There are provided compounds of the formula: [Figure] wherein R is an adamantoyl group substituted with a lower alkyl group, a lower alkoxy group, a hydroxy group, a lower alkanoyloxy group, an aroyloxy group, a halogen atom, an acetamido group, a nitro group, an azide group, a trifluoromethyl group
There are provided compounds of the formula: [Figure] wherein R is an adamantoyl group substituted with a lower alkyl group, a lower alkoxy group, a hydroxy group, a lower alkanoyloxy group, an aroyloxy group, a halogen atom, an acetamido group, a nitro group, an azide group, a trifluoromethyl group or a phenyl group which may be substituted with a nitro group, a halogen atom, a lower alkyl group or a lower alkoxy group and a process producing them. These compounds are useful as antitumor agents and immunosuppressants.
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A compound of the formula [Figure] wherein R is adamantoyl substituted with 1-3 substituents selected from the group consisting of lower alkyl, lower alkoxy, hydroxy, lower alkanoyloxy, aroyloxy, halogen, acetamido, nitro, an azide group, trifluoromethyl, or phenyl which may be substituted with nitr
A compound of the formula [Figure] wherein R is adamantoyl substituted with 1-3 substituents selected from the group consisting of lower alkyl, lower alkoxy, hydroxy, lower alkanoyloxy, aroyloxy, halogen, acetamido, nitro, an azide group, trifluoromethyl, or phenyl which may be substituted with nitro, halogen, lower alkyl or lower alkoxy. An immunosuppressant composition which comprises an immunosuppressive amount of a compound of claim 1 as an active ingredient and a pharmaceutically acceptable carrier or diluent.
Satzinger Gerhard (Denzlingen DEX) Herrmann Manfred (St. Peter DEX) Fritschi Edgar (St. Peter DEX) Weiershausen Ute (Gundelfingen DEX), N-phenylbenzamide derivatives.
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