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Process and apparatus for freezing living cells

국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) F25B-013/00   
미국특허분류(USC) 165/12 ; 165/30 ; 165/61 ; 62/62
출원번호 US-0049302 (1979-06-18)
발명자 / 주소
출원인 / 주소
인용정보 피인용 횟수 : 25  인용 특허 : 3
초록
▼

The process for freezing cell suspensions by locating the suspension in a freezing chamber and simultaneously monitoring the temperature of the suspended cells and of the chamber. The cooling of the chamber is regulated at predetermined rates in response to given temperature levels of the sample. The cooling chamber includes a fan, a heater, and a source of refrigerant. The process includes the steps of selectively decreasing and increasing the temperature of the freezing chamber responsive to predetermined temperature points on the freezing curve of the...

대표
청구항
▼

Apparatus for freezing cell suspension samples comprising: a housing having walls defining therein an enclosed oval duct forming a continuously circulating passage, one section of said duct constituting a freezing section for the location of a plurality of separately packaged samples to be frozen and having, an inlet to said passage spaced from said freezing section, for the introduction of a refrigerant into said duct, a heating unit located in said duct between said inlet and said freezing section downstream of said freezing section for heating said re...

이 특허에 인용된 특허 (3)

  1. Strehler John Frederick (1597 Prestwick Grosse Pointe Woods MI 48236) Mikoliczeak John Joseph (32261 Arlington Drive Birmingham MI 48009) Strehler Kirk Robert (22462 Ardmore Park St. Clair Shores MI . Method and apparatus for preserving biological materials. USP1977064030314.
  2. Chmiel ; Horst. Method of and apparatus for the deep freezing of biological substances. USP1978084107937.
  3. Williams ; Thomas E. ; Cygnarowicz ; Thomas A.. System for and method of freezing biological tissue. USP1978104117881.

이 특허를 인용한 특허 피인용횟수: 25

  1. Angelier Nicole (Echirolles FRX) Bionda Joseph (Voiron FRX) Thonnelier Jean-Yves (Sassenage FRX). Apparatus for freezing by means of a cryogenic liquid biological products placed in straws. USP1988114783973.
  2. Kim, Su-Cheong; Shin, Jong-Min; Lee, Su-Won; Kim, Cheol-Hwan; Kwon, Yong-Chol; Son, Ku-Young. Apparatus for supercooling, and method of operating the same. USP2011118061150.
  3. Wisniewski, Richard. Cryopreservation system with controlled dendritic freezing front velocity. USP2003106635414.
  4. Angelier Nicole (Echirolles FRX) Colomb Francois (Grenoble FRX). Device for freezing biological products. USP1984124485641.
  5. Hattori, Wataru. Method and apparatus for adjusting device used at low temperature without deterioration thereof. USP2003096615605.
  6. Hattori, Wataru. Method and apparatus for adjusting device used at low temperature without deterioration thereof. USP2003016505471.
  7. Miller Jeremy P. (Oxon GBX) Smith Colin D. (Surrey GBX). Method and apparatus for freezing products. USP1990044914927.
  8. Livne Avinoam (Beersheva ILX). Method and apparatus for heating and/or cooling objects simultaneously at different preselected temperatures. USP1987074679615.
  9. Cheng, Alan. Method and system for controlled rate freezing of biological material. USP2014088794012.
  10. Kasai ; deceased Yoichi (late of Sapporo JPX by Motoko Kasai ; representative) Kawamura Akio (Sapporo JPX) Nakanishi Yoshimi (Sapporo JPX) Kakita Akira (Sapporo JPX) Tsuburaya Toshihiko (Sapporo JPX). Method of fabricating frozen fine liver piece for artificial liver, apparatus for freezing the same and freezing vessel. USP1991014987921.
  11. Kasai ; deceased Yoichi (Sapporo JPX by Motoko Kasai ; personal representative) Kawamura Akio (Sapporo JPX) Nakanishi Yoshimi (Sapporo JPX) Kakita Akira (Sapporo JPX) Tsuburaya Toshihiko (Sapporo JPX. Method of fabricating frozen fine liver pieces for artificial liver, apparatus for freezing the same, and freezing vesse. USP1989114883452.
  12. Liu Lee-Cheng ; Lai Shoupeng. Method of producing adenoviral vector stocks. USP2001016168941.
  13. Richard Daniel D. (Sedona AZ). Multichamber storage apparatus and related method. USP1991075029447.
  14. Clark Thomas S. (2177 Webster St. Palo Alto CA 94301) Kennedy William S. (3043 Emerson Ave. Palo Alto CA 94306). Passive temperature control shipment container. USP1985044509587.
  15. Knippscheer Hermann (Baldwin NY) Richard Daniel D. (Sedona AZ). Storage apparatus, particularly with automatic insertion and retrieval. USP1991065022236.
  16. Voute,Nicolas; Lok,Maxime N.; Leonard,Leonidas Cartwright; Hughes,Timothy Gerard; Wisniewski,Richard. Systems and methods for freezing and storing biopharmaceutical material. USP2006026996995.
  17. Brown, David C.; Cutting, Jonathan; Lee, Eric K.; Voute, Nicolas; Woodard, Brian J.. Systems and methods for freezing, mixing and thawing biopharmaceutical material. USP2005096945056.
  18. Brown,David C.; Cutting,Jonathan; Lee,Eric K.; Voute,Nicolas; Woodard,Brian J.. Systems and methods for freezing, mixing and thawing biopharmaceutical material. USP2006117137261.
  19. Voute, Nicholas; Lok, Maxime N.; Brown, David C.; Kendall, James W.; Geiselhart, Edward. Systems and methods for freezing, storing and thawing biopharmaceutical material. USP2004026684646.
  20. Voute, Nicholas; Lok, Maxime N.; Brown, David C.; Kendall, James W.; Geiselhart, Edward. Systems and methods for freezing, storing and thawing biopharmaceutical material. USP2004096786054.
  21. Voute, Nicolas; Lee, Eric K.; Yakoushkin, Dimitry. Systems and methods for freezing, storing and thawing biopharmaceutical materials. USP2014108863532.
  22. Voute, Nicolas; Lee, Eric K.; Yakoushkin, Dimitry. Systems and methods for freezing, storing and thawing biopharmaceutical materials. USP2011108028532.
  23. Voute,Nicolas; Lee,Eric K.; DeBeers,James Edward; Woodward,Brian J.; Lee,Ngee Jenn. Systems and methods for freezing, storing, transporting and thawing biopharmaceutical material. USP2006097104074.
  24. Voute,Nicolas; Lee,Eric K.; DeBeers,James Edward; Woodard,Brian J.; Lee,Ngee Jenn. Systems and methods for freezing, storing, transporting, and thawing biopharmacuetical material. USP2008047353658.
  25. King Eddie W. (Atlanta GA) Hughes ; IV Robert D. (Smyrna GA). Temperature-based control for energy management system. USP1984124485633.

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