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Method and apparatus for introducing samples to a mass spectrometer 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B01D-059/44
출원번호 US-0038264 (1979-05-11)
우선권정보 JP-0111130 (1978-09-08)
발명자 / 주소
  • Takeuchi Tsugio (Nagoya JPX) Tsuge Shin (Nagoya JPX) Hirata Yukio (Toyohashi JPX) Mochizuki Koichi (Tsushima JPX)
출원인 / 주소
  • Japan Spectroscopic Co. Ltd (Tokyo JPX 03)
인용정보 피인용 횟수 : 47  인용 특허 : 5

초록

Simplified method and apparatus for connecting a liquid chromatograph, particularly of a high-performance type, directly to a mass spectrometer without using any complicated devices conventionally available, for the purpose of continuous and stable mass spectrometric measurement of a liquid sample,

대표청구항

A method for continuously introducing a large molecular weight compound in vapor and fine particle form to an ion source of a mass spectrometer which comprises: supplying a nebulizing gas to a nebulizing means; spurting said nebulizing gas from a nozzle portion of said nebulizing means while continu

이 특허에 인용된 특허 (5)

  1. Studenick David K. (Rockville MD), Fluid sampling device.
  2. Miyagi ; Hiroyuki ; Nakajima ; Fumito ; Arikawa ; Yoshijiro, Interface for use in a combined liquid chromatography - mass spectrometry system.
  3. Briggs Walton E. (Lynnfield MA), Leak detection system with wire probe.
  4. Horton Robert L. (Bartlesville OK), Liquid chromatograph/mass spectrometer interface.
  5. McLafferty Fred W. (Ithaca NY) Hertel Robert H. (Pasadena CA) Villwock Robert D. (Glendora CA), Mass spectrometric system for rapid, automatic and specific identification and quantitation of compounds.

이 특허를 인용한 특허 (47)

  1. Griffiths Frank K. (Bracknell GB3), Air withdrawing sampling probes for a contraband detection system.
  2. Cooks Robert G. (West Lafayette IN) Bier Mark E. (West Lafayette IN) Brodbelt Jennifer S. (West Lafayette IN) Tou James C. (Midland MI) Westover Lemoyne B. (Midland MI), Capillary membrane interface for a mass spectrometer.
  3. Knauer Wolfgang (Malibu CA), Carrier gas cluster source for thermally conditioned clusters.
  4. Voss, Guenter F., Cycloidal mass spectrometer.
  5. Voss, Guenter F.; Celo, Alan B.; Duryea, Anthony N., Cycloidal mass spectrometer with time of flight characteristics and associated method.
  6. Mizuno Tokuo (Tokyo JPX), Device for coupling a liquid chromatograph and a mass spectrometer.
  7. Thakur,Rohan A., Electrospray ion source apparatus.
  8. Broadbent Carolyn C. (Los Altos CA) Fjeldsted John C. (Redwood City CA), Heating system for GC/MS instruments.
  9. Vestal Marvin L. (Houston TX), Interface for coupling liquid chromatography to solid or gas phase detectors.
  10. Brandt Rune (St.-Heddinge CA DKX) Nordman Robert (Palo Alto CA), Interface for liquid chromatography-mass spectrometry systems.
  11. Sharp Daryl (317 Woodhaven Chapel Hill NC 27514), Internal mass spectrometer interface to a gas chromatograph.
  12. Duryea Anthony N. (Cheswick PA), Ion detection apparatus.
  13. Duryea Anthony N. (Cheswick PA), Ion detector and associated removable ionizer inlet assembly.
  14. Atsumu Hirabayashi JP; Minoru Sakairi JP; Yasuaki Takada JP; Hideaki Koizumi JP; Kaoru Umemura JP, Ion source and mass spectrometer instrument using the same.
  15. Hirabayashi Atsumu,JPX ; Sakairi Minoru,JPX ; Takada Yasuaki,JPX ; Koizumi Hideaki,JPX ; Umemura Kaoru,JPX, Ion source and mass spectrometer instrument using the same.
  16. Hirabayashi, Atsumu; Sakairi, Minoru; Takada, Yasuaki; Koizumi, Hideaki; Umemura, Kaoru, Ion source and mass spectrometer instrument using the same.
  17. Hirabayashi,Atsumu; Hashimoto,Yuichiro, Ion source and mass spectrometric apparatus.
  18. Kobayashi Tsutomu (Tokyo JPX), Ion source for mass spectrometer.
  19. Henion John D. (Trumansburg NY) Covey Thomas R. (Houston TX) Bruins Andries P. (Leek NLX), Ion spray apparatus and method.
  20. Vestal Marvin L. (Houston TX) Blakley Calvin R. (Kingwood TX) Fergusson Gordon J. (Claremont CA), Ion vapor source for mass spectrometry of liquids.
  21. Lee Edgar D. (Olathe KS) Covey Thomas R. (Ithaca NY) Henion John D. (Ithaca NY), Liquid junction coupling for capillary zone electrophoresis/ion spray spectrometry.
  22. Xian-Wei Yao, Liquid transportation system for microfluidic device.
  23. Bajic, Stevan, Mass spectrometer.
  24. Kumano, Shun; Sugiyama, Masuyuki; Hashimoto, Yuichiro; Hasegawa, Hideki; Yamada, Masuyoshi; Nishimura, Kazushige; Morokuma, Hidetoshi, Mass spectrometer and mass analyzing method for efficiently ionizing a sample with less carry-over.
  25. Hirabayashi Atsumu,JPX ; Hirabayashi Yukiko,JPX ; Sakairi Minoru,JPX ; Takada Yasuaki,JPX ; Nabeshima Takayuki,JPX ; Koizumi Hideaki,JPX, Mass spectrometer and mass spectrometry method for analyzing compounds contained in a solution.
  26. Hirabayashi Atsumu,JPX ; Hirabayashi Yukiko,JPX ; Sakairi Minoru,JPX ; Takada Yasuaki,JPX ; Nabeshima Takayuki,JPX ; Koizumi Hideaki,JPX, Mass spectrometer and mass spectrometry method for analyzing compounds contained in a solution.
  27. Voss, Guenter F., Mass spectrometer and related ionizer and methods.
  28. Mehdi Moini ; Longfei Jiang, Mass spectrometer apparatus for analyzing multiple fluid samples concurrently.
  29. Tou James C. (Midland MI), Mass spectrometer sampling system for a liquid stream.
  30. Lewis Ivor A. S. (Knutsford GBX) Smith David C. (Northwich GBX), Mass spectrometers.
  31. Boulin Yves (Chilly Mazarin FRX) Cesario Jean (Verrieres le Buisson FRX) Landeau Bernard (Marcoussis FRX), Material ionizing device.
  32. Park, Melvin A.; Wang, Houle, Method and apparatus for a nanoelectrosprayer for use in mass spectrometry.
  33. Park,Melvin A.; Wang,Houle, Method and apparatus for a nanoelectrosprayer for use in mass spectrometry.
  34. Biemann Klaus (Alton Bay NH) Gagel John J. (Cumberland Center ME), Method and apparatus for continuous collection of chromatographic effluent.
  35. Willoughby Ross C. (Pittsburgh PA) Buchner James D. (Pittsburgh PA), Method and apparatus for introduction of fluid streams into mass spectrometers and other gas phase detectors.
  36. Willoughby Ross C. (Pittsburgh PA), Method and apparatus for introduction of liquid effluent into mass spectrometer and other gas-phase or particle detector.
  37. Vestal Marvin L. (Houston TX) Blakely Calvin R. (Kingwood TX) Fergusson Gordon J. (Claremont CA), Method and means for vaporizing liquids by means of heating a sample capillary tube for detection or analysis.
  38. Vestal Marvin L. (Houston TX) Blakely Calvin R. (Kingwood TX) Fergusson Gordon J. (Claremont CA), Method and means for vaporizing liquids for detection or analysis.
  39. Browner Richard F. (Atlanta GA) Willoughby Ross C. (Wilmington DE), Monodisperse aerosol generator.
  40. Browner Richard F. (Atlanta GA) Willoughby Ross C. (Wilmington DE), Monodisperse aerosol generator.
  41. Browner Richard F. (Atlanta GA) de Haseth James A. (Athens GA), Monodisperse aerosol generator for use with infrared spectrometry.
  42. Dale R. Pfost ; Sheila H. DeWitt ; Chao Lin ; Rolf E. Swenson ; Robert D. Juncosa ; Gary J. Schnerr ; Sheldon M. Kugelmass, Multiple fluid sample processor and system.
  43. Wang Lanqing ; Browner Richard F., Oscillating capillary nebulizer.
  44. Wang Lanqing ; Browner Richard F., Oscillating capillary nebulizer.
  45. Browner Richard F. ; Shou Zhenyu, Oscillating capillary nebulizer with electrospray.
  46. Badawy, Tamer H.; Estefanous, Fadi; Henein, Naeim A., Simultaneous ion sensing and gas sampling in combustion engine cylinders and other combustion systems.
  47. Hurst James (San Jose CA), Transfer line for mass spectrometer apparatus.
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