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Biochemical avidin-biotin multiple-layer system 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B32B-005/16
  • B32B-009/00
출원번호 US-0114898 (1980-01-24)
발명자 / 주소
  • Giese Roger W. (56 Oakland Ave. Quincy MA 02170)
인용정보 피인용 횟수 : 57  인용 특허 : 3

초록

A multiple-layer process for applying, in alternate, successive layers, the protein, avidin, and a biotin-containing extender material to a solid surface to modify the properties of the surface and to the multiple-layer product so prepared.

대표청구항

A process of modifying the surface properties of a surface, which process comprises: applying alternative, monomolecular, successive layers of first and and second materials to a surface to be modified, the first material comprising avidin and the second material comprising a noncovalent, biotin-mod

이 특허에 인용된 특허 (3)

  1. Eikenberry Jon N. (Rochester NY) Sanford Karl J. (Rochester NY) Sutton Richard C. (Rochester NY), Analytical element for the analysis of liquids under high pH conditions.
  2. Andersson Lars-Olov (Knivsta SEX) Borg Hakan G. (Huddinge SEX) Einarsson Gudrun M. (Upsala SEX), Method of removal of hepatitis virus.
  3. Boguslaski Robert C. (Elkhart IN) Carrico Robert J. (Elkhart IN) Christner James E. (Ann Arbor MI), Specific binding assay with an enzyme modulator as a labeling substance.

이 특허를 인용한 특허 (57)

  1. Bruce J. Bryan ; Stephen Gaalema ; Randall B. Murphy, Apparatus and method for detecting and identifying infectious agents.
  2. Bryan, Bruce J.; Gaalema, Stephen; Murphy, Randall B., Apparatus and method for detecting and identifying infectious agents.
  3. Bryan, Bruce J.; Gaalema, Stephen; Murphy, Randall B., Apparatus and method for detecting and identifying infectious agents.
  4. Nova Michael P. ; Lillig John E. ; Karunaratne Kanchana Sanjaya Gunesekera ; Ewing William ; Satoda Yozo ; Potash Hanan, Automated sorting system for matrices with memory.
  5. Bryan Bruce, Bioluminescent novelty items.
  6. Bryan Bruce, Bioluminescent novelty items.
  7. Bryan Bruce, Bioluminescent novelty items.
  8. Bryan Bruce, Bioluminescent novelty items.
  9. Patch Keith D. (Lexington MA) Morgan Dean T. (Sudbury MA), Chemical enhancement of surface deposition.
  10. Winkler James L. ; Fodor Stephen P. A. ; Buchko Christopher J. ; Ross Debra A. ; Aldwin Lois ; Modlin Douglas N., Combinatorial strategies for polymer synthesis.
  11. Winkler, James L.; Fodor, Stephen P. A.; Buchko, Christopher J.; Ross, Debra A.; Aldwin, Lois; Modlin, Douglas N., Combinatorial strategies for polymer synthesis.
  12. Winkler, James L.; Fodor, Stephen P. A.; Buchko, Christopher J.; Ross, Debra A.; Aldwin, Lois; Modlin, Douglas N., Combinatorial strategies for polymer synthesis.
  13. Winkler, James L.; Fodor, Stephen P. A.; Buchko, Christopher J.; Ross, Debra A.; Aldwin, Lois; Modlin, Douglas N., Combinatorial strategies for polymer synthesis.
  14. Winkler, James L.; Fodor, Stephen P. A.; Buchko, Christopher J.; Ross, Debra A.; Aldwin, Lois; Modlin, Douglas N., Combinatorial strategies for polymer synthesis.
  15. Symons Robert H. (Adelaide AUX), Compounds used as intermediates in the preparations of non-radioactive biological probes.
  16. Patch Keith D. ; Morgan Dean T., Detecting low levels of radionuclides in fluids.
  17. Bruce Bryan, Detection and visualization of neoplastic tissues and other tissues.
  18. Bryan, Bruce, Detection and visualization of neoplastic tissues and other tissues.
  19. Olson John D. ; Zuk Robert F. ; Armenta Richard D. ; Burke Charles R. ; Kung Viola T. ; Sheldon Edward L., Hapten derivatized capture membrane and diagnostic assays using such membrane.
  20. Rosenstein Robert (Ellicott City MD), Immuno-agglutination particle suspensions.
  21. Hillenkamp, Franz, Infrared matrix-assisted laser desorption/ionization mass spectrometric analysis of macromolecules.
  22. Richards, William L.; Ashby, Austin; Ketterer, Matthew; Marshall, Kevin; Harrison, Josh; Mette, Matthew; Richards, Paul; Showalter, Wayne; Cote, Jasmin; Halbert, Phillip C.; Bourgeois, Solene; Metzger, Steven W.; Hance, Ken; Mensack, Meghan; Michel, Carlos; Allers, Elke; Gamage, Dulini; Prisbrey, Landon; Gusyatin, Oleg; Shamsheyeva, Alena; Turng, Ben; Ghusson, Andrew; Reinhardt, Kurt, Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing.
  23. Richards, William L.; Ashby, Austin; Ketterer, Matthew; Marshall, Kevin; Harrison, Josh; Mette, Matthew; Richards, Paul; Showalter, Wayne; Cote, Jasmin; Halbert, Phillip C.; Bourgeois, Solene; Metzger, Steven W.; Hance, Ken; Mensack, Meghan; Michel, Carlos; Allers, Elke; Gamage, Dulini; Prisbrey, Landon; Gusyatin, Oleg; Shamsheyeva, Alena; Turng, Ben; Ghusson, Andrew; Reinhardt, Kurt, Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing.
  24. Landes Greg M. (Northboro MA), Labeled DNA.
  25. Bruce J. Bryan ; Christopher Szent-Gyorgyi, Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items.
  26. Bryan Bruce J. ; Szent-Gyorgyi Christopher, Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items.
  27. Nova Michael P. ; Parandoosh Zahra ; Senyei Andrew E. ; Xiao Xiao-Yi ; David Gary S. ; Satoda Yozo ; Zhao Chanfeng ; Potash Hanan, Matrices with memories and uses thereof.
  28. Prisbrey, Landon; Blackmore, Elise; Hance, Kenneth R.; Metzger, Steven W.; Marshall, Kevin, Membrane-assisted purification.
  29. Jurinke Christian,DEX ; Van den Boom Dirk,DEX ; Koster Hubert, Method for dissociating biotin complexes.
  30. Starzl Timothy W. ; Nunnery David W. ; Robinson MaryBeth ; Hanlin H. John, Method for specific substance and molecule detection.
  31. Stupp Samuel I. ; Hwang Julia, Method for synthesizing organoapatites on to surgical metal alloys.
  32. Yuan,Chong Sheng, Methods for assaying homocysteine.
  33. Yuan, Chong-Sheng, Methods of determining SAM-dependent methyltransferase activity using a mutant SAH hydrolase.
  34. Ashutosh Chilkoti ; Zhongping Yang, Microstamping activated polymer surfaces.
  35. Chilkoti,Ashutosh; Yang,Zhongping; Hyun,Jinho, Microstamping activated polymer surfaces.
  36. Giese Roger W. (56 Oakland Ave. Quincy MA 02170), Process for applying multiple layers of a protein and a ligand extender to a surface and to the multiple-layer system.
  37. Kaetsu Isao (Takasaki JPX) Yoshida Masaru (Takasaki JPX), Process for producing a multi-layered slow release composite.
  38. Nygren Bo H. (Billdal SEX) Stenberg Johan E. (Gothenburg SEX), Process for providing articles with a biocompatible surface layer.
  39. Metzger, Steven W.; Hance, Kenneth Robert, Rapid cell purification systems.
  40. Metzger, Steven W.; Hance, Kenneth Robert, Rapid cell purification systems.
  41. Metzger, Steven W.; Hance, Kenneth Robert, Rapid cell purification systems.
  42. Shamsheyeva, Alena; Howson, David C.; Metzger, Steven W., Rapid determination of microbial growth and antimicrobial susceptibility.
  43. Metzger, Steven W.; Howson, David C.; Goldberg, David A.; Buttry, Daniel A., Rapid microbial detection and antimicrobial susceptibility testing.
  44. Michael P. Nova ; Andrew E. Senyei, Remotely programmable matrices with memories.
  45. Nova Michael P. ; Senyei Andrew E., Remotely programmable matrices with memories.
  46. Nova Michael P. ; Senyei Andrew E. ; David Gary S., Remotely programmable matrices with memories.
  47. Bryan,Bruce; Szent Gyorgyi,Christopher; Szczepaniak,William, Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items.
  48. Starzl Timothy W. ; Nunnery David W. ; Robinson MaryBeth ; Hanlin H. John, Sensing system for specific substance and molecule detection.
  49. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  50. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  51. Royappa, Grace Christy Rani; Perrin, Marilyn H.; Rivier, Jean E.; Vale, Jr., Wylie W.; Riek, Roland, Structure-based modulators of B1 G-protein coupled receptors.
  52. Shakesheff, Kevin; Patel, Nikin; Cannizzaro, Scott M.; Langer, Robert S., Surface coating spatially controlled patterns.
  53. Strohner Pavel,DEX ; Immer Ulrike,DEX, Surfaces coated with streptavidin/avidin.
  54. Michal Eugene T. ; Buchko Christopher J. ; Bigus Stephen J., Therapeutic, diagnostic, or hydrophilic coating for an intracorporeal medical device.
  55. Sommer,Ronald; Schulman,Lloyd; Wijesuriya,Daya C., Use of dual conjugated labels in the elimination of serum interference in immunochromatographic assays.
  56. Luo, Song; Copenhaver, Gregory; Keith, Kevin; Preuss, Daphne, Use of methylated nucleic acid segments for isolating centromere DNA.
  57. Luo,Song; Copenhaver,Gregory; Keith,Kevin; Preuss,Daphne, Use of methylated nucleic acid segments for isolating centromere DNA.
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