초록

A bone-equivalent, useful in the fabrication of prostheses, is disclosed which is prepared from a hydrated collagen lattice contracted by fibroblast cells and containing demineralized bone powder.

대표청구항 ▼

A bone-equivalent comprising a hydrated collagen lattice containing deminerlized bone powder and contracted with fibroblast cells. A method of forming a bone-equivalent, comprising: a. combining a collagen solution with demineralized bone powder and fibroblast cells under conditions to form a gel mi

A bone-equivalent comprising a hydrated collagen lattice containing deminerlized bone powder and contracted with fibroblast cells. A method of forming a bone-equivalent, comprising: a. combining a collagen solution with demineralized bone powder and fibroblast cells under conditions to form a gel mixture having demineralized bone powder and fibroblast cells dispersed within said gel mixture; b. maintaining the gel mixture prepared in step (a) under conditions which permit the contraction of said gel mixture to form a bone-equivalent.