초록 ▼

A process for immobilizing a biological material which can be a protein, a coenzyme having at least one primary or secondary amino group per molecule, an admixture of said coenzyme and an enzyme which is mediated by said coenzyme, or an antibiotic having at least one primary or secondary amino group

A process for immobilizing a biological material which can be a protein, a coenzyme having at least one primary or secondary amino group per molecule, an admixture of said coenzyme and an enzyme which is mediated by said coenzyme, or an antibiotic having at least one primary or secondary amino group per molecule, wherein the biological material is contacted with an excess of an isocyanate-capped liquid polyurethane prepolymer in the absence of water, and the resulting mixture is cured by contacting it with a curing agent to cure the prepolymer and to immobilize the biological material. The resulting mixture can be cured under foam-forming conditions or under nonfoam-forming conditions. The resulting mixture can be formed into a predetermined shape before or during curing or coated onto a surface before or during curing.

대표청구항 ▼

A process for immobilizing a biological material selected from the group consisting of: (a) a protein; (b) a coenzyme having at least one primary or secondary amino group per molecule; (c) an admixture of said coenzyme and an enzyme; and (d) an antibiotic having at least one primary or secondary ami

A process for immobilizing a biological material selected from the group consisting of: (a) a protein; (b) a coenzyme having at least one primary or secondary amino group per molecule; (c) an admixture of said coenzyme and an enzyme; and (d) an antibiotic having at least one primary or secondary amino group per molecule, the process comprising: A. contacting the group member and an excess of an isocyanate-capped liquid polyurethane prepolymer in the absence of water to form a resulting mixture where said prepolymer is the reaction product of a polyether polyol with sufficient polyisocyanate to provide at least two free NCO groups per molecule of the prepolymer; B. shaping the resulting mixture; and C. curing the shaped resulting mixture by contacting it with a curing agent to form a cured shaped article comprising the immobilized biological material.