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Hemolysing solution preparing hemolysed blood having a stabilized glucose content 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/48
  • C09K-003/00
출원번호 US-0096347 (1979-11-21)
우선권정보 DE-2850603 (1978-11-22)
발명자 / 주소
  • Vormbrock Rolf (Darmstadt DEX) Helger Roland (Darmstadt DEX)
출원인 / 주소
  • Merck Patent Gesellschaft mit beschrnkter Haftung (Darmstadt DEX 03)
인용정보 피인용 횟수 : 26  인용 특허 : 7

초록

A hemolysing solution for use in the determination of glucose in a whole blood sample which comprises (a) a buffer providing a pH of about 6-8, (b) sodium chloride, (c) a surface active agent and, (d) a chelating agent which in the presence of component (c) serves as a stabilizer against glycolysis

대표청구항

In a hemolysing solution used in the determination of glucose in a whole blood sample, consisting essentially of a lysing reagent and a glycolysis inhibitor which inhibits glycolysis in the hemolysate obtained by contacting the blood sample with the hemolysing solution, the improvement wherein the h

이 특허에 인용된 특허 (7)

  1. Louderback Allan L. (Temple City CA) Fontana Anthony J. (Glendora CA), Calibrating fluid for blood cell counting and hemoglobin determination.
  2. Stroupe Stephen D. (Libertyville IL) Moore Edwin G. (Libertyville IL), Determination of glycosylated hemoglobin in blood.
  3. Das Manik L. (Crestwood MO), Lyophilized human hemoglobin standard for colorimetric determination of total hemoglobin.
  4. Lancaster Robert G. (Baltimore MD), Lysing reagent.
  5. Acuff Kenneth J. (Clinton OH), Method to determine a diagnostic indicator of blood sugar condition, and, a liquid chromatographic microcolumn therefor.
  6. Armstrong Douglas (Coral Springs FL), Multi-purpose diluent for use in blood analysis by electronic instrumentation of the coulter type.
  7. Armstrong ; Douglas, Stabilized hematological reagent solutions.

이 특허를 인용한 특허 (26)

  1. Edmondson Sherburne M. (Sunnyvale CA) Luna Carlos E. (Campbell CA), Blood diluent for red blood cell analysis.
  2. Wong Sie Ting ; Hiltibran Robert G. ; Huang Tung-Ming, Diagnostic assay requiring a small sample of biological fluid.
  3. Gilmour,Steven B.; Modzelewski,Brent E., Distinguishing test types through spectral analysis.
  4. Modzelewski, Brent E.; Gilmour, Steven B., Distinguishing test types through spectral analysis.
  5. Guardino Robert F. (Rochester NY) Belly Robert T. (Webster NY), Inhibition of reduction activities of leukocytes.
  6. Modzelewski, Brent E.; Gilmour, Steven B.; Roth, G. Thomas; Bell, Douglas E., Method for determining concentration of an analyte in a test strip.
  7. Phillips, Roger; McGarraugh, Geoffery; Jurik, Franklin A.; Underwood, Raymond D., Method for the determination of glucose employing an apparatus emplaced matrix.
  8. Yani,Adva; Huang,Paing C., Method of determining the concentration of an analyte in a physiological sample.
  9. Paolini, Gregory P.; Roth, G. Thomas; Modzelewski, Brent E., Method of strip insertion detection.
  10. Modzelewski, Brent; Rounds, George, Method of using a protective test strip platform for optical meter apparatus.
  11. Phillips Roger (Palo Alto CA) McGarraugh Geoffery (Scotts Valley CA) Jurik Frank (San Mateo CA) Underwood Ray (Red Bluff CA), Minimum procedure system for the determination of analytes.
  12. Phillips, Roger; McGarraugh, Geoffery; Jurik, Frank; Underwood, Ray, Minimum procedure system for the determination of analytes.
  13. Carter James H. (Ft. Lauderdale FL) Ledis Stephen L. (Hialeah FL) Crews Harold R. (Miami FL) Sena Ted (Miami FL) Larsen Fred L. (Miami Lakes FL), Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes.
  14. Thornthwaite Jerry T. (117 Blakemore Cir. Johnson City TN 37601), Nuclear isolation medium and procedure for separating cell nuclei.
  15. Thornthwaite Jerry T. (117 Blakemore Cir. Johnson City TN 37601), Nuclear isolation medium and procedure for separating cell nuclei.
  16. Zander Rolf (Reinhold-Schneider-Str. 1 Mainz DEX) Lang Werner (Alter Ruh-Weg Mainz DEX) Wolf Hans U. (Lisztstrasse 10 Neu-Ulm DEX), Process and reagent for determination of the hemoglobin content of blood.
  17. Kenney Andrew C.,GBX ; Adewunmi Maria D.,GBX, Process for eliminating labile glycohaemoglobin from a sample.
  18. Brent Modzelewski ; George Rounds, Protective test strip platform.
  19. Naser, Werner; Duelffer, Thomas; Herrmann, Rupert; Kobold, Uwe; von der Eltz, Herbert, Ready-to-use whole blood collection vessel.
  20. Larsen Fred L. (Miami Lakes FL), Reagent for combined diluting and lysing whole blood.
  21. Yani,Adva; Huang,Paing C., Reagent test strip for analyte determination having a hemolyzing agent.
  22. Adva Yani ; Paing C. Huang, Reagent test strip for analyte determination having hemolyzing agent.
  23. Phillips, Roger; McGarraugh, Geoffery; Jurik, Franklin A.; Underwood, Raymond D., Reagents test strip adapted for receiving an unmeasured sample while in use in an apparatus.
  24. Phillips, Roger; McGarraugh, Geoffery; Jurik, Franklin A.; Underwood, Raymond D., Reagents test strip with alignment notch.
  25. Phillips Roger ; McGarraugh Geoffery ; Jurik Franklin A. ; Underwood Raymond D., Reflectance measurement of analyte concentration with automatic initiation of timing.
  26. Phillips Roger (Palo Alto CA) McGarraugh Geoffery (Scotts Valley CA) Jurik Franklin A. (San Mateo CA) Underwood Raymond D. (Red Bluff CA), Whole blood glucose test strip.
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