초록 ▼

A nebulizer for use in connection with a lung ventilating system characterized in providing a dual stage atomization of medicament carrying liquid. A first stage develops an aerosol exhibiting an initial, relatively larger average liquid particle size which is introduced to a chamber at a given stag

A nebulizer for use in connection with a lung ventilating system characterized in providing a dual stage atomization of medicament carrying liquid. A first stage develops an aerosol exhibiting an initial, relatively larger average liquid particle size which is introduced to a chamber at a given stagnation pressure. From that chamber, a second atomization is carried out by passing the gas entrained liquid particles through a knife edge orifice to produce a rapid expansion free-jet flow and consequent particle breakdown to achieve a desired particle size distribution.

대표청구항 ▼

Nebulizer apparatus, connectable with a source of gas and with a liquid source comprising: a first atomizer stage chamber for simultaneously communicating with a source of pressurized gas and with said source of liquid for forming by the Bernoulli effect a first particulate dispersion of said liquid

Nebulizer apparatus, connectable with a source of gas and with a liquid source comprising: a first atomizer stage chamber for simultaneously communicating with a source of pressurized gas and with said source of liquid for forming by the Bernoulli effect a first particulate dispersion of said liquid entrained with said gas, the liquid particles of said first particulate dispersion exhibiting an average diameter, D1, and a surface tension, S, and said gas exhibiting a density ro, and including a knife-edge exit orifice having diameter, do, to effect the expulsion through said exit orifice of said first particulate dispersion to impart supersonic velocities to said gas under flow conditions according to the expression: ogur2≥WeS/DI, where ur is the relative velocity between a given said liquid particle and the velocity of said gas, and We is Weber number of value effective to effect a breakdown of said liquid particles to form a second gas entrained particulate dispersion of said liquid having an average particle diameter, DS, less than said diameter, DI; and a flexible tube communicating at one end with a source of gas under relatively low positive pressure, at the other end with a mouthpiece, and between the ends with said exit orifice whereby the second gas entrained particulate dispersion and low positive pressure gas are delivered to the mouthpiece.