초록 ▼

The mixed phase packing material of this invention, enables rapid separation of multi-sited biopolymers. This separation is achieved by “tailoring”the distance between organo-silyl groups covalently bonded to the rigid support at the Angstrom distance needed for reversible separation of the biopolym

The mixed phase packing material of this invention, enables rapid separation of multi-sited biopolymers. This separation is achieved by “tailoring”the distance between organo-silyl groups covalently bonded to the rigid support at the Angstrom distance needed for reversible separation of the biopolymers of interest and “capping”other sterically available active sites on the support with a relatively inert compound.

대표청구항 ▼

A mixed phase composition comprising a porous particle suitable for use in chromatography having a first residue covalently bonded, to less than the maximum number of sterically available support matrix active sites, said first residue being capable of separating multiple-sorbable-sited compounds, s

A mixed phase composition comprising a porous particle suitable for use in chromatography having a first residue covalently bonded, to less than the maximum number of sterically available support matrix active sites, said first residue being capable of separating multiple-sorbable-sited compounds, said particle also having a second residue covalently bonded to other of the sterically available support matrix active sites, said second residue being inert or substantially inert to said compounds; said first and second residues being directly attached to said active sites.