초록 ▼

The invention provides new hydrogel forming materials comprising synthetic, hydrophilic, aqueous-insoluble polymer networks formed by copolymerization of a hydrophilic dihydroxyalkyl acrylate or methacrylate, a substantially water insoluble alkyl acrylate or methacrylate, one or more additional hydr

The invention provides new hydrogel forming materials comprising synthetic, hydrophilic, aqueous-insoluble polymer networks formed by copolymerization of a hydrophilic dihydroxyalkyl acrylate or methacrylate, a substantially water insoluble alkyl acrylate or methacrylate, one or more additional hydrophilic comonomers selected from the group of vinylic monomers, acrylates, and methacrylates, and a cross-linking agent. The hydrogels are preferably used for the formation of contact lenses, but may also be used for drug and pesticides delivery devices; dialysis, ultrafiltration and reverse osmosis membranes; implants in surgery and dentistry; and the like.

대표청구항 ▼

A hydrophilic polymer comprising the polymerization product of: a first monomer comprising a dihydroxyalkyl acrylate, a second monomer comprising a substantially water insoluble alkyl acrylate or alkyl methacrylate, the mole ratio of said first monomer to said second monomer varying within the range

A hydrophilic polymer comprising the polymerization product of: a first monomer comprising a dihydroxyalkyl acrylate, a second monomer comprising a substantially water insoluble alkyl acrylate or alkyl methacrylate, the mole ratio of said first monomer to said second monomer varying within the range from about 1:3 to about 20:1; a third monomer comprising a compound selected from the group consisting of: [Figure] (a) where R3 is hydroxyl, alkoxy having 1 to 6 carbon atoms, a sulfonic acid moiety, [Figure] wherein R4 and R5 are independently selected from hydrogen and an unsubstituted or substituted alkyl group having from 1 to about 3 carbon atoms, and R4 and R5 may be combined to form a cyclic group, or [Figure] wherein R4 and R5 are as defined above, and n is an integer from 0 to about 4, except that n must be at least 1 when R3 is hydroxyl; [Figure] (b) where R6 is hydroxyalkoxy having 1 to 6 carbon atoms or －NR7R8 where R7 and R8 are independently selected from hydrogen and lower alkyl groups having 1 to 4 carbon atoms; [Figure] (c) where R9 is hyroxyalkoxy having from 1 to about 6 carbon atoms; and (d) mixtures thereof: the total of the molar quantities of said first and second monmers to the molar quantity of said third monomer being in the range of 1:1 to 1:0.2.