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4-Hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxides and salts thereof 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07D-417/12
  • A61K-031/38
출원번호 US-0966963 (1978-12-06)
우선권정보 DE-2756113 (1977-12-16)
발명자 / 주소
  • Trummlitz Gnter (Biberach an der Riss DEX) Engel Wolfhard (Biberach an der Riss DEX) Seeger Ernst (Biberach an der Riss DEX) Engelhardt Gnther (Biberach an der Riss DEX)
출원인 / 주소
  • Boehringer Ingelheim GmbH (DEX 03)
인용정보 피인용 횟수 : 40  인용 특허 : 2

초록 ▼

Compounds of the formula [Figure] wherein R1 is hydrogen, methyl or ethyl; R2 is methyl, ethyl or n-propyl; and Y is hydrogen, methyl, methoxy, fluorine or chlorine; and non-toxic, pharmacologically acceptable salts thereof formed with an inorganic or organic base. The compounds as well as their sal

대표청구항 ▼

A compound of the formula [Figure] wherein R1 is hydrogen, methyl or ethyl; R2 is methyl, ethyl or n-propyl; and Y is hydrogen, methyl, methoxy, fluorine or chlorine or a non-toxic, pharmacologically acceptable salt thereof formed with an inorganic or organic base. The method of counteracting inflam

이 특허에 인용된 특허 (2)

  1. Zinnes ; Harold ; Lindo ; Neil A. ; Shavel ; Jr. ; John, 2-[(N-2-pyridylcarbamoyl)methyl]saccharin.
    상세보기
  2. Hammen ; Philip D., 3,4-Dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide.
    상세보기

이 특허를 인용한 특허 (40)

  1. Wasley Jan W. F. (Chatham NJ), 2,1-benzothiazepine-2,2-dioxide-5-carboxylic acid derivatives.
    상세보기
  2. Trummlitz Gnter (Warthausen DEX) Engel Wolfhard (Biberach DEX) Seeger Ernst (Biberach DEX) Haarmann Walter (Biberach DEX), Antithrombotic N-(6-chloro-pyrazin-2-yl)-4-Hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide derivatives, compositi.
    상세보기
  3. McKearn, John P; Masferrer, Jaime L; Milas, Luka, Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia.
    상세보기
  4. Housey, Gerard M., Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators.
    상세보기
  5. Housey, Gerard M.; Balash, Monica E., Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators.
    상세보기
  6. Housey, Gerard M.; Balash, Monica E., Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators.
    상세보기
  7. Folger, Martin A.; Crowley, Samuel C.; Wilson, Amy J., Containers for compositions comprising meloxicam.
    상세보기
  8. Folger, Martin A.; Crowley, Samuel; Wilson, Amy, Containers for compositions comprising meloxicam.
    상세보기
  9. Lombardino Joseph G. (Niantic CT), Crystalline benzothiazine dioxide salts.
    상세보기
  10. Coppi, Laura; Sanmarti, Marti Bartra; Clavo, Montserrat Closa, Crystalline forms of meloxicam and processes for their preparation and interconversion.
    상세보기
  11. Burns, David Allen; Neal, Gregory Edward, Fast disintegrating compositions of meloxicam.
    상세보기
  12. Henke, Stefan; Kruss, Bernd; Hassel, Bernhard; Kroff, Hans-Juergen; Folger, Martin A.; Daneck, Klaus; Prox, Axel, Highly concentrated stable meloxicam solutions.
    상세보기
  13. Henke, Stefan; Kruss, Bernd; Hassel, Bernhard; Kroff, Hans-Jurgen; Folger, Martin A.; Daneck, Klaus; Prox, Axel, Highly concentrated stable meloxicam solutions.
    상세보기
  14. Folger, Martin A.; Henke, Stefan; Hassel, Bernhard; Zierenberg, Bernd, Highly concentrated stable meloxicam solutions for needleless injection.
    상세보기
  15. Folger, Martin A.; Henke, Stefan; Hassel, Bernhard; Zierenberg, Bernd, Highly concentrated stable meloxicam solutions for needleless injection.
    상세보기
  16. Hanna, Mazen; Shan, Ning; Cheney, Miranda L.; Weyna, David R., In vivo studies of crystalline forms of meloxicam.
    상세보기
  17. Masferrer,Jaime; Doshi,Parul; Cherrington,Julie, Indolinone protein kinase inhibitors and cyclooxygenase inhibitors for use in combination therapy for the treatment of cancer.
    상세보기
  18. Chern, Rey T.; Zingerman, Joel R., Liquid polymeric compositions for controlled release of bioactive substances.
    상세보기
  19. Folger, Martin A.; Lehner, Stefan; Schmitt, Horst, Low concentration meloxicam tablets.
    상세보기
  20. Folger, Martin A.; Lehner, Stefan; Schmitt, Horst, Low concentration meloxicam tablets.
    상세보기
  21. Bock, Thomas; Saegmueller, Paul; Sieger, Peter; Tuerck, Dietrich, Meloxicam for oral administration.
    상세보기
  22. Saxena, Uday; Pillarisetti, Sivaram; Khanna, Ish, Methods for the treatment of diabetes-associated dyslipdemia.
    상세보기
  23. Cooper, Eugene R.; Ryde, Tuula; Pruitt, John; Kline, Laura, Nanoparticulate meloxicam formulations.
    상세보기
  24. Gebhardt Uwe (Waldkirch DEX) Augart Helmut (Waldkirch DEX) Knecht Adolf (Freiburg DEX), Pharmaceutical compositions containing oxicam derivatives and process for their preparation.
    상세보기
  25. Gant, Thomas G.; Shahbaz, Manouchehr M., Phenylacetic acid inhibitors of cyclooxygenase.
    상세보기
  26. Mezei, Tibor; Simig, Gyula; Molnár, Enikó ; Lukács, Gyula; Porcs-Makkay, Márta; Volk, Balázs; Hofmanné Fekete, Valéria; Nagy, Kálmán; Mesterházy, Norbert; Krasznai, György; Vereczkeyné Donáth, Györgyi; Körtvélyessy, Gyuláné ; Pécsi, Éva, Process for preparation of high-purity meloxicam and meloxicam potassium salt.
    상세보기
  27. McElroy, Liam; Cromie, Lillian; Garret, Mark, Process for the purification of meloxicam.
    상세보기
  28. Vigano', Enrico; Landonio, Ernesto, Process for the purification of meloxicam.
    상세보기
  29. Fries Walter F. (Illertissen DEX), Stabilized injectable solutions of piroxicam.
    상세보기
  30. Blakely, William; Reynolds, Louise; Cromie, Lillian, Stable aqueous suspension.
    상세보기
  31. Guo, Zongru; Cheng, Guifang; Chu, Fengming; Hu, Wen Hui; Xu, Zhi Bin; Bai, Ai Ping, Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof.
    상세보기
  32. Housey, Gerard M., Therameutin modulators.
    상세보기
  33. Housey, Gerard M., Theramutein modulators.
    상세보기
  34. Housey, Gerard M., Theramutein modulators.
    상세보기
  35. Bryans,Justin S.; Johnson,Patrick S.; Ryckmans,Thomas; Stobie,Alan, Triazole derivatives which inhibit vasopressin antagonistic activity.
    상세보기
  36. Johnston, Laura, Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats.
    상세보기
  37. Amedeo Leonardi IT; Rodolfo Testa IT; Luciano Guarneri IT, Use of selective COX-2 inhibitors for the treatment of urinary incontinence.
    상세보기
  38. Lombardino Joseph G. (Niantic CT), Water-soluble benzothiazine dioxide salts.
    상세보기
  39. Henke, Stefan; Folger, Martin A.; Lehmann, Jens; Keilhofer, Diana C.; Kroff, Hans-Juergen; Herz, Nina, Water-soluble meloxicam granules.
    상세보기
  40. Henke, Stefan; Folger, Martin Andreas; Schmalz, Jens; Keilhofer, Diana Christine; Kroff, Hans-Juergen; Herz, Nina, Water-soluble meloxicam granules.
    상세보기

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