초록 ▼

An intravaginal contraceptive system for the pre-programmed, unattended delivery of an antifertility steroid is disclosed. The system comprises (a) an antifertility steroid, (b) a delivery module comprising a reservoir for storing the steroid in an amount for execution of the program, a rate control

An intravaginal contraceptive system for the pre-programmed, unattended delivery of an antifertility steroid is disclosed. The system comprises (a) an antifertility steroid, (b) a delivery module comprising a reservoir for storing the steroid in an amount for execution of the program, a rate controller which maintains the rate of steroid delivered in a contraceptive effective amount throughout the life of the system, an energy source for transferring steroid from the reservoir to the vagina, and a portal for releasing the steroid from the module to the vagina, (c) a platform which integrates the module into a unit sized, shaped and adapted for insertion and retention in a vagina, and (d) a contraceptive program which provides for the controlled release of steroid to produce an antifertility effect over a prolonged period of time.

대표청구항 ▼

A process for manufacturing a device for delivering a drug to a biological environment, which process comprises: (a) shaping a biocompatible tube to a shape and size adapted for placement in the environment; (b) inserting and sealing into one end of said tube a portion of solid polymeric plug; (c) f

A process for manufacturing a device for delivering a drug to a biological environment, which process comprises: (a) shaping a biocompatible tube to a shape and size adapted for placement in the environment; (b) inserting and sealing into one end of said tube a portion of solid polymeric plug; (c) forming a closed hollowed reservoir device by inserting and sealing the remaining portion of said plug into the other end of the tube; (d) positioning a drug inlet in the tube closely adjacent to the plug; (e) positioning an air outlet in the tube closely adjacent to the plug on the other side of the tube; (f) admitting a drug formulation through the inlet while venting air from the reservoir, and continuing such admittance until the reservoir is filled with formulation and the air has been displaced through the outlet; and, (g) removing the inlet and outlet and sealing the tube, thereby providing the device for delivering drug through the tube to the environment at a controlled rate over a prolonged period of time.