Kinosaki,Masahiko; Tsuda,Eisuke; Goto,Masaaki; Yano,Kazuki; Tomoyasu,Akihiro; Kobayashi,Fumie; Washida,Naohiro; Takahashi,Ken; Mori, Methods for identifying a substance which specifically binds to an osteoclastogenesis inhibitory factor-binding molecule and modulates the biological activity thereof.
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  660. Huang, Shuan Shian; Huang, Jung San, Methods for inhibiting TGF-β.
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  661. Clark,Mike, Methods for inhibiting viral replication in vivo.
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  662. Anderson, Dirk M, Methods for interfering with rank signaling.
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  663. Hartman, Jacob; Mendelovitz, Simona; Rehrig, Claudia D.; Huang, William; Hershfield, Michael, Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase.
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  664. Peled, Amnon; Begin, Michal; Beider, Katia; Abraham, Michal, Methods for obtaining a therapeutically effective amount of hematopoietic precursor cells and long term engraftment thereof.
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  665. Winslow, Robert M.; Vandegriff, Kim D., Methods for oxygen transport comprising a high oxygen affinity modified hemoglobin.
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  666. Cicardi, Marco; Bergamaschini, Luigi, Methods for preserving organs and tissues.
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  671. Basile, Lena A., Methods for radiation protection by administering IL-12.
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  672. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Methods for reducing intraocular pressure by administering a soluble hyaluronidase glycoprotein (sHASEGP).
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  674. Stavenhagen, Jeffrey B.; Koenig, Scott, Methods for the treatment of disease using immunoglobulins having Fc Regions with altered affinities for FcγRactivating and FcγRinhibiting .
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  675. Stavenhagen, Jeffrey B.; Koenig, Scott, Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for FcγRactivating and FcγRinhibiting.
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  676. Sehl, Louis C.; Trollsas, Olof Mikael; Wallace, Donald G.; Toman, David; DeLustro, Frank A.; Schroeder, Jacqueline A.; Chu, George H., Methods for tissue repair using adhesive materials.
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  677. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Methods for treating a disease characterized by an excess of hyaluronan by administering a soluble hyaluronidase glycoprotein (sHASEGP).
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  678. Jin, Jian-Ping, Methods for treating cardiac disease by modifying an N-terminal domain of troponin I.
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  679. Marchionni, Mark; Kelly, Ralph; Lorell, Beverly; Sawyer, Douglas B., Methods for treating congestive heart failure.
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  680. Marchionni, Mark; Kelly, Ralph; Lorell, Beverly; Sawyer, Douglas B., Methods for treating congestive heart failure.
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  683. Thomason, Arlen; Liu, Benxian, Methods for treating diabetes using fibroblast growth factor-like polypeptides.
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  686. Thomason, Arlen; Liu, Benxian, Methods for treating obesity using fibroblast growth factor-like polypeptides.
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  687. Thomason, Arlen; Liu, Benxian, Methods for treating obesity using fibroblast growth factor-like polypeptides.
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  688. Peters, Kevin; Shalwitz, Robert, Methods for treating vascular leak syndrome and cancer.
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  689. Goto,Masaaki; Tsuda,Eisuke; Mochizuki,Shin'ichi; Yano,Kazuki; Kobayashi,Fumie; Shima,Nobuyuki; Yasuda,Hisataka; Nakagawa,Nobuaki; Morinaga,Tomonori; Ueda,Masatsugu; Higashio,Kanji, Methods for using the osteoclastogenesis inhibitory factor (OCIF) protein.
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  690. Ekwuribe, Nnochiri N.; Radhakrishnan, Balasingam; Price, Christopher H.; Anderson, Jr., Wes; Ansari, Aslam M., Methods of activating a receptor using amphiphilic drug-oligomer conjugates.
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  691. Hsei, Vanessa; Koumenis, Iphigenia; Leong, Steven; Shahrokh, Zahra; Zapata, Gerardo, Methods of binding TNF-α using anti-TNF-α antibody fragment-polymer conjugates.
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  692. Migone, Thi-Sau; Klein, Jerry L.; Oki, Yasuhiro; Younes, Anas, Methods of diagnosing and prognosing hodgkin's lymphoma.
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  693. Pelleymounter, Mary Ann; Toombs, Christopher Francis; Mann, Michael Benjamin, Methods of increasing lean tissue mass using OB protein compositions.
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  695. MacDonald, Brian R.; Kaushansky, Kenneth, Methods of increasing platelet and hematopoietic stem cell production.
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  702. Rudolph, Alfred R.; Tuthill, Cynthia W., Methods of protecting against radiation damage using alpha thymosin.
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  703. Yamaguchi, Kyoji; Yasuda, Hisataka; Nakagawa, Nobuaki; Shima, Nobuyuki; Kinosaki, Masahiko; Tsuda, Eisuke; Goto, Masaaki; Yano, Kazuki; Tomoyasu, Akihiro; Kobayashi, Fumie; Washida, Naohiro; Takahashi, Ken; Morinaga, Tomonori; Higashio, Kanji, Methods of reducing bone absorption comprising administering an antibody that binds OBM.
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  704. Still, James Gordon; Kosutic, Gordana, Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus.
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  705. Soltero, Richard; Radhakrishnan, Balasingam; Ekwuribe, Nnochiri N., Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same.
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  706. Ekwuribe, Nnochiri N.; Price, Christopher H.; Ansari, Aslam M.; Odenbaugh, Amy L., Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties.
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  707. Salcedo,Theodora W.; Ruben,Steven M.; Rosen,Craig A.; Albert,Vivian R.; Dobson,Claire; Vaughan,Tristan, Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors.
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  710. , Methods of treating diabetes mellitus.
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  711. Prickett, Kathryn S.; Young, Andrew A., Methods of treating diabetes with albumin-conjugated exendin peptides.
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  716. Belouski, Edward John; Ellison, Murielle Marie; Hamburger, Agnes Eva; Hecht, Randy Ira; Li, Yue-Sheng; Michaels, Mark Leo; Sun, Jeonghoon; Xu, Jing, Methods of treating of diabetes and obesity using FGF21 mutants.
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  735. Cowley, Michael; Cone, Roger; Low, Malcolm; Butler, Andrew; Bloom, Stephen Robert; Small, Caroline Jane; Batterham, Rachel Louise; Ghatei, Mohammad Ali, Modification of feeding behavior.
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  738. Bloom, Stephen Robert; Ghatei, Mohammad Ali; Small, Caroline Jane; Dakin, Catherine Louise, Modification of feeding behaviour.
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  739. Gegg, Colin V.; Walker, Kenneth W.; Miranda, Leslie P.; Xiong, Fei, Modified Fc molecules.
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  749. Moore, Stanley; Ghatei, Mohammad; Bloom, Stephen Robert, Modified PYY (3-36) peptides and their effects on feeding behavior.
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  750. Wolfman, Neil M.; Khor, Soo Peang; Tomkinson, Kathleen N., Modified and stabilized GDF propeptides and uses thereof.
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  753. Allison, Anthony, Modified annexin compositions and methods of using same.
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  755. Allison, Anthony, Modified annexin proteins and methods for preventing thrombosis.
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  756. Allison, Anthony, Modified annexin proteins and methods for their use in organ transplantation.
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  757. Allison,Anthony, Modified annexin proteins and methods for treating vaso-occlusive sickle-cell disease.
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  759. Hoffmann, Ralf; Berthold, Nicole; Nollmann, Friederike, Modified antibiotic peptides having variable systemic release.
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  761. Clark Mike A., Modified arginine deiminase.
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  766. Inada Yuji (Tokyo JPX), Modified lipase.
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  767. Feige,Ulrich, Modified peptides as therapeutic agents.
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  768. Arne Agerlin Olsen DK; Claus von der Osten DK; Kim Vilbour Andersen DK; Steffen Ernst DK; Erwin Ludo Roggen DK, Modified polypeptide.
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  770. Arne Agerlin Olsen DK; Annette Prento DK, Modified protease having 5 to 13 covalently coupled polymeric molecules for skin care.
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  771. Clark, Mike A., Modified tumor necrosis factor.
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  772. Mathis, Luc; Voytas, Daniel F.; Zhang, Feng; Haun, William, Modifying soybean oil composition through targeted knockout of the FAD2-1A/1B genes.
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  780. Hoarty, Michelle Denise; Dhamnaskar, Ketki Ashok; Elbaum, Daniel; Josephson, Kristopher; Larson, Kelley Cronin; Ma, Zhong; Nims, Nathan Ezekiel; Ricardo, Alonso; Seyb, Kathleen; Tang, Guo-Qing; Treco, Douglas A.; Wang, Zhaolin; Ye, Ping; Zheng, Hong; Perlmutter, Sarah Jacqueline; Hammer, Robert Paul, Modulation of complement activity.
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  782. Friedman, Jeffrey M.; Zhang, Yiying; Proenca, Ricardo, Modulators of body weight, corresponding nucleic acids and proteins.
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  785. Bartley Timothy D. ; Bogenberger Jakob M. ; Bosselman Robert A. ; Hunt Pamela ; Kinstler Olaf B. ; Samal Babru B., Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation.
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  786. Goto, Masaaki; Tsuda, Eisuke; Mochizuki, Shin'ichi; Yano, Kazuki; Kobayashi, Fumie; Shima, Nobuyuki; Yasuda, Hisataka; Nakagawa, Nobuaki; Morinaga, Tomonori; Ueda, Masatsugu; Higashio, Kanji, Monoclonal antibodies that bind OCIF.
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  787. Anderson,Dirk M., Monoclonal blocking antibody to human RANKL.
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  788. Harris, J. Milton; Veronese, Francesco Maria; Caliceti, Paola; Schiavon, Oddone, Multi-armed, monofunctional, and hydrolytically stable derivatives of poly (ethylene glycol) and related polymers for modification of surfaces and molecules.
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  792. Dixit, Surjit Bhimarao; D'Angelo, Igor Edmondo Paolo; Poon, David Kai Yuen, Multivalent heteromultimer scaffold design and constructs.
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  799. Jeanplong, Ferenc; McMahon, Christopher David, Myostatin isoform.
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  808. Gabriel,Nancy E.; Farrar,Christine E., N-terminally chemically modified protein compositions and methods.
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  815. Zhou, Mingdong, Neuregulin based methods and compositions for treating cardiovascular disease.
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  828. Greenwald Richard B. ; Martinez Anthony ; Pendri Annapurna, Non-antigenic amine derived polymers and polymer conjugates.
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  840. Brown, Larry R.; Gillis, Kimberly A.; Gallo, Michael V., Nucleic acid microparticles for pulmonary delivery.
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  841. Madison,Edwin L.; Yeh,Jiunn Chern, Nucleic acid molecules encoding a transmembrane serine protease 10, the encoded polypeptides and methods based thereon.
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  844. Thomason, Arlen; Liu, Benxian, Nucleic acid molecules encoding fibroblast growth factor-like polypeptides.
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  846. Madison,Edwin L.; Yeh,Jiunn Chern, Nucleic acid molecules encoding serine protease CVSP14, the encoded polypeptides and methods based thereon.
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  849. Friedman Jeffrey M. ; Zhang Yiying ; Proenca Ricardo ; Maffei Margherita, Nucleic acid primers and probes for the mammalian OB gene.
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  850. Oeth, Paul Andrew; Mahboubi, Payam; Lee, Min Seob, Nucleic acid-based tests for prenatal gender determination.
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  851. Valge-Archer, Viia; Williams, Andrew James; Young, Deborah A.; Whitters, Matthew J.; Collins, Mary; Witek, Joann, Nucleic acids coding for antibodies against human IL-21 receptor and uses therefor.
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  852. Scheer, Justin; Ouyang, Wenjun; Vandlen, Richard; Hass, Philip E.; Stefanich, Eric Gary; Wang, Xiaoting, Nucleic acids encoding IL-22 Fc fusion proteins.
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  853. Brewer, Michael T.; Thompson, Robert C.; Kohno, Tadahiko, Nucleic acids encoding TNF inhibitor and method of production.
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  854. Baciu, Peter C.; Liang, Yanbin; Guu, Jason; Bernett, Matthew; Muchhal, Umesh; Desjarlais, John, Nucleic acids encoding complement component C5 antibodies.
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  855. Madison,Edwin L.; Ong,Edgar O., Nucleic acids encoding endotheliases, endotheliases and uses thereof.
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  857. Fisher, Eric; Edwards, III, Carl; Kieft, Gary, Nucleic acids encoding truncated soluble tumor necrosis factor.
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  858. Haider, Stefan; Ivens, Andreas; Rottensteiner, Hanspeter; Siekmann, Juergen; Turecek, Peter, Nucleophilic catalysts for oxime linkage.
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  865. Mann, Michael B.; Hecht, Randy Ira; Pelleymounter, Mary Ann; Toombs, Christopher Francis, OB fusion protein compositions and methods.
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  870. Friedman Jeffrey M. ; Zhang Yiying ; Proenca Ricardo, OB polypeptides, modified forms and compositions.
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  871. Friedman, Jeffrey M.; Halaas, Jeffrey L.; Gajiwala, Ketan; Burley, Stephen K., OB polypeptides, modified forms and derivatives.
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  872. Pelleymounter, Mary Ann; Hecht, Randy Ira; Mann, Michael Benjamin, OB protein compositions and methods.
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  873. Jeffrey M. Friedman ; Yiying Zhang ; Ricardo Proenca, Ob polypeptides, modified forms and compositions thereto.
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  874. DeFrees, Shawn; Zopf, David A.; Taudte, Susann; Willett, Walter Scott; Bayer, Robert J.; Kalo, Matthew, One pot desialylation and glycopegylation of therapeutic peptides.
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  875. Moore, Gregory; Bernett, Matthew; Rashid, Rumana; Desjarlais, John, Optimized antibody variable regions.
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  876. Barbosa, Maria D.; Chamberlain, Aaron K.; Desjarlais, John R., Optimized proteins that target Ep-CAM.
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  877. Khedkar, Anand; Rangappa, Sharath Kumar Mallapura; Subramani, Ramesh; Dave, Nitesh; Radhakrishnan, Devesh; Shankar, Sundaresh; Chivukula, Sudheer; Ramakrishna, Ranjith; Murthy, Shanmugam Thandava; Pai, Harish Venkatraman; Sengupta, Nilanjan; Melarkode, Ramakrishnan; Iyer, Harish, Orally administrable solid pharmaceutical composition and a process thereof.
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  878. Magruder Judy A. ; Eckenhoff James B. ; Cortese Richard ; Wright Jeremy C. ; Peery John R. ; Pike James B. ; Robinson Urano A. ; Smith Jonathan P. ; Ziemann Lyle E., Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals.
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  879. Boyle William J. ; Lacey David L. ; Calzone Frank J. ; Chang Ming-Shi, Osteoprotegerin.
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  880. Boyle William J. ; Lacey David L. ; Calzone Frank J. ; Chang Ming-Shi, Osteoprotegerin.
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  881. Boyle William J. ; Lacey David L. ; Calzone Frank J. ; Chang Ming-Shi, Osteoprotegerin.
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  882. Boyle William J. ; Lacey David L. ; Calzone Frank J. ; Chang Ming-Shi, Osteoprotegerin.
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  883. Boyle, William J.; Lacey, David L.; Calzone, Frank J.; Chang, Ming Shi, Osteoprotegerin.
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  884. Boyle, William J.; Lacey, David L.; Calzone, Frank J.; Chang, Ming-Shi, Osteoprotegerin.
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  885. William J. Boyle ; David L. Lacey ; Frank J. Calzone ; Ming-Shi Chang, Osteoprotegerin.
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  886. Boyle,William J., Osteoprotegerin binding proteins.
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  887. Nakamura, Teruo; Sekimori, Yasuo; Machida, Minoru; Kawata, Hiromitsu; Miyamoto, Hajime, PEG-conjugated erythropoietin.
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  888. Ensor, Charles Mark; Clark, Mike A.; Holtsberg, Frederick Wayne, PEG-modified uricase.
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  889. Williams, L. David; Hershfield, Michael S.; Kelly, Susan J.; Saifer, Mark G. P.; Sherman, Merry R., PEG-urate oxidase conjugates and use thereof.
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  890. Williams, L. David; Hershfield, Michael S.; Kelly, Susan J.; Saifer, Mark G. P.; Sherman, Merry R., PEG-urate oxidase conjugates and use thereof.
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  891. Williams, L. David; Hershfield, Michael S.; Kelly, Susan J.; Saifer, Mark G. P.; Sherman, Merry R., PEG-urate oxidase conjugates and use thereof.
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  892. Williams, L. David; Hershfield, Michael S.; Kelly, Susan J.; Saifer, Mark G. P.; Sherman, Merry R., PEG-urate oxidase conjugates and use thereof.
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  893. Williams, L. David; Hershfield, Michael S.; Kelly, Susan J.; Saifer, Mark G. P.; Sherman, Merry R., PEG-urate oxidase conjugates and use thereof.
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  894. Beals, John Michael; Cutler, Jr., Gordon Butler; Hansen, Ryan John; Li, Shun; Zhang, Lianshan, PEGylated insulin lispro compounds.
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  895. Madsen, Peter; Kjeldsen, Thomas Børglum; Tagmose, Tina Møller; Jakobsen, Palle, PEGylated, extended insulins.
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  896. Thompson, Robert C.; Brewer, Michael T.; Kohno, Tadahiko, PEGylation reagents and compounds formed therewith.
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  897. Wei, Ge; Shepard, H. Michael; Zhao, Qiping; Connor, Robert James, PH20 polypeptide variants, formulations and uses thereof.
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  898. Damiano, Jason; Luqman, Mohammad; Bedinger, Daniel; Masat, Linda; Mirza, Amer; Nonet, Genevieve, PRLR-specific antibody and uses thereof.
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  899. Mirkin, Chad A.; Seferos, Dwight S.; Giljohann, David A., Particles for detecting intracellular targets.
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  900. Mirkin, Chad A.; Seferos, Dwight; Giljohann, David A., Particles for detecting intracellular targets.
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  901. Park Joonsup ; Quintana Ronald P. ; Hong Bor-shyue ; Asgharian Bahram, Peg-modified proteases and methods of use in contact lens cleaning.
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  902. Brown-Augsburger, Patricia Lea; Kohn, Wayne David, Pegylated PTH as PTH receptor modulators and uses thereof.
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  903. Klausen, Niels Kristian; Bjorn, Soren; Behrens, Carsten; Garibay, Patrick William, Pegylated factor VII glycoforms.
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  904. Siekmann, Juergen; Varadi, Katalin; Gritsch, Herbert; Turecek, Peter, Pegylated factor VIII.
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  905. Siekmann, Juergen; Varadi, Katalin; Gritsch, Herbert; Turecek, Peter, Pegylated factor VIII.
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  906. Bailon Pascal Sebastian ; Campfield Arthur ; Devos Rene,BEX ; Guisez Yves,BEX, Pegylated obese (ob) protein compositions.
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  907. Wang, Zhaolin; Ye, Ping; Ricardo, Alonso; Josephson, Kristopher; Anderson, Paul; Arata, Michelle Denise; Ma, Zhong; Nims, Nathan Ezekiel; Schneider, Eberhard; Schurmann, Gregor; Wagner, Peter; Treco, Douglas A.; Zheng, Hong; Elbaum, Daniel; Boyer, Nicolas Cedric, Peptide and peptidomimetic inhibitors.
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  908. Wang, Zhaolin; Ye, Ping; Ricardo, Alonso; Josephson, Kristopher; Anderson, Paul; Arata, Michelle Denise; Ma, Zhong; Nims, Nathan Ezekiel; Schneider, Eberhard; Schurmann, Gregor; Wagner, Peter; Treco, Douglas A.; Zheng, Hong; Elbaum, Daniel; Boyer, Nicolas Cedric, Peptide and peptidomimetic inhibitors.
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  909. Wang, Zhaolin; Ye, Ping; Ricardo, Alonso; Josephson, Kristopher; Anderson, Paul; Hoarty, Michelle Denise; Ma, Zhong; Nims, Nathan Ezekiel; Schneider, Eberhard; Schurmann, Gregor; Wagner, Peter; Treco, Douglas A.; Zheng, Hong; Elbaum, Daniel; Boyer, Nicolas Cedric, Peptide and peptidomimetic inhibitors.
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  910. Huang, Jung San, Peptide antagonists of TGF-beta family members and therapeutic uses thereof.
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  911. Soares, Christopher J., Peptide antagonists of the calcitonin CGRP family of peptide hormones and their use.
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  912. Balu, Palani, Peptide dimers as agonists of the erythropoientin (EPO) receptor, and associated methods of synthesis and use.
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  913. Balu,Palani, Peptide dimers as agonists of the erythropoietin (EPO) receptor, and associated methods of synthesis and use.
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  914. Newgard, Christopher B.; Stephens, Samuel B.; Schisler, Jonathan C., Peptide therapy for hyperglycemia.
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  915. Abraham, Michal; Peled, Amnon; Eizenberg, Orly, Peptide therapy for increasing platelet levels.
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  916. Bloom, Stephen Robert, Peptide tyrosine tyrosine analogues.
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  917. Wu, Han-Chung; Lin, Chin-Tarng; Lee, Tong-Young; Kuo, Szu-Yao, Peptide-conjugates that bind to VEGF-stimulated or tumor vasculature and methods of treatment.
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  918. Dower, William J.; Barrett, Ronald W.; Cwirla, Steven E.; Duffin, David J.; Gates, Christian M.; Haselden, Sherril S.; Mattheakis, Larry C.; Schatz, Peter J.; Wagstrom, Christopher R.; Wrighton, Nicholas C., Peptides and compounds that bind to a receptor.
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  919. Balu,Palani; Yin,Qun; England,Bruce, Peptides and compounds that bind to the IL-5 receptor.
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  920. Balu,Palani; Yin,Qun; England,Bruce, Peptides and compounds that bind to the IL-5 receptor.
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  921. Peled, Amnon; Wald, Ori, Peptides and use thereof in the treatment of large cell lung cancer.
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  922. Chung, Yong-Ji; Kim, Young Deug; Kim, Eun Mi; Choi, Jun Young; Song, Sang Su, Peptides having activities of epidermal growth factor and its uses.
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  923. Wu, Han-Chung; Lin, Chin-Tarng; Lo, Albert, Peptides specific for hepatocellular carcinoma cells and applications thereof.
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  924. Holmes, Christopher P.; Yin, Qun; Lalonde, Guy; Schatz, Peter J.; Tumelty, David; Balu, Palani; Zemede, Genet, Peptides that bind to the erythropoietin receptor.
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  925. Holmes, Christopher P.; Yin, Qun; Lalonde, Guy; Schatz, Peter J.; Tumelty, David; Balu, Palani; Zemede, Genet, Peptides that bind to the erythropoietin receptor.
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  926. Holmes, Christopher P.; Yin, Qun; Lalonde, Guy; Schatz, Peter J.; Tumelty, David; Palani, Balu; Zemede, Genet, Peptides that bind to the erythropoietin receptor.
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  927. Holmes, Christopher P.; Yin, Qun; Lalonde, Guy; Schatz, Peter J.; Tumelty, David; Palani, Balu; Zemede, Genet, Peptides that bind to the erythropoietin receptor.
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  928. Holmes,Christopher P.; Yin,Qun; Lalonde,Guy; Schatz,Peter J.; Tumelty,David; Palani,Balu; Zemede,Genet, Peptides that bind to the erythropoietin receptor.
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  929. Holmes,Christopher P.; Yin,Qun; Lalonde,Guy; Schatz,Peter J.; Tumelty,David; Palani,Balu; Zemede,Genet, Peptides that bind to the erythropoietin receptor.
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  930. Mezo, Adam R.; McDonnell, Kevin A.; Hehir, Cristina A. Tan; Castro, Alfredo, Peptides that block the binding of IgG to FcRn.
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  931. Mezo, Adam R.; McDonnell, Kevin A.; Hehir, Cristina A. Tan; Castro, Alfredo, Peptides that block the binding of IgG to FcRn.
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  932. Turkson, James; Jove, Richard; Sebti, Said M.; Hamilton, Andrew D., Peptidomimetic inhibitors of STAT activity and uses thereof.
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  933. Turkson,James; Jove,Richard; Sebti,Said M.; Hamilton,Andrew D., Peptidomimetic inhibitors of STAT activity and uses thereof.
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  934. Rudnicki, Michael; Smid, Johnathan, Periostin-induced pancreatic regeneration.
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  935. David John Weisgerber ; Andrew Campbell Allcock, Personal care compositions containing active proteins tethered to a water insoluble substrate.
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  936. Weisgerber David John ; Allcock Andrew Campbell, Personal care compositions containing subtilisin enzymes bound to water insoluble substrates.
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  937. Soltero, Richard; Ekwuribe, Nnochiri N.; Opawale, Foyeke; Rehlaender, Bruce; Hickey, Anthony; Bovet, Li Li, Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith.
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  938. Harris, J. Milton; Kozlowski, Antoni; McManus, Samuel P.; Bentley, Michael D.; Charles, Stephen A., Pharmaceutical compositions of conjugates formed from polymer derivatives having particular atom arrangements.
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  939. Soltero,Richard; Ekwuribe,Nnochiri N.; Opawale,Foyeke; Rehlaender,Bruce; Hickey,Anthony; Bovet,Li Li, Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith.
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  940. DeFrees,Shawn; Zopf,David A.; Bayer,Robert J.; Bowe,Caryn; Hakes,David James; Chen,Xi, Pharmaceutical compositions of glycoconjugates.
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  941. Soltero, Richard; Radhakrishan, Balasingam; Ekwuribe, Nnochiri N.; Rehlaender, Bruce; Hickey, Anthony; Bovet, Li Li, Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith.
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  942. Soltero,Richard; Radhakrishan,Balasingam; Ekwuribe,Nnochiri N.; Rehlaender,Bruce; Hickey,Anthony; Bovet,Li Li, Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith.
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  943. Shaked Ze\ev (Berkeley CA) Stewart Tracy (San Francisco CA) Thomson James W. (Albany CA) Hirtzer Pamela (Oakland CA), Pharmaceutical compositions of recombinant interleukin-2 and formulation processes.
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  944. Cottingham, Ian; Plaksin, Daniel; Aharanov, Jenny, Pharmaceutical preparation.
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  945. Orlando, Michele; Hemberger, Jurgen; Delbos Krampe, Jeanne, Pharmaceutically active oligosaccharide conjugates.
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  946. Belmont, John W.; Fletcher, Frederick A.; Chen, Alice J.; Jurecic, Roland; Tan, Tse-Hua; Zhou, Guisheng, Phosphatases which activate map kinase pathways.
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  947. Belmont,John W.; Fletcher,Frederick A.; Chen,Alice J.; Jurecic,Roland; Tan,Tse Hua; Zhou,Guisheng, Phosphatases which activate map kinase pathways.
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  948. Nagaoka Shoji (Kamakura JPX) Kurumatani Hajimu (Kamakura JPX) Mori Yuichi (Kamakura JPX), Physiologically-active substance fixed to a thin fiber carrier with an alkylene oxide chain.
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  949. Bertozzi, Carolyn; Agarwal, Paresh; Sletten, Ellen M., Pictet-Spengler ligation for protein chemical modification.
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  950. Hunter Robert L. (Tucker GA), Plasma extender.
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  951. Sexton, Daniel J.; Viswanathan, Malini, Plasma kallikrein binding proteins.
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  952. Sexton, Daniel J.; Viswanathan, Malini, Plasma kallikrein binding proteins.
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  953. Shimizu Kimihiro (Yoshikawa JPX) Nakahara Tsuguji (Tokyo JPX) Kinoshita Taketoshi (Koshigaya JPX) Takatsuka Jun (Kawasaki JPX) Igarashi Michiko (Musashino JPX), Plasminogen activator derivatives.
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  954. Shimizu Kimihiro (Yoshikawa-danchi 4-16-102 Yoshikawa-machi ; Kitakatsushika-gun ; Saitama-ken JPX) Nakahara Tsuguji (6-21-6 Megurohonmachi ; Meguro-ku ; Tokyo JPX) Kinoshita Taketoshi (Satsuki-so ; , Plasminogen activator derivatives.
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  955. Fischetti, Vincent A.; Cheng, Qi, Ply-GBS mutant lysins.
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  956. Harris, J. Milton; Kozlowski, Antoni, Poly (ethylene glycol) derivatives with proximal reactive groups.
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  957. Harris, J. Milton; Kozlowski, Antoni, Poly (ethylene glycol) derivatives with proximal reactive groups.
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  958. Bentley Michael D. ; Harris J. Milton, Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines.
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  959. Harris, J. Milton; Kozlowski, Antoni, Poly(ethylene glycol) derivatives with proximal reactive groups.
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  960. Harris, J. Milton; Kozlowski, Antoni, Poly(ethylene glycol) derivatives with proximal reactive groups.
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  961. J. Milton Harris ; Antoni Kozlowski, Poly(ethylene glycol) derivatives with proximal reactive groups.
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  962. J. Milton Harris ; Antoni Kozlowski, Poly(ethylene glycol) derivatives with proximal reactive groups.
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  963. Whitlow, Marc; Shorr, Robert G. L.; Filpula, David R.; Lee, Lihsyng Standford, Polyalkylene oxide-modified single chain polypeptides.
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  964. Whitlow, Marc; Shorr, Robert G. L.; Filpula, David R.; Lee, Lihsyng Standford, Polyalkylene oxide-modified single chain polypeptides.
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  965. Whitlow, Marc; Shorr, Robert G. L.; Filpula, David R.; Lee, Lihsyng Stanford, Polyalkylene oxide-modified single chain polypeptides.
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  966. Whitlow,Marc; Shorr,Robert G. L.; Filpula,David R.; Lee,Lihsyng Standford, Polyalkylene oxide-modified single chain polypeptides.
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  967. Zhao, Hong, Polyalkylene oxides having hindered ester-based biodegradable linkers.
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  968. Lin, KoChung; Pepinsky, R. Blake; Chen, Ling Ling; Hess, Donna M.; Lin, Edward Y.; Petter, Russell C.; Baker, Darren P., Polyalkylene polymer compounds and uses thereof.
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  969. Lin, KoChung; Pepinsky, R. Blake; Chen, Ling Ling; Hess, Donna M.; Lin, Edward Y.; Petter, Russell C.; Baker, Darren P., Polyalkylene polymer compounds and uses thereof.
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  970. Rose, Keith, Polyamide chains of precise length.
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  971. Harris,J. Milton; Kozlowski,Antoni, Polyethylene (glycol) derivatives with proximal reactive groups.
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  972. Harris,J. Milton; Kozlowski,Antoni, Polyethylene(Glycol) derivatives with proximal reactive groups.
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  973. Hakimi John ; Kilian Patricia ; Rosen Perry, Polyethylene-protein conjugates.
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  974. Hakimi John ; Kilian Patricia ; Rosen Perry, Polyethylene-protein conjugates.
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  975. Hakimi John ; Kilian Patricia ; Rosen Perry, Polyethylene-protein conjugates.
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  976. Hakimi John ; Kilian Patricia ; Rosen Perry, Polyethylene-protein conjugates.
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  977. Hakini John (Scarsdale NY) Kilian Patricia (Upper Montclair NJ) Rosen Perry (North Caldwell NJ), Polyethylene-protein conjugates.
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  978. Bossard, Mary J.; Bentley, Michael D.; Zhang, Ping, Polymer Factor VIII moiety conjugates.
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  979. Pepinsky, Blake; Runkel, Laura; Brickelmaier, Margot; Whitty, Adrian; Hochman, Paula, Polymer conjugates of interferon beta-1A and uses.
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  980. Pepinsky,Blake; Runkel,Laura; Brickelmaier,Margot; Whitty,Adrian; Hochman,Paula, Polymer conjugates of interferon beta-1A and uses.
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  981. Pepinsky, Blake; Runkel, Laura; Brickelmaier, Margot; Whitty, Adrian; Hochman, Paula, Polymer conjugates of interferon beta-1a and uses.
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  982. Saifer, Mark G. P.; Martinez, Alexa L.; Williams, L. David; Sherman, Merry R., Polymer conjugates of interferon-beta with enhanced biological potency.
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  983. Sherman,Merry R.; Martinez,Alexa L.; Bhaskaran,Shyam S.; Williams,L. David; Saifer,Mark G. P.; French,John A., Polymer conjugates of proteinases.
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  984. Martinez, Alexa L; Sherman, Merry R; Saifer, Mark G. P.; Williams, L. David, Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof.
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  985. Harris, J. Milton; Kozlowski, Antoni; McManus, Samuel P.; Bentley, Michael D.; Charles, Stephen A., Polymer derivatives having particular atom arrangements.
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  986. Harris, J. Milton; Kozlowski, Antoni, Polymer derivatives with proximal reactive groups.
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  987. Bossard, Mary J.; Stephenson Phillips, Gayle, Polymer factor IX moiety conjugates.
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  988. Bossard, Mary J.; Bentley, Michael D.; Zhang, Ping, Polymer factor VIII moiety conjugates.
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  989. Bentley, Michael David; Roberts, Michael James, Polymer stabilized neuropeptides.
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  990. Bentley, Michael David; Roberts, Michael James, Polymer stabilized neuropeptides.
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  991. Scheiflinger, Friedrich; Turecek, Peter; Siekmann, Jueren, Polymer von Willebrand factor-conjugates.
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  992. Bossard, Mary J.; Stephenson, Gayle, Polymer-factor IX moiety conjugates.
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  993. Bossard, Mary J.; Bentley, Michael D.; Zhang, Ping, Polymer-factor VIII conjugate compositions.
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  994. Bossard, Mary J.; Bentley, Michael D.; Zhang, Ping, Polymer-factor VIII moiety conjugates.
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  995. Bossard, Mary J.; Bentley, Michael D.; Zhang, Ping, Polymer-factor VIII moiety conjugates.
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  996. Bossard, Mary J.; Bentley, Michael D.; Zhang, Ping, Polymer-factor VIII moiety conjugates.
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  997. Bossard, Mary J.; Bentley, Michael D.; Zhang, Ping, Polymer-factor VIII moiety conjugates.
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  998. Bossard,Mary J.; Bentley,Michael D., Polymer-factor VIII moiety conjugates.
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  999. Scheiflinger, Friedrich; Turecek, Peter; Siekmann, Juergen, Polymer-factor VIII-von Willebrand factor-conjugates.
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  1000. Kochendoerfer,Gerd G.; Botti,Paolo; Bradburne,James A.; Chen,Shiah yun; Cressman,Sonya; Hunter,Christie L.; Kent,Stephen B. H.; Low,Donald W.; Wilken,Jill G., Polymer-modified synthetic proteins.
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  1001. Scheiflinger, Friedrich; Turecek, Peter; Siekmann, Juergen, Polymer-von Willebrand factor-conjugates.
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  1002. Scheiflinger, Friedrich; Turecek, Peter; Siekmann, Juergen, Polymer-von Willebrand factor-conjugates.
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  1003. Greenwald Richard B. ; Pendri Annapurna ; Choe Yun H., Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents.
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  1004. Veronese Francesco M. (Padua ITX) Schiavon Oddone (Padua ITX) Caliceti Paolo (Padua ITX) Sartore Luciana (Marano Vic. ITX) Ranucci Elisabetta (Brescia ITX) Ferruti Paolo (Milan ITX), Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces.
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  1005. Veronese Francesco M. (Padua ITX) Schiavon Oddone (Padua ITX) Caliceti Paolo (Padua ITX) Sartore Luciana (Marano Vic. ITX) Ranucci Elisabetta (Brescia ITX) Ferruti Paolo (Milan ITX), Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces.
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  1006. Carra, Ernest; Gerber, Michael; Shi, Bing; Sujino, Keiko; Tran, Duong; Wang, Fang; Evarts, Jerry B., Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one.
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  1007. Carra, Ernest; Gerber, Michael; Shi, Bing; Sujino, Keiko; Tran, Duong; Wang, Fang; Evarts, Jerry B., Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one.
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  1008. Buttar, Suzanne; Carra, Ernest; Ehiwe, Tracy; Tran, Duong; Wang, Fang; Worrall, Christopher; Evarts, Jerry, Polymorphic forms of a hydrochloride salt of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one.
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  1009. Feder,John N.; Nelson,Thomas C.; Chen,Jian; Meegalla,Rupalie; Ramaker,Michael; Cheng,Dong, Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof.
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  1010. Emanuele R. Martin (Alpharetta GA) Hunter Robert L. (Tucker GA) Culbreth Paula H. (Loganville GA), Polyoxypropylene/polyoxyethylene copolmers with improved biological activity.
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  1011. Emanuele R. Martin ; Hunter Robert L. ; Culbreth Paula H., Polyoxypropylene/polyoxyethylene copolmers with improved biological activity.
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  1012. Emanuele R. Martin ; Hunter Robert L. ; Culbreth Paula H., Polyoxypropylene/polyoxyethylene copolymers with improved biological activity.
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  1013. Emanuele R. Martin ; Hunter Robert L. ; Culbreth Paula H., Polyoxypropylene/polyoxyethylene copolymers with improved biological activity.
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  1014. Emanuele, R. Martin; Hunter, Robert L.; Culbreth, Paula H., Polyoxypropylene/polyoxyethylene copolymers with improved biological activity.
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  1015. Emanuele, R. Martin; Hunter, Robert L.; Culbreth, Paula H., Polyoxypropylene/polyoxyethylene copolymers with improved biological activity.
    상세보기
  1016. R. Martin Emanuele ; Robert L. Hunter ; Paula H. Culbreth, Polyoxypropylene/polyoxyethylene copolymers with improved biological activity.
    상세보기
  1017. Fujii, Nobutaka, Polypeptide anti-HIV agent containing the same.
    상세보기
  1018. Olsen Arne Agerlin,DKX ; Hansen Lars Bo,DKX ; Beck Thomas Christian,DKX, Polypeptide with reduced allergenicity.
    상세보기
  1019. Olsen Arne Agerlin,DKX ; Hansen Lars Bo,DKX ; Beck Thomas Christian,DKX, Polypeptide with reduced allergenicity.
    상세보기
  1020. Olsen Arne Agerlin,DKX ; Hansen Lars Bo,DKX ; Beck Thomas Christian,DKX, Polypeptide with reduced respiratory allergenicity.
    상세보기
  1021. Clark, Richard A., Polypeptides and methods of use.
    상세보기
  1022. Deussen, Heinz-Josef; Olsen, Arne Agerlin; Fatum, Tine Muxoll; Roggen, Erwin Ludo, Polypeptides conjugated to copolymers of ethylene oxide and propylene oxide to reduce allergenicity.
    상세보기
  1023. Olsen Arne Agerlin,DKX ; Fatum Tine Muxoll,DKX ; Deussen Heinz Josef,DKX ; Roggen Erwin Ludo,DKX, Polypeptides conjugated with polymers.
    상세보기
  1024. Magruder Judy A. ; Eckenhoff James B. ; Cortese Richard ; Wright Jeremy C. ; Peery John R., Polyurethane-containing delivery systems.
    상세보기
  1025. Mirkin, Chad A.; Giljohann, David A.; Seferos, Dwight S.; Prigodich, Andrew E.; Patel, Pinal C., Polyvalent RNA-nanoparticle compositions.
    상세보기
  1026. Mirkin, Chad A.; Giljohann, David A.; Seferos, Dwight; Prigodich, Andrew E.; Patel, Pinal C., Polyvalent RNA-nanoparticle compositions.
    상세보기
  1027. Gerarda Havenith, Catharina Emanuele; Vink, Tom; Berkel, Patrick Van; Parren, Paul, Potency assays for antibody drug substance binding to an Fc receptor.
    상세보기
  1028. Nho, Kwang; Hyun, Changmin; Lee, Junghun; Pak, Youngkyoung, Preparation method of peg-maleimide derivatives.
    상세보기
  1029. Nitecki Danute E. (Berkeley CA) Katre Nandini (El Cerrito CA) Goodson Robert J. (Albany CA) Aldwin Lois (San Mateo CA), Preparation of a polymer/interleukin-2 conjugate.
    상세보기
  1030. Hazra, Partha; Shivarudraiah, Manjunath Hadavanahalli; Khedkar, Anand; Iyer, Harish; Dave, Nitesh; Krishnan, Gautam; Suryanarayan, Shrikumar, Preparation of insulin conjugates.
    상세보기
  1031. Zalipsky,Samuel, Preparation of macromolecular conjugates by four-component condensation reaction.
    상세보기
  1032. Meyer Damon L. ; Mallett Robert W., Pretargeting methods and compounds.
    상세보기
  1033. Ladner, Robert C.; Ley, Arthur C., Prevention and reduction of blood loss.
    상세보기
  1034. Ladner, Robert C.; Ley, Arthur C., Prevention and reduction of blood loss.
    상세보기
  1035. Ladner, Robert C.; Ley, Arthur C.; Hirani, Shirish; Williams, Anthony, Prevention and reduction of blood loss.
    상세보기
  1036. Ladner, Robert C.; Ley, Arthur C.; Hirani, Shirish; Williams, Anthony, Prevention and reduction of blood loss.
    상세보기
  1037. Ladner, Robert C.; Ley, Arthur C.; Hirani, Shirish; Williams, Anthony, Prevention and reduction of blood loss.
    상세보기
  1038. Ladner, Robert Charles; Ley, Arthur Charles; Hirani, Shirish; Williams, Anthony, Prevention and reduction of blood loss.
    상세보기
  1039. Ladner,Robert C.; Ley,Arthur C.; Hirani,Shirish; Williams,Anthony, Prevention and reduction of blood loss.
    상세보기
  1040. Ladner,Robert C.; Ley,Arthur C.; Hirani,Shirish; Williams,Anthony, Prevention and reduction of blood loss.
    상세보기
  1041. Sabbadini, Roger A., Prevention and treatment of pain using antibodies to sphingosine-1-phosphate.
    상세보기
  1042. Thorn, Karina; Toby, Garabet G.; Mezo, Adam R., Pro-coagulant compounds and methods of use thereof.
    상세보기
  1043. Cristina Delgado GB; Gillian Elizabeth Francis GB; Derek Fisher GB, Process for fractionating polyethylene glycol (PEG) -protein adducts and an adduct of PEG and granulocyt-macrophage colony stimulating factor.
    상세보기
  1044. Delgado Cristina,GBX ; Francis Gillian Elizabeth,GBX ; Fisher Derek,GBX, Process for fractionating polyethylene glycol (PEG)-protein adducts and an adduct of PEG and granulocyte-macrophage colo.
    상세보기
  1045. Bremner, Stacy; Evarts, Jerry; Sujino, Keiko; Tran, Duong; Vizitiu, Dragos, Process for preparing phosphatidylinositol 3-kinase inhibitors and intermediates thereof.
    상세보기
  1046. Faure,Marie Pierre; Ibea,Micheal, Process for the preparation of activated polyethylene glycols.
    상세보기
  1047. Faure,Marie Pierre; Shingel,Kirill, Process for the preparation of activated polyethylene glycols.
    상세보기
  1048. Faure, Marie-Pierre; Shingel, Kirill, Process for the preparation of activated polythylene glycols.
    상세보기
  1049. Dave, Nitesh; Hazra, Partha; Goel, Anuj; Roy, Nita; Khedkar, Anand; Iyer, Harish; Krishnan, Gautam; Manjunath, H. S.; Suryanarayan, Shrikumar; Manikam, Govindasamy; Sachdev, Goldy; Garg, Mayank, Process for the preparation of insulin conjugate IN-105.
    상세보기
  1050. DeFrees, Shawn; Bowe, Caryn, Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography.
    상세보기
  1051. Bremner, Stacy; Evarts, Jerry; Sujino, Keiko; Tran, Duong; Vizitiu, Dragos, Process methods for phosphatidylinositol 3-kinase inhibitors.
    상세보기
  1052. Bremner, Stacy; Evarts, Jerry; Sujino, Keiko; Tran, Duong; Vizitiu, Dragos, Process methods for phosphatidylinositol 3-kinase inhibitors.
    상세보기
  1053. Ehrich, Mathias; Nygren, Anders Olof Herman, Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses.
    상세보기
  1054. Ehrich, Mathias; Nygren, Anders Olof Herman; Jensen, Taylor Jacob, Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses.
    상세보기
  1055. Ehrich, Mathias; Mistro, Guy Del; Deciu, Cosmin; Chen, Yong Qing; McCullough, Ron Michael; Tim, Roger Chan, Processes and kits for identifying aneuploidy.
    상세보기
  1056. Radhakrishnan, Balasingam; Soltero, Richard; Ekwuribe, Nnochiri N., Proinsulin polypeptide-oligomer conjugates.
    상세보기
  1057. Weisgerber, David John; Rubingh, Donn Nelton; Correa, Paul Elliott, Protease conjugates having sterically protected clip sites.
    상세보기
  1058. Rubingh, Donn Nelton; Weisgerber, David John; Correa, Paul Elliott, Protease conjugates having sterically protected epitope regions.
    상세보기
  1059. Nielsen, Peter Kresten; Hubalek, Frantisek; Lautrup-Larsen, Inger; Ludvigsen, Svend; Ribel-Madsen, Ulla; Balschmidt, Per; Nørgaard, Per; Havelund, Svend, Protease resistant insulin analogues.
    상세보기
  1060. Madsen, Peter; Kjeldsen, Thomas B.; Hoeg-Jensen, Thomas; Jakobsen, Palle; Tagmose, Tina Moeller; Kodra, Janos Tibor, Protease stabilized acylated insulin analogues.
    상세보기
  1061. Madsen, Peter; Kjeldsen, Thomas Boerglum; Hoeg-Jensen, Thomas; Jakobsen, Palle; Tagmose, Tina Moeller; Glendorf, Tine; Kodra, Janos Tibor; Garibay, Patrick William; Petersen, Jacob Sten, Protease stabilized acylated insulin analogues.
    상세보기
  1062. Nielsen, Peter Kresten; Hubalek, Frantisek; Lautrup-Larsen, Inger; Balschmidt, Per; Ludvigsen, Svend; Kjeldsen, Thomas Børglum, Protease-stabilized insulin analogues.
    상세보기
  1063. David John Weisgerber ; Donn Nelton Rubingh ; Paul Elliott Correa, Proteases having modified amino acid sequences conjugated to addition moieties.
    상세보기
  1064. Dörwald, Florencio Zaragoza, Protein conjugates and methods for their preparation.
    상세보기
  1065. Suzuki Yosuke,JPX ; Sato Syuji,JPX, Protein or polypeptide, method for producing the same and intermediate compound therefor.
    상세보기
  1066. DeFrees, Shawn; Zopf, David; Bayer, Robert; Hakes, David; Chen, Xi, Protein remodeling methods and proteins/peptides produced by the methods.
    상세보기
  1067. Goto, Masaaki; Tsuda, Eisuke; Mochizuki, Shin'ichi; Yano, Kazuki; Kobayashi, Fumie; Shima, Nobuyuki; Yasuda, Hisataka; Nakagawa, Nobuaki; Morinaga, Tomonori; Ueda, Masatsugu; Higashio, Kanji, Proteins and methods for producing the proteins.
    상세보기
  1068. Goto,Masaaki; Tsuda,Eisuke; Mochizuki,Shin'ichi; Yano,Kazuki; Kobayashi,Fumie; Shima,Nobuyuki; Yasuda,Hisataka; Nakagawa,Nobuaki; Morinaga,Tomonori; Ueda,Masatsugu; Higashio,Kanji, Proteins and methods for producing the proteins.
    상세보기
  1069. Goto,Masaaki; Tsuda,Eisuke; Mochizuki,Shin'ichi; Yano,Kazuki; Kobayashi,Fumie; Shima,Nobuyuki; Yasuda,Hisataka; Nakagawa,Nobuaki; Morinaga,Tomonori; Ueda,Masatsugu; Higashio,Kanji, Proteins and methods for producing the proteins.
    상세보기
  1070. Patton, John S.; Kuo, Mei-Chang; Harris, J. Milton; Leach, Chester; Perkins, Kimberly; Bueche, Blaine, Pulmonary administration of chemically modified insulin.
    상세보기
  1071. Niven, Ralph; Pitt, Colin G, Pulmonary administration of granulocyte colony stimulating factor.
    상세보기
  1072. Fischer, Meir; Harosh, Eliyahu, Purification of proteins with cationic surfactant.
    상세보기
  1073. Nygren, Anders, Quantification of a minority nucleic acid species.
    상세보기
  1074. Nygren, Anders, Quantification of a minority nucleic acid species.
    상세보기
  1075. Nygren, Anders, Quantification of a minority nucleic acid species.
    상세보기
  1076. Fowler, Kerry W.; Huang, Danwen; Kesicki, Edward A.; Ooi, Hua Chee; Oliver, Amy; Ruan, Fuqiang; Treiberg, Jennifer, Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta.
    상세보기
  1077. Fowler, Kerry W.; Huang, Danwen; Kesicki, Edward A.; Ooi, Hua Chee; Oliver, Amy; Ruan, Fuqiang; Treiberg, Jennifer; Puri, Kamal Deep, Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta.
    상세보기
  1078. Fowler, Kerry W.; Huang, Danwen; Kesicki, Edward A.; Ooi, Hua Chee; Oliver, Amy; Ruan, Fuqiang; Treiberg, Jennifer; Puri, Kamal Deep, Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta.
    상세보기
  1079. Anderson, Dirk M, RANK ligand polypeptides.
    상세보기
  1080. Soliman, Tarik; Hales, Laura M.; Hall, Daniel B.; Sard, Howard P.; Hegde, Vishnumurthy, RNAi vitamin D conjugates.
    상세보기
  1081. Moore, Gregory L.; Desjarlais, John; Bernett, Matthew, Rapid clearance of antigen complexes using novel antibodies.
    상세보기
  1082. Zhao, Hong; Martinez, Anthony J., Reacting polyalkylene oxide with base, tertiary alkyl haloacetate, then acid to prepare polyalkylene oxide carboxylic acid.
    상세보기
  1083. Halenbeck, Robert F.; Kriegler, Michael; Tuttleman, Jan; Perez, Carl; Jewell, David A.; Koths, Kirston E., Recombinant PR-3 and assays employing the same.
    상세보기
  1084. Halenbeck, Robert F.; Kriegler, Michael; Perez, Carl; Jewell, David A.; Koths, Kirston E., Recombinant PR-3 and compositions thereof.
    상세보기
  1085. Yim, Kalvin; Danso, Steven; Hausknecht, Edward, Recombinant butyrylcholinesterases and truncates thereof.
    상세보기
  1086. Yim, Kalvin; Danso, Steven; Hausknecht, Edward, Recombinant butyrylcholinesterases and truncates thereof.
    상세보기
  1087. Wang, Haitao; Mao, Chungsheng; Li, Jizhi; Xu, Jing; Zhang, Rui; Wang, Ling; Du, Yong; Liu, Longbin, Recombinant human interferon-like proteins.
    상세보기
  1088. Wang, Haitao; Mao, Chunsheng; Li, Jizhi; Wang, Ling; Du, Yong; Liu, Longbin; Xu, Jing; Zhang, Rui, Recombinant human interferon-like proteins.
    상세보기
  1089. Wang, Haitao; Mao, Chunsheng; Li, Jizhi; Wang, Ling; Du, Yong; Liu, Longbin; Xu, Jing; Zhang, Rui, Recombinant human interferon-like proteins.
    상세보기
  1090. Wang, Haitao; Mao, Chunsheng; Li, Jizhi; Xu, Jing; Zhang, Rui; Wang, Ling; Du, Yong; Liu, Longbin, Recombinant human interferon-like proteins.
    상세보기
  1091. Wang, Haitao; Mao, Chunsheng; Li, Jizhi; Xu, Jing; Zhang, Rui; Wang, Ling; Du, Yong; Liu, Longbin, Recombinant human interferon-like proteins.
    상세보기
  1092. Wang, Haitao; Mao, Chunsheng; Li, Jizhi; Wang, Ling; Du, Yong; Liu, Longbin; Xu, Jing; Zhang, Rui, Recombinant human interferon-like proteins and method of treatment using them.
    상세보기
  1093. Fisher, Timothy C.; Armstrong, Jonathan K., Red blood cells covalently bound with polymers.
    상세보기
  1094. Fisher Timothy C. ; Armstrong Jonathan K., Red blood cells covalently bound with two different polyethylene glycol derivatives.
    상세보기
  1095. Wilmen, Andreas; Haupts, Ulrich; Freiberg, Christoph; Trautwein, Mark; Linden, Lars; Leineweber, Kirsten; Tinel, Hanna, Relaxin fusion polypeptides and uses thereof.
    상세보기
  1096. Samuel Zalipsky, Releasable linkage and compositions containing same.
    상세보기
  1097. Zalipsky, Samuel, Releasable linkage and compositions containing same.
    상세보기
  1098. Zalipsky, Samuel, Releasable linkage and compositions containing same.
    상세보기
  1099. Zalipsky, Samuel, Releasable linkage and compositions containing same.
    상세보기
  1100. Zalipsky, Samuel; Kiwan, Radwan, Releasable linkage and compositions containing same.
    상세보기
  1101. Zalipsky,Samuel, Releasable linkage and compositions containing same.
    상세보기
  1102. Zalipsky,Samuel; Kiwan,Radwan, Releasable linkage and compositions containing same.
    상세보기
  1103. Zhao, Hong; Greenwald, Richard B.; Adler, legal representative, Susan L., Releasable polymeric conjugates based on aliphatic biodegradable linkers.
    상세보기
  1104. Zhao, Hong; Greenwald, Richard B.; Pendri, Annapurna, Releasable polymeric conjugates based on aliphatic biodegradable linkers.
    상세보기
  1105. Zhao,Hong; Greenwald,Richard B., Releasable polymeric conjugates based on aliphatic biodegradable linkers.
    상세보기
  1106. Zhao,Hong; Greenwald,Richard B.; Pendri,Annapurna, Releasable polymeric conjugates based on aliphatic biodegradable linkers.
    상세보기
  1107. Zhao,Hong; Adler, legal representative,Susan; Greenwald,Richard B., Releasable polymeric conjugates based on biodegradable linkers.
    상세보기
  1108. DeFrees,Shawn; Zopf,David A.; Bayer,Robert J.; Hakes,David James; Bowe,Caryn; Chen,Xi, Remodeling and glycoconjugation of peptides.
    상세보기
  1109. DeFrees,Shawn; Zopf,David A.; Bowe,Caryn, Remodeling and glycoconjugation of peptides.
    상세보기
  1110. DeFrees,Shawn; Zopf,David A.; Bowe,Caryn, Remodeling and glycoconjugation of peptides.
    상세보기
  1111. DeFrees, Shawn, Remodeling and glycopegylation of fibroblast growth factor (FGF).
    상세보기
  1112. Rozema,David B.; Wakefield,Darren; Wolff,Jon A.; Ekena,Kirk; Hagstrom,James E., Reversible modification of amine-containing compounds.
    상세보기
  1113. Sebti, Said M.; Hamilton, Andrew D., Rock inhibitors and uses thereof.
    상세보기
  1114. French, Dorothy; Ashkenazi, Avi J.; Stephan, Jean-Philippe F.; Desnoyers, Luc, Screening method.
    상세보기
  1115. McManus, Samuel P.; Kozlowski, Antoni, Segmented degradable polymers and conjugates made therefrom.
    상세보기
  1116. McManus, Samuel P.; Kozlowski, Antoni, Segmented degradable polymers and conjugates made therefrom.
    상세보기
  1117. Zundel, Magali A.; Peschke, Bernd; Dörwald, Florencio Zaragoza; Fiil, Niels Peter; Johansen, Nils Langeland; Stennicke, Henning Ralf, Selectively conjugated peptides and methods of making the same.
    상세보기
  1118. Rubingh, Donn Nelton; Sikorski, Elizabeth Ellen; Correa, Paul Elliott, Serine protease variants having amino acid deletions and substitutions.
    상세보기
  1119. Rubingh, Donn Nelton; Sikorski, Elizabeth Ellen; Correa, Paul Elliott, Serine protease variants having amino acid substitutions.
    상세보기
  1120. Lapidot, Tsvee; Kalinkovich, Alexander; Fridkin, Matityahu, Short beta-defensin-derived peptides.
    상세보기
  1121. Lapidot, Tsvee; Kalinkovich, Alexander; Fridkin, Matityahu, Short beta-defensin-derived peptides.
    상세보기
  1122. DeFrees,Shawn; Zopf,David; Bayer,Robert; Bowe,Caryn; Hakes,David; Chen,Xi, Sialic acid nucleotide sugars.
    상세보기
  1123. Thompson, Peter Armstrong; Ledbetter, Jeffrey A.; Hayden-Ledbetter, Martha Susan; Grosmaire, Laura Sue; Bader, Robert; Brady, William, Single chain multivalent binding proteins with effector function.
    상세보기
  1124. Filpula David ; Wang Maoliang ; Shorr Robert ; Whitlow Marc ; Lee Lihsyng S., Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof.
    상세보기
  1125. Filpula, David; Wang, Maoliang; Shorr, Robert; Whitlow, Marc; Lee, Lihsyng S., Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof.
    상세보기
  1126. Filpula, David; Wang, Maoliang; Shorr, Robert; Whitlow, Marc; Lee, Lihsyng S., Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof.
    상세보기
  1127. Pettit, Dean K., Site protected protein modification.
    상세보기
  1128. Dean K. Pettit, Site specific protein modification.
    상세보기
  1129. Dean K. Pettit, Site specific protein modification.
    상세보기
  1130. Pettit,Dean K., Site specific protein modification.
    상세보기
  1131. Kim, Seung Su; Lim, Se Young; Jung, Sung Youb; Kwon, Se Chang, Site-specific GLP-2 conjugate using an immunoglobulin fragment.
    상세보기
  1132. Usera, Aimee; Robinson, Zachary; Cobb, Jennifer, Site-specific chemoenzymatic protein modifications.
    상세보기
  1133. Hinds, Kenneth; Lewis, Danny; Schmidt, Paul; Campbell, Kathleen M., Site-specific insulin-polymer conjugates.
    상세보기
  1134. Tonon, Giancarlo; Orsini, Gaetano; Sergi, Mauro; Schrepfer, Rodolfo; Esposito, Pierandrea, Site-specific monoconjugated insulinotropic GLP-1 peptides.
    상세보기
  1135. Katre Nandini (El Cerrito CA) Knauf Michael J. (Oakland CA), Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation.
    상세보기
  1136. Koths Kirston ; Taylor Eric, Soluble extracellular domain of human M-CSF receptor.
    상세보기
  1137. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
    상세보기
  1138. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
    상세보기
  1139. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
    상세보기
  1140. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
    상세보기
  1141. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
    상세보기
  1142. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
    상세보기
  1143. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
    상세보기
  1144. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
    상세보기
  1145. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
    상세보기
  1146. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
    상세보기
  1147. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
    상세보기
  1148. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
    상세보기
  1149. Bookbinder, Louis H.; Kundu, Anirbau; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
    상세보기
  1150. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
    상세보기
  1151. Harris, J. Milton, Soluble, degradable poly (ethylene glycol) derivatives for controllable release of bound molecules into solution.
    상세보기
  1152. Harris, J. Milton, Soluble, degradable poly (ethylene glycol) derivatives for controllable release of bound molecules into solution.
    상세보기
  1153. Harris J. Milton, Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution.
    상세보기
  1154. Harris, J. Milton, Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution.
    상세보기
  1155. Harris, J. Milton, Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution.
    상세보기
  1156. Harris, J. Milton, Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution.
    상세보기
  1157. Holmes, Christopher P.; Tumelty, David; Yin, Qun, Spacer moiety for poly(ethylene glycol) modified peptide based compounds.
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  1158. Daley Michael Joseph ; Buckwalter Brian Lee ; Cady Susan Mancini ; Shieh Hong-Ming ; Bohlen Peter ; Seddon Andrew P., Stabilization of fibroblast growth factors by modification of cysteine residues.
    상세보기
  1159. Hamilton ; Jr. Edwin J. (Terre Haute IN) Burleigh Bruce D. (Mundelein IL), Stabilization of growth hormones.
    상세보기
  1160. Daley Michael Joseph ; Buckwalter Brian Lee ; Cady Susan Mancini ; Shieh Hong-Ming ; Bohlen Peter ; Seddon Andrew P., Stabilization of somatotropins and other proteins by modification of cysteine residues.
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  1161. Schnieders, Julia; Usener, Dirk; Ruggeberg, Sabrina; Youssef, Ahmed; Kirsch, Martina; Hagendorf, Annika, Stable IgG4 based binding agent formulations.
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  1171. Frost, Gregory I.; Bilinsky, Igor; Vaughn, Daniel; Sugarman, Barry, Super fast-acting insulin compositions.
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  1179. Peled, Amnon; Begin, Michal; Beider, Katia; Abraham, Michal, T-140 peptide analogs having CXCR4 super-agonist activity for cancer therapy.
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  1230. Adams, Camellia W.; Ashkenazi, Avi J.; Chuntharapai, Anan; Kim, Kyung Jin, Treatment of cancer using anti-Apo-2 antibodies.
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  1232. Lehmann,Paul; Roeddiger,Ralf; Walter Matsui,Ruth, Treatment of disturbances of iron distribution.
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  1234. Ulrich, Roger G., Treatment of liver disorders with PI3K inhibitors.
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  1237. Wei, Guangwen; Guo, Rongbing; Zhang, Renhuai, Treatment of tumors with recombinant interferon alpha.
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  1240. Smith, Alan E.; O'Riordan, Catherine R.; Francis, Gillian E.; Parkes, Vincent; Delgado, Christina, Tresyl-monomethoxypolyethylene glycol-modified viruses having viral infectivity.
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  1241. Greenwald Richard B. ; Choe Yun H., Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents.
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  1251. Bossard, Mary J.; Bentley, Michael D.; Zhang, Ping, Unit dosage forms of pharmaceutical compositions comprising a polymer-factor VIII polypeptide conjugate.
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  1253. Lucas, John; Briggs, Kristen, Use of adipsin/complement factor D in the treatment of metabolic related disorders.
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  1255. Shami Ezekiel Y. (Ontario CAX) Rothstein Aser (Ontario CAX) Ramjeesingh Mohabir (Ontario CAX), Use of antibody/antigen interactions to protect biologically active proteins and peptides.
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  1256. Bennett,D. Clark; Cauchon,Elizabeth; Fink,Dominique; Grouix,Brigette; Hsia,Ariane; Danagher,Pamela; Zimmermann,Joseph F., Use of heparinases to decrease inflammatory response.
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  1257. Rosendahl, Mary S.; Mantripragada, Sankaram B.; Gomez, Eliana B., Use of hydrophobic organic acids to increase hydrophobicity of proteins and protein conjugates.
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  1258. Arnould, Sylvain; Bruneau, Sylvia; Cabaniols, Jean-Pierre; Chames, Patrick; Choulika, Andre; Duchateau, Philippe; Epinat, Jean-Charles; Gouble, Agnes; Lacroix, Emmanuel; Paques, Frederic; Perez-Michaut, Christophe; Smith, Julianne; Sourdive, David, Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof.
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  1265. Belouski, Edward John; Ellison, Murielle Marie; Hamburger, Agnes Eva; Hecht, Randy Ira; Li, Yue-Sheng; Michaels, Mark Leo; Sun, Jeonghoon; Xu, Jing, Uses of FGF21 polypeptides comprising two or more mutations.
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  1266. Chen, Tingchao; Zhao, Yi; Anderson, W. French, Uses of IL-12 in hematopoiesis.
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  1269. Matthews William ; Austin Timothy W., Uses of Wnt polypeptides.
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  1284. Thomason, Arlen; Liu, Benxian, Vectors and recombinant host cells comprising nucleic acid molecules encoding Fibroblast Growth Factor-like polypeptides.
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  1285. Soliman, Tarik; Hales, Laura M.; Sard, Howard P.; Amere, Mukkanti, Vitamin D-ghrelin conjugates.
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  1286. Bossard, Mary J.; Stephenson, Gayle; Fang, Zhihao; Zappe, Harold; Mitchell, Stacy; Zhang, Ping; Scheiflinger, Friedrich; Turecek, Peter; Siekmann, Juergen; Varadi, Katalin; Gritsch, Herbert, Von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage.
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  1288. Greenwald Richard B. ; Martinez Anthony J., Water-soluble non-antigenic polymer linkable to biologically active material.
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  1289. Miranda, Leslie Philip; Kent, Stephen B. H., Water-soluble thioester and selenoester compounds and methods for making and using the same.
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  1290. Wild Hanno,DEX ; Hanko Rudolf,DEX ; Dorschug Michael,DEX ; Horlein Hans-Dietrich,DEX ; Beunink Jurgen,DEX ; Apeler Heiner,DEX ; Wehlmann Hermann,DEX ; Sebald Walter,DEX, hIL-4 mutant proteins used as antagonists or partial agonists of human interleukin 4.
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  1291. Bossard, Mary J.; Stephenson, Gayle; Fang, Zhihao; Zappe, Harold; Mitchell, Stacy; Zhang, Ping; Scheiflinger, Friedrich; Turecek, Peter; Siekmann, Juergen; Varadi, Katalin; Gritsch, Herbert, von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage.
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