초록 ▼

Foams having aspartase-producing microorganisms bound to the foam are made from polyurethane prepolymers which are capped with polyisocyanates, including diisocyanates, derived from methylene-bis (phenyl isocyanate) which is commonly known as MDI. These MDI based foams are hydrolysis resistant as co

Foams having aspartase-producing microorganisms bound to the foam are made from polyurethane prepolymers which are capped with polyisocyanates, including diisocyanates, derived from methylene-bis (phenyl isocyanate) which is commonly known as MDI. These MDI based foams are hydrolysis resistant as compared to the previously used TDI based foams. The foams can be used to produce L-aspartic acid under high pH conditions.

대표청구항 ▼

A water insoluble, hydrolysis resistant, hydrophilic polyether polyurea polyurethane foam having aspartase-producing microorganisms bound to the foam prepared by reacting under foaming conditions an aqueous mixture containing a culture of aspartase-producing microorganisms and a hydrophilic polyethe

A water insoluble, hydrolysis resistant, hydrophilic polyether polyurea polyurethane foam having aspartase-producing microorganisms bound to the foam prepared by reacting under foaming conditions an aqueous mixture containing a culture of aspartase-producing microorganisms and a hydrophilic polyether polyurethane prepolymer, said foam having a weight ratio of polyurea polyurethane polymer to microorganisms in the foam ranging from about 2 to about 4, a weight ratio of prepolymer to water is from about 2 to about 0.5, and said prepolymer having an isocyanate functionality in excess of 2 but not greater than 8 with at least 50 mole % of the alkylene oxide units in the polyether segments of the polyurethane being ethylene oxide, and obtained by reacting a poly(oxy-C2-4alkylene) diol having at least about 50% by weight of oxyethylene groups. a diphenylmethane diisocyanate-containing isocyanate product with a functionality of greater than 2.0 comprising a mixture of diphenylmethane diisocyanate and isocyanate containing derivatives of diphenylmethane diisocyanate, and a polyol cross-linking agent having 3 or 4 hydroxyl equivalents per mole.