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Process for preparing polynucleotides 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07H-019/10
  • C07H-019/20
  • C07H-021/02
  • C07H-021/04
출원번호 US-0247144 (1981-03-24)
발명자 / 주소
  • Caruthers Marvin H. (Boulder CO) Matteucci Mark D. (Boulder CO)
출원인 / 주소
  • University Patents, Inc. (Norwalk CT 02)
인용정보 피인용 횟수 : 851  인용 특허 : 0

초록

New and useful intermediate nucleotides bound to an inorganic polymer support, including the preparation thereof, and processes for the conversion to oligonucleotides which are especially useful for the synthesis of polynucleotides, particularly ribonucleic (RNA) and deoxyribonucleic acids (DNA).

대표청구항 ▼

A modified inorganic polymer represented by the formula: [Figure] wherein P is an inorganic polymer linked to the 3′or 5′－O－of the nucleoside through a base hydrolyzable covalent bond; R is H or a blocking group; R1 is a hydrocarbyl radical containing up to 10 carbons; each B is a nucleoside or deox

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  145. Gemba, Takefumi, Chiral nucleic acid adjuvant.
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  146. Gemba, Takefumi; Nagata, Ryoichi; Torikai, Yusuke, Chiral nucleic acid adjuvant having antitumor effect and antitumor agent.
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  148. Krotz, Achim; Capaldi, Daniel C.; Gaus, Hans-Joachim Josef; Turney, Brett, Chloral-free DCA in oligonucleotide synthesis.
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  150. Letsinger Robert L. (Wilmette IL), Cholesteryl modified oligonucleotides.
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  151. Patrick S. Stayton, Circularly permuted biotin binding proteins.
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  154. Allen, Antonette C. P.; Angelly, Tracy S.; Lawrence, Tammy; Olson, Sheri J.; Rabin, Mark B., Coding sequence haplotype of the human BRCA1 gene.
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  156. Mason, Nicola; Paterson, Yvonne, Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers.
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  157. Shigemura, Rhondi; Chen, Qing; Darmohusodo, Vincent; Dean, Aaron R., Comestible compositions comprising high potency savory flavorants, and processes for producing them.
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  167. Gerna, Giuseppe; Sarasini, Antonella; Revello, Maria Grazia, Compositions and methods for human metapneumovirus monoclonal antibodies.
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  168. Weise, Dale Wade; Harris, James Robert, Compositions and methods for identifying and differentiating viral components of multivalent shipping fever vaccines.
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  169. Bennetzen, Jeffrey L.; Nagy, Ervin D., Compositions and methods for identifying genetic sequences with toxin resistance in plants.
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  170. Manalili Wheeler, Sherilynn; Hannis, James C.; Hofstadler, Steven A., Compositions and methods for inhibiting terminal transferase activity.
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  172. Prakash, Thazha P.; Seth, Punit P.; Swayze, Eric E., Compositions and methods for modulating HBV expression.
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  176. Shahabi, Vafa; Wallecha, Anu; Maciag, Paulo C.; Paterson, Yvonne; Seavey, Matthew, Compositions and methods for prevention of escape mutation in the treatment of HER2/NEU over-expressing tumors.
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  180. Hoge, Stephen G.; de Fougerolles, Antonin; Ellsworth, Jeff Lynn, Compositions and methods of altering cholesterol levels.
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  181. Kirkland, III, Theo N.; Viriyakosol, Sunganya, Compositions and methods using MD-2 mutants and chimeric proteins.
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  182. Paterson, Yvonne; Maciag, Paulo; Ferrone, Soldano, Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof.
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  184. Allerson, Charles; Bhat, Balkrishen; Eldrup, Anne B.; Manoharan, Muthiah; Griffey, Richard H.; Baker, Brenda F.; Swayze, Eric E., Compositions comprising alternating 2'-modified nucleosides for use in gene modulation.
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  186. Seavey, Matthew; Paterson, Yvonne; Maciag, Paulo; Sewell, Duane, Compositions comprising angiogenic factors and methods of use thereof.
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  187. Kurn, Nurith, Compositions for amplification of RNA sequences using composite primers.
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  188. Singh, Sharat; Salimi-Moosavi, Hossein; Tahir, Syed Hasan; Wallweber, Gerald J.; Kirakossian, Hrair; Matray, Tracy J.; Hernandez, Vincent S., Compositions for analyzing proteins.
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  189. Kahre, Olev; Artma, Kadri; Kahre, Tiina, Compositions for increasing polypeptide stability and activity, and related methods.
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  190. Kaye, Edward M., Compositions for treating muscular dystrophy.
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  191. Bhanot, Sanjay; Geary, Richard S.; McKay, Robert; Monia, Brett P.; Seth, Punit P.; Siwkowski, Andrew M.; Swayze, Eric E.; Wancewicz, Edward, Compounds and methods for modulating expression ApoB.
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  192. Bhanot, Sanjay; Geary, Richard S.; McKay, Robert; Monia, Brett P.; Seth, Punit P.; Siwkowski, Andrew M.; Swayze, Eric E.; Wancewicz, Edward, Compounds and methods for modulating expression of DGAT2.
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  193. Bhanot, Sanjay; Geary, Richard; McKay, Robert; Monia, Brett P.; Seth, Punit P.; Siwkowski, Andrew M.; Swayze, Eric E.; Wancewicz, Edward, Compounds and methods for modulating expression of GCCR.
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  194. Bhanot, Sanjay; Geary, Richard S.; McKay, Robert; Monia, Brett P.; Seth, Punit P.; Siwkowski, Andrew M.; Swayze, Eric E.; Wancewicz, Edward, Compounds and methods for modulating expression of GCGR.
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  195. Bhanot, Sanjay; Geary, Richard S.; McKay, Robert; Monia, Brett P.; Seth, Punit P.; Siwkowski, Andrew M.; Swayze, Eric E.; Wancewicz, Edward, Compounds and methods for modulating expression of SGLT2.
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  196. Bhat, Balkrishen; Xia, Jie; Seth, Punit P.; Vasquez, Guillermo; Migawa, Michael T.; Allerson, Charles; Prakash, Thazha P.; Swayze, Eric E., Compounds and methods for synthesis of bicyclic nucleic acid analogs.
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  197. Capaldi,Daniel C.; Gaus,Hans Joachim Josef; Rentel,Claus Andre Frank; Olsen,Philip Dmitri; Kurata,Christine C.; Song,Quanlai, Compounds and methods for the characterization of oligonucleotides.
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  198. Richard H. Griffey ; Douglas L. Cole ; Vasulinga Ravikumar, Compounds for the Synthesis of Nucleotide or oligonucleotide phosphoramidites.
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  199. Richard H. Griffey ; Douglas L. Cole ; Vasulinga Ravikumar, Compounds for the synthesis of nucleotide or oligonucleotide phosphoramidites.
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  200. Manoharan Muthiah ; Maier Martin A., Compounds, processes and intermediates for synthesis of mixed backbone oligomeric compounds.
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  201. Muthiah Manoharan ; Martin A. Maier, Compounds, processes and intermediates for synthesis of mixed backbone oligomeric compounds.
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  202. Bennett, C. Frank; McKay, Robert; Monia, Brett P.; Baker, Brenda F.; Sioufi, Namir, Conjugates for use in hepatocyte free uptake assays.
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  203. Emrich, Thomas; Haberhausen, Gerd; Moczko, Martin, Control for nucleic acid testing.
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  204. Farokhzad, Omid C.; Jon, Sang Yong; Langer, Robert S., Controlled release nanoparticle having bound oligonucleotide for targeted delivery.
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  206. Santhanam, Uma; Kyrou, Christos D.; Mazich, Desiree; Hong, Qi; Shaheen, Hussam H., Cosmetic uses of modified stressed yeast extracts and related compositions.
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  207. Verthelyi, Daniela; Beaucage, Serge L.; Grajkowski, Andrzej, CpG oligonucleotide prodrugs, compositions thereof and associated therapeutic methods.
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  208. Christopher P. Holmes, Cyclic and substituted immobilized molecular synthesis.
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  209. Wood, Bradford J.; Dreher, Matthew; Negussie, Ayele H., Cyclized NGR peptide compounds, compositions, and methods of their use.
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  210. Seth, Punit P.; Swayze, Eric E., Cyclohexenyl nucleic acids analogs.
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  211. Seth, Punit P.; Swayze, Eric E., Cyclohexenyl nucleic acids analogs.
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  212. de Fougerolles, Antonin; Wood, Kristy M.; Elbashir, Sayda M.; Schrum, Jason P., DLIN-KC2-DMA lipid nanoparticle delivery of modified polynucleotides.
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  213. Brandis, John; Bloom, Curtis; Richards, John H., DNA polymerases having improved labeled nucleotide incorporation properties.
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  214. Eshoo, Mark W., DNA sequencing.
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  215. Pastan, Ira H.; Weldon, John; FitzGerald, David, Deletions in domain II of pseudomonas exotoxin a that remove immunogenic epitopes.
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  218. Ravikumar, Vasulinga, Deprotection of phosphorus in oligonucleotide synthesis.
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  219. Walter, Nils; Johnson-Buck, Alexander; Blanco, Mario; Rinaldi, Arlie, Detection of nucleic acids.
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  220. Ozbal, Can C.; Jonas, Maxine; LaMarr, William A.; Vernikov, Eduard, Devices and methods for coupling mass spectrometry devices with chromatography systems.
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  221. Gerna, Giuseppe; Sarasini, Antonella; Revello, Maria Grazia, Devices and methods for detecting human metapneumovirus.
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  222. Ngo, Nam; Jaquinod, Laurent; Wang, Hong, Devices and methods for the synthesis of nucleic acids.
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  223. Chang, Sherman H., Diagnosis of melanoma and solar lentigo by nucleic acid analysis.
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  224. Gordon, Gavin J.; Bueno, Raphael, Diagnostic tests using gene expression ratios.
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  225. Ahlquist, David A.; Taylor, William R.; Zou, Hongzhi; Lidgard, Graham P., Digital sequence analysis of DNA methylation.
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  227. Cole, Douglas L.; Ravikumar, Vasulinga, Diribonucleoside Phosphoramidites.
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  228. Hofstede, René Johannes Maria; De Ruiter, Wouter Pieter Johannes, Disease resistant cucumber plants.
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  229. Baker, Brenda F.; Kraynack, Bryan A., Double stranded constructs comprising one or more short strands hybridized to a longer strand.
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  230. Woolf, Tod, Double-stranded oligonucleotides.
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  231. Woolf, Tod; Wiederholt, Kristin, Double-stranded oligonucleotides.
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  233. Dodo, Hortense W.; Arntzen, Charles J.; Viquez, Olga Martha; Konan, Koffi N'da, Down-regulation and silencing of allergen genes in transgenic peanut seeds.
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  236. Maciag, Paulo; Wallecha, Anu; Shahabi, Vafa, Dual delivery system for heterologous antigens.
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  237. Rose, Scott D.; Walder, Joseph A.; Beltz, Kristin; Allen, Shawn, Efficient and rapid method for assembling and cloning double-stranded DNA fragments.
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  238. Stemmer Willem P. C. ; Lipshutz Robert J., End-complementary polymerase reaction.
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  239. Stemmer Willem Peter Christiaan ; Lipshutz Robert J., End-complementary polymerase reaction.
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  240. Willem P.C. Stemmer ; Robert J. Lipshutz, End-complementary polymerase reaction.
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  241. Bancel, Stephane; Schrum, Jason P.; Aristarkhov, Alexander, Engineered nucleic acids and methods of use thereof.
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  243. Schrum, Jason P.; Bancel, Stephane; Afeyan, Noubar B., Engineered nucleic acids and methods of use thereof.
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  246. Schrum, Jason P.; Bancel, Stéphane; Afeyan, Noubar B., Engineered nucleic acids and methods of use thereof.
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  247. Schrum, Jason P.; Sieczkiewicz, Gregory J.; Ejebe, Kenechi; Elbashir, Sayda M., Engineered nucleic acids and methods of use thereof.
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  248. Schrum, Jason P.; Afeyan, Noubar B.; Sieczkiewicz, Gregory J.; Bancel, Stephane; de Fougerolles, Antonin; Elbashir, Sayda M., Engineered nucleic acids encoding a modified erythropoietin and their expression.
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  249. Blake, William Jeremy; Cunningham, Drew S., Engineered phosphoglucose isomerase proteins with a protease cleavage site.
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  250. Froehler Brian ; Jones Robert J., Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines.
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  251. Froehler Brian (Belmont CA) Matteucci Mark (Burlingame CA), Enhanced triple-helix and double-helix formation with oligomers containing modified purines.
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  252. Brian Froehler ; Rick Wagner ; Mark Mattencci ; Robert J. Jones ; Arnold J. Gutierrez ; Jeff Pudlo, Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines.
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  253. Froehler, Brian; Wagner, Rick; Matteucci, Mark; Jones, Robert J.; Gutierrez, Arnold J.; Pudlo, Jeff, Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines.
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  254. Froehler, Brian; Wagner, Rick; Matteucci, Mark; Jones, Robert J.; Gutierrez, Arnold J.; Pudlo, Jeff, Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines.
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  255. Froehler,Brian; Wagner,Rick; Mattencci,Mark; Jones,Robert J.; Gutierrez,Arnold J.; Pudlo,Jeff, Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines.
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  256. Makrigiorgos, Gerassimos, Enrichment of a target sequence.
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  257. Berahovich, Robert D.; Miao, Zhenhua; Premack, Brett; Schall, Thomas J., Enzymatic activities in chemokine-mediated inflammation.
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  258. Bott Richard Ray ; Caldwell Robert Mark ; Cunningham Brian C. ; Estell David Aaron ; Power Scott Douglas ; Wells James Allen, Enzymatically active modified subtilisins.
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  259. Bestwick, Richard K.; Frank, Diane Elizabeth, Exon skipping compositions for treating muscular dystrophy.
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  260. David J. Lockhart ; Eugene L. Brown ; Gordon G. Wong ; Mark S. Chee ; Thomas R. Gingeras, Expression monitoring by hybridization to high density nucleic acid arrays.
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  261. Lockhart, David J.; Brown, Eugene L.; Wong, Gordon G.; Chee, Mark; Gingeras, Thomas R., Expression monitoring by hybridization to high density oligonucleotide arrays.
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  262. Tachdjian, Catherine; Patron, Andrew P.; Adamski-Werner, Sara L.; Bakir, Farid; Chen, Qing; Darmohusodo, Vincent; Hobson, Stephen Terrence; Li, Xiaodong; Qi, Ming; Rogers, Daniel H.; Rinnova, Marketa; Servant, Guy; Tang, Xiao-Qing; Zoller, Mark; Wallace, David; Xing, Amy; Gubernator, Klaus, Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof.
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  263. Tachdjian, Catherine; Patron, Andrew P.; Adamski-Werner, Sara L.; Bakir, Farid; Chen, Qing; Darmohusodo, Vincent; Hobson, Stephen Terrence; Li, Xiaodong; Qi, Ming; Rogers, Daniel H.; Rinnova, Marketa; Servant, Guy; Tang, Xiao-Qing; Zoller, Mark; Wallace, David; Xing, Amy; Gubernator, Klaus, Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof.
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  264. Williams, John G. K.; Bashford, Gregory R; Chen, Jiyan; Draney, Dan; Narayanan, Nara; Reynolds, Bambi L.; Sheaff, Pamela, Flowcell systems for single molecule detection.
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  265. Taing, Meng C.; Khan, Shaheer H.; Menchen, Steven M.; Rosenblum, Barnett B., Fluorescent nucleobase conjugates having anionic linkers.
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  266. Li, Wan-Liang Robert; Zhou, Jian S., Fluorescent oligonucleotides and uses thereof.
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  267. de Fougerolles, Antonin; Wood, Kristy M.; Valencia, Pedro, Formulation and delivery of PLGA microspheres.
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  268. de Fougerolles, Antonin; Wood, Kristy M.; Valencia, Pedro, Formulation and delivery of PLGA microspheres.
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  269. Makrigiorgos, Gerassimos, Full COLD-PCR enrichment with reference blocking sequence.
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  270. Sanghvi, Yogesh S.; Manoharan, Muthiah, Gapped oligomers having site specific chiral phosphorothioate internucleoside linkages.
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  271. Kurn, Nurith; Wang, Shenglong, Global amplification using a randomly primed composite primer.
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  272. Kurn, Nurith; Wang, Shenglong, Global amplification using a randomly primed composite primer.
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  273. Manoharan, Muthiah; Cook, Phillip Dan; Prakash, Thazha P.; Mohan, Venkatraman, Guanidinium functionalized intermediates.
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  274. Manoharan, Muthiah; Cook, Phillip Dan; Prakash, Thazha P.; Mohan, Venkatraman, Guanidinium functionalized nucleotides and precursors thereof.
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  275. Manoharan, Muthiah; Cook, Phillip Dan; Prakash, Thazha P.; Mohan, Venkatraman, Guanidinium functionalized oligonucleotides and method/synthesis.
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  276. Cha Tai-An ; Beall Eileen ; Irvine Bruce ; Kolberg Janice ; Urdea Michael S., HCV genomic sequences for diagnostics and therapeutics.
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  277. Cha Tai-An ; Beall Eileen ; Irvine Bruce ; Kolberg Janice ; Urdea Michael S., HCV genomic sequences for diagnostics and therapeutics.
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  278. Cha Tai-An ; Beall Eileen ; Irvine Bruce ; Kolberg Janice ; Urdea Michael S., HCV genomic sequences for diagnostics and therapeutics.
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  279. Cha Tai-An ; Beall Eileen ; Irvine Bruce ; Kolberg Janice ; Urdea Michael S., HCV genomic sequences for diagnostics and therapeutics.
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  280. Leckie, Gregor W.; Ofsaiof, Reuben J.; Vijesurier, Roy M.; Wang, Hong, Hepatitis B virus typing and resistance assay.
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  281. Williams John G. K., Heterogeneous assay for pyrophosphate.
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  282. Williams John G. K., Heterogeneous assay for pyrophosphate detection.
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  283. Brown, David; Ford, Lance P.; Jarvis, Richard A.; Pallotta, Vince; Pasloske, Brittan L., High potency siRNAS for reducing the expression of target genes.
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  284. Ozbal, Can; Green, Donald, High throughput autosampler.
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  285. Kokoris, Mark Stamatios; McRuer, Robert N., High throughput nucleic acid sequencing by expansion.
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  286. Kokoris, Mark Stamatios; McRuer, Robert N., High throughput nucleic acid sequencing by expansion.
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  287. Kokoris, Mark Stamatios; McRuer, Robert N., High throughput nucleic acid sequencing by expansion.
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  288. Ellis, Ronald; Tal, Michael; Samira, Sarit; Rachamim, Nurit; Jones, Timothy David; Carr, Francis Joseph; Dotan, Shahar, Humanized antibodies to cluster of differentiation 3 (CD3).
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  289. Hedgpeth Joel ; Afonina Irina A. ; Kutyavin Igor V. ; Lukhtanov Eugeny A. ; Belousov Evgeniy S. ; Meyer ; Jr. Rich B., Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders.
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  290. Hedgpeth, Joel; Afonina, Irina A.; Kutyavin, Igor V.; Lukhtanov, Eugeny A.; Belousov, Evgeniy S.; Meyer, Jr., Rich B., Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders.
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  291. Hedgpeth, Joel; Afonina, Irina A.; Kutyavin, Igor V.; Lukhtanov, Eugeny A.; Belousov, Evgeniy S.; Meyer, Jr., Rich B., Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders.
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  349. Rothman, John; Wallecha, Anu; Singh, Reshma; Harn, Jr., Donald A.; Paterson, Yvonne, Listeria-based adjuvants.
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  351. Hessel, Edith M.; Coffman, Robert L., Long term disease modification using immunostimulatory oligonucleotides.
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  354. Bergmann, Frank; Von Der Eltz, Herbert; Seidel, Christoph; Weindel, Kurt, Mannitol and glucitol derivatives.
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  355. Yu, Ju-Kyung; Bowers, Glenn; Breitinger, Becky Welsh; Chakraborty, Nanda, Markers associated with soybean rust resistance and methods of use therefor.
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  362. Koester Hubert (Concord MA) Coull James M. (Acton MA), Membranes with bound oligonucleotides and peptides.
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  363. Piomelli, Daniele; Moreno-Sanz, Guillermo; Bandiera, Tiziano; Mor, Marco; Tarzia, Giorgio, Meta-substituted biphenyl peripherally restricted FAAH inhibitors.
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  365. Leproust,Eric M.; Reddy,Lalitha; Perbost,Michel G M, Method and apparatus for microarray fabrication.
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  366. Fodor Stephen P. A. ; Solas Dennis W. ; Dower William J., Method for comparing copy number of nucleic acid sequences.
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  367. Kumagai Monto H. ; della-Cioppa Guy R., Method for conferring herbicide, pest, or disease resistance in plant hosts.
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  368. Gebeyehu, Gulilat; Pires, Richard, Method for deblocking of labeled oligonucleotides.
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  369. Gebeyehu, Gulilat; Pires, Richard, Method for deblocking of labeled oligonucleotides.
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  370. Gebeyehu, Gulilat; Pires, Richard M, Method for deblocking of labeled oligonucleotides.
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  371. Gebeyehu, Gulilat; Pires, Richard M., Method for deblocking of labeled oligonucleotides.
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  372. Korth Kevin Gary ; Heathcock Sarah Elizabeth ; Huard Linda Susan, Method for detection of Pseudomonas aeruginosa using polymerase chain reaction.
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  373. Murphy, Patricia D., Method for determining the haplotype of a human BRCA1 gene.
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  374. Pieken,Wolfgang; Wolter,Andreas; Sebesta,David P.; Leuck,Michael; Latham Timmons,Hallie A.; Pilon,John; Husar,Gregory M., Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method.
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  375. English, James T.; Schmidt, Francis J.; Stacey, Gary; Fang, Zhiwei, Method for inducing resistance to fungal infection in transgenic plants using plant defense peptides.
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  376. English, James T.; Schmidt, Francis J.; Stacey, Gary; Fang, Zhiwei, Method for inducing resistance to fungal infection in transgenic plants using plant defense peptides.
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  377. Fodor, Stephen P. A.; Solas, Dennis W.; Dower, William J., Method for marking samples.
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  378. Woo Sam L. (Redwood City CA) Fung Steven (Palo Alto CA), Method for preparing 3′-nitrogen containing polynucleotides.
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  379. Adamo, Ilaria; Dueymes, Cecile; Schonberger, Andreas; Imbach, Jean-Louis; Meyer, Albert; Morvan, Francois; Debart, Francoise; Vasseur, Jean-Jacques; Lange, Meinolf; Link, Fritz, Method for preparing oligonucleotides.
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  380. de Fougerolles, Antonin; Wood, Kristy M.; Elbashir, Sayda M.; Schrum, Jason P., Method for producing a protein of interest in a primate.
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  381. Chreng, Dana, Method for solution phase detritylation of oligomeric compounds.
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  382. Pieken Wolfgang ; McGee Danny ; Settle Alecia ; Zhai Yansheng ; Huang Jianping, Method for solution phase synthesis of oligonucleotides.
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  383. Migawa, Michael T.; Yu, Jinghua; Wan, W. Brad; Patel, Satyen P.; Vasquez, Guillermo; Kinberger, Garth A.; Prakash, Thazha P.; Seth, Punit P.; Swayze, Eric E., Method for synthesis of reactive conjugate clusters.
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  386. Huletsky, Ann; Rossbach, Valery, Method for the detection and identification of methicillin-resistant Staphylococcus aureus.
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  387. Jaeger,Stephan, Method for the determination of a nucleic acid using a control.
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  388. Jaeger,Stephan, Method for the determination of a nucleic acid using a control.
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  389. Jaeger,Stephan, Method for the determination of a nucleic acid using a control.
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  390. Patterson, William, Method for the selection of specific affinity binders by homogeneous noncompetitive assay.
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  391. Patterson, William, Method for the selection of specific affinity binders by homogeneous noncompetitive assay.
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  392. Patterson, William, Method for the selection of specific affinity binders by homogeneous noncompetitive assay.
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  393. Griffey Richard H. ; Cole Douglas L. ; Ravikumar Vasulinga, Method for the synthesis of nucleotide or oligonucleotide phosphoramidites.
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  394. Griffey Richard H. ; Cole Douglas L. ; Ravikumar Vasulinga T., Method for the synthesis of nucleotide or oligonucleotide phosphoramidites.
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  395. Wada, Takeshi; Shimizu, Mamoru, Method for the synthesis of phosphorus atom modified nucleic acids.
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  396. Wada, Takeshi; Shimizu, Mamoru, Method for the synthesis of phosphorus atom modified nucleic acids.
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  397. Fodor, Stephen P. A.; Solas, Dennis W.; Dower, William J., Method of comparing nucleic acid sequences.
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  398. Monto H. Kumagai ; Guy R. della-Cioppa ; Robert L. Erwin ; David R. McGee, Method of compiling a functional gene profile in a plant by transfecting a nucleic acid sequence of a donor plant into a different host plant in an anti-sense orientation.
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  399. Zaffaroni Alejandro C. ; Buchko Christopher J. ; Modlin Douglas N., Method of conducting a plurality of reactions.
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  400. Fung Steven (Palo Alto CA) Woo Sam L. (Redwood City CA) Haugland Richard P. (Junction City OR) Menchen Steven M. (Hayward CA) Connell Charles R. (Redwood City CA), Method of detecting electrophoretically separated oligonucleotides.
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  401. Hoffmann, Bernd; Depner, Klaus; Beer, Martin, Method of detection of classical swine fever.
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  403. Cedillo, Isaiah E.; Janczak, Darren; Weaver, Phillip Michael, Method of preparing oligomeric compounds using modified capping protocols.
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  409. Ford, Lance P.; Krebs, Joseph, Methods and compositions concerning siRNA's as mediators of RNA interference.
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  410. Kim, Sung K.; Deciu, Cosmin, Methods and compositions for analyzing nucleic acid.
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  413. Kutyavin, Igor, Methods and compositions for detection of nucleic acids based on stabilized oligonucleotide probe complexes.
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  415. Kurn, Nurith, Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof.
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  418. Eberwine, James; Langel, Ulo; Kilk, Kalle; Zielinski, Jennifer, Methods and compositions for identifying RNA-binding proteins.
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  419. Paterson, Yvonne; Singh, Reshma, Methods and compositions for immunotherapy of cancer.
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  420. Barrat, Franck; Coffman, Robert L.; Matray, Tracy; Guiducci, Cristiana, Methods and compositions for inhibition of immune responses and autoimmunity.
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  422. Barrat, Franck; Coffman, Robert L., Methods and compositions for inhibition of innate immune responses and autoimmunity.
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  423. Chesnut, Jonathan; Dudas, Miroslav; Harris, Adam; Leong, Louis; Madden, Knut, Methods and compositions for seamless cloning of nucleic acid molecules.
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  427. Arar, Khalil, Methods and compositions for the tandem synthesis of two or more oligonucleotides on the same solid support.
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  428. Kurn, Nurith, Methods and compositions for transcription-based nucleic acid amplification.
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  429. Summar, Marshall L.; Barr, Frederick E.; Thompson, Reid Carleton, Methods and compositions for treatment for coronary and arterial aneurysmal subarachnoid hemorrhage.
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  430. Spies, Thomas; Spies, Veronika, Methods and compositions involving NKG2D inhibitors and cancer.
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  431. Garcia, Joe G. N., Methods and compositions involving PBEF inhibitors for lung inflammation conditions and diseases.
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  432. Abbaszadegan Morteza ; Di Giovanni George Dominic ; LeChevallier Mark William, Methods and kits for detection of Cryptosporidium parvum using immunomagnetic separation and amplification.
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  433. Morteza Abbaszadegan ; George Dominic Di Giovanni ; Mark William LeChevallier, Methods and kits for detection of cryptosporidium parvum.
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  434. Montagnier, Luc; Skorupka, Corinne; Raymond, Phillipe; Bottero, Philippe, Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders.
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  435. Kurn, Nurith, Methods and probes for detection and/or quantification of nucleic acid sequences.
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  436. Cantor, Charles R.; DeSantis, Grace; Mueller, Reinhold; Ehrich, Mathias, Methods and processes for non-invasive assessment of genetic variations.
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  438. Gamble Ronald C. ; Theriault Thomas P. ; Winder Scott C., Methods and solvent vehicles for reagent delivery in oligonucleotide synthesis using automated pulse jetting devices.
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  439. Zhou, Wei; Mei, Rui; Crnogorac, Filip; Liao, Guochun; Lucas, Julian, Methods and systems for sequencing long nucleic acids.
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  441. Jewett, Michael C.; Hodgman, Charles E.; Gan, Rui, Methods for cell-free protein synthesis.
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  442. Paterson, Yvonne; Verch, Thorsten, Methods for constructing antibiotic resistance free vaccines.
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  445. Klein-Marcuschamer, Daniel, Methods for control of flux in metabolic pathways.
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  449. Gerna, Giuseppe; Sarasini, Antonella; Revello, Maria Grazia, Methods for detecting human metapneumovirus.
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  453. Moser, Michael James, Methods for detection and typing of nucleic acids.
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  454. Moser, Michael James, Methods for detection and typing of nucleic acids.
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  455. Moser, Michael James, Methods for detection and typing of nucleic acids.
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  456. Sorge,Joseph A.; Whalen,Anne M., Methods for detection of a target nucleic acid by capture.
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  458. Sorge, Joseph A., Methods for detection of a target nucleic acid by forming a cleavage structure with a cleavage resistant probe.
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  459. Sorge, Joseph A., Methods for detection of a target nucleic acid sequence.
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  460. Hunter, Ian; Brenan, Colin J. H.; Kanigan, Tanya S., Methods for filing a sample array by droplet dragging.
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  461. Petersdorf, Effie W.; Guo, Zhen; Hood, Leroy, Methods for haplotyping genomic DNA.
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  462. Petersdorf, Effie W.; Guo, Zhen; Hood, Leroy, Methods for haplotyping genomic DNA.
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  463. Petersdorf,Effie W.; Guo,Zhen; Hood,Leroy, Methods for haplotyping genomic DNA.
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  464. Jewett, Michael Christopher; Fritz, Brian Robert; Timmerman, Laura Elyse; Liu, Yi, Methods for making ribosomes.
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  465. Glahn et al., Methods for measuring relative amounts of nucleic acids in a complex mixture and retrieval of specific sequences therefrom.
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  466. Gildea, Brian D.; Coull, James M., Methods for modulating the solubility of synthetic polymers.
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  467. Goldberg, Martin J.; Diggelman, Martin; Hubbell, Earl A.; McGall, Glenn H.; Ngo, Nam Quoc; Morris, MacDonald; Yamamoto, Melvin; Tan, Jennifer; Rava, Richard P., Methods for photolithographic synthesis of polymer arrays utilizing anti-reflective coatings.
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  468. Stryer, Lubert; Fodor, Stephen P. A.; Read, J. Leighton; Pirrung, Michael C., Methods for polymer synthesis.
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  469. Achim H. Krotz ; Bethany M. McElroy ; Anthony N. Scozzari, Methods for removing dimethoxytrityl groups from oligonucleotides.
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  470. Krotz, Achim H.; McElroy, Bethany M.; Scozzari, Anthony N., Methods for removing dimethoxytrityl groups from oligonucleotides.
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  471. Rovera Giovanni ; Mukhopadhyay Sunil, Methods for solid-phase amplification of DNA template (SPADT) using multiarrays.
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  472. Krotz,Achim H.; Ravikumar,Vasulinga T., Methods for synthesis of oligonucleotides.
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  473. Lippe, Catherine; Duteaud, Isabelle; Roger-Dalbert, Celine, Methods for the detection and identification of extended spectrum beta lactamases.
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  474. Delagrave, Simon; Marrs, Barry, Methods for the enzymatic assembly of polynucleotides and identification of polynucleotides having desired characteristics.
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  475. Pieken,Wolfgang; Wolter,Andreas; Leuck,Michael, Methods for the integrated synthesis and purification of oligonucleotides.
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  476. Muthiah Manoharan, Methods for the preparation of conjugated oligomers.
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  477. Verdine, Gregory L.; Meena; Iwamoto, Naoki; Butler, David Charles Donnell, Methods for the synthesis of functionalized nucleic acids.
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  478. Kurn, Nurith, Methods of RNA amplification in the presence of DNA.
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  479. Van Nest,Gary, Methods of ameliorating symptoms of herpes infection using immunomodulatory polynucleotide sequences.
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  480. Sorge, Joseph A., Methods of detecting an amplified nucleic acid.
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  481. Lockhart, David J.; Chee, Mark S.; Digglemann, Martin; Vetter, Dirk, Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA.
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  482. Lockhart, David J.; Brown, Eugene L.; Wong, Gordon G.; Chee, Mark; Gingeras, Thomas R., Methods of identifying nucleic acid probes to quantify the expression of a target nucleic acid.
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  483. Stuelpnagel,John; Chee,Mark; Auger,Steven, Methods of making and using composite arrays for the detection of a plurality of target analytes.
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  484. Fodor, Stephen P. A.; Stryer, Lubert; Read, J. Leighton; Pirrung, Michael C., Methods of making nucleic acid or oligonucleotide arrays.
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  485. Van Nest, Gary; Tuck, Stephen F.; Eiden, Jr., Joseph, Methods of modulating an immune response using immunostimulatory sequences and compositions for use therein.
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  486. Van Nest,Gary; Tuck,Stephen; Eiden, Jr.,Joseph, Methods of modulating an immune response using immunostimulatory sequences and compositions for use therein.
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  487. Van Nest, Gary, Methods of preventing and treating respiratory viral infection using immunomodulatory polynucleotide sequences.
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  488. Van Nest, Gary; Eden, Jr., Joseph J., Methods of suppressing hepatitis virus infection using immunomodulatory polynucleotide sequences.
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  489. Stryer, Lubert; Pirrung, Michael C.; Read, J. Leighton; Fodor, Stephen P. A., Methods of synthesizing a plurality of different polymers on a surface of a substrate.
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  490. Zhou, Wei; Mei, Rui; Matsuzaki, Hajime, Methods of targeted sequencing.
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  491. Ashley, Euan A.; Perez, Marco V., Methods of treating heart failure with agonists of hypocretin receptor 2.
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  492. Barrat, Franck; Coffman, Robert L.; Guiducci, Cristiana, Methods of treatment using TLR7 and/or TLR9 inhibitors.
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  494. Froehler Brian ; Wagner Rick ; Matteucci Mark ; Jones Robert J. ; Gutierrez Arnold J. ; Pudlo Jeff, Methods of using oligomers containing modified pyrimidines.
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  495. Wronska, Danuta; Journigan, Terri W; Mellott, James D, Methods, compositions, and kits for determining human immunodeficiency virus (HIV).
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  496. Kurn, Nurith, Methods, kits and compositions for single primer linear isothermal amplification of nucleic acid sequences.
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  497. Nakagawara, Akira; Ohira, Miki; Ishii, Shin; Goto, Takeshi; Kubo, Hiroyuki; Hirata, Takahiro; Yoshida, Yasuko; Yamada, Saichi, Microarray for predicting the prognosis of neuroblastoma and method for predicting the prognosis of neuroblastoma.
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  498. Hasan, Leila; Linton, John; Brenan, Colin J. H., Microfluidic transfer pin.
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  499. Hasan, Leila; Linton, John; Brenan, Colin J. H., Microfluidic transfer pin.
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  500. Ryan T., Gill; Lynch, Michael D.; Lipscomb, Tanya E. W., Mixed library parallel gene mapping quantitative micro-array technique for genome-wide identification of trait conferring genes.
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  501. Gill, Ryan T.; Lynch, Michael D.; Warnecke, Tanya, Mixed-library parallel gene mapping quantitative micro-array technique for genome-wide identification of trait conferring genes.
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  502. Prakash, Thazha P.; Seth, Punit P.; Manoharan, Muthiah; Swayze, Eric E.; Rajeev, Kallanthottathil G.; Zlatev, Ivan, Modified 5′ diphosphate nucleosides and oligomeric compounds prepared therefrom.
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  503. Vermaas, Willem F. J., Modified cyanobacteria.
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  506. Schrum, Jason P.; Siddiqi, Suhaib; Ejebe, Kenechi, Modified nucleosides, nucleotides, and nucleic acids, and uses thereof.
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  509. de Fougerolles, Antonin; Roy, Atanu; Schrum, Jason P.; Siddiqi, Suhaib; Hatala, Paul; Bancel, Stephane, Modified nucleosides, nucleotides, and nucleic acids, and uses thereof.
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  510. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides encoding SIAH E3 ubiquitin protein ligase 1.
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  511. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides encoding apoptosis inducing factor 1.
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  512. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides encoding aquaporin-5.
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  513. Chakraborty, Tirtha; de Fougerolles, Antonin; Weiss, Ron, Modified polynucleotides encoding aryl hydrocarbon receptor nuclear translocator.
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  514. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides encoding basic helix-loop-helix family member E41.
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  515. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides encoding citeD4.
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  516. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides encoding copper metabolism (MURR1) domain containing 1.
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  517. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides encoding granulysin.
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  518. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Whoriskey, Susan; Weiss, Ron, Modified polynucleotides encoding hepatitis A virus cellular receptor 2.
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  519. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides encoding septin-4.
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  520. de Fougerolles, Antonin; Wood, Kristy M.; Elbashir, Sayda M.; Schrum, Jason P., Modified polynucleotides for the production of G-CSF.
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  521. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin, Modified polynucleotides for the production of biologics and proteins associated with human disease.
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  522. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin, Modified polynucleotides for the production of biologics and proteins associated with human disease.
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  523. Bancel, Stephane; Huang, Eric Yi-Chun, Modified polynucleotides for the production of cosmetic proteins and peptides.
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  524. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin, Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins.
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  525. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins.
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  526. Chakraborty, Tirtha; de Fougerolles, Antonin; Weiss, Ron, Modified polynucleotides for the production of nuclear proteins.
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  527. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin, Modified polynucleotides for the production of oncology-related proteins and peptides.
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  528. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; Ellsworth, Jeff Lynn; Ejebe, Kenechi; Guild, Justin; John, Matthias; Hatala, Paul; Roy, Atanu; Schrum, Jason P.; Whoriskey, Susan; Wood, Kristy M., Modified polynucleotides for the production of proteins.
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  529. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin, Modified polynucleotides for the production of proteins.
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  530. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides for the production of proteins associated with blood and lymphatic disorders.
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  531. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides for the production of proteins associated with blood and lymphatic disorders.
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  532. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin, Modified polynucleotides for the production of proteins associated with human disease.
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  533. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin, Modified polynucleotides for the production of secreted proteins.
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  534. Chakraborty, Tirtha; de Fougerolles, Antonin, Modified polynucleotides for the production of secreted proteins.
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  535. Chakraborty, Tirtha; de Fougerolles, Antonin; Weiss, Ron, Modified polynucleotides for treating galactosylceramidase protein deficiency.
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  536. Chakraborty, Tirtha; de Fougerolles, Antonin; Weiss, Ron, Modified polynucleotides for treating protein deficiency.
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  537. Bott Richard Ray ; Caldwell Robert Mark ; Cunningham Brian C. ; Estell David Aaron ; Power Scott Douglas ; Wells James Allen, Modified subtilisins having amino acid alterations.
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  538. Bott Richard Ray ; Caldwell Robert Mark ; Cunningham Brian C. ; Estell David Aaron ; Power Scott Douglas ; Wells James Allen, Modified subtilisins having amino acid alterations.
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  539. Bott Richard Ray ; Caldwell Robert Mark ; Cunningham Brian C. ; Estell David Aaron ; Power Scott Douglas ; Wells James Allen, Modified subtilisins having amino acid alterations.
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  540. Van Vuuren, Hendrik Jurgens Jansen; Lonvaud, Aline; Coulon, Joana; Inglis, Debra, Modulating urea degradation in wine yeast.
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  541. Rusconi, Christopher P., Modulators of coagulation factors with enhanced stability.
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  542. Meda, Anderson Rotter; Breitinger, Becky Welsh, Molecular markers linked to disease resistance in soybean.
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  543. Van Gelder,Russell N.; Von Zastrow,Mark E.; Barchas,Jack D.; Eberwine,James H., Multi-gene expression profile.
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  544. Van Gelder Russell N. ; Von Zastrow Mark E. ; Barchas Jack D. ; Eberwine James D., Multi-genes expression profile.
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  545. Schellenberger, Volker; Liu, Amy, Multi-through hole testing plate for high throughput screening.
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  546. Schellenberger, Volker; Liu, Amy Deming, Multi-through hole testing plate for high throughput screening.
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  547. McLuen Gary R. ; Hanney Richard J. ; Hugens Daniel W., Multi-well rotary synthesizer.
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  548. McLuen, Gary R.; Hanney, Richard J.; Hugens, Daniel W., Multi-well rotary synthesizer.
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  549. McLuen, Gary R.; Hanney, Richard J.; Hugens, Daniel W., Multi-well rotary synthesizer.
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  550. McLuen, Gary R.; Hanney, Richard J.; Hugens, Daniel W., Multi-well rotary synthesizer.
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  553. McLuen,Gary R.; Hanney,Richard J.; Hugens,Daniel W., Multi-well rotary synthesizer.
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  554. McLuen,Gary R.; Hanney,Richard J.; Hugens,Daniel W., Multi-well rotary synthesizer.
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  555. Sazani, Peter; Kole, Ryszard, Multiple exon skipping compositions for DMD.
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  556. Sazani, Peter; Kole, Ryszard, Multiple exon skipping compositions for DMD.
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  562. Urdea Mickey S. (San Francisco CA) Warner Brian D. (Eau Claire WI), Multiple reactor system and method for polynucleotide synthesis.
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  563. Lafferty,Mike; Tweedy,Charles; Butler,James, Multiplexed systems for nucleic acid sequencing.
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  564. Pastan, Ira H.; Onda, Masanori; Nagata, Satoshi; Fitzgerald, David; Kreitman, Robert; Lee, Byungkook, Mutated Pseudomonas exotoxins with reduced antigenicity.
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  565. Beaucage, Serge L.; Wilk, Andrzej; Grajkowski, Andrzej, N-acylphosphoramidites and their use in oligonucleotide synthesis.
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  566. Prakash, Thazha P.; Bhat, Balkrishin; Swayze, Eric E., N-substituted-aminomethylene bridged bicyclic nucleic acid analogs.
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  567. Kanigan, Tanya S.; Smith, Steve; Linton, John; Hess, Robert; Yoder, Karl; Brenan, Colin John Herbert, Nanoliter array loading.
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  570. Kanigan, Tanya; Smith, Steve; Linton, John; Hess, Robert; Yoder, Karl; Brennan, Colin, Nanoliter array loading.
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  571. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Jozef,BEX ; Laroche Yves Rene n,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick George, Nematode-extracted anticoagulant protein.
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  572. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Jozef,BEX ; Laroche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted anticoagulant protein.
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  573. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Jozef,BEX ; Laroche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted anticoagulant protein.
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  574. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Jozef,BEX ; Laroche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted anticoagulant protein.
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  575. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Jozef,BEX ; Laroche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted anticoagulant protein.
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  576. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Jozef,BEX ; Laroche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted anticoagulant protein.
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  577. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Josef,BEX ; LaRoche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted serine protease inhibitors and anticoagulant proteins.
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  578. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Josef,BEX ; LaRoche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted serine protease inhibitors and anticoagulant proteins.
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  579. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Josef,BEX ; LaRoche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted serine protease inhibitors and anticoagulant proteins.
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  580. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Josef,BEX ; LaRoche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted serine protease inhibitors and anticoagulant proteins.
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  581. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Josef,BEX ; LaRoche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted serine protease inhibitors and anticoagulant proteins.
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  582. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Josef,BEX ; LaRoche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted serine protease inhibitors and anticoagulant proteins.
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  583. Vlasuk George Phillip ; Stanssens Patrick Eric Hugo,BEX ; Messens Joris Hilda Lieven,BEX ; Lauwereys Marc Josef,BEX ; LaRoche Yves Rene,BEX ; Jespers Laurent Stephane,BEX ; Gansemans Yannick Georges , Nematode-extracted serine protease inhibitors and anticoagulant proteins.
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  584. Vlasuk, George Phillip; Stanssens, Patrick Eric Hugo; Messens, Joris Hilda Lieven; Lauwereys, Marc Josef; LaRoche, Yves Rene; Jespers, Laurent Stephane; Gansemans, Yannick Georges Jozef; Moyle, Matth, Nematode-extracted serine protease inhibitors and anticoagulant proteins.
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  585. Vlasuk, George Phillip; Stanssens, Patrick Eric Hugo; Messens, Joris Hilda Lieven; Lauwereys, Marc Josef; LaRoche, Yves Rene; Jespers, Laurent Stephane; Gansemans, Yannick Georges Jozef; Moyle, Matth, Nematode-extracted serine protease inhibitors and anticoagulant proteins.
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  586. Linda G. Lee ; Ronald J. Graham ; Khairuzzaman B. Mullah ; Francis T. Haxo, Non-fluorescent asymmetric cyanine dye compounds useful for quenching reporter dyes.
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  587. Will, Stephen G., Non-fluorescent energy transfer.
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  588. Paterson, Yvonne; Maciag, Paulo Cesar, Non-hemolytic LLO fusion proteins and methods of utilizing same.
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  589. Richard Ray Bott ; Robert Mark Caldwell ; Brian C. Cunningham ; David Aaron Estell ; Scott Douglas Power ; James Allen Wells, Non-human carbonyl hydrolase mutants, DNA sequences and vectors encoding same and hosts transformed with said vectors.
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  590. Kool,Eric Todd, Nonpolar thymidine analogs.
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  591. Erlander, Mark G.; Salunga, Ranelle C., Nucleic acid amplification.
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  593. Kurn, Nurith; Wang, Shenglong, Nucleic acid amplification procedure using RNA and DNA composite primers.
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  595. David J. Lockhart ; Mark Chee ; Kevin Gunderson ; Lai Chaoqiang ; Lisa Wodicka ; Maureen T. Cronin ; Danny Lee ; Huu M. Tran ; Hajime Matsuzaki, Nucleic acid analysis techniques.
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  596. Pirrung Michael C. ; Read J. Leighton ; Fodor Stephen P. A. ; Stryer Lubert, Nucleic acid arrays.
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  597. Hu, A-Li W.; Hartley, James L.; Jordan, Heather J., Nucleic acid ladders.
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  598. Jordan, Heather J., Nucleic acid ladders.
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  599. Chesnut, Jon; Leong, Louis, Nucleic acid molecules containing recombination sites and methods of using the same.
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  601. Verdine, Gregory L.; ., Meena; Iwamoto, Naoki, Nucleic acid prodrugs and methods of use thereof.
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  602. Pirrung, Michael C.; Read, J. Leighton; Fodor, Stephen P. A.; Stryer, Lubert, Nucleic acid reading and analysis system.
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  603. Stephen P. A. Fodor ; J. Leighton Read ; Lubert Stryer ; Michael C. Pirrung, Nucleic acid reading and analysis system.
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  604. Williams, John G. K.; Bashford, Gregory R., Nucleic acid sequencing using charge-switch nucleotides.
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  605. Cracauer, Raymond F.; Skrzypczynski, Zbigniev; Reimer, Ned D.; Ganske, Rocky, Nucleic acid synthesizers.
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  607. Oeth, Paul Andrew; Mahboubi, Payam; Lee, Min Seob, Nucleic acid-based tests for prenatal gender determination.
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  608. Johnson,Robert C.; Mohammed,Mansoor; Kim,Jae Weon; Lu,Xan Yan, Nucleic acids arrays and methods of use therefor.
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  609. Ronald D. Vale ; James J. Hartman, Nucleic acids encoding a katanin p60 subunit.
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  610. Froehler, Brian C.; Buhr, Chris A., Nucleoside hydrogen phosphonodithioate diesters and activated phosphonodithioate analogues.
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  611. Caruthers Marvin H. (Boulder CO) Brill Wolfgang K. D. (Schopfheim DEX) Yau Eric (Mercer Island WA) Ma Michael (New York NY) Nielsen John (Horsholm DKX), Nucleoside thiophosphoramidites.
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  612. Letsinger Robert L. (Wilmette IL), Nucleoside trichlorodimethylethyl phosphite esters.
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  613. Bergmann,Frank; Donner,Horst; Von Der Eltz,Herbert; Heindl,Dieter; Herdewijn,Piet, Nucleotide analogs with six-membered rings.
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  614. Fodor,Stephen P. A.; Stryer,Lubert; Read,J. Leighton; Pirrung,Michael C., Nucleotides and analogs having photoremovable protecting groups.
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  615. Fodor Stephen P. A. ; Stryer Lubert ; Read J. Leighton ; Pirrung Michael C., Nucleotides and analogs having photoremoveable protecting groups.
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  616. Dayton, Christopher L. G.; Galhardo, Flavio Da Silva; Barton, Nelson; Hitchman, Tim; Lyon, Jonathan; O'Donoghue, Eileen; Wall, Mark A., Oil degumming methods.
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  618. Ravikumar, Vasulinga T.; Capaldi, Daniel C.; Cole, Douglas L., Oligomer phosphoramidite compositions and processes for synthesizing the same.
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  619. Swayze, Eric E.; Bhat, Balkrishen; Lima, Walter F.; Prakash, Thazha P.; Kinberger, Garth A., Oligomeric compounds and methods.
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  620. Swayze, Eric E.; Bhat, Balkrishen; Lima, Walter F.; Prakash, Thazha P.; Kinberger, Garth A., Oligomeric compounds and methods.
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  621. Bhat, Balkrishen; Dande, Prasad; Prakash, Thazha P.; Allerson, Charles; Swayze, Eric E.; Griffey, Richard H., Oligomeric compounds comprising 4′-thionucleosides for use in gene modulation.
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  622. Oestergaard, Michael; Swayze, Eric E.; Seth, Punit P., Oligomeric compounds comprising alpha-beta-constrained nucleic acid.
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  623. Swayze, Eric E.; Siwkowski, Andrew M.; Seth, Punit P.; Prakash, Thazha P., Oligomeric compounds comprising tricyclic nucelosides and methods for their use.
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  624. Swayze, Eric E.; Siwkowski, Andrew M.; Seth, Punit P.; Prakash, Thazha P., Oligomeric compounds comprising tricyclic nucelosides and methods for their use.
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  625. Swayze, Eric E.; Siwkowski, Andrew M.; Seth, Punit P.; Prakash, Thazha P., Oligomeric compounds comprising tricyclic nucleosides and methods for their use.
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  626. Seth, Punit P.; Swayze, Eric E., Oligomeric compounds having at least one neutrally linked terminal bicyclic nucleoside.
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  627. Cook,Phillip Dan; Manoharan,Muthiah, Oligonucleolotides having site specific chiral phosphorothioate internucleoside linkages.
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  628. Reinherz, Ellis L.; Brusic, Vladimir; Zhang, Guanglan; Keskin, Derin Benerci; Deluca, David; Lin, Honghuang, Oligonucleotide array for tissue typing.
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  629. Woolf, Tod; Taylor, Margaret, Oligonucleotide compositions with enhanced efficiency.
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  630. Woolf, Tod; Taylor, Margaret, Oligonucleotide compositions with enhanced efficiency.
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  631. Woolf, Tod; Taylor, Margaret, Oligonucleotide compositions with enhanced efficiency.
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  632. Woolf, Tod; Taylor, Margaret, Oligonucleotide compositions with enhanced efficiency.
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  633. Brown, Bob D.; Riley, Timothy A., Oligonucleotide probes and primers comprising universal bases for diagnostic purposes.
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  634. Moore,Max N.; Andrade,Mark; Carty,Recaldo; Scozzari,Anthony; Krotz,Achim, Oligonucleotide synthesis with alternative solvents.
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  635. Zupi Gabriella,ITX, Oligonucleotide treatments and compositions for human melanoma.
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  636. Phillip Dan Cook ; Muthiah Manoharan, Oligonucleotides having site specific chiral phosphorothioate internucleoside linkages.
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  637. Crooke, Stanley T., Oligoribonucleotides and ribonucleases for cleaving RNA.
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  638. Scaringe Stephen A., Orthoester protecting groups.
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  639. Scaringe, Stephen, Orthoester protecting groups.
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  640. Scaringe Stephen ; Caruthers Marvin H., Orthoester protecting groups in RNA synthesis.
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  641. Scaringe Stephen ; Caruthers Marvin H., Orthoester reagents for use as protecting groups in oligonucleotide synthesis.
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  642. Leger, Andrew; Wentworth, Bruce; Nelson, Carol A.; Weeden, Timothy E.; Clayton, Nicholas; Cheng, Seng, Peptide-linked morpholino antisense oligonucleotides for treatment of myotonic dystrophy.
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  643. English, James T.; Schmidt, Francis J.; Smith, George P.; Morris, Roy O.; Bishop-Hurley, Sharon, Phage display selection of anti fungal peptides.
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  644. Von Der Mülbe, Florian; Hoerr, Ingmar; Pascolo, Steve, Pharmaceutical composition containing a stabilised mRNA optimised for translation in its coding regions.
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  645. Guzaev Andrei P. ; Manoharan Muthiah, Phosphate and thiophosphate protecting groups.
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  646. Guzaev, Andrei P.; Manoharan, Muthiah, Phosphate and thiophosphate protecting groups.
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  647. Guzaev, Andrei Pavel; Vvedenskiy, Vladimir Y., Phosphoramidite building blocks for sugar-conjugated oligonucleotides.
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  648. Imbach Jean-Louis,FRX ; Gosselin Gilles,FRX ; Rayner Bernard,FRX, Phosphotriester oligonucleotides, amidites and method of preparation.
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  649. Imbach Jean-Louis,FRX ; Gosselin Gilles,FRX ; Rayner Bernard,FRX ; Manoharan Muthiah, Phosphotriester oligonucleotides, amidities and method of preparation.
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  650. Michael C. Pirrung ; Lubert Stryer ; Stephen P. A. Fodor ; J. Leighton Read, Photolithographic and other means for manufacturing arrays.
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  651. Stephen P. A. Fodor ; J. Leighton Read ; Lubert Stryer ; Michael C. Pirrung, Photolithographic and other means for manufacturing arrays.
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  652. Goldberg,Steven L.; Cino,Paul M.; Patel,Ramesh N.; Nanduri,Venkata B.; Johnston,Robert M., Pichia pastoris formate dehydrogenase and uses therefor.
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  653. Haxo ; Jr. Francis Theodore ; Hoe Liang Boon, Pipetting device with pipette tip for solid phase reactions.
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  654. Jewett, Michael Christoper; Martin, Rey William; Hong, Seok Hoon; Kwon, Yong Chan; Des Soye, Benjamin James, Platforms for cell-free protein synthesis comprising extracts from genomically recoded E. coli strains having genetic knock-out mutations in release factor 1 (RF-1) and endA.
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  655. Stephen P. A. Fodor ; Lubert Stryer ; J. Leighton Read ; Michael C. Pirrung, Polymer arrays.
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  656. Moser, Michael James; Marshall, David J.; Prudent, James R.; Van Hout, Christopher V.; Larsen, Christine A., Polymerase inhibitor and method of using same.
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  657. Moser, Michael James; Marshall, David J.; Prudent, James R.; Van Hout, Cristopher V.; Larsen, Christine A., Polymerase inhibitor and method of using same.
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  658. Caruthers Marvin H. (Boulder CO) Brill Wolfgang K.-D. (Schopfheim DEX) Yau Eric (Mercer Island WA) Ma Michael (New York NY) Nielsen John (Horsholm DKX), Polynucleotide phosphorodithioate compounds.
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  659. Reenan,Robert A.; Rogina,Blanka; Helfand,Stephen L., Polynucleotides encoding cellular transporters and methods of use thereof.
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  660. Keimel, John G.; Kaytor, Michael David, Polynucleotides, vectors and methods for insertion and expression of transgenes.
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  661. Fodor, Stephen P. A.; Read, J. Leighton; Stryer, Lubert; Pirrung, Michael C., Polypeptide arrays.
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  662. Ronald D. Vale ; James J. Hartman, Polypeptides for the detection of microtubule depolymerization inhibitors.
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  663. Mori, Kenjiro; Maeta, Eri; Konishi, Tatsuya, Porous resin beads and method of producing nucleic acid using the same.
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  664. Bhat, Balkrishen; Swayze, Eric E.; Prakash, Thazha P.; Allerson, Charles; Dande, Prasad; Griffey, Richard H., Positionally modified siRNA constructs.
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  665. Topol, Eric J.; Muse, Evan; Connelly, Mark; Jatkoe, Timothy; Wang, Haiying, Predictive analysis for myocardial infarction.
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  666. Miller Paul S. (Baltimore MD) T\so Paul O. P. (Lutherville MD), Preparation of oligodeoxyribonucleoside alkyl or arylphosphonates.
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  667. Just George,CAX ; Xin Zhili ; Marsault Eric,CAX ; Jin Yi,CAX ; Wang Jianchao,CAX ; Manoharan Muthiah, Preparation of phosphorothioate and boranophosphate oligomers.
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  668. George Just CA; Zhili Xin ; Eric Marsault CA; Yi Jin CA; Jianchao Wang CA, Preparation of phosphorothioate oligomers.
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  669. Just George,CAX ; Xin Zhili,CAX ; Marsault Eric,CAX ; Jin Yi,CAX, Preparation of phosphorothioate oligomers.
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  670. Just George,CAX ; Xin Zhili,CAX ; Marsault Eric,CAX ; Jin Yi,CAX, Preparation of phosphorothioate oligomers.
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  671. Just, George; Xin, Zhili; Marsault, Eric; Jin, Yi, Preparation of phosphorothioate oligomers.
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  672. Just, George; Xin, Zhili; Marsault, Eric; Jin, Yi; Wang, Jianchao, Preparation of phosphorothioate oligomers.
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  673. Pease R. Fabian ; McGall Glenn ; Goldberg Martin J. ; Rava Richard P. ; Fodor Stephen P. A. ; Goss Virginia ; Stryer Lubert ; Winkler James L., Printing molecular library arrays.
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  674. Pease, R. Fabian; McGall, Glenn; Goldberg, Martin J.; Rava, Richard P.; Fodor, Stephen P. A.; Goss, Virginia; Stryer, Lubert; Winkler, James L., Printing oligonucleotide arrays.
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  675. Stokes, Kristoffer K; Berg, Michael C; Lenhart, Joseph L, Process enhancement via stimuli responsive particle surfaces.
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  676. Song,Quanlai; Ross,Bruce, Process for manufacturing purified phosphorodiamidite.
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  677. Caruthers Marvin H. (Boulder CO) Beaucage Serge L. (Mountain View CA), Process for oligonucleo tide synthesis using phosphormidite intermediates.
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  678. Scozzari Anthony, Process for oligonucleotide synthesis.
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  679. Fran.cedilla.ois Chatelain FR; Viktor Kumarev FR, Process for preparing polynucleotides on a solid support.
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  680. Chatelain, Fran.cedilla.ois; Kumarev, Viktor, Process for preparing polynucleotides on a solid support and apparatus permitting its implementation.
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  681. Ishido Yoshiharu (Tokyo JPX) Kamaike Kazuo (Tokyo JPX), Process for synthesis of oligonucleotides and compound for forming polymeric protecting group.
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  682. Sanghvi, Yogesh S.; Song, Quanlai, Process for the preparation of oligonucleotides.
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  683. Mellor,Ben James; Wellings,Donald Alfred; Douglas,Mark Edward, Process for the preparation of phosphorothioate oligonucleotides.
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  684. Frank Ronald (Wolfenbttel DEX) Heikens Wiebke (Braunschweig DEX), Process for the simultaneous synthesis of several oligonucleotides on a solid phase.
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  685. Capaldi Daniel C. ; Ravikumar Vasulinga T., Process for the synthesis of oligomeric compounds.
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  686. Capaldi Daniel C. ; Ravikumar Vasulinga T., Process for the synthesis of oligomeric compounds.
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  687. Cheruvallath Zacharia S. ; Ravikumar Vasulinga T. ; Cole Douglas L., Process for the synthesis of oligomeric compounds.
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  688. Cheruvallath, Zacharia S.; Ravikumar, Vasulinga T.; Cole, Douglas L., Process for the synthesis of oligomeric compounds.
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  689. Ravikumar Vasulinga T., Process for the synthesis of oligomeric compounds.
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  690. Ravikumar, Vasulinga T.; Manoharan, Muthiah; Capaldi, Daniel C.; Krotz, Achim; Cole, Douglas L.; Guzaev, Andrei, Process for the synthesis of oligomeric compounds.
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  691. Ravikumar,Vasulinga T.; Manoharan,Muthiah; Capaldi,Daniel C.; Krotz,Achim; Cole,Douglas L.; Guzaev,Andrei, Process for the synthesis of oligomeric compounds.
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  692. Ravikumar,Vasulinga T.; Manoharan,Muthiah; Capaldi,Daniel C.; Krotz,Achim; Cole,Douglas L.; Guzaev,Andrei, Process for the synthesis of oligomeric compounds.
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  693. Ravikumar,Vasulinga T.; Manoharan,Muthiah; Capaldi,Daniel C.; Krotz,Achim; Cole,Douglas L.; Guzaev,Andrei, Process for the synthesis of oligomeric compounds.
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  694. Ravikumar,Vasulinga; Manoharan,Muthiah; Capaldi,Daniel C.; Krotz,Achim; Cole,Douglas L.; Guzaev,Andrei P., Process for the synthesis of oligomeric compounds.
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  695. Vasulinga T. Ravikumar ; Muthiah Manoharan ; Daniel C. Capaldi ; Achim Krotz ; Douglas L. Cole ; Andrei Guzaev, Process for the synthesis of oligomeric compounds.
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  696. Zacharia S. Cheruvallath ; Vasulinga T. Ravikumar ; Douglas L. Cole, Process for the synthesis of oligomeric compounds.
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  697. Ravikumar Vasulinga T., Process for the synthesis of oligomeric phosphite, phosphodiester, phosphorothioate and phosphorodithioate compounds.
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  698. Leuck, Michael; Wolter, Andreas; Stumpe, Alfred, Process for the synthesis of oligonucleotides.
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  699. Klem Robert E. ; Marvin William B. ; Riley Timothy A., Process for the synthesis of oligonucleotides and analogs with low water oxidation step.
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  700. Ross,Bruce; Song,Quanlai, Process of purifying phosphoramidites.
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  701. Ehrich, Mathias; Nygren, Anders Olof Herman, Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses.
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  702. Ehrich, Mathias; Nygren, Anders Olof Herman; Jensen, Taylor Jacob, Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses.
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  703. Ravikumar Vasulinga ; Mulvey Dennis ; Cole Douglas L. ; Cook Phillip Dan, Processes and intermediates for phosphorous-containing covalent linkages.
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  704. Ehrich, Mathias; Mistro, Guy Del; Deciu, Cosmin; Chen, Yong Qing; McCullough, Ron Michael; Tim, Roger Chan, Processes and kits for identifying aneuploidy.
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  705. Ryan, Robert O.; Oda, Michael N., Processes for the preparation of lipophilic drug delivery vehicles.
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  706. Manoharan Muthiah, Processes for the synthesis of oligomeric compounds.
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  707. Ravikumar, Vasulinga T.; Capaldi, Daniel C.; Cole, Douglas L., Processes for the synthesis of oligomers using phosphoramidite compositions.
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  708. Manoharan, Muthiah; Guzaev, Andrei, Processes for the synthesis of oligonucleotide compounds.
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  709. Mori, Kenjiro; Konishi, Tatsuya, Production method of porous resin particle having hydroxyl group.
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  710. Stephen P. A. Fodor ; Dennis W. Solas ; William J. Dower, Products for detecting nucleic acids.
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  711. Stephen P. A. Fodor ; Dennis W. Solas ; William J. Dower, Products for detecting nucleic acids.
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  712. Cheruvallath Zacharia S. ; Capaldi Daniel C. ; Ravikumar Vasulinga T. ; Cole Douglas L., Protecting group for synthesizing oligonucleotide analogs.
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  713. Cheruvallath Zacharia S. ; Capaldi Daniel C. ; Ravikumar Vasulinga T. ; Cole Douglas L., Protecting group for synthesizing oligonucleotide analogs.
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  714. Cheruvallath Zacharia S. ; Capaldi Daniel C. ; Ravikumar Vasulinga T. ; Cole Douglas L., Protecting group for synthesizing oligonucleotide analogs.
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  715. Song,Quanlai; Ross,Bruce S., Protection of nucleosides.
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  716. Nagarajan,Sudha; Patton,John S.; Bennett,David B.; Greene,Joanne; Chiang,Hi Shi; Stults,Cheryl L. M.; Venthoye,Geraldine; Allen,Darrel LaVern; Hughes,Benjamin Lee; Stiff Torvik,Mary; Wolff,Ronald Kei, Pulmonary administration of dry powder formulations for treating infertility.
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  717. Nardone Glenn ; Nazarenko Irena ; Boal Jila, Pyrimidines linked to a quencher.
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  718. Nygren, Anders, Quantification of a minority nucleic acid species.
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  719. Nygren, Anders, Quantification of a minority nucleic acid species.
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  720. Nygren, Anders, Quantification of a minority nucleic acid species.
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  721. Lerer, Bernard; Greenbaum, Lior, RGS2 genotypes associated with extrapyramidal symptoms induced by antipsychotic medication.
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  722. Behlke, Mark Aaron; Rose, Scott D.; Dobosy, Joseph; Walder, Joseph Alan, RNase H-based assays utilizing modified RNA monomers.
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  723. Walder, Joseph Alan; Behlke, Mark Aaron; Rose, Scott D.; Dobosy, Joseph R.; Rupp, Susan M., RNase H-based assays utilizing modified RNA monomers.
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  724. Walder, Joseph Alan; Behlke, Mark Aaron; Rose, Scott; Dobosy, Joesph, RNase H-based assays utilizing modified RNA monomers.
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  725. Walder, Joseph Alan; Behlke, Mark Aaron; Rose, Scott; Dobosy, Joseph, RNase H-based assays utilizing modified RNA monomers.
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  726. Fields, Patricia; McQuiston, John R.; Fitzgerald Leaumont, Collette, Rapid Salmonella serotyping assay.
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  727. Fields, Patricia; McQuiston, John R.; Fitzgerald Leaumont, Collette, Rapid Salmonella serotyping assay.
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  728. Fields, Patricia; McQuiston, John R.; Fitzgerald Leaumont, Collette, Rapid salmonella serotyping assay.
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  729. Cheruvallath Zacharia S. ; Ravikumar Vasulinga T. ; Cole Douglas L. ; Capaldi Daniel C., Reagent useful for synthesizing sulfurized oligonucleotide analogs.
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  730. Cheruvallath Zacharia S. ; Ravikumar Vasulinga T. ; Cole Douglas L. ; Capaldi Daniel C., Reagent useful for synthesizing sulfurized oligonucleotide analogs.
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  731. Zacharia S. Cheruvallath ; Vasulinga T. Ravikumar ; Douglas L. Cole ; Daniel C. Capaldi, Reagent useful for synthesizing sulfurized oligonucleotide analogs.
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  732. Prudent, James R.; Sherrill, Christopher B., Reagents for the improved synthesis of isoguanosine containing oligonucleotides.
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  733. Afonina,Irina A.; Belousov,Yevgeniy S.; Dempcy,Robert O.; Kutyavin,Igor V.; Lokhov,Sergey G.; Lukhtanov,Eugeny A., Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis.
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  734. Afonina,Irina A.; Belousov,Yevgeniy S.; Dempcy,Robert O.; Kutyavin,Igor V.; Lokhov,Sergey G.; Lukhtanov,Eugeny A., Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis.
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  735. Lokhov, Sergey; Lukhtanov, Eugene, Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis.
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  736. Saxena, Brij B.; Rathnam, Premila; Singh, Makul; Hao, Meirong, Recombinant bifunctional protein of human lutropin receptor and human chorionic gonadotropin B-subunit and uses thereof.
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  737. Saxena,Brij B.; Rathnam,Premila; Singh,Mukul; Hao,Meirong, Recombinant bifunctional protein of human lutropin receptor and human chorionic gonadotropin B-subunit and uses thereof.
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  738. Swartz, James R., Recombinant cellular iysate system for producing a product of interest.
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  739. Wang,Qi; Guan,Zhonghon; Baggot,Brendan O.; Hadfield,Kristen; Zhao,Jianmin; Edwards,Janice, Recombinant proteins containing repeating units.
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  740. Kempe Tomas, Recovery of oligonucleotides by gas phase cleavage.
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  741. Sanghvi Yogesh S. ; Guo Zhiqiang, Recovery of triarylmethyl halide protecting groups cleaved during oligonucleotide synthesis.
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  742. Schroeder, Benjamin G., Reduced representation bisulfite sequencing with diversity adaptors.
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  743. Bruinsma, Janelle J.; Shenoi, Hemanth D.; Domanico, Michael J.; Light, II, James P., Removal of PCR inhibitors.
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  744. Rottmann, William H.; Norris-Caneda, Kim H.; Zhang, Chunsheng, Reproductive ablation constructs.
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  745. Rottmann, William H.; Norris-Caneda, Kim H.; Zhang, Chunsheng, Reproductive ablation constructs.
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  746. Rottmann, William H.; Norris-Caneda, Kim H.; Zhang, Chunsheng, Reproductive ablation constructs.
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  747. Rottmann,William H.; Norris Caneda,Kim H.; Zhang,Chunsheng, Reproductive ablation constructs.
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  748. Myers,Andrew G.; Plowright,Alleyn T., Saframycins, analogues and uses thereof.
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  749. Ozbal, Can C.; Katz, Arrin; Jonas, Maxine, Sample injection system.
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