초록 ▼

An internally smooth disposable column, of various sizes up to 800 ml. internal volume, made of biocompatible polymer is filled with particulate absorbent, e.g. carbon coated with polyHEMA, between support means located as close as practicable to inlet and outlet. L/D ratio is usually 1.5:1-5:1. Var

An internally smooth disposable column, of various sizes up to 800 ml. internal volume, made of biocompatible polymer is filled with particulate absorbent, e.g. carbon coated with polyHEMA, between support means located as close as practicable to inlet and outlet. L/D ratio is usually 1.5:1-5:1. Various shapes e.g. double frustoconical or trochoid of revolution are proposed for the column, which is preferably symmetrical to facilitate moulding of identical column halves; these shapes usually converge to meet a funnel-shaped connecting piece at inlet and outlet.

대표청구항 ▼

Disposable haemoperfusion equipment comprising: (A) a column, (i) formed in biocompatible synthetic polymer material, (ii) having a smooth internal surface, (iii) enclosing perforate internal support means towards each end of said column (iv) diminishing in diameter from a maximum diameter intermedi

Disposable haemoperfusion equipment comprising: (A) a column, (i) formed in biocompatible synthetic polymer material, (ii) having a smooth internal surface, (iii) enclosing perforate internal support means towards each end of said column (iv) diminishing in diameter from a maximum diameter intermediate said ends, and then (v) converging smoothly at each end of said column to an inlet port and an outlet port respectively, each such port defining a minimal dead space between itself and the nearer support means, (vi) said column having a length to maximum diameter ratio of 1.5:1 to 5:1 and an internal volume of 50 to 800 ml., and (vii) said column being formed as two identical halves located end to end, each half possessing a first frusto-conical tapering portion having an included angle of from 10°to 30°, and a second frusto-conical tapering portion, integral with said first portion, but of an included angle of from 50°to 70°, tapering to a liquid flow connection at each end of said column; (B) a body of absorbtive particulate material, (i) substantially filling the column and held between the support means so that the particles do not move relatively in use, and (ii) consisting of particles having a smooth biocompatible surface; and (C) a biocompatible liquid charge filling the column, chosen from the group of degassed isotonic saline and plasma extender. Disposable haemoperfusion equipment, comprising: (A) a column, the internal shape of which is that of a trochoid of revolution, (i) formed in biocompatible synthetic polymer material, (ii) having a smooth internal surface, (iii) enclosing perforate internal support means towards each end of the column, (iv) diminishing in diameter from a maximum diameter intermediate said ends, and then (v) converging smoothly at each end of said column to an inlet port and an outlet port respectively, each such port defining a minimal dead space between itself and the nearer support means, (vi) said column having a length to maximum diameter ratio of 1.5:1 to 5:1 and an internal volume of 50 to 800 ml; (B) a body of absorbtive particulate material, (i) substantially filling the column and held between the support means so that the particles do not move relatively in use, and (ii) consisting of particles having a smooth biocompatible surface; and (C) a biocompatible liquid charge filling the column, chosen from the group of degassed isotonic saline and plasma extender.