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Controlled release formulations of orally-active medicaments

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/22
  • A61K-009/30
  • A61K-009/52
  • A61K-009/56
출원번호 US-0194453 (1980-10-17)
발명자 / 주소
  • Dunn James M. (Shreveport LA) Lampard John F. (Shreveport LA)
출원인 / 주소
  • Boots Pharmaceuticals, Inc. (Nottingham GB2 03)
인용정보 피인용 횟수 : 42  인용 특허 : 2

초록

An improved tablet formulation is provided comprising an effective amount of an active therapeutic agent, especially an acidic therapeutic agent such as aspirin, a release-controlling agent, and an erosion-promoting agent in relative amounts to provide a criticality factor of less than 450, and in p

대표청구항

A compressed, controlled-release tablet suitable for oral administration, said tablet consisting essentially of an effective amount of an orally-active therapeutic agent selected from aspirin and a nonsteroidal arylalkanoic anti-inflammatory agent, a release-controlling agent, and an erosion-promoti

이 특허에 인용된 특허 (2)

  1. Leslie Stewart Thomas (Aberdeen SC), Slow release pharmaceutical compositions.
  2. Kornblum Saul S. (Springfield NJ) Stoopak Samuel B. (West Caldwell NJ), Sustained release tablet formulations.

이 특허를 인용한 특허 (42)

  1. Baichwal Anand R. (Wappingers Falls NY), Agglomerated hydrophilic complexes with multi-phasic release characteristics.
  2. Baichwal Anand R. (Wappingers Falls NY) Staniforth John N. (Bath GB2), Agglomerated hydrophilic complexes with multi-phasic release characteristics.
  3. Baichwal Anand R. (Wappingers Falls NY) Staniforth John N. (Bath GB2), Agglomerated hydrophilic complexes with multi-phasic release characteristics.
  4. Dunn James M. (Littleton CO) Haas Ronald T. (Highland Ranch CO), Constant order release, solid dosage indomethacin formulation and method of treating arthritis and other inflammatory co.
  5. Odidi, Isa; Odidi, Amina, Controlled release formulations using intelligent polymers.
  6. Frisbee Steven E. (Town of New Scotland ; Albany County NY), Controlled-release, low-dose aspirin formulation and method of treating vascular occlusive disease therewith.
  7. Lenaerts, Vincent; Beck, Roland Herwig Friedrich; Van Bogaert, Elsie; Chouinard, Francois; Hopcke, Reiner; Desevaux, Cyril, Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture.
  8. Streuff Bernhard (Cologne DEX) Ptter ; deceased Johann (late of Wuppertal DEX by Elisabeth Ptter ; sole heiress), Delayed-action acetylsalicylic acid formulations for oral administration.
  9. Baichwal Anand R. (Poughkeepsie NY) Staniforth John N. (Bath GB2), Directly compressible sustained release excipient.
  10. Patel Nagin K. (1914 W. 5th St. Brooklyn NY 11223), Drug in bead form and process for preparing same.
  11. Fegely, Kurt; Tasker, Simon; Martin, Lawrence, Enteric coatings for orally ingestible substrates.
  12. Cefali, Eugenio A.; Bova, David J., Intermediate release nicotinic acid compositions for treating hyperlipidemia.
  13. Cefali, Eugenio A., Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics.
  14. Kushla, Gregory P.; Lai, Jin-Wang; Polli, Gerald P., Method of making ibuprofen and narcotic analgesic compositions.
  15. Bova David J., Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night.
  16. Cefali, Eugenio A.; Bova, David J., Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia.
  17. Legrand, Valérie; Castan, Catherine; Meyrueix, Rémi; Soula, Gérard, Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles.
  18. Bova David J., Nicotinic acid compositions for treating hyperlipidemia and related methods therefor.
  19. Bova, David J, Nicotinic acid compositions for treating hyperlipidemia and related methods therefor.
  20. Castan, Catherine; Guimberteau, Florence; Meyrueix, Rémi, Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s).
  21. Castan, Catherine; Guimberteau, Florence; Meyrueix, Rémi, Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s).
  22. Radebaugh Galen W. (Chester NJ) Murtha John L. (Holland PA) Glinecke Robert (Glenside PA), Oral sustained release pharmaceutical formulation and process.
  23. Talwar, Naresh; Sen, Himadri; Staniforth, John N., Orally administered drug delivery system providing temporal and spatial control.
  24. Rudnic Edward M. ; Burnside Beth A. ; Flanner Henry H. ; Wassink Sandra E. ; Couch Richard A. ; Pinkett Jill E., Osmotic drug delivery system.
  25. Rudnic, Edward M.; Burnside, Beth A.; Flanner, Henry H.; Wassink, Sandra E.; Couch, Richard A.; Pinkett, Jill E., Osmotic drug delivery system.
  26. Zuccarelli, Jean-Marc; Chauveau, Charles Andr?; DeMichelis, Gilles; Jean, Karine, Particles coated with granulated crystalline ibuprofen.
  27. Kasica James J. ; Thomas David J. ; Zallie James P., Pharmaceutical products containing thermally-inhibited starches.
  28. Moro Luigi (Cairate ITX) Maffione Grazia (Milan ITX) Neri Guido (Milan ITX) Rigamonti Alessandro (Milan ITX), Pharmaceutical sustained-release compositions.
  29. Pinkus Alvin G., Polyester/carboxylic acid composite materials.
  30. Khanna Satish C. (Bottmingen CHX), Solid, stable dosage forms with an elastic film coating.
  31. Edward M. Rudnic ; Beth A. Burnside ; Henry H. Flanner ; Sandra E. Wassink ; Richard A. Couch ; Jill E. Pinkett, Soluble form osmotic dose delivery system.
  32. Rudnic Edward M. ; Burnside Beth A. ; Flanner Henry H. ; Wassink Sandra E. ; Couch Richard A. ; Pinkett Jill E., Soluble form osmotic dose delivery system.
  33. Davis, Robert D.; Blume, Ralph W.; Keyser, Donald Jeffrey, Sustained release formulations of guaifenesin and additional drug ingredients.
  34. Davis, Robert D.; Blume, Ralph W.; Keyser, Donald Jeffrey, Sustained release of guaifenesin.
  35. Davis, Robert D.; Blume, Ralph W.; Keyser, Donald Jeffrey, Sustained release of guaifenesin combination drugs.
  36. Davis, Robert D.; Blume, Ralph W.; Keyser, Donald Jeffrey, Sustained release of guaifenesin combination drugs.
  37. Ghebre-Sellassie Isaac (Stanhope NJ) Nesbitt ; Jr. Russell U. (Somerville NJ) Iyer Uma (Mendham NJ) Fawzi Mahdi B. (Flanders NJ), Sustained release pharmaceutical preparations.
  38. Uemura Toshinobu (Kishiwada JPX) Shinooka Kiyohide (Nishinomiya JPX) Kajiho Tokuaki (Kobe JPX), Sustained release tablet.
  39. Goudy ; Jr. Paul R. (Bayside WI) Cassedy Linn W. (Roselle IL) Whitaker Thomas S. (Bartlett IL), Tablet granulation.
  40. Scapinelli Bruno (Lamorlaye FRX), Tablet having the shape of a capsule, process and device for its preparation.
  41. Pinkus A. George, Tablets or biologically acceptable implants for long-term antiinflammatory drug release.
  42. Chang Yunik (Toms River NJ), Transdermal drug delivery using a dual permeation enhancer and method of performing the same.
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