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특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Device for dispensing drug by combined diffusional and osmotic operations

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61M-007/00   
미국특허분류(USC) 128/260
출원번호 US-0011121 (1979-02-12)
발명자 / 주소
  • Theeuwes Felix (Los Altos CA)
출원인 / 주소
  • Alza Corporation (Palo Alto CA 02)
인용정보 피인용 횟수 : 109  인용 특허 : 6
초록
▼

A device is disclosed for delivering an agent to an environment of use at a substantially constant rate over time. The device comprises a wall formed of a microporous material surrounding a compartment housing the agent and a thermodynamic member. The member comprises a film formed of an expandable, semipermeable material surrounding a means for expanding the member. The member can occupy any space-position in the compartment, and it also can be in contact with the wall. In operation, when the device is in the environment, agent is delivered from the dev...

대표
청구항
▼

A device for the controlled delivery of a beneficial agent to an environment of use, said device comprising: (a) a microporous wall having a plurality of micropaths through the wall, said microporous wall surrounding and defining: (b) a compartment; (c) a beneficial agent in the compartment; and, (d) an expandable member in the compartment, said member comprising a flexible, semipermeable film surrounding an osmotically effective solute, a gas generating couple, or a swellable polymer; and, (e) wherein, when the device is in operation in the environment ...

인용문헌 (6)

  1. Chandrasekaran Santosh Kumar (Palo Alto CA) Urquhart John (Palo Alto CA) Shaw Jane Elizabeth (Atherton CA), Method and therapeutic system for providing chemotherapy transdermally.
  2. Zaffaroni Alejandro (Atherton CA), Microporous drug delivery device.
  3. Theeuwes ; Felix, Osmotic system for delivering selected beneficial agents having varying degrees of solubility.
  4. Theeuwes ; Felix, Osmotic system for the controlled and delivery of agent over time.
  5. Theeuwes ; Felix, Osmotic system with means for improving delivery kinetics of system.
  6. Wong ; Patrick S. L. ; Smith ; Kelly L. ; Michaels ; Alan S., Therapeutic systems made from certain segmented copolyesters.

이 특허를 인용한 특허 (109)

  1. Eckenhoff James B. (Los Altos CA) Theeuwes Felix (Los Altos CA) Deters Joseph C. (Los Altos CA), Agent dispenser comprising a semipermeable wall surrounding single-piece or two-piece container.
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  44. Guittard George V. (Cupertino CA) Wong Patrick S. L. (Hayward CA) Theeuwes Felix (Los Altos CA) Cortese Richard (Cupertino CA), Dosage form for delivering diltiazem.
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  46. Magruder Paul R. (Palo Alto CA) Wong Patrick S. L. (Hayward CA) Theeuwes Felix (Los Altos CA) Guittard George V. (Cupertino CA), Dosage form for lessening irritation of mocusa.
  47. Ayer Atul D. (Mountain View CA) Wong Patrick S. L. (Hayward CA), Dosage form with means for governing rate of gas formation.
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  52. Maget Henri J. R. (La Jolla CA), Electrochemically driven drug dispenser.
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  56. Magruder Paul R. (Palo Alto CA) Wong Patrick S. (Hayward CA) Theeuwes Felix (Los Altos CA) Guittard George V. (Cupertino CA), Hydrogel formulation for administering non-steroidal drugs.
  57. Lee, Heejin; Duc, Hong Linh Ho; Sansone, Matthew, Implantable device for controlled dissolution and diffusion of low solubility drug.
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