초록 ▼

Stabilized carrier-bound protein is prepared by reacting a protein in aqueous solution with a mercapto group free, water insoluble carrier which contains binding groups which are reactive with the said protein and reacting the resultant protein-containing mercapto group-free carrier with hydrogen su

Stabilized carrier-bound protein is prepared by reacting a protein in aqueous solution with a mercapto group free, water insoluble carrier which contains binding groups which are reactive with the said protein and reacting the resultant protein-containing mercapto group-free carrier with hydrogen sulfide or with a compound having a molecular weight of less than 5000, and which contains at least two mercapto groups, or at least one mercapto group and at least one hydroxy- group or primary or secondary amino group.

대표청구항 ▼

A method for the preparation of a stabilized carrier-bound protein which comprises: reacting a protein in an aqueous solution with a portion of the oxirane groups of an oxirane group-containing water insoluble carrier which contains no mercapto groups, to form a protein-containing complex; reacting

A method for the preparation of a stabilized carrier-bound protein which comprises: reacting a protein in an aqueous solution with a portion of the oxirane groups of an oxirane group-containing water insoluble carrier which contains no mercapto groups, to form a protein-containing complex; reacting said protein-containing complex with hydrogen sulfide or a compound having a molecular weight less than 5000 which contains at least two mercapto groups; thereby attaching to the remaining oxirane groups of said carrier at least 0.3% by weight of free mercapto groups with respect to the moist weight of the end product.