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Drug dispensers comprising a flat body composed of a drug solute phase dispersed in a continuous polymer matrix phase in which the release rate of drug from the body is substantially constant and is controlled by the rate at which the drug solute phase dissolves in the continuous polymer matrix phas

Drug dispensers comprising a flat body composed of a drug solute phase dispersed in a continuous polymer matrix phase in which the release rate of drug from the body is substantially constant and is controlled by the rate at which the drug solute phase dissolves in the continuous polymer matrix phase. Such control and constancy are realized by establishing specific correlations between the diffusion coefficient, dissolution rate constant, and thickness of the body.

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An active agent dispenser consisting essentially of a flat body consisting essentially of a particulate active agent solute phase dispersed in a continuous matrix phase that is permeable to the active agent solute phase wherein the following conditions are met (a) D>>K where D is the diffusion coeff

An active agent dispenser consisting essentially of a flat body consisting essentially of a particulate active agent solute phase dispersed in a continuous matrix phase that is permeable to the active agent solute phase wherein the following conditions are met (a) D>>K where D is the diffusion coefficient of the active agent solute phase in the matrix phase in cm2/sec and K is the dissolution rate constant of the active agent solute phase in the matrix phase in cm/sec and (b) Kl/D is less than about 0.06 where K and D are as defined previously and l is the thickness of said body in cm whereby the rate at which active agent is dispensed is (i) controlled by the rate at which the active agent solute phase dissolves in the matrix phase, and (ii) substantially constant.